Z. Qin

Z. Qin, Mei Li, Wei Zhang, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

New horizon in autophagy research

Z. Qin, W. Le, 2013, Acta Pharmacologica Sinica.

History and Current Status of Autophagy Research.

Z. Qin, Rui Sheng, Zheng-Hong Qin, 2019, Advances in experimental medicine and biology.

TIGAR contributes to ischemic tolerance induced by cerebral preconditioning through scavenging of reactive oxygen species and inhibition of apoptosis

Dan-dan Song, Z. Qin, Rui Sheng, 2016, Scientific Reports.

Differential Effects of Naja naja atra Venom on Immune Activity

Z. Qin, Rong Han, Shu-Zhi Wang, 2014, Evidence-based complementary and alternative medicine : eCAM.

Activated cathepsin L is associated with the switch from autophagy to apoptotic death of SH-SY5Y cells exposed to 6-hydroxydopamine.

Z. Qin, Zhongqin Liang, Yun-zhen Song, 2016, Biochemical and biophysical research communications.

DY-9760e inhibits endothelin-1-induced cardiomyocyte hypertrophy through inhibition of CaMKII and ERK activities.

K. Fukunaga, Z. Qin, N. Shioda, 2009, Cardiovascular therapeutics.

Melatonin ameliorates hypoglycemic stress‐induced brain endothelial tight junction injury by inhibiting protein nitration of TP53‐induced glycolysis and apoptosis regulator

K. Fukunaga, Z. Qin, F. Han, 2017, Journal of pineal research.

Nuclear factor-kappa B contributes to excitotoxin-induced apoptosis in rat striatum.

T. Chase, Z. Qin, Y. Wang, 1998, Molecular pharmacology.

Regulation of c‐Jun N‐terminal kinase, p38 kinase and AP‐1 DNA binding in cultured brain neurons: roles in glutamate excitotoxicity and lithium neuroprotection

D. Chuang, Z. Qin, P. Leeds, 2003, Journal of neurochemistry.

Endoplasmic reticulum chaperone GRP78 is involved in autophagy activation induced by ischemic preconditioning in neural cells

Dan-dan Song, Z. Qin, Rui Sheng, 2015, Molecular Brain.

Could NF-κB and caspase-3 be markers for estimation of post-interval of human traumatic brain injury?

Z. Qin, Xi-ping Chen, L. Tao, 2006 .

Protective effect of Ginkgolids (A+B) is associated with inhibition of NIK/IKK/IκB/NF-κB signaling pathway in a rat model of permanent focal cerebral ischemia

S. Savitz, Z. Qin, Huiling Zhang, 2008, Brain Research.

Cathepsin L Plays a Role in Quinolinic Acid-Induced NF-Κb Activation and Excitotoxicity in Rat Striatal Neurons

Z. Qin, Jun-chao Wu, Zhong-Qin Liang, 2013, PloS one.

Preservation of Cognitive Function by Lepidium meyenii (Maca) Is Associated with Improvement of Mitochondrial Activity and Upregulation of Autophagy-Related Proteins in Middle-Aged Mouse Cortex

Z. Qin, Z. Wan, Li Luo, 2016, Evidence-based complementary and alternative medicine : eCAM.

Caspase-1 inhibitor Ac-YVAD-CHO attenuates quinolinic acid-induced increases in p53 and apoptosis in rat striatum

Z. Qin, Fang Lin, Rong Han, 2005, Acta Pharmacologica Sinica.

Beclin 1, Bcl-2 and Autophagy.

Z. Qin, Hai-dong Xu, Zheng-Hong Qin, 2019, Advances in experimental medicine and biology.

Neuroprotective effects of prostaglandin A1 in animal models of focal ischemia

T. Chase, Z. Qin, Rong Han, 2005, Brain Research.

Syntaxin 17 inhibits ischemic neuronal injury by resuming autophagy flux and ameliorating endoplasmic reticulum stress.

Z. Qin, Zhong Chen, Rui Sheng, 2020, Free radical biology & medicine.

RRx-001 Exerts Neuroprotection Against LPS-Induced Microglia Activation and Neuroinflammation Through Disturbing the TLR4 Pathway

Z. Qin, Jun-chao Wu, Fang Lin, 2022, Frontiers in Pharmacology.

A long-form α-neurotoxin from cobra venom produces potent opioid-independent analgesia

Z. Qin, Rong Han, Z. Gu, 2006, Acta Pharmacologica Sinica.

TIGAR inhibits ischemia/reperfusion-induced inflammatory response of astrocytes

Z. Qin, Zhong Chen, Jian Wang, 2018, Neuropharmacology.

High intensity interval training induces dysregulation of mitochondrial respiratory complex and mitophagy in the hippocampus of middle-aged mice

Z. Qin, Guiping Wang, Li Luo, 2021, Behavioural Brain Research.

Ischemia/reperfusion-induced upregulation of TIGAR in brain is mediated by SP1 and modulated by ROS and hormones involved in glucose metabolism

Z. Qin, F. Han, Jinghua Gu, 2015, Neurochemistry International.

Combined prostaglandin E1 and lithium exert potent neuroprotection in a rat model of cerebral ischemia

Z. Qin, Rui Sheng, Rong Han, 2011, Acta Pharmacologica Sinica.

Synergistic effects of prostaglandin E1 and lithium in a rat model of cerebral ischemia

Z. Qin, Rui Sheng, Rong Han, 2008, Acta Pharmacologica Sinica.

Effects of LY294002 on the invasiveness of human gastric cancer in vivo in nude mice.

Z. Qin, C. Xing, Bao-song Zhu, 2009, World journal of gastroenterology.

Enhancement of neuroprotection and heat shock protein induction by combined prostaglandin A1 and lithium in rodent models of focal ischemia

Z. Qin, Rong Han, Z. Gu, 2006, Brain Research.

Endogenous level of TIGAR in brain is associated with vulnerability of neurons to ischemic injury

Guanghui Wang, Z. Qin, F. Han, 2015, Neuroscience Bulletin.

Antinociceptive and Anti-Inflammatory Effects of Orally Administrated Denatured Naja Naja Atra Venom on Murine Rheumatoid Arthritis Models

Z. Qin, Yan-li Liu, Jin-Hua Gu, 2013, Evidence-based complementary and alternative medicine : eCAM.

Neuroprotective effects of prostaglandin A1 in rat models of permanent focal cerebral ischemia are associated with nuclear factor‐κB inhibition and peroxisome proliferator‐activated receptor‐γ up‐regulation

K. Fukunaga, S. Savitz, Z. Qin, 2008 .

Aescin-induced reactive oxygen species play a pro-survival role in human cancer cells via ATM/AMPK/ULK1-mediated autophagy

G. Wang, W. Dai, Z. Qin, 2018, Acta Pharmacologica Sinica.

Mechanisms of lysosomal proteases participating in cerebral ischemia-induced neuronal death

Z. Qin, Huiling Zhang, Ai-Ping Qin, 2008, Neuroscience bulletin.

Biomarkers of Autophagy.

Z. Qin, Fang Lin, Yu-ting Zhu, 2021, Advances in experimental medicine and biology.

Title Sphingosine kinase 2 activates autophagy and protects neurons against ischemic injury through interaction with Bcl-2 via its putative BH 3 domain

Dan-dan Song, Z. Qin, C. Waeber, 2019 .

Suppression of complete Freund's adjuvant-induced adjuvant arthritis by cobratoxin

Z. Qin, Jun-chao Wu, Yan-li Liu, 2009, Acta Pharmacologica Sinica.

Pro-caspase-8 Is Predominantly Localized in Mitochondria and Released into Cytoplasm upon Apoptotic Stimulation*

M. DiFiglia, K. Kikly, Z. Qin, 2001, The Journal of Biological Chemistry.

Therapeutic effect of SN50, an inhibitor of nuclear factor-κB, in treatment of TBI in mice

Z. Qin, Ran Liu, Xi-ping Chen, 2013, Neurological Sciences.

Exercise activates lysosomal function in the brain through AMPK‐SIRT1‐TFEB pathway

Z. Qin, Jun-chao Wu, Fang Lin, 2019, CNS neuroscience & therapeutics.

Preconditioning Stimuli Induce Autophagy via Sphingosine Kinase 2 in Mouse Cortical Neurons*

M. DiFiglia, Z. Qin, Charles D Smith, 2014, Journal of Biological Chemistry.

Involvement of cholinergic system in suppression of formalin-induced inflammatory pain by cobratoxin

Z. Qin, Yan-li Liu, P. Reid, 2011, Acta Pharmacologica Sinica.

Combination of NAD+ and NADPH Offers Greater Neuroprotection in Ischemic Stroke Models by Relieving Metabolic Stress

K. Fukunaga, Z. Qin, Jun-chao Wu, 2017, Molecular Neurobiology.

Combined NADPH and the NOX inhibitor apocynin provides greater anti‐inflammatory and neuroprotective effects in a mouse model of stroke

Z. Qin, F. Han, Jian Wang, 2017, Free radical biology & medicine.

Poloxamer 188 Protects Neurons against Ischemia/Reperfusion Injury through Preserving Integrity of Cell Membranes and Blood Brain Barrier

Z. Qin, Hai-dong Xu, Mei Li, 2013, PloS one.

The regulation of N-terminal Huntingtin (Htt552) accumulation by Beclin1

M. DiFiglia, Z. Qin, Jun-chao Wu, 2012, Acta Pharmacologica Sinica.

NADPH Protects against Kainic Acid-induced Excitotoxicity via Autophagy-lysosome Pathway in Rat Striatum and Primary Cortical Neurons.

Z. Qin, Jun-chao Wu, Zhong-Qin Liang, 2020, Toxicology.

Chronic stress impairs the aquaporin-4-mediated glymphatic transport through glucocorticoid signaling

Jian Song, Z. Qin, Guo-Xing Zhang, 2019, Psychopharmacology.

DRAM1 deficiency affects the organization and function of the Golgi apparatus.

Z. Qin, Jun-chao Wu, Yan Wang, 2019, Cellular signalling.

Prostaglandin A1 inhibits increases in intracellular calcium concentration, TXA2 production and platelet activation

Z. Qin, Zhong-Qin Liang, Z. Gu, 2006, Acta Pharmacologica Sinica.

Protective Effect of Nicotinamide Adenine Dinucleotide Phosphate on Renal Ischemia-Reperfusion Injury

Dan-dan Song, Yan Xie, Z. Qin, 2018, Kidney and Blood Pressure Research.

G6PD plays a neuroprotective role in brain ischemia through promoting pentose phosphate pathway.

Yuqiang Ding, Z. Qin, Zhong Chen, 2017, Free radical biology & medicine.

Triptolide inhibits NF-κB activation and reduces injury of donor lung induced by ischemia/reperfusion

Z. Qin, Jun-chao Wu, Jing-kang He, 2007, Acta Pharmacologica Sinica.

The role of p53 in cell metabolism

Z. Qin, Jin Wang, Xing-ding Zhang, 2010, Acta Pharmacologica Sinica.

Accumulation of beta-amyloid in the brain microvessels accompanies increased hyperphosphorylated tau proteins following microsphere embolism in aged rats

Z. Qin, N. Shioda, F. Han, 2008, Neuroscience.

Molecular and cellular mechanisms of excitotoxic neuronal death

Z. Qin, Yan Wang, Zheng-Hong Qin, 2010, Apoptosis.

Cathepsin B contributes to traumatic brain injury‐induced cell death through a mitochondria‐mediated apoptotic pathway

Z. Qin, Xi-ping Chen, L. Tao, 2010, Journal of neuroscience research.

Down‐regulation of Bcl‐2 enhances autophagy activation and cell death induced by mitochondrial dysfunction in rat striatum

K. Fukunaga, Z. Qin, Jun-chao Wu, 2009, Journal of neuroscience research.

An autophagic mechanism is involved in apoptotic death of rat striatal neurons induced by the non-N-methyl-D-aspartate receptor agonist kainic acid

Z. Qin, Jun-chao Wu, Zhong-Qin Liang, 2008, Autophagy.

Co-stimulation of cyclic-AMP-linked metabotropic glutamate receptors in rat striatum attenuates excitotoxin-induced nuclear factor-κB activation and apoptosis

T. Chase, D. Chuang, Z. Qin, 1999, Neuroscience.

Glutamate metabotropic receptor agonist 1S,3R-ACPD induces internucleosomal DNA fragmentation and cell death in rat striatum

T. Chase, Z. Qin, M. Nakai, 1997, Brain Research.

Autophagic and apoptotic mechanisms of curcumin-induced death in K562 cells

Z. Qin, Zhong-Qin Liang, Jun Li, 2009, Journal of Asian natural products research.

Free radical scavenger OPC-14117 attenuates quinolinic acid-induced NF-kappaB activation and apoptosis in rat striatum.

T. Chase, Z. Qin, Y. Wang, 1999, Brain Research. Molecular Brain Research.

Cobrotoxin could be an effective therapeutic for COVID-19

Z. Qin, Fang Lin, P. Reid, 2020, Acta Pharmacologica Sinica.

Effect of curcumin on the adhesion of platelets to brain microvascular endothelial cells in vitro

Z. Qin, Zhong-Qin Liang, Z. Gu, 2008, Acta Pharmacologica Sinica.

Transcription factor EB is involved in autophagy-mediated chemoresistance to doxorubicin in human cancer cells

Z. Qin, Hai-dong Xu, Quan-gen Gao, 2017, Acta Pharmacologica Sinica.

Analgesic effects of receptin, a chemically modified cobratoxin from Thailand cobra venom.

Z. Qin, Rong Han, Z. Gu, 2006, Neuroscience bulletin.

A short-chain alpha-neurotoxin from Naja naja atra produces potent cholinergic-dependent analgesia.

Z. Qin, Rong Han, Z. Gu, 2006, Neuroscience bulletin.

Structure, regulation, and biological functions of TIGAR and its role in diseases

Z. Qin, Rui Sheng, Lei Chen, 2021, Acta Pharmacologica Sinica.

TIGAR regulates DNA damage and repair through pentosephosphate pathway and Cdk5-ATM pathway

Z. Qin, Quan-gen Gao, Hao-rong Wu, 2015, Scientific Reports.

A TIGAR-Regulated Metabolic Pathway Is Critical for Protection of Brain Ischemia

Z. Qin, Yuan-yuan Qin, Rong Han, 2014, The Journal of Neuroscience.

In vivo administration of an oligodeoxynucleotide antisense to the D2 dopamine receptor messenger RNA inhibits D2 dopamine receptor-mediated behavior and the expression of D2 dopamine receptors in mouse striatum.

B. Weiss, Z. Qin, Zhen Qin, 1994, The Journal of pharmacology and experimental therapeutics.

The Role of TIGAR-mediated Metabolic Processes in Autophagy and Cell Survival

Z. Qin, Dingmei Zhang, Mei Li, 2020, Journal of Cellular Signaling.

TIGAR has a dual role in cancer cell survival through regulating apoptosis and autophagy.

Z. Qin, Wei Li, Quan-gen Gao, 2014, Cancer research.

The diverse role of TIGAR in cellular homeostasis and cancer

Z. Qin, Jun-chao Wu, Xiao Yuan, 2018, Free radical research.

TIGAR knockdown enhanced the anticancer effect of aescin via regulating autophagy and apoptosis in colorectal cancer cells

G. Wang, Z. Qin, Quan-gen Gao, 2018, Acta Pharmacologica Sinica.

Autophagy was activated in injured astrocytes and mildly decreased cell survival following glucose and oxygen deprivation and focal cerebral ischemia

Z. Qin, Jianqing Liu, Yuan-yuan Qin, 2010, Autophagy.

Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways

Feng Qi Han, K. Fukunaga, Z. Qin, 2008, Autophagy.

TP53-induced glycolysis and apoptosis regulator alleviates hypoxia/ischemia-induced microglial pyroptosis and ischemic brain damage

Z. Qin, Gen Li, Xin Ding, 2020, Neural regeneration research.

Susceptibility of striatal neurons to excitotoxic injury correlates with basal levels of Bcl-2 and the induction of P53 and c-Myc immunoreactivity

T. Chase, D. Chuang, Z. Qin, 2005, Neurobiology of Disease.

p53 mediates mitochondria dysfunction-triggered autophagy activation and cell death in rat striatum

K. Fukunaga, Z. Qin, Jun-chao Wu, 2009, Autophagy.

LY294002 induces p53-dependent apoptosis of SGC7901 gastric cancer cells

Z. Qin, Zhong-Qin Liang, Fang Lin, 2008, Acta Pharmacologica Sinica.

LY 294002 induces p 53-dependent apoptosis of SGC 7901 gastric cancer cells 1

Z. Qin, Zhong-Qin Liang, Fang Lin, 2008 .

Autophagy and Its Possible Roles in Nervous System Diseases, Damage and Repair

N. Heintz, D. Rubinsztein, B. Ravikumar, 2005, Autophagy.

Strategies for short hairpin RNA delivery in cancer gene therapy

Z. Qin, Shouli Wang, Hui-hua Yao, 2009, Expert opinion on biological therapy.

Dysfunction of nucleus accumbens-1 activates cellular senescence and inhibits tumor cell proliferation and oncogenesis.

I. Shih, Jin-Ming Yang, L. Shantz, 2012, Cancer research.

Endogenous level of TIGAR in brain is associated with vulnerability of neurons to ischemic injury

Guanghui Wang, Z. Qin, F. Han, 2015, Neuroscience Bulletin.

Neuronal localization and modulation of the D2 dopamine receptor mRNA in brain of normal mice and mice lesioned with 6-hydroxydopamine

J. F. Chen, B. Weiss, Z. Qin, 1991, Neuropharmacology.

Lysosomal Proteolysis Is Associated With Exercise-Induced Improvement of Mitochondrial Quality Control in Aged Hippocampus

Z. Qin, Hai-dong Xu, Zhou Zhu, 2017, The journals of gerontology. Series A, Biological sciences and medical sciences.

Exercise ameliorates the detrimental effect of chloroquine on skeletal muscles in mice via restoring autophagy flux

Z. Qin, Fang Lin, Kai Chen, 2013, Acta Pharmacologica Sinica.

Chronic resistance training activates autophagy and reduces apoptosis of muscle cells by modulating IGF-1 and its receptors, Akt/mTOR and Akt/FOXO3a signaling in aged rats

Z. Qin, Yan Wang, Li Luo, 2013, Experimental Gerontology.

Autophagy regulates the processing of amino terminal huntingtin fragments.

L. Thompson, Z. Qin, N. Aronin, 2003, Human molecular genetics.

Nuclear Factor κB Nuclear Translocation Upregulates c-Myc and p53 Expression during NMDA Receptor-Mediated Apoptosis in Rat Striatum

T. Chase, D. Chuang, Z. Qin, 1999, The Journal of Neuroscience.

Escin-induced DNA damage promotes escin-induced apoptosis in human colorectal cancer cells via p62 regulation of the ATM/γH2AX pathway

Z. Qin, Xiao-Dong Yang, C. Xing, 2018, Acta Pharmacologica Sinica.

Huntingtin Is Present in the Nucleus, Interacts with the Transcriptional Corepressor C-terminal Binding Protein, and Represses Transcription*

J. Nevins, Z. Qin, N. Aronin, 2002, The Journal of Biological Chemistry.

Cobratoxin inhibits pain-evoked discharge of neurons in thalamic parafascicular nucleus in rats: involvement of cholinergic and serotonergic systems.

Z. Qin, Q. Yin, Xinghong Jiang, 2009, Toxicon : official journal of the International Society on Toxinology.

Huntingtin Associates with Acidic Phospholipids at the Plasma Membrane*

M. Hayden, W. Goldmann, Z. Qin, 2005, Journal of Biological Chemistry.

Huntingtin Bodies Sequester Vesicle-Associated Proteins by a Polyproline-Dependent Interaction

M. Hayden, E. Wanker, Z. Qin, 2004, The Journal of Neuroscience.

Coordination of autophagy with other cellular activities

Z. Qin, Yan Wang, Zheng-Hong Qin, 2013, Acta Pharmacologica Sinica.

Dynamic effects of autophagy on arsenic trioxide-induced death of human leukemia cell line HL60 cells

Z. Qin, Zhong-Qin Liang, Ya-ping Yang, 2008, Acta Pharmacologica Sinica.

A sphingosine kinase 2-mimicking TAT-peptide protects neurons against ischemia-reperfusion injury by activating BNIP3-mediated mitophagy

Z. Qin, C. Waeber, Rui Sheng, 2020, Neuropharmacology.

Poloxamer-188 Attenuates TBI-Induced Blood–Brain Barrier Damage Leading to Decreased Brain Edema and Reduced Cellular Death

Yu Gao, Z. Qin, Ran Liu, 2012, Neurochemical Research.

Autophagy is involved in traumatic brain injury-induced cell death and contributes to functional outcome deficits in mice

Z. Qin, Zhen Qin, Ziqin Zhao, 2011, Neuroscience.

Current understanding on the pathogenesis of polyglutamine diseases

Z. Qin, Fang Lin, Xiao-Hui He, 2010, Neuroscience bulletin.

NADPH Oxidases in the Central Nervous System: regional and cellular localization and the possible link to brain diseases.

Z. Qin, Rui Sheng, Jie Fang, 2021, Antioxidants & redox signaling.

A fatal chronic ketamine poisoning.

Z. Qin, Y. Tao, X. Chen, 2005, Journal of forensic sciences.

A caspase-3-like protease is involved in NF-kappaB activation induced by stimulation of N-methyl-D-aspartate receptors in rat striatum.

Z. Qin, Y. Wang, T. N. Chasea, 2000, Brain research. Molecular brain research.

NAC1 Modulates Sensitivity of Ovarian Cancer Cells to Cisplatin via Altering the HMGB1-Mediated Autophagic Response*

I. Shih, R. Patel, Jin-Ming Yang, 2011, Oncogene.

Prostaglandin A1 inhibits rotenone‐induced apoptosis in SH‐SY5Y cells

Yan Leng, Z. Qin, Y. Leng, 2002, Journal of neurochemistry.

Cobrotoxin from Naja naja atra Venom Ameliorates Adriamycin Nephropathy in Rats

Z. Qin, Shu-Zhi Wang, Jian-qun Kou, 2015, Evidence-based complementary and alternative medicine : eCAM.

Quality control system of the endoplasmic reticulum and related diseases.

Z. Qin, Jun-chao Wu, Zhong-Qin Liang, 2006, Acta biochimica et biophysica Sinica.

The Protective Effects of Cobra Venom from Naja naja atra on Acute and Chronic Nephropathy

Z. Qin, Rong Han, Shu-Zhi Wang, 2013, Evidence-based complementary and alternative medicine : eCAM.

Inflammatory mechanism in ischemic neuronal injury.

Z. Qin, Huiling Zhang, Ya-Dan Wen, 2006, Neuroscience bulletin.

Kainic Acid‐Induced Apoptosis in Rat Striatum Is Associated with Nuclear Factor‐κB Activation

Z. Qin, Yumei Wang, Thomas N. Chase, 2000, Journal of neurochemistry.

Rapamycin prevents the mutant huntingtin-suppressed GLT-1 expression in cultured astrocytes

Z. Qin, Jun-chao Wu, Jin Wang, 2012, Acta Pharmacologica Sinica.

Dopaminergic and glutamatergic blocking drugs differentially regulate glutamic acid decarboxylase mRNA in mouse brain.

B. Weiss, Z. Qin, S. -. Zhang, 1994, Brain research. Molecular brain research.

Animal models of Huntington's disease: implications in uncovering pathogenic mechanisms and developing therapies

Z. Qin, Lin-hui Wang, Zheng-Hong Qin, 2006, Acta Pharmacologica Sinica.

Imbalance between CaM kinase II and calcineurin activities impairs caffeine-induced calcium release in hypertrophic cardiomyocytes.

K. Fukunaga, Z. Qin, N. Shioda, 2007, Biochemical pharmacology.

Dual roles of NF-κB in cell survival and implications of NF-κB inhibitors in neuroprotective therapy

Z. Qin, L. Tao, Xin Chen, 2007, Acta Pharmacologica Sinica.

Long-term running exercise alleviates cognitive dysfunction in APP/PSEN1 transgenic mice via enhancing brain lysosomal function

Z. Qin, Jun-chao Wu, Yan Wang, 2021, Acta Pharmacologica Sinica.

A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation

Z. Qin, Dong Chen, Fen Wang, 2015, Autophagy.

Molecular mechanism and regulation of autophagy

Z. Qin, Zhong-Qin Liang, Ya-ping Yang, 2005, Acta Pharmacologica Sinica.

Autophagy: Biology and Diseases: Basic Science

Z. Qin, 2019, Advances in Experimental Medicine and Biology.

Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis

Z. Qin, N. Aronin, E. Sapp, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Reduced Nicotinamide Adenine Dinucleotide Phosphate, a Pentose Phosphate Pathway Product, Might Be a Novel Drug Candidate for Ischemic Stroke

Z. Qin, Jun-chao Wu, F. Han, 2016, Stroke.

NADPH is superior to NADH or edaravone in ameliorating metabolic disturbance and brain injury in ischemic stroke

Z. Qin, Jun-chao Wu, Zhong Chen, 2021, Acta Pharmacologica Sinica.

The neuroprotective mechanism of brain ischemic preconditioning

Z. Qin, Rui Sheng, Xiao-qian Liu, 2009, Acta Pharmacologica Sinica.

A long-form alpha-neurotoxin from cobra venom produces potent opioid-independent analgesia.

Z. Qin, Rong Han, Z. Gu, 2006, Acta pharmacologica Sinica.

Mutant Huntingtin Impairs Vesicle Formation from Recycling Endosomes by Interfering with Rab11 Activity

Kevin Fogarty, Lawrence M. Lifshitz, Clive Standley, 2009, Molecular and Cellular Biology.

DRAM1 regulates autophagy and cell proliferation via inhibition of the phosphoinositide 3-kinase-Akt-mTOR-ribosomal protein S6 pathway

Z. Qin, Jun-chao Wu, H. She, 2019, Cell Communication and Signaling.

DRAM 1 regulates autophagy and cell proliferation via inhibition of the phosphoinositide 3-kinase-Akt-mTOR-ribosomal protein S 6 pathway

Z. Qin, Jun-chao Wu, Haidong Xu, 2022 .

Andrographolide alleviates parkinsonism in MPTP-PD mice via targeting DRP1-mediated mitochondrial fission.

Qiang Xu, Z. Qin, Yang Sun, 2019, British journal of pharmacology.

Reduced nicotinamide adenine dinucleotide phosphate in redox balance and diseases: a friend or foe?

Z. Qin, Rui Sheng, Nirmala Koju, 2022, Acta Pharmacologica Sinica.

Neuroprotection of NAD+ and NBP against ischemia/reperfusion brain injury is associated with restoration of sirtuin-regulated metabolic homeostasis

Z. Qin, Kangshuai Wang, Rui Sheng, 2023, Frontiers in Pharmacology.

Antisense oligodeoxynucleotide inhibits D2 dopamine receptor-mediated behavior and D2 messenger RNA

B. Weiss, Z. Qin, L.-W. Zhou, 1993, Neuroscience.

Suppression of Inflammation and Arthritis by Orally Administrated Cardiotoxin from Naja naja atra

Z. Qin, Shu-Zhi Wang, Jian-qun Kou, 2015, Evidence-based complementary and alternative medicine : eCAM.

Exogenous NADPH ameliorates myocardial ischemia–reperfusion injury in rats through activating AMPK/mTOR pathway

Z. Qin, Rui Sheng, Jiang Zhu, 2019, Acta Pharmacologica Sinica.

NADPH ameliorates MPTP-induced dopaminergic neurodegeneration through inhibiting p38MAPK activation

Z. Qin, Jun-chao Wu, Zhou Zhu, 2019, Acta Pharmacologica Sinica.

Reduced Nicotinamide Adenine Dinucleotide Phosphate Inhibits MPTP-Induced Neuroinflammation and Neurotoxicity

Feng Qi Han, Z. Qin, Jun-chao Wu, 2018, Neuroscience.

Huntingtin processing in pathogenesis of Huntington disease.

Z. Qin, Z. Gu, Zheng-Hong Qin, 2004, Acta pharmacologica Sinica.

DRAM1 plays a tumor suppressor role in NSCLC cells by promoting lysosomal degradation of EGFR

Z. Qin, Jun-chao Wu, Haidong Xu, 2020, Cell Death & Disease.

Inhibitory effect of crotoxin on the pain-evoked discharge of neurons in thalamic parafascicular nucleus in rats.

Z. Qin, Q. Yin, Xinghong Jiang, 2008, Toxicon : official journal of the International Society on Toxinology.

Somatic autophagy of axonal mitochondria in ischemic neurons

Feng Qi Han, Z. Qin, Weiwei Hu, 2019, The Journal of cell biology.

Neuronal autophagy in cerebral ischemia

Z. Qin, Feng Xu, Jin-hua Gu, 2012, Neuroscience Bulletin.

Aescin-induced reactive oxygen species play a pro-survival role in human cancer cells via ATM/AMPK/ULK1-mediated autophagy

W. Dai, Z. Qin, Gang Wang, 2018, Acta Pharmacologica Sinica.

D2 dopamine receptor antisense oligodeoxynucleotide inhibits the synthesis of a functional pool of D2 dopamine receptors.

B. Weiss, Z. Qin, Y. Wang, 1995, Molecular pharmacology.

Lysosomal enzyme cathepsin B is involved in kainic acid-induced excitotoxicity in rat striatum

Z. Qin, Zhong-Qin Liang, Yan Wang, 2006, Brain Research.

Bilobalide inhibits 6-OHDA-induced activation of NF-κB and loss of dopaminergic neurons in rat substantia nigra

Z. Qin, Zhong-Qin Liang, Z. Gu, 2008, Acta Pharmacologica Sinica.

O-GlcNAcylation Reduces Ischemia-Reperfusion–Induced Brain Injury

Fei Liu, Khadija Iqbal, Z. Qin, 2017, Scientific Reports.

Combination of NAD+ and NADPH Offers Greater Neuroprotection in Ischemic Stroke Models by Relieving Metabolic Stress

K. Fukunaga, Z. Qin, Jun-chao Wu, 2018, Molecular Neurobiology.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Alleviation of ischemic brain injury by exercise preconditioning is associated with modulation of autophagy and mitochondrial dynamics in cerebral cortex of female aged mice

Z. Qin, Yuan-yuan Qin, Xun Luo, 2023, Experimental Gerontology.

Mitochondrial-derived damage-associated molecular patterns amplify neuroinflammation in neurodegenerative diseases

Na Liu, Z. Qin, Yan Wang, 2022, Acta Pharmacologica Sinica.

Differential effects of overexpression of wild-type and mutant human α-synuclein on MPP+-induced neurotoxicity in PC12 cells

Z. Qin, C. Mao, Chun-Feng Liu, 2008, Neuroscience Letters.

Dual roles of NF-kappaB in cell survival and implications of NF-kappaB inhibitors in neuroprotective therapy.

Z. Qin, L. Tao, Xin Chen, 2007, Acta pharmacologica Sinica.

Growth inhibitory effects and molecular mechanisms of crotoxin treatment in esophageal Eca-109 cells and transplanted tumors in nude mice

Yan Xie, Z. Qin, Jing-kang He, 2012, Acta Pharmacologica Sinica.

Anti-tumor activity of CrTX in human lung adenocarcinoma cell line A549

Yan Xie, Z. Qin, Jun-chao Wu, 2011, Acta Pharmacologica Sinica.

Regulation of striatal dopamine receptors by corticosterone: an in vivo and in vitro study.

S. Yajima, Z. Qin, U. D'Souza, 1999, Brain research. Molecular brain research.

NMDA and non-NMDA receptor-stimulated IκB-α degradation: differential effects of the caspase-3 inhibitor DEVD·CHO, ethanol and free radical scavenger OPC-14117

T. Chase, Z. Qin, M. Nakai, 2000, Brain Research.

Endoplasmic reticulum chaperone GRP78 is involved in autophagy activation induced by ischemic preconditioning in neural cells

Dan-dan Song, Z. Qin, Rui Sheng, 2015, Molecular Brain.

Irreversible blockade of D2 dopamine receptors by fluphenazine-N-mustard increases D2 dopamine receptor mRNA and proenkephalin mRNA and decreases D1 dopamine receptor mRNA and mu and delta opioid receptors in rat striatum

B. Weiss, Z. Qin, V. Aloyo, 1994, Neurochemistry International.

Dopamine receptor blockade increases dopamine D2 receptor and glutamic acid decarboxylase mRNAs in mouse substantia nigra.

B. Weiss, Z. Qin, 1994, European journal of pharmacology.

Stimulation of N-methyl-d-aspartate receptors induces apoptosis in rat brain

T. Chase, Z. Qin, Yumei Wang, 1996, Brain Research.

A function of huntingtin in guanine nucleotide exchange on Rab11

Z. Qin, S. Zeitlin, N. Aronin, 2008, Neuroreport.

DRAM1 regulates autophagy and cell proliferation via inhibition of the phosphoinositide 3-kinase-Akt-mTOR-ribosomal protein S6 pathway

Z. Qin, Jun-chao Wu, Haidong Xu, 2019, Cell Communication and Signaling.

The role of post-translational modifications of huntingtin in the pathogenesis of Huntington’s disease

Z. Qin, Yan Wang, Fang Lin, 2010, Neuroscience Bulletin.

Editorial: Beclin 1 and autophagy---in memory of Beth Levine (1960–2020)

Z. Qin, Jun-chao Wu, Haidong Xu, 2022, Frontiers in Cell and Developmental Biology.

Reduced nicotinamide adenine dinucleotide phosphate inhibits rat platelet aggregation and p38 phosphorylation.

Z. Qin, Jun-chao Wu, Rui Sheng, 2018, Thrombosis research.

Neuronal autophagy in cerebral ischemia

Z. Qin, Feng Xu, Jin-hua Gu, 2012, Neuroscience Bulletin.

O-GlcNAcylation Reduces Ischemia-Reperfusion–Induced Brain Injury

Z. Qin, Jianhua Shi, Chun-ling Dai, 2017, Scientific Reports.

Escin-induced DNA damage promotes escin-induced apoptosis in human colorectal cancer cells via p62 regulation of the ATM/γH2AX pathway

Z. Qin, Xiao-Dong Yang, C. Xing, 2018, Acta Pharmacologica Sinica.