D. Glass

发表

Signaling pathways controlling skeletal muscle mass

M. Egerman, D. Glass, Marc A. Egerman, 2013, Critical reviews in biochemistry and molecular biology.

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

D J Glass, C. Rommel, G. Yancopoulos, 1999, Science.

Abnormal Behavior of Zebrafish Mutant in Dopamine Transporter Is Rescued by Clozapine

M. Fishman, P. Zhu, D. Glass, 2019, iScience.

Voluntary running, skeletal muscle gene expression, and signaling inversely regulated by orchidectomy and testosterone replacement.

Qicheng Ma, D. Glass, Christine Li, 2011, American journal of physiology. Endocrinology and metabolism.

Treatment of sporadic inclusion body myositis with bimagrumab

B. Tseng, S. Greenberg, J. Praestgaard, 2014, Neurology.

Electrical Impedance as a Novel Biomarker of Myotube Atrophy and Hypertrophy

S. Rakhilin, D. Glass, Y. Abassi, 2011, Journal of biomolecular screening.

Molecular mechanisms and treatment options for muscle wasting diseases.

D. Glass, M. Rüegg, 2011, Annual review of pharmacology and toxicology.

IGF-1 Regulation of Skeletal Muscle Hypertrophy and Atrophy

D. Glass, 2010 .

PI3 kinase regulation of skeletal muscle hypertrophy and atrophy.

D. Glass, 2010, Current topics in microbiology and immunology.

Skeletal muscle hypertrophy and atrophy signaling pathways.

D. Glass, David J Glass, 2005, The international journal of biochemistry & cell biology.

Molecular mechanisms modulating muscle mass.

D. Glass, David J Glass, 2003, Trends in molecular medicine.

The role of GDF11 in aging and skeletal muscle, cardiac and bone homeostasis

M. Egerman, D. Glass, 2019, Critical reviews in biochemistry and molecular biology.

mTORC1 and PKB/Akt control the muscle response to denervation by regulating autophagy and HDAC4

Shuo Lin, D. Glass, M. Rüegg, 2019, Nature Communications.

Mapping sites responsible for interactions of agrin with neurons

J. Sanes, D. Dickman, R. Burgess, 2002, Journal of neurochemistry.

Agrin in Alzheimer's disease: altered solubility and abnormal distribution within microvasculature and brain parenchyma.

M. Rafii, T. Berzin, G. Yancopoulos, 1999, Proceedings of the National Academy of Sciences of the United States of America.

G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy

B. Spiegelman, S. Gygi, Mark P. Jedrychowski, 2014, Proceedings of the National Academy of Sciences.

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

G. Yancopoulos, S. Bodine, D. Glass, 2001, Nature Cell Biology.

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation

S. Gygi, A. Goldberg, C. Gartner, 2009, The Journal of cell biology.

Pharmacological Characterization of a Novel 5-Hydroxybenzothiazolone-Derived β2-Adrenoceptor Agonist with Functional Selectivity for Anabolic Effects on Skeletal Muscle Resulting in a Wider Cardiovascular Safety Window in Preclinical Studies

S. Hatakeyama, T. Ullrich, D. Glass, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Kinase domain of the muscle-specific receptor tyrosine kinase (MuSK) is sufficient for phosphorylation but not clustering of acetylcholine receptors: required role for the MuSK ectodomain?

J. Sanes, G. Yancopoulos, D. Glass, 1997, Proceedings of the National Academy of Sciences of the United States of America.

The SCF-Fbxo40 complex induces IRS1 ubiquitination in skeletal muscle, limiting IGF1 signaling.

D. Glass, Jun Shi, C. Ibebunjo, 2011, Developmental cell.

MG53′s new identity

K. Campbell, D. Glass, Jennifer R. Levy, 2013, Skeletal Muscle.

Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size.

S. Hatakeyama, D. Glass, A. Trendelenburg, 2009, American journal of physiology. Cell physiology.

TAK-1/p38/nNFκB signaling inhibits myoblast differentiation by increasing levels of Activin A

C. Jacobi, D. Glass, J. Feige, 2012, Skeletal Muscle.

An Antibody Blocking Activin Type II Receptors Induces Strong Skeletal Muscle Hypertrophy and Protects from Atrophy

S. Brachat, S. Hatakeyama, D. Glass, 2013, Molecular and Cellular Biology.

GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration.

I. Clay, S. Brachat, C. Jacobi, 2015, Cell metabolism.

Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy

C. Jacobi, Alain Schilb, M. Scharenberg, 2017, Proceedings of the National Academy of Sciences.

Supraphysiologic Administration of GDF11 Induces Cachexia in Part by Upregulating GDF15.

D. Glass, Juli E Jones, Chenguang Gong, 2018, Cell reports.

Insulin-like Growth Factor-1 (IGF-1) Inversely Regulates Atrophy-induced Genes via the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Pathway*

Hsin C. Lin, Francis J. Martin, Yi Wei, 2005, Journal of Biological Chemistry.

MAFbx/Atrogin-1 is required for atrophic remodeling of the unloaded heart.

O. Frazier, D. Glass, H. Taegtmeyer, 2014, Journal of molecular and cellular cardiology.

Signalling pathways that mediate skeletal muscle hypertrophy and atrophy

D. Glass, 2003, Nature Cell Biology.

ARDD 2020: from aging mechanisms to interventions

S. Horvath, L. Ferrucci, Kai-Fu Lee, 2020, Aging.

Genomic and Proteomic Profiling Reveals Reduced Mitochondrial Function and Disruption of the Neuromuscular Junction Driving Rat Sarcopenia

S. Gygi, Yunyu Zhang, S. Brachat, 2012, Molecular and Cellular Biology.

Treating cancer cachexia to treat cancer

D. Glass, Se-Jin Lee, 2011, Skeletal Muscle.

Hepatocyte Growth Factor Promotes Motor Neuron Survival and Synergizes with Ciliary Neurotrophic Factor*

G. Yancopoulos, D. Glass, G. Conn, 1997, The Journal of Biological Chemistry.

Conserved sequences and transcription of the hsp70 gene family in Trypanosoma brucei

D. Glass, L. V. D. van der Ploeg, R. I. Polvere, 1986, Molecular and cellular biology.

Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins.

Holly McDonough, C. Patterson, D. Glass, 2007, The Journal of clinical investigation.

Clinical Classification of Cancer Cachexia: Phenotypic Correlates in Human Skeletal Muscle

C. Jacobi, S. Hatakeyama, J. Ross, 2014, PloS one.

Agrin and microvascular damage in Alzheimer's disease

M. Rafii, T. Berzin, G. Yancopoulos, 2000, Neurobiology of Aging.

Endogenous Muscle Atrophy F-Box Mediates Pressure Overload–Induced Cardiac Hypertrophy Through Regulation of Nuclear Factor-&kgr;B

D. Glass, Y. Maejima, J. Sadoshima, 2011, Circulation research.

Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells.

W. Evans, M. Fornaro, D. Glass, 2014, American journal of physiology. Endocrinology and metabolism.

Signaling pathways perturbing muscle mass

D. Glass, 2010, Current opinion in clinical nutrition and metabolic care.

Conditional Activation of Akt in Adult Skeletal Muscle Induces Rapid Hypertrophy

G. Yancopoulos, D. Glass, A. Economides, 2004, Molecular and Cellular Biology.

The Activin/FLRG Pathway Associates with Poor COVID-19 Outcomes in Hospitalized Patients

C. Kyratsous, D. Glass, A. Boyapati, 2021, Molecular and cellular biology.

Tissue-specific alternative splicing generates two isoforms of the trkA receptor.

E. Shooter, S. Meakin, P. Barker, 1993, The Journal of biological chemistry.

Cardiac sympathetic neurons provide trophic signal to the heart via β2-adrenoceptor-dependent regulation of proteolysis.

M. Mongillo, M. Sandri, E. Bertaggia, 2013, Cardiovascular research.

Skeletal muscle in MuRF1 null mice is not spared in low-gravity conditions, indicating atrophy proceeds by unique mechanisms in space

L. Stodieck, Yunyu Zhang, S. Brachat, 2019, Scientific Reports.

Gαi2 Signaling Promotes Skeletal Muscle Hypertrophy, Myoblast Differentiation, and Muscle Regeneration

M. Fornaro, D. Glass, A. Sailer, 2011, Science Signaling.

Blockade of Metallothioneins 1 and 2 Increases Skeletal Muscle Mass and Strength

D. Glass, B. Fournier, S. Gutzwiller, 2016, Molecular and Cellular Biology.

ATP Citrate Lyase Regulates Myofiber Differentiation and Increases Regeneration by Altering Histone Acetylation.

M. Fornaro, D. Glass, F. Morvan, 2017, Cell reports.

HDAC4 Controls Muscle Homeostasis through Deacetylation of Myosin Heavy Chain, PGC-1α, and Hsc70.

D. Glass, A. Trendelenburg, Huili Zhai, 2019, Cell reports.

Muscle ring finger 1 and muscle ring finger 2 are necessary but functionally redundant during developmental cardiac growth and regulate E2F1‐mediated gene expression in vivo

J. Schisler, Eleanor G. Hilliard, C. Patterson, 2014, Cell biochemistry and function.

Insulin-like Growth Factor-1 ( IGF-1 ) Inversely Regulates Atrophy-induced Genes via the Phosphatidylinositol 3-Kinase / Akt / Mammalian Target of Rapamycin ( PI 3 K / Akt / mTOR ) Pathway *

Hsin C. Lin, Francis J. Martin, Yi Wei, 2005 .

Deletion of atrophy enhancing genes fails to ameliorate the phenotype in a mouse model of spinal muscular atrophy

C. Iyer, D. Glass, V. McGovern, 2014, Neuromuscular Disorders.

MNK2 Inhibits eIF4G Activation Through a Pathway Involving Serine-Arginine–Rich Protein Kinase in Skeletal Muscle

Sherry Chin, D. Glass, Shanchuan Zhao, 2012, Science Signaling.

Se-Jin Lee, myostatin discoverer, elected to the National Academy of Science

B. Spiegelman, D. Glass, 2012, Skeletal Muscle.

Localization and regulation of MuSK at the neuromuscular junction.

P. Distefano, G. Yancopoulos, S. Bodine, 1998, Developmental biology.

The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors.

G. Yancopoulos, D. Glass, B. A. Clarke, 2004, Molecular cell.

Developmental expression and upregulation of muscle-specific kinase (MuSK) in denervated skeletal muscle of the chick and rat

G. Yancopoulos, N. Ip, D. Glass, 1996 .

Alterations in the in vitro and in vivo regulation of muscle regeneration in healthy ageing and the influence of sarcopenia

C. Jacobi, J. Ross, Alain Schilb, 2017, Journal of cachexia, sarcopenia and muscle.

Welcome to Skeletal Muscle

M. Rudnicki, K. Campbell, D. Glass, 2011, Skeletal Muscle.

Muscle RING‐finger 2 and 3 maintain striated‐muscle structure and function

G. Dittmar, E. Olson, R. Bassel-Duby, 2015, Journal of cachexia, sarcopenia and muscle.

Protein signatures of centenarians and their offspring suggest centenarians age slower than other humans

Toshiko Tanaka, L. Ferrucci, P. Sebastiani, 2019, Aging cell.

Supraphysiologic Administration of GDF11 Induces Cachexia in Part by Upregulating GDF15.

D. Glass, Juli E Jones, Chenguang Gong, 2018, Cell reports.

α-Dystrobrevin-1 recruits Grb2 and α-catulin to organize neurotransmitter receptors at the neuromuscular junction

J. Sanes, D. Glass, T. Prószyński, 2016, Journal of Cell Science.

Activin A correlates with the worst outcomes in COVID-19 patients, and can be induced by cytokines via the IKK/NF-kappa B pathway

C. Kyratsous, D. Glass, A. Boyapati, 2021, bioRxiv.

IKKbeta/NF-kappaB activation causes severe muscle wasting in mice.

W. Frontera, S. Shoelson, H. Lidov, 2004, Cell.

Genetic Deletion of Trb3, the Mammalian Drosophila tribbles Homolog, Displays Normal Hepatic Insulin Signaling and Glucose Homeostasis

A. Murphy, H. Okamoto, G. Yancopoulos, 2007, Diabetes.

Distinct phenotypes of mutant mice lacking agrin, MuSK, or rapsyn.

G. Yancopoulos, D. Glass, T. Dechiara, 1999, Brain research. Developmental brain research.

Elevated GDF11 Is a Risk Factor for Age-Related Frailty and Disease in Humans.

D. Glass, 2016, Cell metabolism.

Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways

C. Rommel, G. Yancopoulos, S. Bodine, 2001, Nature Cell Biology.

Cloning and analysis of neurotrophic factor receptors using function-based strategies.

N. Ip, D. Glass, M. Goldfarb, 1992, Cold Spring Harbor symposia on quantitative biology.

Short-term Low-Dose mTORC1 Inhibition in Aged Rats Counter-Regulates Age-Related Gene Changes and Blocks Age-Related Kidney Pathology

M. Egerman, D. Glass, T. Shavlakadze, 2018, The journals of gerontology. Series A, Biological sciences and medical sciences.

Skeletal Muscle - one year on

M. Rudnicki, K. Campbell, D. Glass, 2012, Skeletal Muscle.

The Receptor Tyrosine Kinase MuSK Is Required for Neuromuscular Junction Formation In Vivo

P. Distefano, G. Yancopoulos, D. Glass, 1996, Cell.

A critique of the hypothesis, and a defense of the question, as a framework for experimentation.

D. Glass, David J Glass, 2010, Clinical chemistry.

Rapsyn Is Required for MuSK Signaling and Recruits Synaptic Components to a MuSK-Containing Scaffold

J. Sanes, G. Yancopoulos, D. Glass, 1997, Neuron.

Agrin Acts via a MuSK Receptor Complex

P. Distefano, G. Yancopoulos, C. Radziejewski, 1996, Cell.

Cancer cachexia: mediators, signaling, and metabolic pathways.

D. Glass, D. Guttridge, K. Fearon, 2012, Cell metabolism.

Laminin-induced Acetylcholine Receptor Clustering: An Alternative Pathway

G. Yancopoulos, D. Glass, Z. Hall, 1997, The Journal of cell biology.

Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3.

Mi-Sung Kim, E. Olson, R. Bassel-Duby, 2007, The Journal of clinical investigation.

Distinct Domains of Musk Mediate Its Abilities to Induce and to Associate with Postsynaptic Specializations

J. Sanes, G. Yancopoulos, D. Glass, 1999, The Journal of cell biology.

Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity

G. Yancopoulos, M. Sleeman, S. Wiegand, 2005, Nature Medicine.

A long non-coding RNA, LncMyoD, regulates skeletal muscle differentiation by blocking IMP2-mediated mRNA translation.

I. Clay, Yunyu Zhang, D. Glass, 2015, Developmental cell.

Exome-wide association studies in general and long-lived populations identify genetic variants related to human age

Alexander Hanbo Li, D. Ledbetter, D. Rader, 2020, bioRxiv.

An HMGA2-IGF2BP2 axis regulates myoblast proliferation and myogenesis.

Yunyu Zhang, M. Goddeeris, K. Campbell, 2012, Developmental cell.

Oncogenic NRAS, required for pathogenesis of embryonic rhabdomyosarcoma, relies upon the HMGA2-IGF2BP2 pathway.

Yunyu Zhang, D. Kirsch, D. Glass, 2013, Cancer research.

An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors.

G. Yancopoulos, C. Radziejewski, D. Glass, 1997, Molecular cell.

TORC1 inhibition enhances immune function and reduces infections in the elderly

M. Beibel, D. Glass, T. Shavlakadze, 2018, Science Translational Medicine.

mTOR inhibition improves immune function in the elderly

J. Praestgaard, J. Kovarik, H. Maecker, 2014, Science Translational Medicine.

IKKβ/NF-κB Activation Causes Severe Muscle Wasting in Mice

W. Frontera, S. Shoelson, H. Lidov, 2004, Cell.

Receptor tyrosine kinase specific for the skeletal muscle lineage: Expression in embryonic muscle, at the neuromuscular junction, and after injury

P. Distefano, M. L. Beau, N. Copeland, 1995, Neuron.

Blockade of the Activin Receptor IIB Activates Functional Brown Adipogenesis and Thermogenesis by Inducing Mitochondrial Oxidative Metabolism

S. Brachat, S. Hatakeyama, E. Persohn, 2012, Molecular and Cellular Biology.

Stefan Mitochondrial Oxidative Metabolism and Thermogenesis by Inducing Activates Functional Brown Adipogenesis Blockade of the Activin Receptor IIB

S. Brachat, S. Hatakeyama, E. Persohn, 2012 .

D. Glass, T. Shavlakadze, G. Roma, 2019, Cell reports.

Trkl3 mediates BDNF/NT-3-dependent survival and proliferation in fibroblasts lacking the low affinity NGF receptor

G. Yancopoulos, D. Glass, M. Goldfarb, 1991, Cell.

trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor

P. Distefano, G. Yancopoulos, C. Radziejewski, 1991, Cell.

Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy

D J Glass, G. Yancopoulos, Z. Pan, 2001, Science.

Pan-neurotrophin 1: a genetically engineered neurotrophic factor displaying multiple specificities in peripheral neurons in vitro and in vivo.

D. Glass, L. Ilag, C. Ibáñez, 1995, Proceedings of the National Academy of Sciences of the United States of America.

The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases

Pamela F. Jones, Greg Lemke, P. Distefano, 1995, Cell.

Sorbs1 and -2 Interact with CrkL and Are Required for Acetylcholine Receptor Cluster Formation

Sherry Chin, D. Glass, S. Blais, 2015, Molecular and Cellular Biology.

The low affinity NGF receptor, p75, can collaborate with each of the Trks to potentiate functional responses to the neurotrophins

G. Yancopoulos, D. Glass, M. Goldfarb, 1994, Neuron.

The neurotrophins and their receptors.

G. Yancopoulos, D. Glass, David J. Glass, 1993, Trends in cell biology.

Alternative forms of rat TrkC with different functional capabilities

G. Yancopoulos, N. Ip, D. Glass, 1993, Neuron.

L. Greene, M. Barbacid, G. Yancopoulos, 1993, Neuron.

Naturally Occurring Tyrosine Kinase Inserts Block High Affinity Binding of Phospholipase Cγ and Shc to TrkC and Neurotrophin-3 Signaling (*)

G. Yancopoulos, J. Tavaré, D. Glass, 1995, The Journal of Biological Chemistry.

K-252a and staurosporine selectively block autophosphorylation of neurotrophin receptors and neurotrophin-mediated responses.

G. Yancopoulos, N. Ip, D. Glass, 1992, Molecular biology of the cell.

Activin type II receptor signaling in cardiac aging and heart failure

Vassilios J. Bezzerides, N. Houstis, J. Seidman, 2019, Science Translational Medicine.

Skeletal muscle in MuRF1 null mice is not spared in low-gravity conditions, indicating atrophy proceeds by unique mechanisms in space

L. Stodieck, Yunyu Zhang, S. Brachat, 2019, Scientific Reports.

ATP citrate lyase improves mitochondrial function in skeletal muscle.

M. Fornaro, D. Glass, F. Morvan, 2015, Cell metabolism.

The ubiquitin ligase MuRF1 regulates PPARα activity in the heart by enhancing nuclear export via monoubiquitination

D. Lalush, C. Newgard, J. Schisler, 2015, Molecular and Cellular Endocrinology.

Sequential roles of agrin, MuSK and rapsyn during neuromuscular junction formation

G. Yancopoulos, D. Glass, 1997, Current Opinion in Neurobiology.

TAK-1/p38/nNFκB signaling inhibits myoblast differentiation by increasing levels of Activin A

C. Jacobi, D. Glass, J. Feige, 2012, Skeletal Muscle.

αKlotho Regulates Age-Associated Vascular Calcification and Lifespan in Zebrafish.

M. Fishman, D. Glass, A. Singh, 2019, Cell reports.

mTORC1 and PKB/Akt control the muscle response to denervation by regulating autophagy and HDAC4

Shuo Lin, D. Glass, M. Rüegg, 2019, Nature Communications.

A serum protein signature of APOE genotypes in centenarians

L. Ferrucci, P. Sebastiani, S. Monti, 2019, Aging cell.

Partial Inhibition of mTORC1 in Aged Rats Counteracts the Decline in Muscle Mass and Reverses Molecular Signaling Associated with Sarcopenia

D. Glass, T. Shavlakadze, H. Tse, 2019, Molecular and Cellular Biology.

The E3 Ligase MuRF1 degrades myosin heavy chain protein in dexamethasone-treated skeletal muscle.

S. Rakhilin, C. Patterson, D. Glass, 2007, Cell metabolism.

Protein kinase A activation inhibits DUX4 gene expression in myotubes from patients with facioscapulohumeral muscular dystrophy

Yunyu Zhang, Y. Wang, D. Glass, 2018, The Journal of Biological Chemistry.

Loss of oxidative defense and potential blockade of satellite cell maturation in the skeletal muscle of patients with cancer but not in the healthy elderly

C. Jacobi, J. Ross, Alain Schilb, 2016, Aging.

Recent advances in the biology and therapy of muscle wasting

R. Roubenoff, D. Glass, 2010, Annals of the New York Academy of Sciences.

A signaling role for dystrophin: inhibiting skeletal muscle atrophy pathways.

D. Glass, 2005, Cancer cell.

Conditional Activation of MET in Differentiated Skeletal Muscle Induces Atrophy*

C. Scuoppo, Jennifer S Griffiths, R. Taulli, 2007, Journal of Biological Chemistry.

Gαi2 Signaling Is Required for Skeletal Muscle Growth, Regeneration, and Satellite Cell Proliferation and Differentiation

L. Birnbaumer, M. Fornaro, D. Glass, 2013, Molecular and Cellular Biology.

Variant surface glycoprotein gene expression site switches in Trypanosoma brucei.

D. Glass, S. Parangi, L. V. D. van der Ploeg, 1986, The Journal of biological chemistry.

TORC1 inhibition as an immunotherapy to reduce infections in the elderly

M. Beibel, D. Glass, T. Shavlakadze, 2017, bioRxiv.

Reply: Calcineurin and skeletal muscle growth

G. Yancopoulos, D. Glass, 2002, Nature Cell Biology.

Muscle ring finger 1 mediates cardiac atrophy in vivo.

Cam Patterson, Craig H Selzman, C. Patterson, 2009, American journal of physiology. Heart and circulatory physiology.

Muscle Ring Finger 1, but not Muscle Ring Finger 2, Regulates Cardiac Hypertrophy In Vivo

Cam Patterson, Monte S. Willis, Da-Zhi Wang, 2007, Circulation research.

What's So Special about FGF19-Unique Effects Reported on Skeletal Muscle Mass and Function.

D. Glass, 2017, Cell metabolism.

Agrin and microvascular damage in Alzheimer’s disease

M. Rafii, T. Berzin, G. Yancopoulos, 2000, Neurobiology of Aging.

Agrin in Alzheimer's Disease: Altered Solubility and Abnormal Distribution within Microvasculature and Brain Parenchyma

M. Rafii, T. Berzin, G. Yancopoulos, 1999 .

Dual roles of mTORC1-dependent activation of the ubiquitin-proteasome system in muscle proteostasis

M. Zavolan, D. Glass, L. Tintignac, 2021, bioRxiv.

Safety, tolerability, and preliminary efficacy of an IGF-1 mimetic in patients with spinal and bulbar muscular atrophy: a randomised, placebo-controlled trial

K. Fischbeck, B. Minton, A. Ludolph, 2018, The Lancet Neurology.

D. Glass, T. Shavlakadze, G. Roma, 2019, bioRxiv.

The receptor tyrosine kinase MuSK is required for neuromuscular junction formation and is a functional receptor for agrin.

P. Distefano, G. Yancopoulos, D. Glass, 1996, Cold Spring Harbor symposia on quantitative biology.

Functional analysis of mutant neurotrophins deficient in low‐affinity binding reveals a role for p75LNGFR in NT‐4 signalling.

G. Yancopoulos, J. Murray-Rust, D. Glass, 1995, The EMBO journal.

G. Atwal, M. Ni, Yi Wei, 2023, Skeletal Muscle.

ConneCting the Community of patients, families, CliniCians and investigators

L. Kunkel, K. Mathews, D. Glass, 2015 .

MG53′s new identity

K. Campbell, D. Glass, Jennifer R. Levy, 2013, Skeletal Muscle.

Protein signatures of centenarians and their offspring suggest centenarians age slower than other humans

L. Ferrucci, P. Sebastiani, S. Monti, 2021, Aging cell.

Inhibition of mTORC1 signaling in aged rats counteracts the decline in muscle mass and reverses multiple parameters of muscle signaling associated with sarcopenia

D. Glass, T. Shavlakadze, H. Tse, 2019, bioRxiv.

MAFbx/Atrogin-1 is required for atrophic remodeling of the unloaded heart.

O. Frazier, D. Glass, H. Taegtmeyer, 2014, Journal of molecular and cellular cardiology.

The SCF-Fbxo40 complex induces IRS1 ubiquitination in skeletal muscle, limiting IGF1 signaling.

D. Glass, Jun Shi, C. Ibebunjo, 2011, Developmental cell.

Faculty Opinions recommendation of Dystrophin glycoprotein complex dysfunction: a regulatory link between muscular dystrophy and cancer cachexia.

D. Glass, 2016 .

Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins

Holly McDonough, C. Patterson, D. Glass, 2022, The Journal of clinical investigation.

Molecular mechanisms and treatment options for muscle wasting diseases.

D. Glass, M. Rüegg, 2011, Annual review of pharmacology and toxicology.

Dealing with Consequences of Irreproducibility and Modifying the Published Literature: Retractions versus Revisions.

J. Flier, D. Glass, 2017, Cell metabolism.

What's So Special about FGF19-Unique Effects Reported on Skeletal Muscle Mass and Function.

D. Glass, 2017, Cell metabolism.

Science Signaling Podcast: 27 March 2012

D. Glass, A. VanHook, 2012, Science Signaling.