J. L. Coloff

发表

Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells

G. Stephanopoulos, J. Albeck, J. Brugge, 2017, bioRxiv.

Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival

J. Rathmell, J. L. Coloff, S. R. Jacobs, 2008, Journal of leukocyte biology.

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

Gerald C. Chu, L. Chin, Yonghong Xiao, 2012, Cell.

Chaperone-mediated autophagy degrades mutant p53.

G. Kroemer, Junying Yuan, J. Brugge, 2013, Genes & development.

Identification of cancer genes that are independent of dominant proliferation and lineage programs

I. Harris, J. Brugge, J. L. Coloff, 2017, Proceedings of the National Academy of Sciences.

The Role of Proliferation in Determining Response to Neoadjuvant Chemotherapy in Breast Cancer: A Gene Expression–Based Meta-Analysis

E. Winer, W. Barry, J. Brugge, 2016, Clinical Cancer Research.

Metabolic changes promote rejection of oncogenic cells

J. Brugge, J. L. Coloff, 2017, Nature Cell Biology.

Molecular and Cellular Pathobiology the C-jun Nh 2 -terminal Kinase 2 Plays a Dominant Role in Human Epidermal Neoplasia

Jennifer Y. Zhang, J. Rathmell, J. L. Coloff, 2022 .

Extracellular matrix regulation of metabolism and implications for tumorigenesis.

J. Brugge, J. L. Coloff, A. Grassian, 2011, Cold Spring Harbor symposia on quantitative biology.

Starved epithelial cells uptake extracellular matrix for survival

Daniel S. Hitchcock, J. Brugge, C. Clish, 2017, Nature Communications.

Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1.

O. Ilkayeva, J. Rathmell, J. L. Coloff, 2007, Molecular and cellular biology.

Distinct Rates of Palmitate Turnover on Membrane-bound Cellular and Oncogenic H-Ras*

J. L. Coloff, J. Buss, Hui Zheng, 2003, Journal of Biological Chemistry.

Coping with the metabolic stress of leaving home

J. Brugge, J. L. Coloff, 2016, Cell Research.

Cell Cycle and Senescence Autophagy-Dependent Metabolic Reprogramming Sensitizes TSC 2-De fi cient Cells to the Antimetabolite 6-Aminonicotinamide

A. Choi, D. Kwiatkowski, J. Asara, 2013 .

Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability

O. Ilkayeva, C. Newgard, J. Rathmell, 2011, Molecular biology of the cell.

Oncogenic metabolic rewiring independent of proliferative control in human mammary epithelial cells

G. Stephanopoulos, J. Kelleher, M. V. Vander Heiden, 2022, bioRxiv.

The Diverse Functions of Non-Essential Amino Acids in Cancer

J. L. Coloff, Bo-hyun Choi, Jonathan L. Coloff, 2019, Cancers.

Akt Requires Glucose Metabolism to Suppress Puma Expression and Prevent Apoptosis of Leukemic T Cells*

O. Ilkayeva, G. Zambetti, J. Rathmell, 2010, The Journal of Biological Chemistry.

Aerobic glycolysis suppresses p53 activity to provide selective protection from apoptosis upon loss of growth signals or inhibition of BCR-Abl.

J. Rathmell, J. L. Coloff, Hugh S. Gannon, 2010, Cancer research.

Glucose Metabolism Attenuates p53 and Puma-dependent Cell Death upon Growth Factor Deprivation*

J. Rathmell, J. L. Coloff, Kai Cui, 2008, Journal of Biological Chemistry.

Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition.

D. Plas, J. Rathmell, J. L. Coloff, 2011, Cancer research.

ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP.

Gordon B Mills, David M Sabatini, G. Mills, 2016, Cancer research.

Autophagy-Dependent Metabolic Reprogramming Sensitizes TSC2-Deficient Cells to the Antimetabolite 6-Aminonicotinamide

A. Choi, D. Kwiatkowski, J. Asara, 2013, Molecular Cancer Research.

Correction to: SOX2 mediates metabolic reprogramming of prostate cancer cells

E. Platz, A. D. De Marzo, J. L. Coloff, 2022, Oncogene.

SOX2 Mediates Metabolic Reprogramming of Prostate Cancer Cells

A. D. De Marzo, J. L. Coloff, P. Mu, 2021, Oncogene.

Autophagy provides nutrients but can lead to Chop-dependent induction of Bim to sensitize growth factor-deprived cells to apoptosis.

O. Ilkayeva, J. Rathmell, J. L. Coloff, 2009, Molecular biology of the cell.

Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation.

Christian M. Metallo, G. Stephanopoulos, J. Brugge, 2011, Genes & development.

Lineage-specific silencing of PSAT1 induces serine auxotrophy and sensitivity to dietary serine starvation in luminal breast tumors

Tejas Mehta, J. L. Coloff, Taru E. Muranen, 2020, bioRxiv.

Differential Glutamate Metabolism in Proliferating and Quiescent Mammary Epithelial Cells.

S. Gygi, I. Harris, J. Brugge, 2016, Cell metabolism.

Combining Amine Metabolomics and Quantitative Proteomics of Cancer Cells Using Derivatization with Isobaric Tags

S. Gygi, R. Everley, J. L. Coloff, 2014, Analytical chemistry.

HIF1α and HIF2α Exert Distinct Nutrient Preferences in Renal Cells

W. Rathmell, J. Rathmell, J. L. Coloff, 2014, PloS one.

The Integration of Metabolism and Cell Death

J. Rathmell, J. L. Coloff, Yuxing Zhao, 2009 .

Glycogen Synthase Kinase 3α and 3β Mediate a Glucose-Sensitive Antiapoptotic Signaling Pathway To Stabilize Mcl-1

O. Ilkayeva, J. Rathmell, J. L. Coloff, 2007, Molecular and Cellular Biology.

Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion.

John G Doench, W. Hahn, J. Doench, 2019, Cell metabolism.

Correction: Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death

J. Yates, Junying Yuan, J. L. Coloff, 2016, The Journal of cell biology.

Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death

J. Yates, Junying Yuan, J. L. Coloff, 2015, The Journal of cell biology.

Differential substrate use in EGF‐ and oncogenic KRAS‐stimulated human mammary epithelial cells

Keegan D. Korthauer, G. Stephanopoulos, J. Kelleher, 2021, The FEBS journal.

Metabolic regulation of Akt: roles reversed

J. Rathmell, J. L. Coloff, Jonathan L. Coloff, 2006, The Journal of cell biology.

Cancer esearch apeutics , Targets , and Chemical Biology obic Glycolysis Suppresses p 53 Activity to Provide ctive Protection from Apoptosis upon Loss of R wth Signals or Inhibition of BCR-Abl

J. Rathmell, J. L. Coloff, F. Mason, 2010 .

Glutamate Dehydrogenase to the Rescue.

J. L. Coloff, 2018, Molecular cell.

Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy

G. Stephanopoulos, D. Sept, I. Harris, 2023, bioRxiv.