D. Galson

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Developmental Aspects of Pagetic Osteoclasts

D. Galson, Quanhong Sun, G. Roodman, 2016 .

TBK1 Mediates Critical Effects of Measles Virus Nucleocapsid Protein (MVNP) on Pagetic Osteoclast Formation

D. Galson, Quanhong Sun, G. Roodman, 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Pathobiology of Paget's Disease of Bone

D. Galson, G. Roodman, 2014, Journal of bone metabolism.

Epigallocatechin-3-gallate diminishes CCL2 expression in human osteoblastic cells via up-regulation of phosphatidylinositol 3-Kinase/Akt/Raf-1 interaction: a potential therapeutic benefit for arthritis.

C. Hong, D. Galson, S. Kok, 2008, Arthritis and rheumatism.

The proto-oncogene PU.1 regulates expression of the myeloid-specific CD11b promoter.

R. Maki, D. Tenen, H. Pahl, 1993, The Journal of biological chemistry.

ATF4 promotes bone angiogenesis by increasing vegf expression and release in the bone environment

Hongli Jiao, H. Im, Di Chen, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Chapter 34 – Structure and Molecular Biology of the Calcitonin Receptor

D. Galson, S. Goldring, 2002 .

Phospholipase D- and protein kinase C isoenzyme-dependent signal transduction pathways activated by the calcitonin receptor.

D. Galson, S. Goldring, A. Teti, 1998, Endocrinology.

Osteoblast suppression in multiple myeloma bone disease

D. Galson, G. Roodman, Juraj Adamik, 2018, Journal of bone oncology.

Calcitonin-dependent down-regulation of the mouse C1a calcitonin receptor in cells of the osteoclast lineage involves a transcriptional mechanism.

R. Baron, W. Horne, D. Galson, 1999, Endocrinology.

Growth factor independence 1 expression in myeloma cells enhances their growth, survival, and osteoclastogenesis

K. Mohammad, D. Galson, Quanhong Sun, 2018, Journal of Hematology & Oncology.

C/EBPbeta regulates transcription factors critical for proliferation and survival of multiple myeloma cells.

B. Dörken, C. Milcarek, D. Galson, 2009, Blood.

Expression of the Transcription Factor, Spi-1 (PU.1), in Differentiating Murine Erythroleukemia Cells Is Regulated Post-transcriptionally

D. Galson, J. Hensold, C. A. Stratton, 1996, The Journal of Biological Chemistry.

A combined computational and experimental approach reveals the structure of a C/EBPβ–Spi1 interaction required for IL1B gene transcription

J. Madura, C. Camacho, D. Galson, 2018, The Journal of Biological Chemistry.

Erythropoietin gene regulation depends on heme-dependent oxygen sensing and assembly of interacting transcription factors.

D. Livingston, D. Krainc, L. Huang, 1997, Kidney international.

Cis Elements That Regulate the Erythropoietin Gene a

M. Goldberg, D. Galson, J. Fandrey, 1994, Annals of the New York Academy of Sciences.

EBP regulates transcription factors critical for proliferation and survival of multiple myeloma cells

B. Dörken, C. Milcarek, D. Galson, 2009 .

Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo

C. Laplace, G. Karsenty, D. Galson, 2004, The Journal of cell biology.

ADAM8 Enhances Osteoclast Precursor Fusion and Osteoclast Formation In Vitro and In Vivo

M. Subler, D. Galson, G. Roodman, 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Contributions of the measles virus nucleocapsid gene and the SQSTM1/p62(P392L) mutation to Paget's disease.

Jacques P. Brown, J. Morissette, D. Dempster, 2011, Cell metabolism.

Activating transcription factor 4 regulates osteoclast differentiation in mice.

D. Galson, G. Roodman, N. Kurihara, 2010, The Journal of clinical investigation.

Osteoclasts in Skeletal Diseases

D. Galson, Quanhong Sun, Juraj Adamik, 2020 .

EZH2 or HDAC1 Inhibition Reverses Multiple Myeloma–Induced Epigenetic Suppression of Osteoblast Differentiation

Shun-qian Jin, D. Galson, Quanhong Sun, 2017, Molecular Cancer Research.

CXCL16 Functions as a Novel Chemotactic Factor for Prostate Cancer Cells In vitro

Jianhua Wang, R. Taichman, D. Galson, 2008, Molecular Cancer Research.

CXCL 16 Functions as a Novel Chemotactic Factor for Prostate Cancer Cells In vitro

Jianhua Wang, R. Taichman, D. Galson, 2008 .

Monocyte expression of the human prointerleukin 1 beta gene (IL1B) is dependent on promoter sequences which bind the hematopoietic transcription factor Spi-1/PU.1

A. C. Webb, D. Galson, P. Auron, 1995, Molecular and cellular biology.

The human prointerleukin 1 beta gene requires DNA sequences both proximal and distal to the transcription start site for tissue-specific induction

A. C. Webb, D. Galson, M. Fenton, 1993, Molecular and cellular biology.

TheHumanProinterleukin 13GeneRequires DNA Sequences Both Proximal andDistal totheTranscription Start Sitefor Tissue-Specific Induction

A. C. Webb, D. Galson, M. Fenton, 1993 .

Resveratrol triggers the pro-apoptotic endoplasmic reticulum stress response and represses pro-survival XBP1 signaling in human multiple myeloma cells.

D. Galson, G. Roodman, Feng-ming Wang, 2011, Experimental hematology.

TRAF6 activation of PI 3-kinase-dependent cytoskeletal changes is cooperative with Ras and is mediated by an interaction with cytoplasmic Src

D. Galson, Chang-Deng Hu, P. Auron, 2006, Journal of Cell Science.

Detection of two tissue-specific DNA-binding proteins with affinity for sites in the mouse beta-globin intervening sequence 2

D. Housman, D. Galson, D. Housman, 1988, Molecular and cellular biology.

IMiD immunomodulatory compounds block C/EBP{beta} translation through eIF4E down-regulation resulting in inhibition of MM.

D. Galson, H. Ouyang, P. Schafer, 2011, Blood.

EZH2 Supports Osteoclast Differentiation and Bone Resorption Via Epigenetic and Cytoplasmic Targets

D. Galson, Quanhong Sun, P. Auron, 2020, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Immortalization of osteoclast precursors by targeting Bcl -XL and Simian virus 40 large T antigen to the osteoclast lineage in transgenic mice.

S. Reddy, D. Galson, N. Kurihara, 1998, The Journal of clinical investigation.

Gﬁ1 expressed in bone marrow stromal cells is a novel osteoblast suppressor in patients with multiple myeloma bone disease

Shun-qian Jin, H. Grimes, D. Galson, 2011 .

Activating transcription factor 4 is critical for proliferation and survival in primary bone marrow stromal cells and calvarial osteoblasts

D. Galson, Shibing Yu, Jie Fan, 2008, Journal of cellular biochemistry.

General Transcription Factor IIA-γ Increases Osteoblast-specific Osteocalcin Gene Expression via Activating Transcription Factor 4 and Runt-related Transcription Factor 2*

D. Galson, Shibing Yu, G. Xiao, 2008, Journal of Biological Chemistry.

TRAF6 is autoinhibited by an intramolecular interaction which is counteracted by trans‐ubiquitination

D. Galson, P. Auron, Kent Z. Q. Wang, 2010, Journal of cellular biochemistry.

The Role of Semaphorin 4D in Bone Remodeling and Cancer Metastasis

J. Chirgwin, D. Galson, A. Suvannasankha, 2018, Front. Endocrinol..

Role of ATF7‐TAF12 interactions in the vitamin D response hypersensitivity of osteoclast precursors in Paget's disease

Jacques P. Brown, D. Dempster, Hua Zhou, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Comparison of the human and mouse erythropoietin genes shows extensive homology in the flanking regions.

P. Ratcliffe, D. Galson, H. Bunn, 1993, Blood.

The orphan receptor hepatic nuclear factor 4 functions as a transcriptional activator for tissue-specific and hypoxia-specific erythropoietin gene expression and is antagonized by EAR3/COUP-TF1

T. Ogura, L. Huang, D. Galson, 1995, Molecular and cellular biology.

Nuclear Factor of Activated T-cells (NFAT) Rescues Osteoclastogenesis in Precursors Lacking c-Fos*

H. Aburatani, E. Wagner, C. Laplace, 2004, Journal of Biological Chemistry.

Kindlin-2 controls TGF-β signalling and Sox9 expression to regulate chondrogenesis

Hongli Jiao, H. Im, Di Chen, 2015, Nature Communications.

Molecular Mechanisms of TRAF6 Ubiquitination and Activation

D. Galson, P. Auron, Juraj Adamik, 2010 .

Tissue‐specific nuclear factors mediate expression of the CD3 delta gene during T cell development.

D. Galson, K. Georgopoulos, C. Terhorst, 1990, The EMBO journal.

Distinct Mechanisms for Induction and Tolerance Regulate the Immediate Early Genes Encoding Interleukin 1β and Tumor Necrosis Factor α

D. Galson, L. O’Neill, G. Tannahill, 2013, PloS one.

Phosphorylation of IRF8 in a pre-associated complex with Spi-1/PU.1 and non-phosphorylated Stat1 is critical for LPS induction of the IL1B gene.

Junichi Tsukada, D. Galson, P. Auron, 2007, Molecular immunology.

Dual regulatory role of human cytomegalovirus immediate-early protein in IL1B transcription is dependent upon Spi-1/PU.1.

D. Galson, Zhiyong Yang, P. Auron, 2002, Biochemical and biophysical research communications.

Mouse beta-globin DNA-binding protein B1 is identical to a proto-oncogene, the transcription factor Spi-1/PU.1, and is restricted in expression to hematopoietic cells and the testis

D. Housman, A. D’Andrea, D. Galson, 1993, Molecular and cellular biology.

Monocyte chemotactic protein‐1 (MCP‐1) acts as a paracrine and autocrine factor for prostate cancer growth and invasion

D. Galson, G. Xiao, Yi Lu, 2006, The Prostate.

Hypoxic induction of the human erythropoietin gene: cooperation between the promoter and enhancer, each of which contains steroid receptor response elements

D. Galson, H. Bunn, K. Blanchard, 1992, Molecular and cellular biology.

PTHrP‐induced MCP‐1 production by human bone marrow endothelial cells and osteoblasts promotes osteoclast differentiation and prostate cancer cell proliferation and invasion in vitro

D. Galson, G. Xiao, Yi Lu, 2007, International journal of cancer.

Epigenetic‐Based Mechanisms of Osteoblast Suppression in Multiple Myeloma Bone Disease

D. Galson, G. Roodman, G. David Roodman, 2019, JBMR plus.

Role of Sphingolipids in Multiple Myeloma Progression, Drug Resistance, and Their Potential as Therapeutic Targets

D. Galson, Kelvin P Lee, D. Petrusca, 2022, Frontiers in Oncology.

Origins of Osteoclasts

D. Galson, G. Roodman, 2011 .

Mechanisms of multiple myeloma bone disease.

D. Galson, G. Roodman, R. Silbermann, 2012, BoneKEy reports.

Specific transcription factors distinctly regulate kinetics of IL1B and TNF gene expression

D. Galson, P. Auron, Juraj Adamik, 2016 .

Increased IL‐6 Expression in Osteoclasts Is Necessary But Not Sufficient for the Development of Paget's Disease of Bone

Hua Zhou, M. Subler, D. Galson, 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Osteoclasts: Potential Target for Blocking Microenvironmental Support of Myeloma

D. Galson, G. Roodman, S. D'souza, 2013 .

XRK3F2 Inhibition of p62-ZZ Domain Signaling Rescues Myeloma-Induced GFI1-Driven Epigenetic Repression of the Runx2 Gene in Pre-osteoblasts to Overcome Differentiation Suppression

X. Xie, D. Galson, Quanhong Sun, 2018, Front. Endocrinol..

Gfi1 expressed in bone marrow stromal cells is a novel osteoblast suppressor in patients with multiple myeloma bone disease.

H. Grimes, D. Galson, B. Sammut, 2011, Blood.

The role of TNF-receptor family members and other TRAF-dependent receptors in bone resorption

D. Galson, S. Goldring, E. Gravallese, 2000, Arthritis research.

A Novel Sulforaphane-Regulated Gene Network in Suppression of Breast Cancer–Induced Osteolytic Bone Resorption

P. Kumta, Shivendra V. Singh, Boeun Lee, 2019, Molecular Cancer Therapeutics.

Oncostatin M-induced CCL2 transcription in osteoblastic cells is mediated by multiple levels of STAT-1 and STAT-3 signaling: an implication for the pathogenesis of arthritis.

C. Hong, D. Galson, S. Kok, 2009, Arthritis and rheumatism.