R. Tammali

发表

Aldose reductase inhibition prevents colon cancer growth by restoring phosphatase and tensin homolog through modulation of miR-21 and FOXO3a.

Ashish Saxena, K. Ramana, S. Srivastava, 2013, Antioxidants & redox signaling.

Improved Therapeutic Window in BRCA-mutant Tumors with Antibody-linked Pyrrolobenzodiazepine Dimers with and without PARP Inhibition

R. Tammali, R. Raja, R. Herbst, 2018, Molecular Cancer Therapeutics.

Aldose reductase deficiency protects sugar-induced lens opacification in rats.

K. Ramana, S. Srivastava, R. Tammali, 2011, Chemico-biological interactions.

Rational design of chimeric antigen receptor T cells against glypican 3 decouples toxicity from therapeutic efficacy.

R. Tammali, N. Monks, Ashley A. Merlino, 2022, Cytotherapy.

Inhibition of aldose reductase prevents angiogenesis in vitro and in vivo

K. Ramana, S. Srivastava, R. Tammali, 2011, Angiogenesis.

Targeting aldose reductase for the treatment of cancer.

K. Ramana, S. Srivastava, R. Tammali, 2011, Current cancer drug targets.

Aldose Reductase Inhibitor, Fidarestat Prevents High-fat Diet-induced Intestinal Polyps in ApcMin/+ Mice.

K. Ramana, S. Srivastava, A. Saxena, 2017, Current cancer drug targets.

Inhibition of aldose reductase prevents lipopolysaccharide-induced inflammatory response in human lens epithelial cells.

K. Ramana, S. Srivastava, R. Tammali, 2006, Investigative ophthalmology & visual science.

Negative regulation of the protection of eIF2alpha phosphorylation activity by a unique acidic domain present at the N-terminus of p67.

R. Tammali, B. Datta, R. Datta, 2003, Experimental cell research.

Aldose Reductase Mediates the Lipopolysaccharide-induced Release of Inflammatory Mediators in RAW264.7 Murine Macrophages*

K. Ramana, S. Srivastava, R. Tammali, 2006, Journal of Biological Chemistry.

Aldose reductase mediates endotoxin-induced production of nitric oxide and cytotoxicity in murine macrophages.

K. Ramana, S. Srivastava, R. Tammali, 2007, Free radical biology & medicine.

Aldose reductase regulates growth factor-induced cyclooxygenase-2 expression and prostaglandin E2 production in human colon cancer cells.

K. Ramana, S. Srivastava, R. Tammali, 2006, Cancer research.

Aldose reductase inhibition suppresses azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice.

K. Ramana, S. Srivastava, A. Saxena, 2014, Cancer letters.

Inhibition of aldose reductase prevents colon cancer metastasis.

K. Ramana, S. Srivastava, A. Saxena, 2011, Carcinogenesis.

Aldose reductase inhibition suppresses oxidative stress-induced inflammatory disorders.

K. Ramana, S. Srivastava, A. Saxena, 2011, Chemico-biological interactions.

Inhibition of Aldose Reductase Prevents Growth Factor–Induced G1-S Phase Transition through the AKT/Phosphoinositide 3-Kinase/E2F-1 Pathway in Human Colon Cancer Cells

K. Ramana, S. Srivastava, R. Tammali, 2010, Molecular Cancer Therapeutics.

Aldose reductase regulates TNF-α-induced PGE2 production in human colon cancer cells

K. Ramana, S. Srivastava, R. Tammali, 2007 .

Aldose reductase regulates TNF-alpha-induced PGE2 production in human colon cancer cells.

K. Ramana, S. Srivastava, R. Tammali, 2007, Cancer letters.

Antitumor Activity of MEDI3726 (ADCT-401), a Pyrrolobenzodiazepine Antibody–Drug Conjugate Targeting PSMA, in Preclinical Models of Prostate Cancer

N. Bander, E. Corey, R. Tammali, 2018, Molecular Cancer Therapeutics.

A Monoclonal Antibody to ADAM17 Inhibits Tumor Growth by Inhibiting EGFR and Non–EGFR-Mediated Pathways

R. Hollingsworth, J. Friedman, R. Tammali, 2015, Molecular Cancer Therapeutics.

Aldose reductase-regulated tumor necrosis factor-alpha production is essential for high glucose-induced vascular smooth muscle cell growth.

K. Ramana, S. Srivastava, R. Tammali, 2007, Endocrinology.

Contribution of aldose reductase to diabetic hyperproliferation of vascular smooth muscle cells.

K. Ramana, S. Srivastava, R. Tammali, 2006, Diabetes.

Requirement of aldose reductase for the hyperglycemic activation of protein kinase C and formation of diacylglycerol in vascular smooth muscle cells.

B. Friedrich, K. Ramana, S. Srivastava, 2005, Diabetes.

Regulation of lens aldose reductase activity by nitric oxide.

K. Ramana, R. Tammali, A. Bhatnagar, 2005, Experimental eye research.

A Potent HER3 Monoclonal Antibody That Blocks Both Ligand-Dependent and -Independent Activities: Differential Impacts of PTEN Status on Tumor Response

R. Hollingsworth, Zhan Xiao, R. Tammali, 2016, Molecular Cancer Therapeutics.

Discovery and Development of MEDI7247, a Novel Pyrrolobenzodiazepine (PBD)-Based Antibody Drug Conjugate Targeting ASCT2, for Treating Hematological Cancers

E. Hurt, M. Rebelatto, R. Tammali, 2018, Blood.

Aldose Reductase Inhibition Prevents Hypoxia-induced Increase in Hypoxia-inducible Factor-1α (HIF-1α) and Vascular Endothelial Growth Factor (VEGF) by Regulating 26 S Proteasome-mediated Protein Degradation in Human Colon Cancer Cells*

Ashish Saxena, K. Ramana, S. Srivastava, 2011, The Journal of Biological Chemistry.

Aldose reductase deficiency in mice prevents azoxymethane-induced colonic preneoplastic aberrant crypt foci formation.

K. Ramana, S. Srivastava, R. Tammali, 2009, Carcinogenesis.

Aldose reductase regulates vascular smooth muscle cell proliferation by modulating G1/S phase transition of cell cycle.

K. Ramana, S. Srivastava, A. Saxena, 2010, Endocrinology.

Comparison of pyrrolobenzodiazepine dimer bis-imine versus mono-imine: DNA interstrand cross-linking, cytotoxicity, and antibody-drug conjugate efficacy and toxicity.

R. Tammali, J. Hartley, E. Rosfjord, 2022, Molecular Cancer Therapeutics.

Inhibition of aldose reductase prevents lipopolysaccharide-induced inflammatory response in human lens epithelial cells.

K. Ramana, S. Srivastava, R. Tammali, 2006, Investigative Ophthalmology and Visual Science.

Inhibition of Aldose Reductase Prevents Growth Factor–Induced G1-S Phase Transition through the AKT/Phosphoinositide 3-Kinase/E2F-1 Pathway in Human Colon Cancer Cells

K. Ramana, S. Srivastava, R. Tammali, 2010, Molecular Cancer Therapeutics.

A Monoclonal Antibody to ADAM17 Inhibits Tumor Growth by Inhibiting EGFR and Non–EGFR-Mediated Pathways

R. Hollingsworth, R. Tammali, C. Leow, 2015, Molecular Cancer Therapeutics.