G. Seki

发表

Dual Regulation of Gluconeogenesis by Insulin and Glucose in the Proximal Tubules of the Kidney

M. Nangaku, T. Kadowaki, M. Sasaki, 2017, Diabetes.

Association between hepatitis B/C viral infection, chronic kidney disease and insulin resistance in individuals undergoing general health screening

K. Koike, G. Seki, R. Nagai, 2008, Hepatology research : the official journal of the Japan Society of Hepatology.

Localization of Na+-HCO-3 cotransporter (NBC-1) variants in rat and human pancreas.

G. Seki, H. Satoh, K. Tsukamoto, 2003, American journal of physiology. Cell physiology.

Insulin promotes sodium transport but suppresses gluconeogenesis via distinct cellular pathways in human and rat renal proximal tubules.

H. Kume, M. Nangaku, G. Seki, 2019, Kidney international.

Immunomodulation with eicosapentaenoic acid supports the treatment of autoimmune small-vessel vasculitis

Kazuo Suzuki, G. Seki, M. Arita, 2014, Scientific Reports.

Effects of atrial natriuretic peptide on glycerol induced acute renal failure in the rat.

G. Seki, K. Nosaka, K. Kurokawa, 1992, Japanese heart journal.

The acid-base regulation by renal proximal tubule

G. Seki, Masashi Suzuki, O. Yamazaki, 2013 .

Aberrantly Glycosylated IgA1 as a Factor in the Pathogenesis of IgA Nephropathy

G. Seki, M. Nagata, T. Fujita, 2011, Clinical & developmental immunology.

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor simvastatin ameliorates renal fibrosis through HOXA13–USAG-1 pathway

G. Seki, H. Ijichi, T. Fujita, 2012, Laboratory Investigation.

Association between Obesity and Chronic Kidney Disease in Japanese: Differences in Gender and Hypertensive Status?

K. Koike, G. Seki, R. Nagai, 2007, Hypertension Research.

Association between Cigarette Smoking and Chronic Kidney Disease in Japanese Men

K. Koike, G. Seki, R. Nagai, 2008, Hypertension Research.

Roles of MEK/ERK Pathway in Vascular and Renal Tubular Actions of Angiotensin II

K. Koike, G. Seki, T. Fujita, 2009 .

Stimulatory effect of insulin on renal proximal tubule sodium transport is preserved in type 2 diabetes with nephropathy.

H. Kume, Y. Homma, G. Seki, 2015, Biochemical and biophysical research communications.

The Effects of Insulin Resistance and Inflammation on Renal Proximal Tubule Sodium Transport and Hypertension

G. Seki, Masashi Suzuki, S. Horita, 2013 .

Insulin Resistance, Obesity, Hypertension, and Renal Sodium Transport

K. Koike, G. Seki, T. Fujita, 2011, International journal of hypertension.

Regulatory roles of nitric oxide and angiotensin II on renal tubular transport.

G. Seki, Masashi Suzuki, O. Yamazaki, 2014, World journal of nephrology.

BASIC AND TRANSLATIONAL—PANCREAS Irbit Mediates Synergy Between Ca 2D and cAMP Signaling Pathways During Epithelial Transport in Mice

K. Mikoshiba, T. Abe, H. Kiyonari, 2013 .

Irbit mediates synergy between ca(2+) and cAMP signaling pathways during epithelial transport in mice.

K. Mikoshiba, T. Abe, H. Kiyonari, 2013, Gastroenterology.

IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway.

K. Mikoshiba, I. So, S. Muallem, 2011, The Journal of clinical investigation.

Preserved Na/HCO3 cotransporter sensitivity to insulin may promote hypertension in metabolic syndrome.

H. Kume, Y. Homma, G. Seki, 2015, Kidney international.

Roles of insulin receptor substrates in insulin-induced stimulation of renal proximal bicarbonate absorption.

Y. Terauchi, T. Kadowaki, Y. Endo, 2005, Journal of the American Society of Nephrology : JASN.

Roles of Renal Proximal Tubule Transport in Acid/Base Balance and Blood Pressure Regulation

G. Seki, Masashi Suzuki, O. Yamazaki, 2014, BioMed research international.

Role of renal proximal tubule transport in thiazolidinedione-induced volume expansion.

Y. Endo, G. Seki, T. Fujita, 2012, World journal of nephrology.

Thiazolidinediones enhance sodium-coupled bicarbonate absorption from renal proximal tubules via PPARγ-dependent nongenomic signaling.

H. Kume, Y. Homma, T. Kadowaki, 2011, Cell metabolism.

Roles of ERK and cPLA2 in the angiotensin II-mediated biphasic regulation of Na+-HCO3(-) transport.

Takao Shimizu, Y. Endo, G. Seki, 2008, Journal of the American Society of Nephrology : JASN.

A stop-flow microperfusion technique for rapid determination of HCO3– absorption/H+ secretion by isolated renal tubules

G. Seki, I. Samaržija, E. Frömter, 1999, Pflügers Archiv.

Partial recovery of in vivo function by improved incubation conditions of isolated renal proximal tubule.

G. Seki, I. Samaržija, E. Frömter, 1997, Pflügers Archiv.

Incubation in tissue culture media allows isolated rabbit proximal tubules to regain in-vivo-like transport function: response of HCO3– absorption to norepinephrine

G. Seki, I. Samaržija, E. Frömter, 2000, Pflügers Archiv.

Biphasic regulation of renal proximal bicarbonate absorption by luminal AT(1A) receptor.

T. Sugaya, G. Seki, A. Goto, 2003, Journal of the American Society of Nephrology : JASN.

Distribution of β2‐adrenergic receptor mRNA expression along the hamster nephron segments

G. Seki, K. Kurokawa, A. Nakao, 1993, FEBS letters.

Biphasic Regulation of Na+-HCO3− Cotransporter by Angiotensin II Type 1A Receptor

T. Sugaya, G. Seki, A. Goto, 2002, Hypertension.

Mutations in SLC4A4 cause permanent isolated proximal renal tubular acidosis with ocular abnormalities

Y. Kanai, G. Seki, H. Satoh, 1999, Nature Genetics.

Arachidonic Acid Metabolites Inhibit the Stimulatory Effect of Angiotensin II in Renal Proximal Tubules

Takao Shimizu, Y. Endo, G. Seki, 2008, Hypertension Research.

Angiotensin II dose-dependently stimulates human renal proximal tubule transport by the nitric oxide/guanosine 3',5'-cyclic monophosphate pathway.

H. Kume, Y. Homma, A. Nishiyama, 2014, Journal of the American Society of Nephrology : JASN.

Roles of Ca2+ and PKC in regulation of acid/base transport in isolated proximal tubules.

G. Seki, K. Nosaka, K. Kurokawa, 1996, The American journal of physiology.

Interaction of Membrane Skeletal Protein, Protein 4.1B and p55, and Sodium Bicarbonate Cotransporter1 in Mouse Renal S1-S2 Proximal Tubules

M. Komada, G. Seki, Tatsuo Suzuki, 2007, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Successful treatment of acute kidney injury in patients with idiopathic nephrotic syndrome using human atrial natriuretic Peptide.

M. Nangaku, G. Seki, T. Fujita, 2014, Internal medicine.

C1q-binding immunoglobulin G in MRL/l mice consists of immune complexes containing antibodies to DNA.

G. Seki, K. Kurokawa, M. Mannik, 1995, Clinical immunology and immunopathology.

Mutational and functional analysis of SLC4A4 in a patient with proximal renal tubular acidosis

G. Seki, H. Endou, A. Kudo, 2004, Pflügers Archiv.

Novel nonsense mutation in the Na+/HCO3- cotransporter gene (SLC4A4) in a patient with permanent isolated proximal renal tubular acidosis and bilateral glaucoma.

Y. Takeshima, G. Seki, H. Endou, 2001, Journal of the American Society of Nephrology : JASN.

SLC4A4 compound heterozygous mutations in exon–intron boundary regions presenting with severe proximal renal tubular acidosis and extrarenal symptoms coexisting with Turner’s syndrome: a case report

S. Tsuji, M. Nangaku, G. Seki, 2018, BMC Medical Genetics.

Unraveling the molecular pathogenesis of isolated proximal renal tubular acidosis.

G. Seki, T. Igarashi, J. Inatomi, 2002, Journal of the American Society of Nephrology : JASN.

FRONTIERS IN NEPHROLOGY Unraveling the Molecular Pathogenesis of Isolated Proximal Renal Tubular Acidosis

G. Seki, T. Igarashi, J. Inatomi, 2002 .

Defective membrane expression of the Na+-HCO3− cotransporter NBCe1 is associated with familial migraine

K. Mikoshiba, W. van Paesschen, B. Bergmans, 2010, Proceedings of the National Academy of Sciences.

Long-term effects of LTB4 antagonist on lipid induced renal injury.

G. Seki, K. Nosaka, T. Shimizu, 1997, Kidney international. Supplement.

Functional coupling of V-ATPase and CLC-5

G. Seki, K. Moriya, Masashi Suzuki, 2017, World journal of nephrology.

Activation and Inactivation Mechanisms of Na-HCO 3 Cotransporter NBC 1

G. Seki, T. Fujita, Masashi Suzuki, 2008 .

Functional analysis of NBC1 mutants associated with proximal renal tubular acidosis and ocular abnormalities.

Y. Endo, G. Seki, L. Al-Gazali, 2005, Journal of the American Society of Nephrology : JASN.

Bacteremia in hemodialysis patients

G. Seki, K. Moriya, Masashi Suzuki, 2016, World journal of nephrology.

Effects of Nitric Oxide on Renal Proximal Tubular Na+ Transport

G. Seki, K. Moriya, Masashi Suzuki, 2017, BioMed research international.

Identification of dominant negative effect of L522P mutation in the electrogenic Na+–HCO3− cotransporter NBCe1

G. Seki, T. Fujita, Masashi Suzuki, 2013, Pflügers Archiv - European Journal of Physiology.

Physiological and pathophysiological roles of the electrogenic Na+-HCO3– cotransporter NBCe1

W. Paesschen, G. Seki, Shih-Hua Lin, 2011 .

Physiological and pathophysiological roles of the electrogenic Na +-cotransporter NBCe 1 3 HCO

W. Paesschen, G. Seki, Shih-Hua Lin, 2011 .

Functional characterization of nonsynonymous single nucleotide polymorphisms in the electrogenic Na+–HCO3− cotransporter NBCe1A

G. Seki, T. Fujita, Masashi Suzuki, 2011, Pflügers Archiv - European Journal of Physiology.

Quantifying porphobilinogen deaminase mRNA in microdissected nephron segments by a modified RT-PCR.

G. Seki, A. Goto, T. Fujita, 2002, Kidney international.

Detection and quantitation of EP3 prostaglandin E2 receptor mRNA along mouse nephron segments by RT-PCR.

G. Seki, T. Watanabe, K. Kurokawa, 1994, The American journal of physiology.

Pathophysiological Roles of Mutations in the Electrogenic Na+-HCO - Cotransporter NBCe1

G. Seki, Masashi Suzuki, O. Yamazaki, 2012 .

On the mechanism of bicarbonate exit from renal proximal tubular cells.

G. Seki, K. Yoshitomi, I. Samaržija, 1996, Kidney international.

Mechanism of [Ca2+]i increase by extracellular ATP in isolated rabbit renal proximal tubules.

G. Seki, K. Kurokawa, S. Uwatoko, 1996, The American journal of physiology.

Diversity of vancomycin-resistant enterococci in a low endemicity area.

G. Seki, M. Okazaki, K. Moriya, 2014, Journal of global antimicrobial resistance.

Severe metabolic acidosis causes early lethality in NBC1 W516X knock-in mice as a model of human isolated proximal renal tubular acidosis.

Shu-Wha Lin, G. Seki, Shih-Hua Lin, 2011, Kidney international.

Unexpected effect of the appetite-stimulating hormone ghrelin on ENaC: hunger for sodium?

G. Seki, 2013, Kidney international.

IRBIT, an inositol 1,4,5-trisphosphate receptor-binding protein, specifically binds to and activates pancreas-type Na+/HCO3- cotransporter 1 (pNBC1).

K. Mikoshiba, G. Seki, T. Fujita, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Immunoelectron microscopic localization of protein 4.1B in proximal S1 and S2 tubules of rodent kidneys

O. Ohara, G. Seki, N. Ohno, 2004, Medical Electron Microscopy.

The Na+-HCO3− cotransporter operates with a coupling ratio of 2 HCO3− to 1 Na+ in isolated rabbit renal proximal tubule

G. Seki, E. Frömter, S. Coppola, 1993, Pflügers Archiv.

Mutation of the Mg2+ transporter SLC41A1 results in a nephronophthisis-like phenotype.

T. Abe, T. Hurd, G. Ghiggeri, 2013, Journal of the American Society of Nephrology : JASN.

Thiazolidinediones and Edema: Recent Advances in the Pathogenesis of Thiazolidinediones-Induced Renal Sodium Retention

G. Seki, Masashi Suzuki, S. Horita, 2015, PPAR research.

Molecular mechanisms of renal and extrarenal manifestations caused by inactivation of the electrogenic Na+-HCO3− cotransporter NBCe1

G. Seki, Masashi Suzuki, T. Usui, 2013, Front. Physiol..

Functional Roles of Electrogenic Sodium Bicarbonate Cotransporter NBCe1 in Ocular Tissues

G. Seki, T. Fujita, Masashi Suzuki, 2012, The open ophthalmology journal.

Molecular basis of ocular abnormalities associated with proximal renal tubular acidosis.

M. Araie, G. Seki, M. Hara, 2001, The Journal of clinical investigation.

Functional and molecular evidence for Na+-HCO3– cotransporter in human corneal endothelial cells

M. Araie, G. Seki, T. Oshika, 1999, Pflügers Archiv.

Identification of dominant negative effect of L522P mutation in the electrogenic Na+–HCO3− cotransporter NBCe1

G. Seki, T. Fujita, Masashi Suzuki, 2013, Pflügers Archiv - European Journal of Physiology.

A pure chloride channel mutant of CLC-5 causes Dent’s disease via insufficient V-ATPase activation

D. Yamamoto, G. Seki, Masashi Suzuki, 2016, Pflügers Archiv - European Journal of Physiology.

Functional analysis of a novel missense NBC1 mutation and of other mutations causing proximal renal tubular acidosis

Y. Endo, G. Seki, T. Fujita, 2007, Pflügers Archiv - European Journal of Physiology.

Localization of NBC-1 variants in human kidney and renal cell carcinoma.

G. Seki, A. Kudo, T. Fujita, 2003, Biochemical and biophysical research communications.

Intracellular pH regulatory mechanism in a human renal proximal cell line (HKC-8): evidence for Na+/H+ exchanger, Cl–/HCO3– exchanger and Na+-HCO3– cotransporter

G. Seki, H. Satoh, K. Tsukamoto, 2000, Pflügers Archiv.

Human Sodium Phosphate Transporter 4 (hNPT4/SLC17A3) as a Common Renal Secretory Pathway for Drugs and Urate*

A. Taniguchi, H. Yamanaka, G. Seki, 2010, The Journal of Biological Chemistry.

Species differences in regulation of renal proximal tubule transport by certain molecules.

G. Seki, Masashi Suzuki, S. Horita, 2015, World journal of nephrology.

Relowering of Serum Na for Osmotic Demyelinating Syndrome

G. Seki, K. Takano, T. Fujita, 2012, Case reports in neurological medicine.

Selective Insulin Resistance in the Kidney

G. Seki, Masashi Suzuki, S. Horita, 2016, BioMed research international.

Unraveling the molecular basis of hereditary renal tubular acidosis

G. Seki, T. Igarashi, J. Inatomi, 2001, Clinical and Experimental Nephrology.

Localization of NBC1 Variants in Rat Kidney

Y. Endo, G. Seki, A. Kudo, 2006, Nephron Physiology.

Mechanism of anion permeation in the basolateral membrane of isolated rabbit renal proximal tubule S3 segment.

G. Seki, K. Kurokawa, S. Uwatoko, 1997, The American journal of physiology.

Acetazolamide inhibition of basolateral base exit in rabbit renal proximal tubule S2 segment

G. Seki, E. Frömter, 1992, Pflügers Archiv.

Therapeutic effect of prenatal alkalization and PTC124 in Na+/HCO3− cotransporter 1 p.W516* knock-in mice

G. Seki, T. Chau, C.-J. Cheng, 2015, Gene Therapy.

Evidence for conductive Cl- pathway in the basolateral membrane of rabbit renal proximal tubule S3 segment.

G. Seki, K. Kurokawa, S. Uwatoko, 1993, The Journal of clinical investigation.

Dopamine inhibits renal Na+:HCO3- cotransporter in rabbits and normotensive rats but not in spontaneously hypertensive rats.

G. Seki, T. Fujita, S. Uwatoko, 2000, Kidney international.

Functional role of a putative carbonic anhydrase II-binding domain in the electrogenic Na+-HCO3− cotransporter NBCe1 expressed in Xenopus oocytes

G. Seki, T. Fujita, Masashi Suzuki, 2011, Channels.

Acetazolamide inhibition of basolateral Cl−/HCO3− exchange in rabbit renal proximal tubule S3 segment

G. Seki, E. Frömter, 1992, Pflügers Archiv.

Activation of the basolateral Cl− conductance by cAMP in rabbit renal proximal tubule S3 segments

G. Seki, K. Kurokawa, Keij Suzuki, 1995, Pflügers Archiv.

Effect of parathyroid hormone on acid/base transport in rabbit renal proximal tubule S3 segment

G. Seki, K. Kurokawa, Keij Suzuki, 1993, Pflügers Archiv.

Acute Kidney Injury as a Risk Factor for Transplant Graft Failure

G. Seki, Masashi Suzuki, O. Yamazaki, 2014 .

Acute kidney injury as defined by the RIFLE criteria is a risk factor for kidney transplant graft failure

G. Seki, T. Fujita, S. Teraoka, 2012, Clinical transplantation.

The chloride/base exchanger in the basolateral cell membrane of rabbit renal proximal tubule S3 segment requires bicarbonate to operate

G. Seki, E. Frömter, 1990, Pflügers Archiv.

The long-term use of enalapril and hydrochlorothiazide in two novel mutations patients with Dent's disease type 1.

G. Seki, T. Igarashi, V. Koch, 2012, Jornal Brasileiro De Nefrologia.

Resolution of Henoch-Schönlein purpura nephritis after acquired IgA deficiency

G. Seki, M. Nagata, T. Fujita, 2010, Pediatric Nephrology.

Metabolic syndrome and insulin signaling in kidney

G. Seki, T. Fujita, Masashi Suzuki, 2011 .

Scleroderma renal crisis with pericardial effusion

G. Seki, T. Fujita, A. Tojo, 2011 .

Roles of Akt and SGK1 in the Regulation of Renal Tubular Transport

G. Seki, Masashi Suzuki, S. Horita, 2015, BioMed research international.

Association between Chronic Kidney Disease and Carotid Intima-Media Thickening in Individuals with Hypertension and Impaired Glucose Metabolism