Shashank K Singh

发表

Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer.

Shakir Ali, A. Qazi, A. Hussain, 2015, Cancer letters.

Penicillium spp.: prolific producer for harnessing cytotoxic secondary metabolites

Shashank K Singh, Mytre Koul, Shashank K. Singh, 2017, Anti-cancer drugs.

Modulation of glycolysis and lipogenesis by novel PI3K selective molecule represses tumor angiogenesis and decreases colorectal cancer growth.

Shashi Bhushan, Santosh Kumar Guru, P. R. Sharma, 2016, Cancer letters.

Interaction of natural products with cell survival and signaling pathways in the biochemical elucidation of drug targets in cancer.

A. Qazi, A. Hussain, Shashank K Singh, 2011, Future oncology.

Development and characterization of hyaluronic acid modified PLGA based nanoparticles for improved efficacy of cisplatin in solid tumor.

P. R. Sharma, Shashank K Singh, D. Mondhe, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Oncogenic BRAF, endoplasmic reticulum stress, and autophagy: Crosstalk and therapeutic targets in cutaneous melanoma.

Shashank K Singh, M. Bhagat, Rafiq A. Rather, 2020, Mutation research.

4-aryl/heteroaryl-4H-fused Pyrans as Anti-proliferative Agents: Design, Synthesis and Biological Evaluation.

Dinesh Kumar, Shashank K Singh, D. Mondhe, 2018, Anti-cancer agents in medicinal chemistry.

Development and evaluation of paclitaxel loaded PLGA:poloxamer blend nanoparticles for cancer chemotherapy.

S. Jain, Shashank K Singh, A. Saneja, 2014, International journal of biological macromolecules.

Acyl derivatives of boswellic acids as inhibitors of NF-κB and STATs.

Shashank K Singh, S. C. Taneja, B. A. Shah, 2012, Bioorganic & medicinal chemistry letters.

Synthesis, characterization and mechanistic-insight into the anti-proliferative potential of PLGA-gemcitabine conjugate.

Shashank K Singh, A. Saxena, Deepika Singh, 2014, International journal of pharmaceutics.

In silico evaluation of the resistance of the T790M variant of epidermal growth factor receptor kinase to cancer drug Erlotinib

V. Uversky, Shashank K Singh, I. Singh, 2018, Journal of biomolecular structure & dynamics.

Synthesis of 1,2,4-oxadiazole derivatives: anticancer and 3D QSAR studies

Shashank K Singh, Shweta Jain, Ankur Vaidya, 2020, Monatshefte für Chemie - Chemical Monthly.

Genotoxicity and immunotoxic effects of 1,2-dichloroethane in Wistar rats

A. Hussain, Shashank K Singh, W. Ahmad, 2016, Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews.

Design and synthesis of spiro derivatives of parthenin as novel anti-cancer agents.

Shashank K Singh, S. C. Taneja, A. Saxena, 2011, European journal of medicinal chemistry.

An investigation of in vitro cytotoxicity and apoptotic potential of aromatic diselenides.

S. Bhushan, Shashank K Singh, B. A. Shah, 2014, Bioorganic & medicinal chemistry letters.

Development and evaluation of folate functionalized albumin nanoparticles for targeted delivery of gemcitabine.

P. R. Sharma, Shashank K Singh, D. Mondhe, 2015, International journal of pharmaceutics.

Immunostimulatory activity of plumieride an iridoid in augmenting immune system by targeting Th‐1 pathway in balb/c mice

Shashank K Singh, A. Hamid, N. Satti, 2017, International immunopharmacology.

Synthesis of 3-N-/O-/S-methyl-imidazo[1,2-a] pyridine derivatives for caspase-3 mediated apoptosis induced anticancer activity.

Shashank K Singh, A. Nargotra, A. Samykutty, 2022, Bioorganic chemistry.

Effect of acetyl 11-keto beta-boswellic acid on metastatic growth factor responsible for angiogenesis.

Shashank K Singh, A. Saxena, D. Mondhe, 2007, Vascular pharmacology.

Pre-clinical and cellular toxicity evaluation of 7-methylxanthine: an investigational drug for the treatment of myopia

Shashank K Singh, S. Jain, Harjeet Singh, 2019, Drug and chemical toxicology.

PLGA nanoparticles augmented the anticancer potential of pentacyclic triterpenediol in vivo in mice

Shashank K Singh, D. Mondhe, Amit Kumar, 2016 .

Secondary Metabolites from Endophytic Fungus Penicillium pinophilum Induce ROS-Mediated Apoptosis through Mitochondrial Pathway in Pancreatic Cancer Cells

P. R. Sharma, Ashok Kumar, A. Chaubey, 2016, Planta Medica.

Isolation, identification and bioactive potential of bacterial endophytes from Coleus

A. Chaubey, Shashank K Singh, Sumit G. Gandhi, 2019 .

Synthesis of β-boswellic acid derivatives as cytotoxic and apoptotic agents.

P. R. Sharma, Shashank K Singh, B. A. Shah, 2016, Bioorganic & medicinal chemistry letters.

Dendrimer encapsulated and conjugated delivery of berberine: A novel approach mitigating toxicity and improving in vivo pharmacokinetics.

M. P. Khinchi, Shashank K Singh, U. Gupta, 2017, International journal of pharmaceutics.

Isolation, Anticancer Evaluation, Molecular Docking, Drug likeness and ADMET Studies of Secondary Metabolites from Psoralea corylifolia seeds

Shashank K Singh, P. Sangwan, A. Qayum, 2022, ChemistrySelect.

T- and B-cell immunosuppressive activity of novel α-santonin analogs with humoral and cellular immune response in Balb/c mice.

Shashank K Singh, P. Sangwan, Nidhi Gupta, 2017, MedChemComm.

PARP cleavage and perturbance in mitochondrial membrane potential by 3-α-propionyloxy-β-boswellic acid results in cancer cell death and tumor regression in murine models.

P. R. Sharma, Shashank K Singh, S. C. Taneja, 2012, Future oncology.

Synthesis of 14-deoxy-benzylidene-8,17-epoxy-diene-andrographolide derivatives and evaluation of their anticancer activities

Shashank K Singh, S. Kaul, M. Dhar, 2022, Journal of the Indian Chemical Society.

Design and synthesis of highly oxygenated furo[3,2‐c]pyran‐4‐ones and furo[3,2‐c]chromen‐4‐ones scaffold as anticancer and antimicrobial agents

Shashank K Singh, P. Sangwan, Devinder Kumar, 2021, Journal of Heterocyclic Chemistry.

Synthesis, Biological Activity and Molecular Docking Studies of Heterocyclic Chalcones

Shashank K Singh, P. Sangwan, Devinder Kumar, 2022, Chemistry & biodiversity.

Synthesis, antiproliferative and apoptosis-inducing activity of thiazolo[5,4-d]pyrimidines.

P. R. Sharma, S. Bhushan, Shashank K Singh, 2013, European journal of medicinal chemistry.

Design, synthesis and anticancer activity of Michael-type thiol adducts of α-santonin analogue with exocyclic methylene.

Shashank K Singh, R. Vishwakarma, L. Pilcher, 2015, European journal of medicinal chemistry.

6-Nitro-2-(3-hydroxypropyl)-1H-benz[de]isoquinoline-1,3-dione, a potent antitumor agent, induces cell cycle arrest and apoptosis

P. R. Sharma, Shashank K Singh, A. Saxena, 2010, Journal of experimental & clinical cancer research : CR.

Naphthoflavones as Antiproliferative Agents: Design, Synthesis and Biological Evaluation.

Dinesh Kumar, Onkar Singh, Shashank K Singh, 2016, Anti-cancer agents in medicinal chemistry.

Synthesis of 4β-N-polyaromatic substituted podophyllotoxins: DNA topoisomerase inhibition, anticancer and apoptosis-inducing activities.

Shashank K Singh, A. Kamal, S. Agrawal, 2010, Bioorganic & medicinal chemistry.

Serine‐glycine‐betaine, a novel dipeptide from an endophyte Macrophomina phaseolina: isolation, bioactivity and biosynthesis

Shashank K Singh, V. Singamaneni, M. Katoch, 2021, Journal of applied microbiology.

LC–PDA–MS/MS-Based Dereplication Guided Isolation of a New Optical Isomer of 19,20-Epoxycytochalasin-N and Its Cytotoxic Activity

N. Sharma, Shashank K Singh, R. Vishwakarma, 2022, ACS omega.

Cladosporol A triggers apoptosis sensitivity by ROS-mediated autophagic flux in human breast cancer cells

P. R. Sharma, Ashok Kumar, Shashank K Singh, 2017, BMC Cell Biology.

Anticancer efficacy of methanolic extracts of some medicinal plants from Jammu region, Jammu & Kashmir, India

Shashank K Singh, Vikas Sharma, Navneet Kour, 2016 .

In vitro cytotoxic potential of Polyalthia longifolia on human cancer cell lines and induction of apoptosis through mitochondrial-dependent pathway in HL-60 cells.

S. Bhushan, Shashank K Singh, A. Saxena, 2008, Chemico-biological interactions.

Potential role of natural molecules in health and disease: importance of boswellic acid.

Shashank K Singh, A. Saxena, A. Hamid, 2010 .

In vitro anti cancer activity of ethanol extract fractions of Aerva lanata L.

Shashank K Singh, Rohini Sharma, M. Noolvi, 2013, Pakistan journal of biological sciences : PJBS.

Anticancer Activity of Cordia dichotoma against a Panel of Human Cancer Cell Lines and Their Phytochemical Profiling via HPLC and GCMS

Talal A. Zari, Shashank K Singh, Vikas Sharma, 2022, Molecules.

A new clerodane furano diterpene glycoside from Tinospora cordifolia triggers autophagy and apoptosis in HCT-116 colon cancer cells.

Ashok Kumar, Shashank K Singh, R. Vishwakarma, 2018, Journal of ethnopharmacology.

Isolation, Cytotoxicity Evaluation, Docking, ADMET and Drug Likeness Studies of Secondary Metabolites from the Stem Bark of Anthocephalus cadamba (Roxb.)

Shashank K Singh, P. Sangwan, A. Qayum, 2022, ChemistrySelect.

Synthesis and biological evaluation of novel bavachinin analogs as anticancer agents.

A. Raina, Shashank K Singh, P. Sangwan, 2018, European journal of medicinal chemistry.

A propionyloxy derivative of 11-keto-β-boswellic acid induces apoptosis in HL-60 cells mediated through topoisomerase I & II inhibition.

Shashank K Singh, S. C. Taneja, B. A. Shah, 2011, Chemico-biological interactions.

Synthesis of novel benzylidene analogues of betulinic acid as potent cytotoxic agents.

Shashank K Singh, P. Sangwan, S. Rath, 2017, European journal of medicinal chemistry.

A convergent synthesis of novel alkyne–azide cycloaddition congeners of betulinic acid as potent cytotoxic agent

Shashank K Singh, S. Rath, P. Sangwan, 2017, Steroids.

Thermosensitive injectable hydrogel containing carboplatin loaded nanoparticles: A dual approach for sustained and localized delivery with improved safety and therapeutic efficacy

Shashank K Singh, S. Jain, Anuradha Sharma, 2020 .

Karonda and Jamun seeds’ in vitro anticancer efficacy

Shashank K Singh, Akash Sharma, Vikas Sharma, 2019 .

Recent development in targeting PI3K-Akt-mTOR signaling for anticancer therapeutic strategies.

Shakir Ali, A. Qazi, A. Hussain, 2013, Anti-cancer agents in medicinal chemistry.

Discovery of a Secalonic Acid Derivative from Aspergillus aculeatus, an Endophyte of Rosa damascena Mill., Triggers Apoptosis in MDA-MB-231 Triple Negative Breast Cancer Cells

G. Bifulco, A. Chaubey, Shashank K Singh, 2020, ACS omega.

Holistic Molecular Approaches for Anticancer Therapy

Shashank K Singh, A. Saxena, G. Chashoo, 2012 .

A novel PI3K axis selective molecule exhibits potent tumor inhibition in colorectal carcinogenesis

Ashok Kumar, A. Qazi, A. Hussain, 2016, Molecular carcinogenesis.

Improved efficacy of cisplatin in combination with a nano-formulation of pentacyclic triterpenediol.

Shashank K Singh, Ashok Kumar, N. Alam, 2016, Materials science & engineering. C, Materials for biological applications.

Reduced toxicological manifestations of cisplatin following encapsulation in folate grafted albumin nanoparticles.

Shashank K Singh, Ashok Kumar, R. Dubey, 2015, Life sciences.

Induction of Mitochondrial-Dependent Apoptosis by an Essential Oil from Tanacetum gracile

M. K. Koul, S. Bhushan, Shashank K Singh, 2008, Planta medica.

Isolation of isoxanthanol and synthesis of novel derivatives as potential cytotoxic agents

Shashank K Singh, S. Koul, P. Sangwan, 2017, Medicinal Chemistry Research.

Transferrin-appended PEGylated nanoparticles for temozolomide delivery to brain: in vitro characterisation

Shashank K Singh, A. Saxena, Sanjay K. Jain, 2011, Journal of microencapsulation.

Development of biocompatible nanoparticles of tizanidine hydrochloride in orodispersible films: In vitro characterization, ex vivo permeation and cytotoxic study on carcinoma cells.

Shashank K Singh, M. Rahman, P. Pandey, 2022, Current drug delivery.

Therapeutic Targeting of Cancer Cell Metabolism: Role of Metabolic Enzymes, Oncogenes and Tumor Suppressor Genes

A. Qazi, A. Hussain, Shashank K Singh, 2012 .

Site-Selective Synthesis of C-17 Ester Derivatives of Natural Andrographolide for Evaluation as a Potential Anticancer Agent

Shashank K Singh, Davinder Singh, R. Shankar, 2023, ACS omega.

Chemically standardized isolates from Cedrus deodara stem wood having anticancer activity.

Shashank K Singh, A. Saxena, D. Mondhe, 2007, Planta medica.

Antitumor efficacy and apoptotic activity of substituted chloroalkyl 1H-benz[de]isoquinoline-1,3-diones: a new class of potential antineoplastic agents

Shashank K Singh, A. Saxena, D. Mondhe, 2011, Investigational New Drugs.

Synergistic combination of PMBA and 5-fluorouracil (5-FU) in targeting mutant KRAS in 2D and 3D colorectal cancer cells

Shashank K Singh, B. A. Shah, Utpal Nandi, 2022, Heliyon.

MINOR FRUITS OF JAMMU SUBTROPICS POSSESS IN VITRO CYTOTOXICITY AGAINST HUMAN CANCER CELLS

Shashank K Singh, Vikas Sharma, Sweeta Manhas, 2018 .

Potentiation of the antitumor effect of 11-keto-β-boswellic acid by its 3-α-hexanoyloxy derivative.

Shashank K Singh, S. C. Taneja, B. A. Shah, 2011, European journal of pharmacology.

Chitosan Engineered PAMAM Dendrimers as Nanoconstructs for the Enhanced Anti-Cancer Potential and Improved In vivo Brain Pharmacokinetics of Temozolomide

Ajazuddin, Shashank K Singh, U. Gupta, 2018, Pharmaceutical Research.

Coronarin K and L: Two Novel Labdane Diterpenes From Roscoea purpurea: An Ayurvedic Crude Drug

Shashank K Singh, Pankaj Kumar, V. Singamaneni, 2021, Frontiers in Chemistry.

Antimicrobial and Cytotoxic Potential of Helminthosporin from Rumex abyssiniscus Jacq. Discovered as a Novel Source of Syringic Acid and Bis(2-ethyloctyl) Phthalate

Shashank K Singh, S. Bharate, Sumit G. Gandhi, 2022, Current Microbiology.

1,2,3-Triazole Tethered Hybrid Capsaicinoids as Antiproliferative Agents Active against Lung Cancer Cells (A549)

Shashank K Singh, S. Parveen, B. Lone, 2022, ACS omega.

Combined effect of microRNA, nutraceuticals and drug on pancreatic cancer cell lines.

Shashank K Singh, S. Vaishnavi, R. Bamezai, 2015, Chemico-biological interactions.

Synergistic Combination of Gemcitabine and Dietary Molecule Induces Apoptosis in Pancreatic Cancer Cells and Down Regulates PKM2 Expression

Shashank K Singh, S. Vaishnavi, R. Bamezai, 2014, PloS one.

Biodegradable nano-architectural PEGylated approach for the improved stability and anticancer efficacy of bendamustine.

Shashank K Singh, U. Gupta, A. Sharma, 2016, International journal of biological macromolecules.

Long-circulatory nanoparticles for gemcitabine delivery: Development and investigation of pharmacokinetics and in-vivo anticancer efficacy.

Shashank K Singh, A. Saxena, D. Mondhe, 2016, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Empagliflozin containing chitosan-alginate nanoparticles in orodispersible film: preparation, characterization, pharmacokinetic evaluation and its in-vitro anticancer activity

Shashank K Singh, Sonali, R. Dutt, 2022, Drug development and industrial pharmacy.

NF-κB down-regulation and PARP cleavage by novel 3-α-butyryloxy-β-boswellic acid results in cancer cell specific apoptosis and in vivo tumor regression.

Shashank K Singh, S. C. Taneja, B. A. Shah, 2013, Anti-Cancer Agents in Medicinal Chemistry.

Biologically active xanthones from Codonopsis ovata.

A. Raina, Shashank K Singh, P. Sangwan, 2016, Phytochemistry.