Dou Liu

发表

Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signaling to suppress tumorigenesis

Steven P. Gygi, Yonghao Yu, John M Asara, 2013, Nature Cell Biology.

Inhibition of the mTORC2 and chaperone pathways to treat leukemia.

B. Su, Adam S. Lazorchak, Dou Liu, 2012, Blood.

Exit from Exit Resetting the Cell Cycle through Amn1 Inhibition of G Protein Signaling

Stephen J. Elledge, Takahiro Shirogane, Yanchang Wang, 2003, Cell.

Sin1/mTORC2 regulate B cell growth and metabolism by activating mTORC1 and Myc

Adam S. Lazorchak, Omotooke Arojo, Dou Liu, 2019, Cellular & Molecular Immunology.

p21 and p57 control muscle differentiation at the myogenin step

S. Elledge, J. Harper, Pumin Zhang, 1999 .

Sin1 regulates Treg‐cell development but is not required for T‐cell growth and proliferation

B. Su, Adam S. Lazorchak, Dou Liu, 2012, European journal of immunology.

Active mTORC2 Signaling in Naive T Cells Suppresses Bone Marrow Homing by Inhibiting CXCR4 Expression

B. Su, S. Kaech, Omotooke Arojo, 2018, The Journal of Immunology.

Author Correction: Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis

S. Gygi, J. Blenis, B. Su, 2019, Nature Cell Biology.

mTOR complex 2 regulates proper turnover of insulin receptor substrate-1 via the ubiquitin ligase subunit Fbw8.

B. Su, Dou Liu, E. Jacinto, 2012, Molecular cell.

MAP3K2-regulated intestinal stromal cells define a distinct stem cell niche

F. Ginhoux, Bin Zhou, R. Flavell, 2021, Nature.

Replication protein A-mediated recruitment and activation of Rad17 complexes

S. Elledge, L. Zou, Dou Liu, 2003, Proceedings of the National Academy of Sciences of the United States of America.

MEKK3 Regulates IFN-γ Production in T Cells through the Rac1/2-Dependent MAPK Cascades

B. Su, Xiaofang Wang, Dou Liu, 2011, The Journal of Immunology.

Cascades Cells through the Rac 1 / 2-Dependent MAPK Production in T γ MEKK 3 Regulates IFN

Xiaofang Wang, Dou Liu, Fan Zhang, 2011 .

Structure and vascular function of MEKK3–cerebral cavernous malformations 2 complex

B. Turk, B. Su, T. Boggon, 2015, Nature Communications.

SIN1/MIP1 Maintains rictor-mTOR Complex Integrity and Regulates Akt Phosphorylation and Substrate Specificity

J. Qin, B. Su, S. Jung, 2006, Cell.

TAK1 negatively regulates NF-κB and p38 MAP kinase activation in Gr-1+CD11b+ neutrophils.

B. Su, J. Cui, Dou Liu, 2012, Immunity.

mTOR Complex 2 Targets Akt for Proteasomal Degradation via Phosphorylation at the Hydrophobic Motif*

Adam S. Lazorchak, Dou Liu, W. Ouyang, 2011, The Journal of Biological Chemistry.

Regulation of the Bub2/Bfa1 GAP Complex by Cdc5 and Cell Cycle Checkpoints

S. Elledge, J. Qin, Dou Liu, 2001, Cell.

Protein Implicated in Nonsyndromic Mental Retardation Regulates Protein Kinase A (PKA) Activity

J. Qin, B. Su, S. Jung, 2012, The Journal of Biological Chemistry.

Sin1-mTORC2 suppresses rag and il7r gene expression through Akt2 in B cells.

D. Schatz, B. Su, W. Sessa, 2010, Molecular cell.

MEKK2 mediates an alternative β-catenin pathway that promotes bone formation

S. Gygi, R. Baron, M. Greenblatt, 2016, Proceedings of the National Academy of Sciences.

Metabolic regulation of T cell development by Sin1–mTORC2 is mediated by pyruvate kinase M2

Dou Liu, Qiang Zou, Bing Su, 2018, Journal of molecular cell biology.

Map3k2-Regulated Intestinal Stromal Cells (MRISC) Define a Distinct Sub-cryptic Stem Cell Niche for Damage Induced Wnt Agonist R-spondin1 Production

R. Flavell, Dou Liu, Hua-Bing Li, 2019, bioRxiv.

Protein implicated in nonsyndromic mental retardation regulates protein kinase A (PKA) activity.

J. Qin, B. Su, S. Jung, 2012, The Journal of biological chemistry.

DNA damage-induced activation of p53 by the checkpoint kinase Chk2.

S. Elledge, T. Mak, Y. Kong, 2000, Science.

Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms.

H. Wang, S. Elledge, M. Tetzlaff, 1999, Science.

p21(CIP1) and p57(KIP2) control muscle differentiation at the myogenin step.

S. Elledge, J. Harper, D. Liu, 1999, Genes & development.

Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signaling to suppress tumorigenesis

S. Gygi, J. Blenis, B. Su, 2013, Nature Cell Biology.

TAK1 negatively regulates NF-κB and p38 MAP kinase activation in Gr-1+CD11b+ neutrophils.

B. Su, J. Cui, Dou Liu, 2012, Immunity.

Sin1 Phosphorylation Impairs Mtorc2 Complex Integrity and Inhibits Downstream Akt Signaling to Suppress Tumorigenesis Sin1 Phosphorylation Impairs Mtorc2 Complex Integrity and Inhibits Downstream Akt Signaling to Suppress Tumorigenesis Nih Public Access Author Manuscript Introduction

S. Gygi, J. Blenis, Wenyi Wei, 2022 .

Pds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint function.

H. Wang, S. Elledge, J. Qin, 2001, Genes & development.

mTOR complex 2 regulates proper turnover of insulin receptor substrate-1 via the ubiquitin ligase subunit Fbw8.

B. Su, Dou Liu, E. Jacinto, 2012, Molecular cell.