Yongbo Liu

发表

The inhibition of cell proliferation and induction of apoptosis in pancreatic ductal adenocarcinoma cells by verrucarin A, a macrocyclic trichothecene, is associated with the inhibition of Akt/NF-кB/mTOR prosurvival signaling.

D. Deeb, Xiaohua Gao, Yongbo Liu, 2016, International journal of oncology.

CDDO-Me inhibits tumor growth and prevents recurrence of pancreatic ductal adenocarcinoma

D. Deeb, Xiaohua Gao, Yongbo Liu, 2015, International journal of oncology.

Prevention of Prostate Cancer with Oleanane Synthetic Triterpenoid CDDO-Me in the TRAMP Mouse Model of Prostate Cancer

S. Dulchavsky, G. Divine, D. Deeb, 2011, Cancers.

Synthetic triterpenoid CDDO prevents the progression and metastasis of prostate cancer in TRAMP mice by inhibiting survival signaling.

S. Dulchavsky, G. Divine, D. Deeb, 2011, Carcinogenesis.

Synthetic triterpenoids inhibit growth and induce apoptosis in human glioblastoma and neuroblastoma cells through inhibition of prosurvival Akt, NF-κB and Notch1 signaling

S. Dulchavsky, Hao Jiang, D. Deeb, 2007, Journal of Neuro-Oncology.

RIP1 kinase activity-dependent roles in embryonic development of Fadd-deficient mice

Dali Li, Yongbo Liu, Qun Zhao, 2017, Cell Death and Differentiation.

Pooled CRISPR screening identifies m6A as a positive regulator of macrophage activation

R. Flavell, Yongbo Liu, Hua-Bing Li, 2021, Science Advances.

ROS mediate proapoptotic and antisurvival activity of oleanane triterpenoid CDDO-Me in ovarian cancer cells.

D. Deeb, Xiaohua Gao, Yongbo Liu, 2013, Anticancer research.

Synthetic oleanane triterpenoid, CDDO-Me, induces apoptosis in ovarian cancer cells by inhibiting prosurvival AKT/NF-κB/mTOR signaling.

S. Dulchavsky, D. Deeb, Xiaohua Gao, 2011, Anticancer research.

Immunomodulatory activity of curcumin: suppression of lymphocyte proliferation, development of cell-mediated cytotoxicity, and cytokine production in vitro.

S. Dulchavsky, Hao Jiang, G. Divine, 2004, Biochemical pharmacology.

Anticancer activity of pristimerin in ovarian carcinoma cells is mediated through the inhibition of prosurvival Akt/NF-κB/mTOR signaling.

D. Deeb, Xiaohua Gao, Yongbo Liu, 2014, Journal of experimental therapeutics & oncology.

Anticancer agent xanthohumol inhibits IL-2 induced signaling pathways involved in T cell proliferation.

S. Dulchavsky, D. Deeb, Xiaohua Gao, 2012, Journal of experimental therapeutics & oncology.

RIPK3 Mediates Necroptosis during Embryonic Development and Postnatal Inflammation in Fadd-Deficient Mice.

Yongbo Liu, Qun Zhao, Qun Xie, 2017, Cell reports.

MLKL and FADD Are Critical for Suppressing Progressive Lymphoproliferative Disease and Activating the NLRP3 Inflammasome.

Yongbo Liu, Qun Zhao, Qun Xie, 2016, Cell reports.

Gambogenic acid inhibits LPS-simulated inflammatory response by suppressing NF-κB and MAPK in macrophages.

Yongbo Liu, Qun Zhao, Qun Xie, 2016, Acta biochimica et biophysica Sinica.

Celastrol ameliorates inflammation through inhibition of NLRP3 inflammasome activation

Yongbo Liu, Qun Zhao, Xixi Zhang, 2017, Oncotarget.

Fragment-based identification of amides derived from trans-2-(pyridin-3-yl)cyclopropanecarboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).

Brandon J. Bravo, Qiang Zhao, N. Skelton, 2013, Journal of medicinal chemistry.

Synthetic triterpenoids inhibit growth, induce apoptosis and suppress pro-survival Akt, mTOR and NF-{kappa}B signaling proteins in colorectal cancer cells.

S. Dulchavsky, D. Deeb, Xiaohua Gao, 2010, Anticancer research.

Oleanane triterpenoid CDDO-Me inhibits Akt activity without affecting PDK1 kinase or PP2A phosphatase activity in cancer cells.

D. Deeb, Xiaohua Gao, Yongbo Liu, 2012, Biochemical and biophysical research communications.

Immunomodulatory Activity of Synthetic Triterpenoids: Inhibition of Lymphocyte Proliferation, Cell-Mediated Cytotoxicity, and Cytokine Gene Expression Through Suppression of NF-κB

S. Dulchavsky, D. Deeb, Xiaohua Gao, 2008, Immunopharmacology and immunotoxicology.

tRNA-m1A modification promotes T cell expansion via efficient MYC protein synthesis

R. Flavell, Xiaoyu Li, C. Yi, 2022, Nature Immunology.

Role of reactive oxygen species (ROS) in CDDO-Me-mediated growth inhibition and apoptosis in colorectal cancer cells.

S. Dulchavsky, D. Deeb, Xiaohua Gao, 2011, Journal of experimental therapeutics & oncology.

Ubiquitin-binding domain in ABIN1 is critical for regulating cell death and inflammation during development

Lin Qiu, Yongbo Liu, Qun Zhao, 2021, Cell Death & Differentiation.

cGAS activation in phased droplets

R. Flavell, Yongbo Liu, Hua-Bing Li, 2018, Cell Research.

Immunomodulatory activity of xanthohumol: inhibition of T cell proliferation, cell-mediated cytotoxicity and Th1 cytokine production through suppression of NF-κB

S. Dulchavsky, D. Deeb, Xiaohua Gao, 2009, Immunopharmacology and immunotoxicology.

Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase

Xukun Chen, Mark Zak, Yongbo Liu, 2014, Chembiochem : a European journal of chemical biology.

Inhibition of cell proliferation and induction of apoptosis by oleanane triterpenoid (CDDO-Me) in pancreatic cancer cells is associated with the suppression of hTERT gene expression and its telomerase activity.

D. Deeb, Xiaohua Gao, Yongbo Liu, 2012, Biochemical and biophysical research communications.

Discovery of a first-in-class CDK2 selective degrader for AML differentiation therapy

Qiaojun He, Bo Yang, Yongbo Liu, 2021, Nature Chemical Biology.

Induction of Apoptosis in Pancreatic Cancer Cells by CDDO-Me Involves Repression of Telomerase through Epigenetic Pathways

D. Deeb, Xiaohua Gao, Yongbo Liu, 2014, Journal of carcinogenesis & mutagenesis.

Inhibition of Telomerase Activity by Oleanane Triterpenoid CDDO-Me in Pancreatic Cancer Cells is ROS-Dependent

D. Deeb, Xiaohua Gao, Yongbo Liu, 2013, Molecules.

Telomerase Reverse Transcriptase (TERT) is a Therapeutic Target of Oleanane Triterpenoid CDDO-Me in Prostate Cancer

D. Deeb, Xiaohua Gao, Yongbo Liu, 2012, Molecules.

Celastrol ameliorates inflammation through inhibition of NLRP3 inflammasome activation

Yongbo Liu, Qun Zhao, Xixi Zhang, 2017, Oncotarget.

Wound repair by bone marrow stromal cells through growth factor production.

S. Dulchavsky, M. Chopp, Xiaohua Gao, 2006, The Journal of surgical research.

Inhibition of hTERT/telomerase contributes to the antitumor activity of pristimerin in pancreatic ductal adenocarcinoma cells

D. Deeb, Xiaohua Gao, Yongbo Liu, 2015, Oncology reports.

MLKL attenuates colon inflammation and colitis-tumorigenesis via suppression of inflammatory responses.

J. Qin, Yongbo Liu, Jing Fang, 2019, Cancer letters.

Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived ureas as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).

Yang Xiao, Lei Zhang, Deepak Sampath, 2013, Bioorganic & medicinal chemistry letters.

A novel sgRNA selection system for CRISPR-Cas9 in mammalian cells.

Yongbo Liu, Qun Zhao, Qun Xie, 2016, Biochemical and biophysical research communications.