K. Nishida

发表

Macromolecular Degradation Systems and Cardiovascular Aging.

Kinya Otsu, K. Otsu, H. Nakayama, 2016, Circulation research.

Mitochondrial DNA That Escapes from Autophagy Causes Inflammation and Heart Failure

S. Akira, I. Komuro, K. Otsu, 2012, Nature.

Degradation systems in heart failure.

K. Otsu, K. Nishida, O. Yamaguchi, 2015, Journal of molecular and cellular cardiology.

Autophagy during cardiac remodeling.

K. Otsu, K. Nishida, 2016, Journal of molecular and cellular cardiology.

Crosstalk Between Autophagy and Apoptosis in Heart Disease

K. Otsu, K. Nishida, O. Yamaguchi, 2008, Circulation research.

Sterile Inflammation and Degradation Systems in Heart Failure.

K. Otsu, K. Nishida, 2017, Circulation journal : official journal of the Japanese Circulation Society.

The role of apoptosis signal-regulating kinase 1 in cardiomyocyte apoptosis.

K. Otsu, K. Nishida, 2006, Antioxidants & redox signaling.

Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis.

J. Miyazaki, M. Hori, M. Taniike, 2004, The Journal of clinical investigation.

Title Cardiac-specific disruption of the c-raf-1 geneinduces cardiac dysfunction and apoptosis

J. Miyazaki, M. Hori, M. Taniike, 2022 .

Disruption of a single copy of the p38alpha MAP kinase gene leads to cardioprotection against ischemia-reperfusion.

M. Hori, K. Otsu, S. Hikoso, 2003, Biochemical and biophysical research communications.

Involvement of Nuclear Factor-&kgr;B and Apoptosis Signal-Regulating Kinase 1 in G-Protein–Coupled Receptor Agonist–Induced Cardiomyocyte Hypertrophy

Yasushi Matsumura, Takashi Morita, Masatsugu Hori, 2002, Circulation.

Activation of MTK1/MEKK4 induces cardiomyocyte death and heart failure.

I. Komuro, M. Hori, K. Otsu, 2010, Journal of molecular and cellular cardiology.

The I&kgr;B Kinase β/Nuclear Factor &kgr;B Signaling Pathway Protects the Heart From Hemodynamic Stress Mediated by the Regulation of Manganese Superoxide Dismutase Expression

M. Kogo, Keiichiro Suzuki, M. Hori, 2009, Circulation research.

Downregulation of ferritin heavy chain increases labile iron pool, oxidative stress and cell death in cardiomyocytes.

M. Hori, K. Otsu, Isamu Mizote, 2008, Journal of molecular and cellular cardiology.

Progression of heart failure was suppressed by inhibition of apoptosis signal-regulating kinase 1 via transcoronary gene transfer.

M. Hori, K. Otsu, M. Matsuzaki, 2007, Journal of the American College of Cardiology.

The Antioxidant Edaravone Attenuates Pressure Overload–Induced Left Ventricular Hypertrophy

M. Kogo, M. Hori, M. Taniike, 2005, Hypertension.

CaMKII activates ASK1 and NF-κB to induce cardiomyocyte hypertrophy

M. Hori, M. Taniike, K. Otsu, 2005 .

Pressure Overload Induces Cardiac Dysfunction and Dilation in Signal Transducer and Activator of Transcription 6-Deficient Mice

S. Akira, M. Hori, M. Taniike, 2004, Circulation.

Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling

M. Hori, M. Taniike, K. Otsu, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Thyroid hormone enhances Ca2+ pumping activity of the cardiac sarcoplasmic reticulum by increasing Ca2+ ATPase and decreasing phospholamban expression.

K. Otsu, K. Nishida, T. Kuzuya, 1994, Journal of molecular and cellular cardiology.

Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation

A. Shah, K. Otsu, S. Hikoso, 2015, Nature Communications.

[Preangina and plasma radical scavenger activity limit the size of infarct in patients with successful thrombolysis].

K. Nishida, K. Kodama, M. Mishima, 1993, Japanese circulation journal.

The role of autophagic degradation in the heart.

K. Otsu, K. Nishida, Manabu Taneike, 2015, Journal of molecular and cellular cardiology.

Autophagy-mediated degradation is necessary for regression of cardiac hypertrophy during ventricular unloading.

A. Shah, K. Otsu, S. Hikoso, 2013, Biochemical and biophysical research communications.

The antioxidant N-2-mercaptopropionyl glycine attenuates left ventricular hypertrophy in in vivo murine pressure-overload model.

M. Hori, K. Otsu, K. Nishida, 2002, Journal of the American College of Cardiology.

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

Yasushi Matsumura, Atsuko Nakai, Masatsugu Hori, 2007, Nature Medicine.

FKBP8 protects the heart from hemodynamic stress by preventing the accumulation of misfolded proteins and endoplasmic reticulum-associated apoptosis in mice

A. Shah, K. Otsu, T. Misaka, 2018, Journal of molecular and cellular cardiology.

Inflammation and metabolic cardiomyopathy.

K. Otsu, K. Nishida, 2017, Cardiovascular research.

mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy

A. Shah, K. Otsu, M. Gambello, 2016, PloS one.

Toll-like receptor 9 prevents cardiac rupture after myocardial infarction in mice independently of inflammation.

S. Akira, A. Shah, K. Otsu, 2016, American journal of physiology. Heart and circulatory physiology.

Rheb (Ras Homologue Enriched in Brain)-dependent Mammalian Target of Rapamycin Complex 1 (mTORC1) Activation Becomes Indispensable for Cardiac Hypertrophic Growth after Early Postnatal Period*

N. Sonenberg, A. Shah, I. Komuro, 2013, The Journal of Biological Chemistry.

Calpain Protects the Heart from Hemodynamic Stress*

I. Komuro, K. Otsu, N. Mochizuki, 2011, The Journal of Biological Chemistry.

Cell death in heart failure.

K. Otsu, K. Nishida, 2008, Circulation journal : official journal of the Japanese Circulation Society.

Involvement of reactive oxygen species-mediated NF-kappa B activation in TNF-alpha-induced cardiomyocyte hypertrophy.

M. Hori, K. Otsu, H. Ueno, 2002, Journal of molecular and cellular cardiology.

Effect of successful angioplasty following thrombolysis on infarct size and left ventricular function.

K. Nishida, M. Inoue, S. Nanto, 1994, International journal of cardiology.

Involvement of reactive oxygen species-mediated NF-kappa B activation in TNF-alpha-induced cardiomyocyte hypertrophy.

M. Hori, K. Otsu, H. Ueno, 2002, Journal of molecular and cellular cardiology.

Cytokine mRNA Degradation in Cardiomyocytes Restrains Sterile Inflammation in Pressure-Overloaded Hearts

S. Akira, A. Shah, K. Otsu, 2020, Circulation.

Toll-like receptor signaling: defensive or offensive for the heart?

M. Hori, K. Nishida, 2008, Circulation research.

Role of Neph2 in pontine nuclei formation in the developing hindbrain

F. Murakami, K. Nishida, Kazuhide Nakayama, 2011, Molecular and Cellular Neuroscience.

The I (cid:1) B Kinase (cid:2) /Nuclear Factor (cid:1) B Signaling Pathway Protects the Heart From Hemodynamic Stress Mediated by the Regulation of Manganese Superoxide Dismutase Expression

M. Kogo, Keiichiro Suzuki, M. Hori, 2009 .

Insulin-dependent formation of a complex containing an 85-kDa subunit of phosphatidylinositol 3-kinase and tyrosine-phosphorylated insulin receptor substrate 1.

M. Kasuga, I. Gout, M. Waterfield, 1992, The Journal of biological chemistry.

Ablation of Toll-like receptor 9 attenuates myocardial ischemia/reperfusion injury in mice

S. Akira, K. Otsu, Y. Sakata, 2019, Biochemical and biophysical research communications.

Expression of hOvol2 in the XY body of human spermatocytes

T. Matsuda, K. Nishida, S. Ito, 2017, Andrologia.

Apoptosis signal-regulating kinase 1 is involved not only in apoptosis but also in non-apoptotic cardiomyocyte death.

M. Hori, M. Taniike, K. Otsu, 2005, Biochemical and biophysical research communications.

Impact of coronary risk factors on contribution of nitric oxide and adenosine to metabolic coronary vasodilation in humans.

M. Hori, K. Nishida, H. Sato, 1998, Journal of the American College of Cardiology.

Supported angioplasty with synchronized retroperfusion in high-risk patients with left main trunk or near left main trunk obstruction.

K. Nishida, K. Kodama, S. Nanto, 1993, American heart journal.

Iron derived from autophagy-mediated ferritin degradation induces cardiomyocyte death and heart failure in mice

A. Shah, K. Otsu, Jumpei Ito, 2021, eLife.

Ptf1a Directly Controls Expression of Immunoglobulin Superfamily Molecules Nephrin and Neph3 in the Developing Central Nervous System*

F. Murakami, M. Hoshino, K. Nishida, 2009, The Journal of Biological Chemistry.

Classic cadherins regulate tangential migration of precerebellar neurons in the caudal hindbrain

H. Taniguchi, F. Murakami, D. Kawauchi, 2006, Development.

[Prevention of left ventricular dilation without infarct size limitation by late reperfusion in patients with acute myocardial infarction].

K. Nishida, K. Kodama, A. Hirayama, 1992, Japanese circulation journal.

Reduction in hemoglobin-oxygen affinity results in the improvement of exercise capacity in mice with chronic heart failure.

M. Hori, M. Taniike, K. Otsu, 2008, Journal of the American College of Cardiology.

Inhibition of autophagy in the heart induces age-related cardiomyopathy

I. Komuro, M. Hori, K. Otsu, 2010, Autophagy.

Receptor-mediated mitophagy.

K. Otsu, K. Nishida, O. Yamaguchi, 2016, Journal of molecular and cellular cardiology.

Anti-apoptotic function of Rac in hematopoietic cells

K. Nishida, Y. Kaziro, T. Satoh, 1999, Oncogene.

Tyrosine phosphorylation of ACK in response to temperature shift‐down, hyperosmotic shock, and epidermal growth factor stimulation

K. Nishida, Y. Kaziro, T. Satoh, 1996, FEBS letters.

Involvement of Brn3a-positive spinal dorsal horn neurons in the transmission of visceral pain in inflammatory bowel disease model mice

K. Nishida, S. Matsumura, Takuya Kobayashi, 2021, bioRxiv.

Autophagy in the Cardiovascular System

K. Otsu, K. Nishida, O. Yamaguchi, 2013 .

Oxidative stress and left ventricular remodelling after myocardial infarction.

M. Hori, K. Nishida, 2008, Cardiovascular research.

Apoptosis Signal-Regulating Kinase 1/p38 Signaling Pathway Negatively Regulates Physiological Hypertrophy

M. Hori, M. Taniike, K. Otsu, 2008, Circulation.

Presenilin 2 regulates the systolic function of heart by modulating Ca2+ signaling

M. Hori, T. Iwatsubo, M. Taniike, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Mitogen-Activated Protein Kinase Plays a Critical Role in Cardiomyocyte Survival but Not in Cardiac Hypertrophic Growth in Response to Pressure Overload

J. Miyazaki, M. Hori, M. Taniike, 2004 .

Elucidation of the mechanism of suppressed steroidogenesis during androgen deprivation therapy of prostate cancer patients using a mouse model

T. Matsuda, H. Kinoshita, K. Nishida, 2016, Andrology.

The point mutation Arg615-->Cys in the Ca2+ release channel of skeletal sarcoplasmic reticulum is responsible for hypersensitivity to caffeine and halothane in malignant hyperthermia.

M. Hori, K. Otsu, T. Kamada, 1994, The Journal of biological chemistry.

Single-strand conformation polymorphism analysis on the delta-sarcoglycan gene in Japanese patients with hypertrophic cardiomyopathy.

Y. Hayashizaki, M. Hori, K. Otsu, 2000, The American journal of cardiology.

The Small GTP-binding Protein Rac1 Induces Cardiac Myocyte Hypertrophy through the Activation of Apoptosis Signal-regulating Kinase 1 and Nuclear Factor-κB*

M. Hori, K. Otsu, H. Ueno, 2003, Journal of Biological Chemistry.

Association of the proto‐oncogene product Dbl with G protein βγ subunits

K. Nishida, Y. Kaziro, T. Satoh, 1999 .

Cardiac‐specific overexpression of a high Ca2+ affinity mutant of SERCA2a attenuates in vivo pressure overload cardiac hypertrophy

M. Hori, K. Otsu, S. Hikoso, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Developmental origin of long‐range neurons in the superficial dorsal spinal cord

K. Nishida, S. Ito, 2017, The European journal of neuroscience.

Three-Dimensional Distribution of Sensory Stimulation-Evoked Neuronal Activity of Spinal Dorsal Horn Neurons Analyzed by In Vivo Calcium Imaging

K. Nishida, S. Matsumura, S. Ito, 2014, PloS one.

Crucial roles of Robo proteins in midline crossing of cerebellofugal axons and lack of their up-regulation after midline crossing

F. Murakami, Yan Zhu, Y. Tanabe, 2008, Neural Development.

Ca(2+)-sensitive tyrosine kinase Pyk2/CAK beta-dependent signaling is essential for G-protein-coupled receptor agonist-induced hypertrophy.

M. Hori, M. Taniike, K. Otsu, 2004, Journal of molecular and cellular cardiology.

Association of the proto-oncogene product dbl with G protein betagamma subunits.

K. Nishida, Y. Kaziro, T. Satoh, 1999, FEBS letters.

In vivo two‐photon imaging of structural dynamics in the spinal dorsal horn in an inflammatory pain model

K. Nishida, S. Matsumura, S. Ito, 2015, The European journal of neuroscience.

Cloning and characterization of the 5'-upstream regulatory region of the Ca(2+)-release channel gene of cardiac sarcoplasmic reticulum.

M. Hori, K. Otsu, K. Nishida, 1996, European journal of biochemistry.

Domain-specific olivocerebellar projection regulated by the EphA-ephrin-A interaction

John G Flanagan, J. Flanagan, K. Nishida, 2002, Development.

CaMKII activates ASK1 and NF-kappaB to induce cardiomyocyte hypertrophy.

M. Hori, M. Taniike, K. Otsu, 2005, Biochemical and biophysical research communications.

Involvement of Brain-Enriched Guanylate Kinase-Associated Protein (BEGAIN) in Chronic Pain after Peripheral Nerve Injury

Masahiko Watanabe, Y. Hata, K. Sakimura, 2016, eNeuro.

Lysophosphatidylserine induces necrosis in pressure overloaded male mouse hearts via G protein coupled receptor 34

K. Otsu, Y. Sakata, K. Nishida, 2023, Nature communications.

The role of autophagy in the heart

K. Otsu, K. Nishida, J. Sadoshima, 2009, Cell Death and Differentiation.

p38α Mitogen-Activated Protein Kinase Plays a Critical Role in Cardiomyocyte Survival but Not in Cardiac Hypertrophic Growth in Response to Pressure Overload

J. Miyazaki, M. Hori, M. Taniike, 2004, Molecular and Cellular Biology.

Cardiac-Specific Disruption of Raf-1 Gene Induces Apoptosis and Cardiac Dysfunction

M. Hori, K. Otsu, H. Nakayama, 2003 .

Brn3a controls the soma localization and axonal extension patterns of developing spinal dorsal horn neurons

T. Badea, K. Nishida, S. Matsumura, 2023, bioRxiv.

The small GTP-binding protein Rac1 induces cardiac myocyte hypertrophy through the activation of apoptosis signal-regulating kinase 1 and nuclear factor-kappa B.

M. Hori, K. Otsu, H. Ueno, 2003, The Journal of biological chemistry.

Toll-like receptor 9 prevents cardiac rupture after myocardial infarction in mice independently of inflammation.

S. Akira, A. Shah, K. Otsu, 2016, American Journal of Physiology. Heart and Circulatory Physiology.