D. Brooks

发表

Akt signaling as a mediator of cardiac adaptation to low birth weight.

Kimberley C. W. Wang, K. Botting, Song Zhang, 2017, The Journal of endocrinology.

An index case for the attenuated end of the mucopolysaccharidosis type VI clinical spectrum.

D. Brooks, L. Karageorgos, J. Hopwood, 2005, Molecular genetics and metabolism.

Mutational analysis of mucopolysaccharidosis type VI patients undergoing a phase II trial of enzyme replacement therapy.

D. Brooks, L. Karageorgos, J. Hopwood, 2004, Molecular genetics and metabolism.

Lysosomal storage disease: revealing lysosomal function and physiology.

D. Brooks, E. Parkinson-Lawrence, T. Shandala, 2010, Physiology.

Differential Response to Injury in Fetal and Adolescent Sheep Hearts in the Immediate Post-myocardial Infarction Period

D. Brooks, J. Morrison, M. Seed, 2019, Front. Physiol..

Alteration of cardiac glucose metabolism in association to low birth weight: experimental evidence in lambs with left ventricular hypertrophy.

Kimberley C. W. Wang, I. McMillen, D. Brooks, 2013, Metabolism: clinical and experimental.

Intranasal and epicutaneous administration of Toll-like receptor 7 (TLR7) agonists provides protection against influenza A virus-induced morbidity in mice

D. Brooks, S. Liong, S. Bozinovski, 2019, Scientific Reports.

Gentamicin-mediated suppression of Hurler syndrome stop mutations restores a low level of alpha-L-iduronidase activity and reduces lysosomal glycosaminoglycan accumulation.

J. Thompson, D. Bedwell, K. Keeling, 2001, Human molecular genetics.

Fetal growth restriction and the programming of heart growth and cardiac insulin‐like growth factor 2 expression in the lamb

Kimberley C. W. Wang, K. Botting, Song Zhang, 2011, The Journal of physiology.

Redox ratio in the left ventricle of the growth restricted fetus is positively correlated with cardiac output

M. Wiese, D. Brooks, J. Morrison, 2021, Journal of biophotonics.

Low birth weight activates the renin–angiotensin system, but limits cardiac angiogenesis in early postnatal life

D. Tosh, Kimberley C. W. Wang, K. Botting, 2015, Physiological reports.

proliferation kinetics in the fetal sheep heart Myocyte enlargement, differentiation, and

D. Tosh, Kimberley C. W. Wang, K. Botting, 2015 .

A Paradigm in Immunochemistry, Revealed by Monoclonal Antibodies to Spatially Distinct Epitopes on Syntenin-1

J. Logan, L. Butler, D. Brooks, 2019, International journal of molecular sciences.

Early origins of heart disease: Low birth weight and the role of the insulin‐like growth factor system in cardiac hypertrophy

Kimberley C. W. Wang, K. Botting, Song Zhang, 2012, Clinical and experimental pharmacology & physiology.

Role of Immune Serum in the Killing of Helicobacter pylori by Macrophages

D. Brooks, G. Borlace, R. Butler, 2010, Helicobacter.

Survival Outcomes of Nonsmall Cell Lung Cancer Patients Treated with Afatinib Who Are Affected by Early Adverse Events

J. Logan, A. Rowland, D. Brooks, 2021, Journal of oncology.

IGF-2R-Gαq signaling and cardiac hypertrophy in the low-birth-weight lamb.

D. Tosh, Kimberley C. W. Wang, Song Zhang, 2015, American journal of physiology. Regulatory, integrative and comparative physiology.

IGF-2R-Mediated Signaling Results in Hypertrophy of Cultured Cardiomyocytes from Fetal Sheep1

Kimberley C. W. Wang, K. Botting, D. Brooks, 2012, Biology of reproduction.

IGF-2 RG q signaling and cardiac hypertrophy in the low-birthweight lamb

D. Tosh, Kimberley C. W. Wang, I. McMillen, 2015 .

Early origins of heart disease: Low birth weight and determinants of cardiomyocyte endowment

K. Botting, D. Brooks, J. Morrison, 2012, Clinical and experimental pharmacology & physiology.

NOX2 oxidase expressed in endosomes promotes cell proliferation and prostate tumour development

C. Sobey, D. Brooks, E. Williams, 2018, Oncotarget.

Bright lights down under: Metal ion complexes turning the spotlight on metabolic processes at the cellular level

Martin J. Sweetman, D. Brooks, J. Morrison, 2017, Coordination Chemistry Reviews.

LC-MS/MS analysis of vitamin D3 metabolites in human serum using a salting-out based liquid-liquid extraction and DAPTAD derivatization.

M. Wiese, D. Brooks, P. Anderson, 2021, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Common antigenicity for two glycosidases

P. Meikle, D. Brooks, I. Callebaut, 2006, FEBS letters.

Activation of IGF‐2R stimulates cardiomyocyte hypertrophy in the late gestation sheep fetus

Kimberley C. W. Wang, D. Brooks, J. Morrison, 2012, The Journal of physiology.

Detecting metabolic differences in fetal and adult sheep adipose and skeletal muscle tissues

D. Brooks, J. Morrison, M. Seed, 2019, Journal of biophotonics.

Immunoquantification of the low abundance lysosomal enzymeN-acetylgalactosamine 4-sulphatase

D. Brooks, J. Hopwood, P. McCourt, 1990, Journal of Inherited Metabolic Disease.

Mutational analysis of 105 mucopolysaccharidosis type VI patients

D. Brooks, R. Giugliani, L. Karageorgos, 2007, Human mutation.

Spatial Properties of Reactive Oxygen Species Govern Pathogen-Specific Immune System Responses

D. Brooks, C. Porter, L. O’Neill, 2020, Antioxidants & redox signaling.

Mitochondrial Reactive Oxygen Species Contribute to Pathological Inflammation During Influenza A Virus Infection in Mice

J. McQualter, D. Brooks, S. Liong, 2020, Antioxidants & redox signaling.

Investigating Intracellular Localisation and Cytotoxicity Trends for Neutral and Cationic Iridium Tetrazolato Complexes in Live Cells.

P. Raiteri, D. Brooks, J. Morrison, 2017, Chemistry.

Laronidase Treatment of Mucopolysaccharidosis I

P. Meikle, D. Brooks, J. Hopwood, 2012, BioDrugs.

α-L-Iduronidase and enzyme replacement therapy for mucopolysaccharidosis I

D. Brooks, 2002, Expert opinion on biological therapy.

Processing of normal lysosomal and mutant N-acetylgalactosamine 4-sulphatase: BiP (immunoglobulin heavy-chain binding protein) may interact with critical protein contact sites.

M. Gething, D. Brooks, J. Hopwood, 1999, The Biochemical journal.

Altered trafficking and turnover of LAMP-1 in Pompe disease-affected cells.

P. Meikle, D. Brooks, J. Hopwood, 1999, Molecular genetics and metabolism.

Targeting prostate cancer cells with genetically engineered polypeptide-based micelles displaying gastrin-releasing peptide.

Wei Zhang, D. Brooks, F. Lam, 2016, International journal of pharmaceutics.

Long-term clinical progress in bone marrow transplanted mucopolysaccharidosis type I patients with a defined genotype

C. P. Morris, H. Scott, D. Brooks, 1993, Journal of Inherited Metabolic Disease.

Enzyme Replacement Therapy in Mucopolysaccharidosis I: Altered Distribution and Targeting of α-l-Iduronidase in Immunized Rats

D. Brooks, J. Hopwood, C. Turner, 2000 .

Synthesis and Characterisation of First Generation Luminescent Lanthanide Complexes Suitable for Being Adapted for Uptake via the Mannose Receptor

D. Brooks, S. Plush, G. Borlace, 2013 .

Rhenium(I) conjugates as tools for tracking cholesterol in cells

J. O’Leary, D. Brooks, S. Plush, 2022, Metallomics : integrated biometal science.

The trans-Golgi network accessory protein p56 promotes long-range movement of GGA/clathrin-containing transport carriers and lysosomal enzyme sorting.

J. Bonifacino, D. Brooks, P. Burgos, 2007, Molecular biology of the cell.

Monocyte and Macrophage Killing of Helicobacter pylori: Relationship to Bacterial Virulence Factors

D. Brooks, G. Borlace, R. Butler, 2008, Helicobacter.

Exocytosis is impaired in mucopolysaccharidosis IIIA mouse chromaffin cells

D. Brooks, J. Hopwood, K. Hemsley, 2012, Neuroscience.

Two site-directed mutations abrogate enzyme activity but have different effects on the conformation and cellular content of the N-acetylgalactosamine 4-sulphatase protein.

C. P. Morris, D. Brooks, J. Hopwood, 1995, The Biochemical journal.

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy

S. Lewin, J. O’Leary, C. Sobey, 2017, Nature Communications.

Influenza A virus causes maternal and fetal pathology via innate and adaptive vascular inflammation in mice

J. O’Leary, D. Brooks, S. Liong, 2020, Proceedings of the National Academy of Sciences.

Development of a 13C Stable Isotope Assay for Dipeptidyl Peptidase-4 Enzyme Activity A New Breath Test for Dipeptidyl Peptidase Activity

D. Brooks, C. Abbott, R. Yazbeck, 2019, Scientific Reports.

An improved method for the purification of IgG monoclonal antibodies from culture supernatants.

D. Brooks, J. Hopwood, T. Bradford, 1992, Journal of immunological methods.

Immunoquantification of α-Galactosidase: Evaluation for the Diagnosis of Fabry Disease

P. Meikle, D. Brooks, J. Hopwood, 2004 .

Immunoquantification of alpha-galactosidase: evaluation for the diagnosis of Fabry disease.

P. Meikle, D. Brooks, J. Hopwood, 2004, Clinical chemistry.

Novel endosomal NOX2 oxidase inhibitor ameliorates pandemic influenza A virus‐induced lung inflammation in mice

D. Brooks, R. Vlahos, S. Selemidis, 2019, Respirology.

Effect of Age on Fructose Malabsorption in Children Presenting With Gastrointestinal Symptoms

K. Dowling, D. Brooks, G. Davidson, 2011, Journal of pediatric gastroenterology and nutrition.

Replacement therapy in Mucopolysaccharidosis type VI: advantages of early onset of therapy.

J. Lemontt, D. Brooks, J. Hopwood, 2003, Molecular genetics and metabolism.

Enzyme replacement therapy in a feline model of Maroteaux-Lamy syndrome.

D. Brooks, N. Fazzalari, J. Hopwood, 1996, The Journal of clinical investigation.

Human N-acetylgalactosamine-4-sulphatase biosynthesis and maturation in normal, Maroteaux-Lamy and multiple-sulphatase-deficient fibroblasts.

J. Taylor, D. Brooks, J. Hopwood, 1990, The Biochemical journal.

Developmental changes and fructose absorption in children: effect on malabsorption testing and dietary management.

D. Brooks, D. Moore, R. Butler, 2013, Nutrition reviews.

Unprecedented staining of polar lipids by a luminescent rhenium complex revealed by FTIR microspectroscopy in adipocytes.

P. A. Lay, D. Brooks, S. Plush, 2016, Molecular bioSystems.

Helicobacter pylori phagosome maturation in primary human macrophages

D. Brooks, G. Borlace, R. Butler, 2011, Gut pathogens.

Absence of α-galactosidase cross-correction in Fabry heterozygote cultured skin fibroblasts.

P. Meikle, D. Brooks, N. Mellett, 2015, Molecular genetics and metabolism.

Protein processing:

D. Brooks, 1997, FEBS letters.

Photophysical and Biological Properties of Iridium Tetrazolato Complexes Functionalised with Fatty Acid Chains

D. Brooks, M. Falasca, A. Ranieri, 2020, Inorganics.

Identification, expression, and biochemical characterization of N-acetylgalactosamine-4-sulfatase mutations and relationship with clinical phenotype in MPS-VI patients.

D. Brooks, J. Hopwood, T. Litjens, 1996, American journal of human genetics.

Mass spectrometric quantification of glycogen to assess primary substrate accumulation in the Pompe mouse.

P. Meikle, D. Brooks, J. Hopwood, 2012, Analytical biochemistry.

Stabilising normal and mis‐sense variant α‐glucosidase

P. Meikle, D. Brooks, J. Hopwood, 2006 .

Identification and molecular characterization of α‐L‐iduronidase mutations present in mucopolysaccharidosis type I patients undergoing enzyme replacement therapy

D. Brooks, J. Hopwood, P. Clements, 2004 .

Glycolysis and the Pentose Phosphate Pathway Promote LPS-Induced NOX2 Oxidase- and IFN-β-Dependent Inflammation in Macrophages

J. O’Leary, D. Brooks, S. Liong, 2022, Antioxidants.

Identification of mutations in the alpha-L-iduronidase gene (IDUA) that cause Hurler and Scheie syndromes.

C. P. Morris, H. Scott, D. Brooks, 1993, American journal of human genetics.

Human alpha-L-iduronidase. 1. Purification, monoclonal antibody production, native and subunit molecular mass.

D. Brooks, J. Hopwood, P. Clements, 1985, European journal of biochemistry.

Endothelial NOX4 Oxidase Negatively Regulates Inflammation and Improves Morbidity During Influenza A Virus Lung Infection in Mice

J. O’Leary, D. Brooks, A. Shah, 2022, Frontiers in Cellular and Infection Microbiology.

A membrane protein primarily associated with the lysosomal compartment.

D. Brooks, J. Hopwood, S. Carlsson, 1997, Biochimica et biophysica acta.

In Vivo Delivery of Human α-l-Iduronidase in Mice Implanted with Neo-Organs

O. Danos, D. Brooks, J. Hopwood, 1995 .

Drug induced exocytosis of glycogen in Pompe disease.

P. Meikle, D. Brooks, J. Hopwood, 2016, Biochemical and biophysical research communications.

Therapeutic Targeting of Endosome and Mitochondrial Reactive Oxygen Species Protects Mice From Influenza Virus Morbidity

Kylie M. Quinn, J. O’Leary, D. Brooks, 2022, Frontiers in Pharmacology.

Chromosomal Localization of the Human a-L-iduronidase Gene (IDUA) to 4pl6.3

D. Callen, D. Brooks, Baker, 2006 .

Glycogen Exocytosis from Cultured Pompe Skin Fibroblasts

P. Meikle, D. Brooks, J. Hopwood, 2015 .

Characterization and downstream mannose phosphorylation of human recombinant α-L-iduronidase produced in Arabidopsis complex glycan-deficient (cgl) seeds

N. Packer, D. Brooks, T. Haselhorst, 2013, Plant biotechnology journal.

Review: The immunochemical analysis of enzyme from mucopolysaccharidoses patients

D. Brooks, 1993, Journal of Inherited Metabolic Disease.

VAGINAL RADIOFRECUENCY FOR THE TREATMENT OF GENITAL ATROPHY IN PATIENTS WITH ONCOLOGICAL HISTORY IN A PUBLIC HOSPITAL. LIFE AFTER CANCER

D. Brooks, E. Dixon, N. Gleeson, 2021 .

599 Circulating tumour cells in breast and ovarian cancer: size-based isolation and ex vivo expansion

J. O’Leary, D. Brooks, E. Dixon, 2020, Translational research.

Neutral Re(I) Complex Platform for Live Intracellular Imaging.

D. Brooks, J. Morrison, S. Plush, 2021, Inorganic chemistry.

Analysis of N-acetylgalactosamine-4-sulfatase protein and kinetics in mucopolysaccharidosis type VI patients.

P. McCourt, D. Brooks, J. Hopwood, 1991, American journal of human genetics.

Autologous transplantation of retrovirally transduced bone marrow or neonatal blood cells into cats can lead to long-term engraftment in the absence of myeloablation

J. Abkowitz, D. Brooks, J. Hopwood, 1999, Gene Therapy.

Mucopolysaccharidosis VI (Maroteaux-Lamy syndrome). An intermediate clinical phenotype caused by substitution of valine for glycine at position 137 of arylsulfatase B.

C. Peters, K. von Figura, D. Brooks, 1991, The Journal of biological chemistry.

Norbornane-based cationic antimicrobial peptidomimetics targeting the bacterial membrane.

D. Brooks, Michael Thomas, R. Nation, 2018, European journal of medicinal chemistry.

Intracellular distribution and stability of a luminescent rhenium(i) tricarbonyl tetrazolato complex using epifluorescence microscopy in conjunction with X-ray fluorescence imaging.

B. Lai, D. Brooks, S. Vogt, 2017, Metallomics : integrated biometal science.

Detection of mucopolysaccharidosis type II by measurement of iduronate-2-sulfatase in dried blood spots and plasma samples.

P. Meikle, D. Brooks, J. Hopwood, 2006, Clinical chemistry.

Immune tolerance after long-term enzyme-replacement therapy among patients who have mucopolysaccharidosis I

D. Brooks, J. Hopwood, E. Kakkis, 2003, The Lancet.

Genotype-phenotype correlations in mucopolysaccharidosis type I using enzyme kinetics, immunoquantification and in vitro turnover studies.

D. Brooks, J. Hopwood, W. Kleijer, 1998, Biochimica et biophysica acta.

α-l-iduronidase in normal and mucopolysaccharidosis-type-I human skin fibroblasts

J. Taylor, D. Brooks, J. Hopwood, 1991 .

Neonatal gene therapy with a gamma retroviral vector in mucopolysaccharidosis VI cats.

D. Brooks, T. O'Malley, M. Haskins, 2012, Molecular therapy : the journal of the American Society of Gene Therapy.

Synthesis, photophysical and cellular characterisation of folate and methotrexate labelled luminescent lanthanide complexes.

D. Brooks, S. Plush, Zhangli Du, 2018, Journal of inorganic biochemistry.

Immune response to enzyme replacement therapy: clinical signs of hypersensitivity reactions and altered enzyme distribution in a high titre rat model.

D. Brooks, J. Hopwood, B. King, 1998, Biochimica et biophysica acta.

Diagnosis of lysosomal storage disorders: evaluation of lysosome-associated membrane protein LAMP-1 as a diagnostic marker.

P. Meikle, D. Brooks, L. Karageorgos, 1997, Clinical chemistry.

Immunochemical analysis of CD107a (LAMP-1).

Peter J Meikle, P. Meikle, D. Brooks, 2005, Cellular immunology.

Lysosomal biogenesis in lysosomal storage disorders.

P. Meikle, D. Brooks, L. Karageorgos, 1997, Experimental cell research.

Hurler syndrome: A patient with abnormally high levels of α-l-iduronidase protein

J. Taylor, G. Harper, D. Brooks, 1992 .

N-acetylgalactosamine-6-sulfatase protein detection in MPS IVA patient and unaffected control samples.

D. Brooks, J. Hopwood, E. Parkinson-Lawrence, 2007, Clinica chimica acta; international journal of clinical chemistry.

Significance of immune response to enzyme-replacement therapy for patients with a lysosomal storage disorder.

D. Brooks, J. Hopwood, Revecca Kakavanos, 2003, Trends in molecular medicine.

Glycosidase active site mutations in human α-L-iduronidase

B. Henrissat, J. Mornon, D. Brooks, 2001 .

Intestinal fructose transport and malabsorption in humans.

D. Brooks, R. Butler, Hilary F. Jones, 2011, American journal of physiology. Gastrointestinal and liver physiology.

Immunochemistry of Lysosomal Storage Disorders

P. Meikle, D. Brooks, J. Hopwood, 2005 .

At the Intersection of the Pathways for Exocytosis and Autophagy

D. Brooks, T. Shandala, G. Borlace, 2012 .

Targeting Evolutionary Conserved Oxidative Stress and Immunometabolic Pathways for the Treatment of Respiratory Infectious Diseases

D. Brooks, S. Liong, R. Vlahos, 2020, Antioxidants & redox signaling.

Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation

J. Gécz, M. Stratton, P. Futreal, 2007, Nature Genetics.

Syntaxin 7 is localized to late endosome compartments, associates with Vamp 8, and Is required for late endosome-lysosome fusion.

D. James, J. Luzio, M. Lindsay, 2000, Molecular biology of the cell.

Endosomal gene expression: a new indicator for prostate cancer patient prognosis?

L. Butler, D. Brooks, W. Watson, 2015, Oncotarget.

The role of miRNA regulation in fetal cardiomyocytes, cardiac maturation and the risk of heart disease in adults

Kimberley C. W. Wang, K. Botting, D. Brooks, 2018, The Journal of physiology.

A Drosophila Model to Image Phagosome Maturation

D. Brooks, T. Shandala, A. Sorvina, 2013, Cells.

Drosophila 14-3-3ε has a crucial role in anti-microbial peptide secretion and innate immunity

Angel F. Lopez, D. Brooks, T. Shandala, 2011, Journal of Cell Science.

Drosophila Pkaap regulates Rab4/Rab11-dependent traffic and Rab11 exocytosis of innate immune cargo

D. Brooks, T. Shandala, A. Sorvina, 2016, Biology Open.

Drosophila Pkaap regulates Rab4/Rab11-dependent traffic and Rab11 exocytosis of innate immune cargo

D. Brooks, T. Shandala, A. Sorvina, 2016, Biology Open.

Adverse Intrauterine Environment and Cardiac miRNA Expression

K. Botting, D. Brooks, J. Morrison, 2017, International journal of molecular sciences.

Molecular Machinery Regulating Exocytosis

D. Brooks, E. Parkinson-Lawrence, T. Shandala, 2012 .

Platelets, immune cells and the coagulation cascade; friend or foe of the circulating tumour cell?

D. Brooks, N. Brady, E. Dixon, 2021, Molecular cancer.

The role of the MAD2-TLR4-MyD88 axis in paclitaxel resistance in ovarian cancer

G. Blackshields, D. Brooks, A. McCann, 2020, PloS one.

Immunoquantification and enzyme kinetics of alpha-L-iduronidase in cultured fibroblasts from normal controls and mucopolysaccharidosis type I patients.

D. Brooks, J. Hopwood, P. McCourt, 1992, American journal of human genetics.

Lipid profiles of prostate cancer cells

P. A. Lay, D. Brooks, S. Plush, 2018, Oncotarget.

Human N-acetylgalactosamine-4-sulphate sulphatase. Purification, monoclonal antibody production and native and subunit Mr values.

D. Brooks, J. Hopwood, G. Gibson, 1987, The Biochemical journal.

Mucopolysaccharidosis VI (Maroteaux-Lamy syndrome): six unique arylsulfatase B gene alleles causing variable disease phenotypes.

C. Peters, K. von Figura, K. Figura, 1994, American journal of human genetics.

Evaluation of Small Molecule Drug Uptake in Patient-Derived Prostate Cancer Explants by Mass Spectrometry

J. Logan, L. Butler, M. Centenera, 2019, Scientific Reports.

A Practical Guide to Prepare and Synthetically Modify Graphene Quantum Dots

Martin J. Sweetman, D. Brooks, S. Plush, 2019, Advanced Functional Materials.

A role for altered phagosome maturation in the long-term persistence of Helicobacter pylori infection.

D. Brooks, M. Prodoehl, G. Borlace, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Mucopolysaccharidosis type VI (Maroteaux-Lamy syndrome): a Y210C mutation causes either altered protein handling or altered protein function of N-acetylgalactosamine 4-sulfatase at multiple points in the vacuolar network.

D. Brooks, J. Hopwood, T. Litjens, 2002, Biochemistry.

CDKI-73 Is a Novel Pharmacological Inhibitor of Rab11 Cargo Delivery and Innate Immune Secretion

Shudong Wang, D. Brooks, E. Parkinson-Lawrence, 2020, Cells.

I-Cell Disease

P. Meikle, D. Brooks, J. Hopwood, 2007 .

Identification and characterization of 13 new mutations in mucopolysaccharidosis type I patients.

D. Brooks, R. Giugliani, U. Matte, 2003, Molecular genetics and metabolism.

Identification and molecular characterization of alpha-L-iduronidase mutations present in mucopolysaccharidosis type I patients undergoing enzyme replacement therapy.

D. Brooks, J. Hopwood, P. Clements, 2004, Human mutation.

Stop-codon read-through for patients affected by a lysosomal storage disorder.

D. Brooks, J. Hopwood, V. Muller, 2006, Trends in molecular medicine.

Chromosomal localization of the human alpha-L-iduronidase gene (IDUA) to 4p16.3.

C. P. Morris, G. Sutherland, D. Callen, 1990, American journal of human genetics.

Iduronate-2-sulphatase protein detection in plasma from mucopolysaccharidosis type II patients.

D. Brooks, J. Hopwood, V. Muller, 2004, Molecular genetics and metabolism.

Analysis of normal and mutant iduronate-2-sulphatase conformation.

D. Brooks, J. Hopwood, E. Parkinson-Lawrence, 2005, The Biochemical journal.

Mutational analysis of mucopolysaccharidosis type VI patients undergoing a trial of enzyme replacement therapy

D. Brooks, L. Karageorgos, J. Hopwood, 2004, Human mutation.

α‐L‐iduronidase mutations (Q70X and P533R) associate with a severe Hurler phenotype

H. Scott, D. Brooks, J. Hopwood, 1992 .

Immunopurification and characterization of human alpha-L-iduronidase with the use of monoclonal antibodies.

D. Brooks, J. Hopwood, P. McCourt, 1989, The Biochemical journal.

Immune response to enzyme replacement therapy: 4-sulfatase epitope reactivity of plasma antibodies from MPS VI cats.

C. Bond, D. Brooks, J. Hopwood, 1999, Molecular genetics and metabolism.

Immunochemical characterization of feline and human N-acetylgalactosamine 4-sulfatase.

D. Brooks, J. Hopwood, G. Gibson, 1994, Biochemical medicine and metabolic biology.

Newborn screening for lysosomal storage disorders.

P. Meikle, D. Brooks, J. Hopwood, 2006, Molecular genetics and metabolism.

Juvenile form of mucopolysaccharidosis VI (Maroteaux-Lamy syndrome). A C-terminal extension causes instability but increases catalytic efficiency of arylsulfatase B.

C. Peters, K. von Figura, D. Brooks, 1994, The Journal of biological chemistry.

Development of an assay for the detection of mucopolysaccharidosis type VI patients using dried blood-spots.

P. Meikle, D. Brooks, J. Hopwood, 2005, Clinica chimica acta; international journal of clinical chemistry.

Prediction of neuropathology in mucopolysaccharidosis I patients.

P. Meikle, D. Brooks, J. Hopwood, 2005, Molecular genetics and metabolism.

Regulation of the lysosome-associated membrane protein in a sucrose model of lysosomal storage.

P. Meikle, D. Brooks, L. Karageorgos, 2000, Experimental cell research.

Proteome Analysis of Drosophila Mutants Identifies a Regulatory Role for 14-3-3ε in Metabolic Pathways.

P. Hoffmann, Angel F. Lopez, D. Brooks, 2017, Journal of proteome research.

Differential gene responses three days following infarction in the fetal and adolescent sheep heart.

D. Brooks, J. Morrison, M. Seed, 2020, Physiological genomics.

Is Small-bowel Bacterial Overgrowth an Underdiagnosed Disorder in Children With Gastrointestinal Symptoms?

D. Brooks, G. Davidson, R. Butler, 2011, Journal of pediatric gastroenterology and nutrition.

Atg9 is required for intraluminal vesicles in amphisomes and autolysosomes

D. Brooks, T. Shandala, I. R. Johnson, 2015, Biology Open.

A Molecular Probe for the Detection of Polar Lipids in Live Cells

P. A. Lay, N. Voelcker, D. Brooks, 2016, PloS one.

Protein: Cotranslational and Posttranslational Modification in Organelles

D. Brooks, E. Parkinson-Lawrence, T. Shandala, 2006 .

Imaging and lipidomics methods for lipid analysis in metabolic and cardiovascular disease

D. Brooks, J. Morrison, S. Plush, 2017, Journal of Developmental Origins of Health and Disease.

Aminoglycoside-Induced Premature Stop Codon Read-Through of Mucopolysaccharidosis Type I Patient Q70X and W402X Mutations in Cultured Cells.

D. Brooks, L. Karageorgos, J. Hopwood, 2014, JIMD reports.

alpha-L-iduronidase premature stop codons and potential read-through in mucopolysaccharidosis type I patients.

D. Sillence, D. Brooks, J. Hopwood, 2004, Journal of molecular biology.

Intranasal and epicutaneous administration of Toll-like receptor 7 (TLR7) agonists provides protection against influenza A virus-induced morbidity in mice

D. Brooks, S. Liong, S. Bozinovski, 2019, Scientific Reports.

Identification of Novel miRNAs Involved in Cardiac Repair Following Infarction in Fetal and Adolescent Sheep Hearts

D. Brooks, J. Morrison, M. Seed, 2020, Frontiers in Physiology.

Regulation of microRNA during cardiomyocyte maturation in sheep

K. Botting, Song Zhang, I. McMillen, 2015, BMC Genomics.

BIO013979 1345..1355

D. Brooks, T. Shandala, I. R. Johnson, 2015 .

Dysregulated fibronectin trafficking by Hsp90 inhibition restricts prostate cancer cell invasion

D. Lynn, L. Selth, L. Butler, 2018, Scientific Reports.

Altered Endosome Biogenesis in Prostate Cancer Has Biomarker Potential

L. Butler, R. Weigert, D. Brooks, 2014, Molecular Cancer Research.

model of congenital heart disease before pulmonary vascular remodeling in a lamb Delineating the angiogenic gene expression profile

D. Tosh, Kimberley C. W. Wang, K. Botting, 2015 .

Cross-coupling of amide and amide derivatives to umbelliferone nonaflates: synthesis of coumarin derivatives and fluorescent materials.

Martin J. Sweetman, D. Brooks, C. Sumby, 2020, The Journal of organic chemistry.

A fibre optic fluorescence sensor to measure redox level in tissues

Tanya M. Monro, Shahraam Afshar Vahid, Wen Qi Zhang, 2018, Micro + Nano Materials, Devices, and Applications.

A europium-based ‘off-on’ colourimetric detector of singlet oxygen

N. Voelcker, D. Brooks, Damien A. Sebben, 2017 .

The alpha-L-iduronidase mutations R89Q and R89W result in an attenuated mucopolysaccharidosis type I clinical presentation.

D. Brooks, J. Hopwood, L. Hein, 2003, Biochimica et biophysica acta.

Imaging nuclear, endoplasmic reticulum and plasma membrane events in real time

D. Brooks, S. Plush, P. Simpson, 2016, FEBS letters.

Modulation of the organelle specificity in Re(I) tetrazolato complexes leads to labeling of lipid droplets

D. Brooks, A. Anwer, E. Goldys, 2014 .

Fetal heart growth: IGF-1 and sex

Kimberley C. W. Wang, K. Botting, D. Brooks, 2009 .

Immune response to enzyme replacement therapy in lysosomal storage disorder patients and animal models.

D. Brooks, D. A. Brooks, 1999, Molecular genetics and metabolism.

Enzyme replacement therapy in Mucopolysaccharidosis VI: evidence for immune responses and altered efficacy of treatment in animal models.

D. Brooks, J. Hopwood, S. Byers, 1997, Biochimica et biophysica acta.

Immune response to enzyme replacement therapy: single epitope control of antigen distribution from circulation.

D. Brooks, E. Glaros, J. Hopwood, 2002, Molecular genetics and metabolism.

Newborn screening for lysosomal storage disorders.

P. Meikle, D. Brooks, J. Hopwood, 1999, The Southeast Asian journal of tropical medicine and public health.

In utero substrate restriction by placental insufficiency or maternal undernutrition decreases optical redox ratio in foetal perirenal fat

D. Brooks, J. Morrison, J. Lazniewska, 2021, Journal of biophotonics.

Synthesis and characterisation of folic acid based lanthanide ion probes

D. Brooks, S. Plush, G. Borlace, 2014 .

Development of a 13C Stable Isotope Assay for Dipeptidyl Peptidase-4 Enzyme Activity A New Breath Test for Dipeptidyl Peptidase Activity

D. Brooks, C. Abbott, R. Yazbeck, 2019, Scientific Reports.

Innate immunity and exocytosis of antimicrobial peptides

D. Brooks, T. Shandala, 2012, Communicative & integrative biology.

Bacterial challenge initiates endosome-lysosome response in Drosophila immune tissues

R. Weigert, D. Brooks, T. Shandala, 2013 .

Label‐free imaging of redox status and collagen deposition showing metabolic differences in the heart

D. Brooks, J. Morrison, M. Seed, 2018, Journal of biophotonics.

Development of an optical fiber‐based redox monitoring system for tissue metabolism

D. Brooks, S. Plush, J. Darby, 2022, Journal of biophotonics.

Dysregulated fibronectin trafficking by Hsp90 inhibition restricts prostate cancer cell invasion

D. Lynn, L. Selth, L. Butler, 2018, Scientific Reports.

Spectroscopic and molecular docking study of the interaction between neutral Re(I) tetrazolate complexes and bovine serum albumin.

D. Brooks, J. Lazniewska, S. Plush, 2021, Chemistry.

Immunochemistry of lysosomal storage disorders.

P. Meikle, D. Brooks, J. Hopwood, 2006, Clinical chemistry.