K. Pindolia

发表

Pristimerin, a quinonemethide triterpenoid, induces apoptosis in pancreatic cancer cells through the inhibition of pro-survival Akt/NF-κB/mTOR signaling proteins and anti-apoptotic Bcl-2

D. Deeb, Xiaohua Gao, S. Gautam, 2014, International journal of oncology.

A rapid and sensitive approach to mutation detection using real-time polymerase chain reaction and melting curve analyses, using BRCA1 as an example.

G. Pals, K. Pindolia, M. Worsham, 1999, Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology.

TNF-alpha gene therapy with myeloid progenitor cells lacks the toxicities of systemic TNF-alpha therapy.

S. Gautam, K. Pindolia, N. Janakiraman, 1999, Journal of hematotherapy.

IL1α and TNFα Induction of Monocyte Chemoattractant Protein-1 (MCP-1/JE) in Bone Marrow Stromal Cells: The Role of Protein Kinase C (PKC) and Protein Tyrosine Kinase (PTK) Activity.

S. Gautam, K. Pindolia, N. Janakiraman, 1998, Hematology.

Chemokine gene expression in bone marrow stromal cells: downregulation with sodium salicylate.

S. Gautam, K. Pindolia, N. Janakiraman, 1995, Blood.

Analysis of mutations causing biotinidase deficiency a

K. Pindolia, B. Wolf, M. Jordan, 2010, Human mutation.

First contiguous gene deletion causing biotinidase deficiency: The enzyme deficiency in three Sri Lankan children

K. Pindolia, B. Wolf, J. Wanigasinghe, 2015, Molecular genetics and metabolism reports.

Antileukemic Activity of TNF-α Therapy with Myeloid Progenitor Cells Against Minimal Leukemia

S. Gautam, K. Pindolia, S. Freytag, 1998 .

Developmental window of sensorineural deafness in biotinidase-deficient mice

K. Pindolia, B. Wolf, A. Gow, 2017, Journal of Inherited Metabolic Disease.

Nonselective inhibition of proliferation of transformed and nontransformed cells by the anticancer agent curcumin (diferuloylmethane).

S. Gautam, K. Pindolia, N. Janakiraman, 1998, Biochemical pharmacology.

Three dimensional structure of human biotinidase: computer modeling and functional correlations.

K. Pindolia, B. Wolf, K. Jensen, 2007, Molecular Genetics and Metabolism.

Candidate disorders for gene therapy: newborn screening facilitates ascertainment of presymptomatic individuals.

K. Pindolia, B. Wolf, 2008, Human gene therapy.

Development and characterization of a mouse with profound biotinidase deficiency: a biotin-responsive neurocutaneous disorder.

Caiying Guo, M. Blitzer, K. Pindolia, 2011, Molecular genetics and metabolism.

Human Mutation MUTATION UPDATE Analysis of Mutations Causing Biotinidase Deficiency

K. Pindolia, B. Wolf, M. Jordan, 2010 .

Characterization and functional analysis of cellular immunity in mice with biotinidase deficiency.

K. Pindolia, B. Wolf, Hong Li, 2014, Molecular genetics and metabolism.

Neurological deficits in mice with profound biotinidase deficiency are associated with demylination and axonal degeneration

M. Chopp, K. Pindolia, Jieli Chen, 2012, Neurobiology of Disease.

Ubiquitin-proteasomal degradation of antiapoptotic survivin facilitates induction of apoptosis in prostate cancer cells by pristimerin

Xiaohua Gao, Yiguan Zhang, J. Shaw, 2014, International journal of oncology.

Biotin and biotin-responsive disorders

K. Pindolia, B. Wolf, 2010 .

Biotinidase knockout mice show cellular energy deficit and altered carbon metabolism gene expression similar to that of nutritional biotin deprivation: clues for the pathogenesis in the human inherited disorder.

K. Pindolia, B. Wolf, I. Ibarra-González, 2013, Molecular genetics and metabolism.

Biotinidase deficiency mimicking neuromyelitis optica: Initially exhibiting symptoms in adulthood

K. Pindolia, B. Stankoff, B. Wolf, 2015, Multiple sclerosis.

Differential gene expression during early development in brains of wildtype and biotinidase-deficient mice

K. Pindolia, B. Wolf, Chris Brigolin, 2016, Molecular genetics and metabolism reports.

Curcumin, a compound with anti-inflammatory and anti-oxidant properties, down-regulates chemokine expression in bone marrow stromal cells.

S. Gautam, K. Pindolia, N. Janakiraman, 1997, Experimental hematology.

Inhibition of cell proliferation and induction of apoptosis by oleanane triterpenoid (CDDO-Me) in pancreatic cancer cells is associated with the suppression of hTERT gene expression and its telomerase activity.

D. Deeb, Xiaohua Gao, Yongbo Liu, 2012, Biochemical and biophysical research communications.

Induction of chemokine mRNA in bone marrow stromal cells: modulation by TGF-beta 1 and IL-4.

S. Gautam, K. Pindolia, N. Janakiraman, 1995, Experimental hematology.

Mutations in the von Hippel‐Lindau (VHL) gene refine differential diagnostic criteria in renal cell carcinoma

M. Amin, M. Amin, K. Pindolia, 2002, Journal of surgical oncology.

Induction of Apoptosis in Pancreatic Cancer Cells by CDDO-Me Involves Repression of Telomerase through Epigenetic Pathways

D. Deeb, Xiaohua Gao, Yongbo Liu, 2014, Journal of carcinogenesis & mutagenesis.

Enhanced assessment of allogeneic bone marrow transplant engraftment using automated fluorescent-based typing

G. Pals, K. Pindolia, C. Kasten‐Sportès, 1999, Bone Marrow Transplantation.

Inhibition of hTERT/telomerase contributes to the antitumor activity of pristimerin in pancreatic ductal adenocarcinoma cells

D. Deeb, Xiaohua Gao, Yongbo Liu, 2015, Oncology reports.

Purification and characterization of the simian virus 40 transcription elongation complex.

L. Lutter, K. Pindolia, 2005, Journal of molecular biology.

Curcumin inhibits IL1 alpha and TNF-alpha induction of AP-1 and NF-kB DNA-binding activity in bone marrow stromal cells.

S. Gautam, K. Pindolia, N. Janakiraman, 1997, Hematopathology and molecular hematology.

Role of telomerase in anticancer activity of pristimerin in prostate cancer cells.

D. Deeb, Xiaohua Gao, S. Gautam, 2017, Journal of experimental therapeutics and oncology.

IL-4 upregulates IL-1-induced chemokine gene expression in bone marrow stromal cells by enhancing NF-kB activation.

S. Gautam, K. Pindolia, N. Janakiraman, 1996, Hematopathology and molecular hematology.