S. Coyle

发表

Insulin-Dependent Regulation of mTORC2-Akt-FoxO Suppresses TLR4 Signaling in Human Leukocytes: Relevance to Type 2 Diabetes

M. Birnbaum, Zhiyong Zhang, L. Amorosa, 2016, Diabetes.

Understanding Physiology in the Continuum: Integration of Information from Multiple -Omics Levels

I. Androulakis, D. DuBois, R. Almon, 2017, Front. Pharmacol..

Human toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of gram-negative infections.

S. Calvano, S. Lowry, S. Coyle, 2002, The Journal of infectious diseases.

RELATIONSHIP OF BASAL HEART RATE VARIABILITY TO IN VIVO CYTOKINE RESPONSES after endotoxin exposure

S. Calvano, S. Lowry, S. Coyle, 2010, Shock.

Influence of Acute Epinephrine Infusion on Endotoxin-Induced Parameters of Heart Rate Variability: A Randomized Controlled Trial

Shou-En Lu, S. Calvano, S. Lowry, 2009, Annals of surgery.

Effects of coupled dose and rhythm manipulation of plasma cortisol levels on leukocyte transcriptional response to endotoxin challenge in humans

I. Androulakis, S. Calvano, S. Coyle, 2014, Innate immunity.

Temporal Metabolic Profiling of Plasma During Endotoxemia in Humans

I. Androulakis, S. Calvano, S. Coyle, 2013, Shock.

Natural history of retained surgical items supports the need for team training, early recognition, and prompt retrieval.

S. Moffatt-Bruce, S. Coyle, S. Stawicki, 2014, American journal of surgery.

Down-regulation of surface receptors for TNF and IL-1 on circulating monocytes and granulocytes during human endotoxemia: effect of neutralization of endotoxin-induced TNF activity by infusion of a recombinant dimeric TNF receptor.

T. van der Poll, S. Lowry, S. Coyle, 1997, Journal of immunology.

Influence of hypercortisolemia on the acute-phase protein response to endotoxin in humans.

L. Moldawer, S. Lowry, S. Coyle, 1992, Surgery.

Antiinflammatory cytokine responses during clinical sepsis and experimental endotoxemia: sequential measurements of plasma soluble interleukin (IL)-1 receptor type II, IL-10, and IL-13.

T. van der Poll, S. Lowry, R. de Waal Malefyt, 1997, The Journal of infectious diseases.

Human metabolic response to systemic inflammation: assessment of the concordance between experimental endotoxemia and clinical cases of sepsis/SIRS

S. Kingsmore, I. Androulakis, S. Calvano, 2015, Critical Care.

Increased Healthcare-Associated Infections in a Surgical Intensive Care Unit Related to Boarding Non-Surgical Patients.

S. Coyle, M. Lissauer, Rajan Gupta, 2019, Surgical infections.

Influence of hypercortisolemia on soluble tumor necrosis factor receptor II and interleukin-1 receptor antagonist responses to endotoxin in human beings.

T. van der Poll, S. Lowry, A. Barber, 1995, Surgery.

Effect of Combined Cortisol-Endotoxin Administration on Peripheral Blood Leukocyte Counts and Phenotype in Cortisol-Endotoxin

S. Calvano, S. Lowry, A. Barber, 1992 .

Effect of hypertriglyceridemia on endotoxin responsiveness in humans

M. Boermeester, T. van der Poll, S. Calvano, 1995, Infection and immunity.

The influence of human endotoxemia on CD95-induced apoptosis.

S. Calvano, S. Lowry, S. Coyle, 1998, Archives of surgery.

Endotoxin induces downregulation of tumor necrosis factor receptors on circulating monocytes and granulocytes in humans.

T. van der Poll, S. Calvano, L. Moldawer, 1995, Blood.

Response to systemic endotoxemia among humans bearing polymorphisms of the Toll-like receptor 4 (hTLR4).

S. Calvano, S. Lowry, S. Coyle, 2006, Clinical immunology.

Expression of tumour necrosis factor receptor and Toll‐like receptor 2 and 4 on peripheral blood leucocytes of human volunteers after endotoxin challenge: a comparison of flow cytometric light scatter and immunofluorescence gating

S. Calvano, S. Lowry, S. Coyle, 2005, Clinical and experimental immunology.

Proteolytic Cleavage of AMPKa and Intracellular MMP9 Expression Are Both Required for TLR4-Mediated mTORC1 Activation and HIF-1a Expression in Leukocytes

L. Amorosa, S. Coyle, B. Haimovich, 2015 .

Interleukin-1 receptor blockade does not affect endotoxin-induced changes in plasma thyroid hormone and thyrotropin concentrations in man.

T. van der Poll, L. Moldawer, S. Lowry, 1995, The Journal of clinical endocrinology and metabolism.

Effect of a recombinant dimeric tumor necrosis factor receptor on inflammatory responses to intravenous endotoxin in normal humans.

T. van der Poll, J. T. ten Cate, S. Lowry, 1997, Blood.

Neutralization of TNF does not influence endotoxininduced changes in thyroid hormone metabolism in humans.

T. van der Poll, S. Lowry, S. Coyle, 1999, American Journal of Physiology.

Changes in polymorphonuclear leukocyte surface and plasma bactericidal/permeability-increasing protein and plasma lipopolysaccharide binding protein during endotoxemia or sepsis.

P. Barie, S. Calvano, L. Moldawer, 1994, Archives of surgery.

Influence of the TNF-α and TNF-β polymorphisms upon infectious risk and outcome in surgical intensive care patients

S. Calvano, S. Lowry, S. Coyle, 2003 .

Persistently elevated soluble tumor necrosis factor receptor and interleukin-1 receptor antagonist levels in critically ill patients.

P. Barie, L. Moldawer, S. Lowry, 1994, Journal of the American College of Surgeons.

Modulation of the Lipopolysaccharide Receptor Complex (CD14, TLR4, MD-2) and Toll-Like Receptor 2 in Systemic Inflammatory Response Syndrome-Positive Patients With and Without Infection: Relationship to Tolerance

S. Calvano, S. Lowry, S. Coyle, 2003, Shock.

Epinephrine attenuates down‐regulation of monocyte tumor necrosis factor receptors during human endotoxemia

S. Calvano, S. Lowry, S. Coyle, 1997, Journal of leukocyte biology.

Changes in endotoxin-induced cytokine production by whole blood after in vivo exposure of normal humans to endotoxin.

T. van der Poll, L. Moldawer, S. Lowry, 1996, The Journal of infectious diseases.

Epinephrine Exerts Anticoagulant Effects during Human Endotoxemia

T. van der Poll, S. Lowry, S. Coyle, 1997, The Journal of experimental medicine.

UvA-DARE (Digital Academic Repository) Epinephrine exerts anticoagulant effects during human endotoxemia

S. Lowry, S. Coyle, W. Buurman, 1997 .

Parenteral nutrition facilitates activation of coagulation but not of fibrinolysis during human endotoxemia.

T. van der Poll, J. T. ten Cate, S. Lowry, 1998, The Journal of infectious diseases.

Fat Emulsion Infusion Potentiates Coagulation Activation during Human Endotoxemia

M. Boermeester, T. van der Poll, S. Lowry, 1996, Thrombosis and Haemostasis.

Effect of Recombinant Human 66 Insulin-like Growth Factor I and Early Total Parenteral Nutrition on Immune Depression Following Severe Head Injury

Fowler, Stephen, L. Moldawer, 2012 .

Integrated Transcriptional and Metabolic Profiling in Human Endotoxemia

Kubra Kamisoglu, Ioannis P Androulakis, I. Androulakis, 2014, Shock.

A novel model of common Toll-like receptor 4- and injury-induced transcriptional themes in human leukocytes

S. Calvano, S. Lowry, S. Coyle, 2010, Critical care.

APOε4 is associated with enhanced in vivo innate immune responses in human subjects.

P. Blackshear, K. Barnes, M. Wurfel, 2014, The Journal of allergy and clinical immunology.

Recombinant Human Interleukin 1 Receptor Antagonist in the Treatment of Patients With Sepsis Syndrome: Results From a Randomized, Double-blind, Placebo-Controlled Trial

R. F. Johnston, Robert W. Taylor, Steven C. Johnson, 1994 .

A single nucleotide polymorphism in the Mdm2 promoter and risk of sepsis.

S. Calvano, S. Lowry, S. Coyle, 2009, American journal of surgery.

Continuous Enteral and Parenteral Feeding Each Reduces Heart Rate Variability But Differentially Influences Monocyte Gene Expression in Humans

Steve E. Calvano, Stephen F. Lowry, S. Calvano, 2012, Shock.

Total Parenteral Nutrition and Bowel Rest Modify the Metabolic Response to Endotoxin in Humans

L. Moldawer, S. Lowry, A. Barber, 1989, Annals of surgery.

Effects of Drotrecogin Alfa (Activated) in Human Endotoxemia

S. Calvano, S. Lowry, S. Coyle, 2004, Shock.

Interleukin-1 blockade attenuates mediator release and dysregulation of the hemostatic mechanism during human sepsis.

M. Boermeester, S. Lowry, C. Hack, 1995, Archives of surgery.

In vivo endotoxin synchronizes and suppresses clock gene expression in human peripheral blood leukocytes*

S. Calvano, S. Lowry, S. Coyle, 2010, Critical care medicine.

Effect of combined cortisol-endotoxin administration on peripheral blood leukocyte counts and phenotype in normal humans.

S. Calvano, S. Lowry, A. Barber, 1992, Archives of surgery.

Correlation between acute physiology and chronic health evaluation (APACHE) III score and immunological parameters in critically ill patients with sepsis

L. Moldawer, S. Lowry, H. Oldenburg, 1996, The British journal of surgery.

POLYMORPHISMS OF HEAT SHOCK PROTEIN-70 (HSPA1B AND HSPA1L LOCI) DO NOT INFLUENCE INFECTION OR OUTCOME RISK IN CRITICALLY ILL SURGICAL PATIENTS

S. Calvano, S. Lowry, S. Coyle, 2006, Shock.

Glucocorticoid therapy alters hormonal and cytokine responses to endotoxin in man.

S. Calvano, L. Moldawer, S. Lowry, 1993, Journal of immunology.

TLR4 counteracts BVRA signaling in human leukocytes via differential regulation of AMPK, mTORC1 and mTORC2

Zhiyong Zhang, L. Amorosa, S. Coyle, 2019, Scientific Reports.

Epinephrine inhibits tumor necrosis factor-alpha and potentiates interleukin 10 production during human endotoxemia.

T. van der Poll, S. Lowry, S. Coyle, 1996, The Journal of clinical investigation.

Proteolytic Cleavage of AMPKα and Intracellular MMP9 Expression Are Both Required for TLR4-Mediated mTORC1 Activation and HIF-1α Expression in Leukocytes

Jeffrey L Carson, M. Birnbaum, Zhiyong Zhang, 2015, The Journal of Immunology.

Cellular Metabolic Regulators: Novel Indicators of Low-Grade Inflammation in Humans

S. Calvano, S. Lowry, Zhiyong Zhang, 2014, Annals of surgery.

The metabolic effects of platelet-activating factor antagonism in endotoxemic man.

L. Moldawer, S. Lowry, S. Coyle, 1994, Archives of surgery.

Hypercortisolemia increases plasma interleukin-10 concentrations during human endotoxemia--a clinical research center study.

T. van der Poll, S. Lowry, A. Barber, 1996, The Journal of clinical endocrinology and metabolism.

Monocyte tumor necrosis factor receptor levels as a predictor of risk in human sepsis.

P. Barie, T. van der Poll, S. Calvano, 1996, Archives of surgery.

Physiologic Variability at the Verge of Systemic Inflammation: Multiscale Entropy of Heart Rate Variability Is Affected by Very Low Doses of Endotoxin

S. Calvano, S. Lowry, S. Coyle, 2015, Shock.

Experimental human endotoxemia: a model of the systemic inflammatory response syndrome?

S. Calvano, S. Coyle, 2012, Surgical infections.

Retained surgical items: a problem yet to be solved.

Liza Chan, Raffaele Marchigiani, James Cipolla, 2013, Journal of the American College of Surgeons.

Multivariate analysis of 9 disease-associated variables for outcome prediction in patients with sepsis.

P. Barie, S. Calvano, S. Lowry, 1998, Archives of surgery.

Voluntarily Produced Increases in Heart Rate Variability Modulate Autonomic Effects of Endotoxin Induced Systemic Inflammation: An Exploratory Study

Shou-En Lu, S. Calvano, S. Lowry, 2010, Applied psychophysiology and biofeedback.

Nicotine exposure alters in vivo human responses to endotoxin

S. Calvano, S. Lowry, S. Coyle, 2006, Clinical and experimental immunology.

Low-dose steroid alters in vivo endotoxin-induced systemic inflammation but does not influence autonomic dysfunction

Shou-En Lu, S. Calvano, S. Lowry, 2007, Journal of endotoxin research.

Interleukin-1 contributes to increased concentrations of soluble tumor necrosis factor receptor type I in sepsis.

P. Barie, T. van der Poll, L. Moldawer, 1995, The Journal of infectious diseases.

GENDER INFLUENCES IN VIVO HUMAN RESPONSES TO ENDOTOXIN

S. Calvano, S. Lowry, S. Coyle, 2006, Shock.

Leukocytes Expression in a Activation and HIF-1 Required for TLR4-Mediated mTORC1 Intracellular MMP9 Expression Are Both and a Proteolytic Cleavage of AMPK

Zhiyong Zhang, L. Amorosa, S. Coyle, 2015 .

RELATIONSHIP OFBASAL HEART RATE VARIABILITY TO IN VIVO CYTOKINE RESPONSES FOLLOWING ENDOTOXIN

S. Calvano, S. Lowry, S. Coyle, 2009 .

TLR4 counteracts BVRA signaling in human leukocytes via differential regulation of AMPK, mTORC1 and mTORC2

Zhiyong Zhang, L. Amorosa, S. Coyle, 2019, Scientific Reports.

Clinical administration of LPS endotoxin show changes in heart rate variability are detected prior to changes in temperature

J. Semmlow, S. Calvano, S. Lowry, 2014, 2014 40th Annual Northeast Bioengineering Conference (NEBEC).

Immune deficiencies, infection, and systemic immune disordersAPOε4 is associated with enhanced in vivo innate immune responses in human subjects

P. Blackshear, K. Barnes, M. Wurfel, 2014 .

Influence of IL-1 receptor blockade on the human response to endotoxemia.

S. Calvano, L. Moldawer, S. Lowry, 1995, Journal of immunology.

Influence of the TNF-alpha and TNF-beta polymorphisms upon infectious risk and outcome in surgical intensive care patients.

S. Calvano, S. Lowry, S. Coyle, 2003, Surgical infections.

Instantaneous frequency analysis shows greater sensitivity to parasympathetic components of heart rate than spectral analysis

J. Semmlow, S. Calvano, S. Lowry, 2013, 2013 IEEE Signal Processing in Medicine and Biology Symposium (SPMB).

Outcomes among trauma patients with duodenal leak following primary versus complex repair of duodenal injuries: An Eastern Association for the Surgery of Trauma multicenter trial

Lisa M. Kodadek, Evan G. Wong, M. Narayan, 2023, The journal of trauma and acute care surgery.

Circulating cytokine antagonists in endotoxemia and sepsis

L. Hydo, P. Barie, L. Moldawer, 1993 .

Parenteral nutrition alters monocyte TNF receptor activity.

T. van der Poll, S. Calvano, S. Lowry, 1995, The Journal of surgical research.