J. Maguire

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Akt1 Regulates Vascular Smooth Muscle Cell Apoptosis Through FoxO3a and Apaf1 and Protects Against Arterial Remodeling and Atherosclerosis

T. Littlewood, M. Bennett, Haixiang Yu, 2014, Arteriosclerosis, thrombosis, and vascular biology.

Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis

T. Littlewood, M. Goddard, M. Bennett, 2006, Nature Medicine.

Intracellular Interleukin-1 Receptor 2 Binding Prevents Cleavage and Activity of Interleukin-1α, Controlling Necrosis-Induced Sterile Inflammation

M. Bennett, J. Maguire, Yue Zheng, 2013, Immunity.

Pharmacological specificity of novel, synthetic, cyclic peptides as antagonists at tachykinin receptors

L. Iversen, J. Maguire, J. Maguire, 1991, British journal of pharmacology.

Discovering orphan receptor function using human in vitro pharmacology.

J. Maguire, 2003, Current opinion in pharmacology.

Plasma levels of apelin are reduced in patients with liver fibrosis and cirrhosis but are not correlated with circulating levels of bone morphogenetic protein 9 and 10

G. Alexander, A. Davenport, N. Morrell, 2020, Peptides.

In vitro metabolism of synthetic Elabela/Toddler (ELA-32) peptide in human plasma and kidney homogenates analyzed with mass spectrometry and validation of endogenous peptide quantification in tissues by ELISA

F. Gribble, A. Davenport, J. Maguire, 2021, Peptides.

Chemerin Elicits Potent Constrictor Actions via Chemokine‐Like Receptor 1 (CMKLR1), not G‐Protein‐Coupled Receptor 1 (GPR1), in Human and Rat Vasculature

Colin W. Taylor, A. Davenport, J. Maguire, 2016, Journal of the American Heart Association.

Advances in therapeutic peptides targeting G protein-coupled receptors

Chris de Graaf, Anthony P. Davenport, Janet J. Maguire, 2020, Nature Reviews Drug Discovery.

The CCR5 chemokine receptor mediates vasoconstriction and stimulates intimal hyperplasia in human vessels in vitro

M. Bennett, A. Davenport, J. Maguire, 2013, Cardiovascular research.

Endothelin@25 – new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR Review 12

A. Davenport, J. Maguire, J. Maguire, 2014, British journal of pharmacology.

Apelin peptides linked to anti‐serum albumin domain antibodies retain affinity in vitro and are efficacious receptor agonists in vivo

Lucy J. Holt, R. Glen, A. Davenport, 2020, Basic & clinical pharmacology & toxicology.

Immunocytochemical localization of the urotensin-II receptor, UT, to rat and human tissues: Relevance to function

A. Davenport, J. Maguire, R. Kuc, 2008, Peptides.

Discovery of recently adopted orphan receptors for apelin, urotensin II, and ghrelin identified using novel radioligands and functional role in the human cardiovascular system.

A. Davenport, J. Maguire, R. Kuc, 2002, Canadian journal of physiology and pharmacology.

Is urotensin‐II the new endothelin?

A. Davenport, J. Maguire, 2002, British journal of pharmacology.

Urotensin II: fish neuropeptide catches orphan receptor.

A. Davenport, J. Maguire, J. Maguire, 2000, Trends in pharmacological sciences.

Orphan‐receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin‐1

A. Davenport, J. Maguire, R. Kuc, 2000, British journal of pharmacology.

Characterization of [¹²⁵I]GLP-1(9-36), a novel radiolabeled analog of the major metabolite of glucagon-like peptide 1 to a receptor distinct from GLP1-R and function of the peptide in murine aorta.

A. Davenport, J. Maguire, R. Kuc, 2014, Life sciences.

International Union of Pharmacology. LXXII. Recommendations for Trace Amine Receptor Nomenclature

R. Neubig, T. Bonner, A. Davenport, 2009, Pharmacological Reviews.

Trace amine receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

T. Bonner, A. Davenport, J. Maguire, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

Apelin Receptor Nomenclature , Distribution , Pharmacology , and Function

T. Bonner, A. Davenport, J. Maguire, 2010 .

Development and validation of an LC-MS/MS method for detection and quantification of in vivo derived metabolites of [Pyr1]apelin-13 in humans

F. Reimann, F. Gribble, A. Davenport, 2019, Scientific Reports.

A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension

R. Glen, S. Sawiak, A. Davenport, 2019, British journal of pharmacology.

Abstract 15352: ELABELA/Toddler, a Critical Regulator of Cardiac Development, is Expressed in the Human Cardiovascular System and Binds the Apelin Receptor

R. Glen, Rubben Torella, A. Davenport, 2014 .

Davenport and Maguire reply

A. Davenport, J. Maguire, 1994 .

Endothelin‐2, the forgotten isoform: emerging role in the cardiovascular system, ovarian development, immunology and cancer

A. Davenport, J. Maguire, L. Ling, 2013, British journal of pharmacology.

Identification and cellular localisation of NPW1 (GPR7) receptors for the novel neuropeptide W-23 by [125I]-NPW radioligand binding and immunocytochemistry

A. Davenport, J. Maguire, M. Fidock, 2004, Brain Research.

Human endothelin receptors characterized using reverse transcriptase-polymerase chain reaction, in situ hybridization, and subtype-selective ligands BQ123 and BQ3020: evidence for expression of ETB receptors in human vascular smooth muscle.

A. Davenport, J. Maguire, P. Molenaar, 1993, Journal of cardiovascular pharmacology.

Cellular distribution of immunoreactive urotensin-II in human tissues with evidence of increased expression in atherosclerosis and a greater constrictor response of small compared to large coronary arteries

A. Davenport, J. Maguire, R. Kuc, 2004, Peptides.

[125I]‐(Pyr1)Apelin‐13 is a novel radioligand for localizing the APJ orphan receptor in human and rat tissues with evidence for a vasoconstrictor role in man

A. Davenport, J. Maguire, S. Katugampola, 2001, British journal of pharmacology.

Elevated systemic levels of endothelin-1 and blood pressure correlate with blunted constrictor responses and downregulation of endothelin(A), but not endothelin(B), receptors in an animal model of hypertension.

M. Yanagisawa, A. Davenport, J. Maguire, 2002, Clinical science.

Endothelin-converting enzyme activity in vascular smooth muscle preparations in vitro.

J. Maguire, 2002, Methods in molecular biology.

Changes in biomechanical properties of the coronary artery wall contribute to maintained contractile responses to endothelin-1 in atherosclerosis.

M. Sutcliffe, A. Davenport, J. Maguire, 2014, Life sciences.

Radioligand binding assays and their analysis.

A. Davenport, J. Maguire, R. Kuc, 2012, Methods in molecular biology.

Importance of Subtype Selectivity for Endothelin Receptor Antagonists in the Human Vasculature

A. Davenport, J. Maguire, 2012 .

Pharmacology of renal endothelin receptors.

A. Davenport, J. Maguire, 2011, Contributions to nephrology.

Vasoconstrictor activity of novel endothelin peptide, ET‐1(1 – 31), in human mammary and coronary arteries in vitro

A. Davenport, J. Maguire, R. Kuc, 2001, British journal of pharmacology.

Modulation of the apelin/APJ system in heart failure and atherosclerosis in man

A. Davenport, J. Maguire, R. Kuc, 2010, British journal of pharmacology.

Modulation of endothelin receptors in the failing right ventricle of the heart and vasculature of the lung in human pulmonary arterial hypertension

A. Davenport, N. Morrell, J. Maguire, 2014, Life sciences.

Endothelin Receptors and Their Antagonists☆☆☆

A. Davenport, J. Maguire, 2015, Seminars in nephrology.

Regional heterogeneity in the haemodynamic responses to urotensin II infusion in relation to UT receptor localisation

A. Davenport, J. Maguire, S. Gardiner, 2006, British journal of pharmacology.

Endothelin-Mediated Vasoconstriction in Early Atherosclerosis Is Markedly Increased in ApoE−/− Mouse but Prevented by Atorvastatin

M. Bennett, A. Davenport, J. Maguire, 2006, Experimental biology and medicine.

Inotropic Action of the Puberty Hormone Kisspeptin in Rat, Mouse and Human: Cardiovascular Distribution and Characteristics of the Kisspeptin Receptor

W. Colledge, A. Davenport, J. Maguire, 2011, PloS one.

International Union of Basic and Clinical Pharmacology. LXXVII. Kisspeptin Receptor Nomenclature, Distribution, and Function

W. Colledge, A. Davenport, J. Maguire, 2010, Pharmacological Reviews.

Increased response to big endothelin‐1 in atherosclerotic human coronary artery: functional evidence for up‐regulation of endothelin‐converting enzyme activity in disease

A. Davenport, J. Maguire, 1998, British journal of pharmacology.

G-protein-coupled receptors in human atherosclerosis: comparison of vasoconstrictors (endothelin and thromboxane) with recently de-orphanized (urotensin-II, apelin and ghrelin) receptors.

A. Davenport, J. Maguire, R. Kuc, 2002, Clinical science.

Apelin receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

A. Davenport, J. Maguire, Peiran Yang, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

Characterization of the snake venom ligand [125I]‐DNP binding to natriuretic peptide receptor‐A in human artery and potent DNP mediated vasodilatation

J. Skepper, A. Davenport, J. Maguire, 2006, British journal of pharmacology.

Differential expression in humans of the viral entry receptor ACE2 compared with the short deltaACE2 isoform lacking SARS-CoV-2 binding sites

A. Davenport, J. Maguire, S. Sinha, 2021, Scientific Reports.

Genes encoding ACE2, TMPRSS2 and related proteins mediating SARS-CoV-2 viral entry are upregulated with age in human cardiomyocytes

O. Bergmann, H. Roderick, A. Davenport, 2020, bioRxiv.

Failure of BQ123, a more potent antagonist of sarafotoxin 6b than of endothelin‐1, to distinguish between these agonists in binding experiments

A. Davenport, J. Maguire, R. Kuc, 1996, British journal of pharmacology.

[Pyr1]Apelin-13(1–12) Is a Biologically Active ACE2 Metabolite of the Endogenous Cardiovascular Peptide [Pyr1]Apelin-13

R. Glen, M. Singer, I. Wilkinson, 2017, Front. Neurosci..

Trans-myocardial Extraction of Endothelin-1 Correlates with Increased Microcirculatory Resistance following Percutaneous Coronary Intervention

A. Davenport, J. Maguire, R. Kuc, 2022, Journal of interventional cardiology.

Endothelin-1 is increased in the plasma of patients hospitalised with Covid-19

I. Wilkinson, A. Davenport, J. Maguire, 2022, Journal of Molecular and Cellular Cardiology.

Novel Snake Venom Ligand Dendroaspis Natriuretic Peptide Is Selective for Natriuretic Peptide Receptor-A in Human Heart: Downregulation of Natriuretic Peptide Receptor-A in Heart Failure

A. Davenport, J. Maguire, M. Fidock, 2006, Circulation research.

Affinity and selectivity of PD156707, a novel nonpeptide endothelin antagonist, for human ET(A) and ET(B) receptors.

A. Davenport, J. Maguire, R. Kuc, 1997, The Journal of pharmacology and experimental therapeutics.

[125I]‐PD 151242: a selective radioligand for human ETA receptors

A. Doherty, A. Davenport, J. Maguire, 1994, British journal of pharmacology.

The endothelin system in human saphenous vein graft disease.

A. Davenport, J. Maguire, 2001, Current opinion in pharmacology.

PD156707: a potent antagonist of endothelin-1 in human diseased coronary arteries and vein grafts.

A. Davenport, J. Maguire, 1998, Journal of cardiovascular pharmacology.

Comparison of endothelin receptors in normal versus cirrhotic human liver and in the liver from endothelial cell-specific ETB knockout mice.

D. Webb, G. Alexander, A. Davenport, 2012, Life sciences.

Cyclic peptides as selective tachykinin antagonists.

D. Veber, J. Maguire, B. Williams, 1993, Journal of medicinal chemistry.

Kisspeptin receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

A. Davenport, J. Maguire, E. J. Mead, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

Ghrelin receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

B. Holst, A. Davenport, J. Maguire, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

Functional and immunocytochemical evidence for a role of ghrelin and des-octanoyl ghrelin in the regulation of vascular tone in man.

J. Skepper, A. Davenport, J. Maguire, 2006, Cardiovascular research.

L‐683,877: Pharmacological profile of a novel 5‐HT3 receptor antagonist

N. Newberry, M. Rigby, J. Maguire, 1992 .

Bile acid receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

Edward M. Rosser, T. Bonner, A. Davenport, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human Adrenal

Morris J. Brown, G. McKenzie, G. Yeo, 2015, The Journal of clinical endocrinology and metabolism.

LGR 5 activates non-canonical Wnt-signaling and inhibits aldosterone 1 production in the human adrenal 2 3

Morris J. Brown, G. McKenzie, G. Yeo, 2015 .

Positron emission tomography of [18F]‐big endothelin‐1 reveals renal excretion but tissue‐specific conversion to [18F]‐endothelin‐1 in lung and liver

J. Pickard, T. Fryer, A. Davenport, 2010, British journal of pharmacology.

ETA receptor antagonists inhibit intimal smooth muscle cell proliferation in human vessels.

A. Davenport, J. Maguire, Julie C.M. Yu, 2002, Clinical science.

Of mice and men: advances in endothelin research and first antagonist gains FDA approval.

A. Davenport, J. Maguire, 2002, Trends in pharmacological sciences.

Evidence for biased agonists and antagonists at the endothelin receptors

J. Maguire, 2016, Life sciences.

Comparison of human ETA and ETB receptor signalling via G-protein and β-arrestin pathways.

A. Davenport, J. Maguire, V. Pell, 2012, Life sciences.

Apelin is expressed throughout the human kidney, is elevated in chronic kidney disease & associates independently with decline in kidney function

D. Newby, A. Davenport, J. Maguire, 2022, British journal of clinical pharmacology.

ETA Receptors Predominate in the Human Vasculature and Mediate Constriction

A. Davenport, J. Maguire, R. Kuc, 1995, Journal of cardiovascular pharmacology.

ET-A Endothelin Receptor

A. Davenport, J. Maguire, 2008 .

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors

Stephen P. H. Alexander, Leigh A. Stoddart, Kalyan C. Tirupula, 2021, British journal of pharmacology.

Design, Characterization, and First-In-Human Study of the Vascular Actions of a Novel Biased Apelin Receptor Agonist

Robert C. Glen, Joseph Cheriyan, Anthony P. Davenport, 2015, Hypertension.

Aspects of the molecular pharmacology of GABAB receptors

N. Bowery, J. Maguire, G. Pratt, 1991 .

Endothelin

S. Matalon, A. Davenport, J. Maguire, 1992, Clinical Physiology Series.

Endothelin receptor expression and pharmacology in human saphenous vein graft

A. Davenport, J. Maguire, 1999, British journal of pharmacology.

Development of NK-2 selective antagonists

J. Maguire, B. Williams, A. McKnight, 1988, Regulatory Peptides.

Chronic Apoptosis of Vascular Smooth Muscle Cells Accelerates Atherosclerosis and Promotes Calcification and Medial Degeneration

T. Littlewood, M. Goddard, M. Bennett, 2008, Circulation research.

Pharmacological specificity of synthetic peptides as antagonists at tachykinin receptors

L. Iversen, J. Maguire, A. Foster, 1988, Regulatory Peptides.

Conformationally constrained tachykinin analogs which are selective ligands for the eledoisin binding site.

D. Veber, R. Freidinger, J. Maguire, 1986, Molecular pharmacology.

Kisspeptins are novel potent vasoconstrictors in humans, with a discrete localization of their receptor, G protein-coupled receptor 54, to atherosclerosis-prone vessels.

A. Davenport, J. Maguire, R. Kuc, 2007, Endocrinology.

A novel series of non‐quaternary oxadiazoles acting as full agonists at muscarinic receptors

L. Iversen, N. Newberry, J. Maguire, 1990, British journal of pharmacology.

Kisspeptins: a multifunctional peptide system with a role in reproduction, cancer and the cardiovascular system

A. Davenport, J. Maguire, R. Kuc, 2007, British journal of pharmacology.

Endothelin

C. Southan, D. Webb, J. Pollock, 2016, Pharmacological Reviews.

Advances in therapeutic peptides targeting G protein-coupled receptors

C. de Graaf, A. Davenport, J. Maguire, 2020, Nature Reviews Drug Discovery.

International Union of Basic and Clinical Pharmacology. LXXIV. Apelin Receptor Nomenclature, Distribution, Pharmacology, and Function

T. Bonner, A. Davenport, J. Maguire, 2010, Pharmacological Reviews.

Neuropeptide W/neuropeptide B receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

A. Davenport, J. Maguire, Gurminder Singh, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension

R. Glen, T. Carpenter, S. Sawiak, 2017, Circulation.

Apelin-36-[L28A] and Apelin-36-[L28C(30kDa-PEG)] peptides that improve diet induced obesity are G protein biased ligands at the apelin receptor

M. Bednarek, A. Davenport, L. Jermutus, 2019, Peptides.

Cardiac action of the first G protein biased small molecule apelin agonist

R. Glen, A. Davenport, J. Maguire, 2016, Biochemical pharmacology.

Discovery of a Competitive Apelin Receptor (APJ) Antagonist

R. Glen, A. Davenport, J. Maguire, 2011, ChemMedChem.

International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand

R. Glen, A. Davenport, D. Huggins, 2019, Pharmacological Reviews.

[Pyr1]Apelin-13 Identified as the Predominant Apelin Isoform in the Human Heart: Vasoactive Mechanisms and Inotropic Action in Disease

A. Davenport, J. Maguire, M. Kleinz, 2009, Hypertension.

Regulation of vascular reactivity by established and emerging GPCRs.

A. Davenport, J. Maguire, 2005, Trends in pharmacological sciences.

Genetic dysregulation of endothelin-1 is implicated in coronary microvascular dysfunction

N. Sattar, A. Arai, C. Berry, 2020, European heart journal.

The dual endothelin converting enzyme/neutral endopeptidase inhibitor SLV-306 (daglutril), inhibits systemic conversion of big endothelin-1 in humans.

J. McMurray, A. Davenport, J. Maguire, 2012, Life sciences.

Endothelin@25 – new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR Review 12

A. Davenport, J. Maguire, J. Maguire, 2014, British journal of pharmacology.

Is endothelin-induced vasoconstriction mediated only by ETA receptors in humans?

A. Davenport, J. Maguire, 1994, Trends in pharmacological sciences.

Vasoconstrictor endothelin receptors characterized in human renal artery and vein in vitro

A. Davenport, J. Maguire, R. Kuc, 1994, British journal of pharmacology.

Endothelial cell-specific ETB receptor knockout: autoradiographic and histological characterisation and crucial role in the clearance of endothelin-1.

D. Webb, A. Davenport, J. Maguire, 2010, Canadian journal of physiology and pharmacology.

Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system

A. Davenport, J. Maguire, Peiran Yang, 2015, Trends in pharmacological sciences.

The therapeutic potential of apelin in kidney disease

D. Newby, A. Davenport, J. Maguire, 2021, Nature Reviews Nephrology.

Expanding the apelin receptor pharmacological toolbox using novel fluorescent ligands

A. Davenport, J. Maguire, Alastair J. H. Brown, 2023, Frontiers in Endocrinology.

The G Protein Biased Small Molecule Apelin Agonist CMF-019 is Disease Modifying in Endothelial Cell Apoptosis In Vitro and Induces Vasodilatation Without Desensitisation In Vivo

R. Glen, A. Davenport, J. Maguire, 2021, Frontiers in Pharmacology.

QRFP receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

Anthony P. Davenport, Tom I. Bonner, Didier Bagnol, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

Expression and vasoconstrictor function of anorexigenic peptides neuromedin U-25 and S in the human cardiovascular system.

A. Davenport, J. Maguire, R. Kuc, 2008, Cardiovascular research.

J. Maguire, N. Bowery, C. Knott, 1993, Brain research. Molecular brain research.

Regional effects of pertussis toxin in vivo and in vitro on GABAB receptor binding in rat brain

R. Moratalla, J. Maguire, N. Bowery, 1993, Neuroscience.

Endothelin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

A. Davenport, J. Maguire, E. Ohlstein, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

New drugs and emerging therapeutic targets in the endothelin signaling pathway and prospects for personalized precision medicine.

C. Southan, A. Davenport, J. Maguire, 2018, Physiological research.

Ghrelin receptor in GtoPdb v.2023.1 Ghrelin receptor in GtoPdb v.2023.1

B. Holst, A. Davenport, J. Maguire, 2023 .

ETA receptor‐mediated constrictor responses to endothelin peptides in human blood vessels in vitro

A. Davenport, J. Maguire, 1995, British journal of pharmacology.

Endothelin receptors in GtoPdb v.2023.1

A. Davenport, J. Maguire, E. Ohlstein, 2023, IUPHAR/BPS Guide to Pharmacology CITE.

Defining the affinity and receptor sub-type selectivity of four classes of endothelin antagonists in clinically relevant human cardiovascular tissues.

A. Davenport, J. Maguire, R. Kuc, 2012, Life sciences.

Human embryonic stem cell-derived cardiomyocyte platform screens inhibitors of SARS-CoV-2 infection

S. Bloor, P. Lehner, A. Davenport, 2021, Communications Biology.

Endothelin converting enzyme (ECE) activity in human vascular smooth muscle

A. Davenport, J. Maguire, J. Mockridge, 1997, British journal of pharmacology.

Apelin receptor in GtoPdb v.2023.1 Apelin receptor in GtoPdb v.2023.1

A. Davenport, J. Maguire, Peiran Yang, 2023 .

Quantification of Endothelin Receptor Subtypes in Peripheral Tissues Reveals Downregulation of ETA Receptors in ETB-Deficient Mice

A. Davenport, J. Maguire, R. Kuc, 2006, Experimental biology and medicine.

Trace amine receptor in GtoPdb v.2023.1

T. Bonner, A. Davenport, J. Maguire, 2023, IUPHAR/BPS Guide to Pharmacology CITE.

The therapeutic potential of PD156707 and related butenolide endothelin antagonists.

A. Davenport, J. Maguire, 1999, Expert opinion on investigational drugs.

Characterisation of tachykinin receptors using selectivity of agonists and antagonists: Evidence for an NK-4 type

L. Iversen, J. Maguire, B. Williams, 1988, Regulatory Peptides.

Inducible apelin receptor knockdown reduces differentiation efficiency and contractility of hESC-derived cardiomyocytes

A. Davenport, J. Maguire, S. Sinha, 2022, Cardiovascular research.

A rational roadmap for SARS‐CoV‐2/COVID‐19 pharmacotherapeutic research and development: IUPHAR Review 29

C. Southan, M. Spedding, J. Armstrong, 2020, British journal of pharmacology.

QRFP receptor in GtoPdb v.2023.1

D. Larhammar, T. Bonner, H. Vaudry, 2023, IUPHAR/BPS Guide to Pharmacology CITE.

Bile acid receptor in GtoPdb v.2023.1

Edward M. Rosser, T. Bonner, A. Davenport, 2023, IUPHAR/BPS Guide to Pharmacology CITE.

Intracellular il-1 receptor 2 binding prevents cleavage and activity of IL-1ALPHA, controlling necrosis-induced sterile inflammation

M. Bennett, J. Maguire, M. Humphry, 2012 .

Current and future strategies for targeting the endothelin pathway in cardiovascular disease

A. Davenport, J. Maguire, George R. Abraham, 2023, Nature Cardiovascular Research.

Endothelin-1 is increased in the plasma of patients hospitalised with Covid-19

A. Davenport, J. Maguire, R. Kuc, 2022, Journal of Molecular and Cellular Cardiology.

Targeting the apelin system for the treatment of cardiovascular diseases

A. Davenport, J. Maguire, N. Dhaun, 2023, Cardiovascular research.

Intracellular Interleukin-1 Receptor 2 Binding Prevents Cleavage and Activity of Interleukin-1α, Controlling Necrosis-Induced Sterile Inflammation

J. Maguire, M. Humphry, Murray C H Clarke, 2013, Immunity.

The biased apelin receptor agonist, MM07, reverses Sugen/hypoxia-induced pulmonary arterial hypertension as effectively as the endothelin antagonist macitentan

J. Maguire, R. Kuc, Duuamene Nyimanu, 2024, Frontiers in Pharmacology.

THEMED ISSUE: GPCR REVIEW Emerging pharmacology and physiology of neuromedin U and the structurally related peptide neuromedin S

A. Davenport, J. Maguire, John D. Mitchell, 2009 .

Trans-myocardial Extraction of Endothelin-1 Correlates with Increased Microcirculatory Resistance following Percutaneous Coronary Intervention

A. Davenport, J. Maguire, R. Kuc, 2022, Journal of interventional cardiology.