S. Menon

发表

Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signaling to suppress tumorigenesis

Steven P. Gygi, Yonghao Yu, John M Asara, 2013, Nature Cell Biology.

Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome

N. Wei, S. Menon, N. Dohmae, 2008, BMC Biochemistry.

COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor–induced entry into the cell cycle from quiescence

Xing Wang Deng, Richard A Flavell, Hongbo Chi, 2007, Nature Immunology.

Perturbation of Cullin Deneddylation via Conditional Csn8 Ablation Impairs the Ubiquitin–Proteasome System and Causes Cardiomyocyte Necrosis and Dilated Cardiomyopathy in Mice

Jinbao Liu, N. Wei, S. Menon, 2011, Circulation research.

The COP9 Signalosome Inhibits p27kip1 Degradation and Impedes G1-S Phase Progression via Deneddylation of SCF Cul1

Xiping Wang, Xiaoming Yang, Karin Lykke-Andersen, 2002, Current Biology.

Mammalian DET1 Regulates Cul4A Activity and Forms Stable Complexes with E2 Ubiquitin-Conjugating Enzymes

X. Deng, N. Wei, S. Menon, 2007, Molecular and Cellular Biology.

Molecular targets and approaches to restore autophagy and lysosomal capacity in neurodegenerative disorders.

J. Bastien, S. Menon, B. Nyfeler, 2021, Molecular aspects of medicine.

Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways.

Derek W. Yecies, D. Yecies, A. Lipovsky, 2011, Cell metabolism.

Bile acid analogues are activators of pyrin inflammasome

Stephen M. Canham, Edmund M. Harrington, S. Menon, 2019, The Journal of Biological Chemistry.

Cell signalling: Nutrient sensing lost in cancer

B. Manning, S. Menon, Suchithra Menon, 2013, Nature.

Author Correction: Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis

S. Gygi, J. Blenis, B. Su, 2019, Nature Cell Biology.

Chronic Activation of mTOR Complex 1 Is Sufficient to Cause Hepatocellular Carcinoma in Mice

R. Bronson, D. Kwiatkowski, B. Manning, 2012, Science Signaling.

Spatial Control of the TSC Complex Integrates Insulin and Nutrient Regulation of mTORC1 at the Lysosome

L. Cantley, G. Hoxhaj, B. Manning, 2014, Cell.

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

John A. Tallarico, M. Schirle, Christopher J. Wilson, 2014, Nature Cell Biology.

Activation of a metabolic gene regulatory network downstream of mTOR complex 1.

Qicheng Ma, Clary B Clish, Regina K. Gorski, 2010, Molecular cell.

CSN1 inhibits c-Jun phosphorylation and down-regulates ectopic expression of JNK1

N. Wei, S. Menon, Yingchun Tong, 2011, Protein & Cell.

TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1.

P. Finan, D. Kwiatkowski, J. Asara, 2012, Molecular cell.

Common corruption of the mTOR signaling network in human tumors

B. Manning, S. Menon, Suchithra Menon, 2008, Oncogene.

Association of MTOR Mutations With Developmental Brain Disorders, Including Megalencephaly, Focal Cortical Dysplasia, and Pigmentary Mosaicism.

Beth K. Martin, Michael P. Morrissey, J. Shendure, 2016, JAMA neurology.

Purification of the COP9 signalosome from porcine spleen, human cell lines, and Arabidopsis thaliana plants.

V. Rubio, X. Deng, Xiping Wang, 2005, Methods in enzymology.

COP9 Signalosome Subunit Csn8 Is Involved in Maintaining Proper Duration of the G1 Phase*

X. Deng, C. Liu, N. Wei, 2013, The Journal of Biological Chemistry.

Disruption of the COP9 Signalosome Csn2 Subunit in Mice Causes Deficient Cell Proliferation, Accumulation of p53 and Cyclin E, and Early Embryonic Death

X. Deng, Karin Lykke-Andersen, N. Wei, 2003, Molecular and Cellular Biology.

An iron-dependent metabolic vulnerability underlies VPS34-dependence in RKO cancer cells

D. Wiederschain, M. Beibel, S. Menon, 2020, PloS one.