J. Shelton

发表

Mechanical Unloading Activates FoxO3 to Trigger Bnip3‐Dependent Cardiomyocyte Atrophy

G. Dorn, Dian J. Cao, Nan Jiang, 2013, Journal of the American Heart Association.

Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy

John M. Shelton, Samadrita Bhattacharyya, E. Olson, 2016, Science.

Control of muscle formation by the fusogenic micropeptide myomixer

Hui Li, Andres Ramirez-Martinez, E. Olson, 2017, Science.

Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo

Rick B. Vega, E. Olson, R. Bassel-Duby, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Activated glycogen synthase-3β suppresses cardiac hypertrophy in vivo

E. Olson, J. McAnally, J. Richardson, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Prevention of muscular dystrophy in mice by CRISPR/Cas9–mediated editing of germline DNA

E. Olson, J. McAnally, R. Bassel-Duby, 2014, Science.

Toll-like receptor 4 regulates early endothelial activation during ischemic acute kidney injury.

J. Richardson, J. Shelton, Xin J. Zhou, 2011, Kidney international.

Maladaptive role of IL-6 in ischemic acute renal failure.

J. Richardson, D. Jeyarajah, J. Shelton, 2005, Journal of the American Society of Nephrology : JASN.

Myogenin and Class II HDACs Control Neurogenic Muscle Atrophy by Inducing E3 Ubiquitin Ligases

E. Olson, R. Bassel-Duby, J. Richardson, 2010, Cell.

A Micropeptide Encoded by a Putative Long Noncoding RNA Regulates Muscle Performance

John M. Shelton, E. Olson, J. Liou, 2015, Cell.

Deletion of Hexose-6-phosphate Dehydrogenase Activates the Unfolded Protein Response Pathway and Induces Skeletal Myopathy*

Francesco Falciani, Nil Turan, F. Falciani, 2008, Journal of Biological Chemistry.

Histone deacetylases 1 and 2 regulate autophagy flux and skeletal muscle homeostasis in mice

Chad E. Grueter, E. Olson, R. Bassel-Duby, 2012, Proceedings of the National Academy of Sciences.

erythropoietin-dependent manner HIF-2{alpha} regulates murine hematopoietic development in an

J. Richardson, J. Shelton, O. Moe, 2011 .

HIF-2alpha regulates murine hematopoietic development in an erythropoietin-dependent manner.

J. Richardson, J. Shelton, M. Bennett, 2005, Blood.

Molecular characterization of two mammalian bHLH-PAS domain proteins selectively expressed in the central nervous system.

U. Francke, S. McKnight, D. Russell, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Myocyte Enhancer Factor 2 and Class II Histone Deacetylases Control a Gender-Specific Pathway of Cardioprotection Mediated by the Estrogen Receptor

E. Olson, E. van Rooij, J. Shelton, 2010, Circulation research.

Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo.

E. Olson, J. McAnally, J. Richardson, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor.

S. Kliewer, M. Downes, R. Yu, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Tulp3 Regulates Renal Cystogenesis by Trafficking of Cystoproteins to Cilia

F. Qian, J. Shelton, Saikat Mukhopadhyay, 2019, Current Biology.

Ischemia-reperfusion induces G-CSF gene expression by renal medullary thick ascending limb cells in vivo and in vitro.

D. Link, J. Richardson, D. Jeyarajah, 2004, American journal of physiology. Renal physiology.

Sec13 Regulates Expression of Specific Immune Factors Involved in Inflammation In Vivo

Lihi Shaulov, B. Fontoura, J. Shelton, 2015, Scientific Reports.

Temporal and spatial expression of liver receptor homologue‐1 (LRH‐1) during embryogenesis suggests a potential role in gonadal development

J. Richardson, J. Shelton, C. Mendelson, 2005, Developmental dynamics : an official publication of the American Association of Anatomists.

Successful transplantation in canines after long-term coronary sinus machine perfusion preservation of donor hearts.

M. Peltz, J. Shelton, M. Jessen, 2013, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

Requirement of protein kinase D1 for pathological cardiac remodeling

Mi-Sung Kim, E. Olson, R. Bassel-Duby, 2008, Proceedings of the National Academy of Sciences.

Identification of Acyloxyacyl Hydrolase, a Lipopolysaccharide- Detoxifying Enzyme, in the Murine Urinary Tract

J. Richardson, J. Shelton, R. Munford, 2004, Infection and Immunity.

Angiocrine IGFBP3 Spatially Coordinates IGF Signaling During Neonatal Cardiac Regeneration

J. Shelton, H. Sadek, M. Kinter, 2021, bioRxiv.

Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver[S]

J. Shelton, J. C. Perales, S. Burgess, 2012, Journal of Lipid Research.

Ataxia and Purkinje cell degeneration in mice lacking the CAMTA1 transcription factor

Chad E. Grueter, E. Olson, R. Bassel-Duby, 2014, Proceedings of the National Academy of Sciences.

Expression of LRH-1 and SF-1 in the mouse ovary: localization in different cell types correlates with differing function

D. Mangelsdorf, J. Repa, J. Richardson, 2003, Molecular and Cellular Endocrinology.

Normal Development and Fertility of Knockout Mice Lacking the Tumor Suppressor Gene LRP1b Suggest Functional Compensation by LRP1

R. Hammer, J. Sweatt, E. Weeber, 2004, Molecular and Cellular Biology.

A reevaluation of CD22 expression in human lung cancer.

Laurentiu M. Pop, Iliodora V. Pop, J. Minna, 2014, Cancer research.

Thymosin beta4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo.

Jeffrey E. Thatcher, D. Srivastava, J. DiMaio, 2009, Journal of molecular and cellular cardiology.

Factor-Cardiac Failure in Transgenic Mice With Myocardial Expression of Tumor Necrosis

R. Peshock, J. Shelton, B. Giroir, 1998 .

Essential Role of STAT 3 in Body Weight and Glucose Homeostasis

J. Richardson, G. Karsenty, J. Shelton, 2003 .

Genomic regions that mediate placental cell-specific and developmental regulation of human Cyp19 (aromatase) gene expression in transgenic mice.

J. Richardson, J. Shelton, C. Mendelson, 2005, Endocrinology.

Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice

R. Hammer, J. Richardson, J. Shelton, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Transcriptional regulation of aromatase in placenta and ovary

J. Richardson, J. Shelton, C. Mendelson, 2005, The Journal of Steroid Biochemistry and Molecular Biology.

Myosin Regulatory Light Chain Phosphorylation Attenuates Cardiac Hypertrophy*

J. Stull, J. Richardson, J. Shelton, 2008, Journal of Biological Chemistry.

Severe myopathy in mice lacking the MEF2/SRF-dependent gene leiomodin-3.

E. Olson, J. McAnally, R. Bassel-Duby, 2015, The Journal of clinical investigation.

Autoimmune epididymoorchitis is essential to the pathogenesis of male-specific spondylarthritis in HLA-B27-transgenic rats.

R. Hammer, K. Tung, J. Richardson, 2012, Arthritis and rheumatism.

Adiponectin protects against development of metabolic disturbances in a PCOS mouse model

J. Shelton, E. Stener-Victorin, I. Wernstedt Asterholm, 2017, Proceedings of the National Academy of Sciences.

Cardiac-Specific LIM Protein FHL2 Modifies the Hypertrophic Response to &bgr;-Adrenergic Stimulation

R. Bassel-Duby, J. Richardson, J. Shelton, 2001, Circulation.

Generation of FHL 2 Knockout Mice

J. Richardson, J. Shelton, B. Rothermel, 2001 .

Characterization of Mouse Short-chain Aldehyde Reductase (SCALD), an Enzyme Regulated by Sterol Regulatory Element-binding Proteins*

J. Richardson, J. Shelton, J. Goldstein, 2003, Journal of Biological Chemistry.

Trans-cranial opening of the blood-brain barrier in targeted regions using a stereotaxic brain atlas and focused ultrasound energy

Rajiv Chopra, J. Richardson, J. Shelton, 2014, Journal of therapeutic ultrasound.

Hair growth defects in Insig-deficient mice caused by cholesterol precursor accumulation and reversed by simvastatin.

J. Richardson, J. Shelton, J. Goldstein, 2010, The Journal of investigative dermatology.

Overexpression of pyruvate dehydrogenase kinase 4 in heart perturbs metabolism and exacerbates calcineurin-induced cardiomyopathy.

Robert A. Harris, S. Kliewer, R. Bassel-Duby, 2008, American journal of physiology. Heart and circulatory physiology.

Myomaker: A membrane activator of myoblast fusion and muscle formation

E. Olson, R. Bassel-Duby, J. Shelton, 2013, Nature.

Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver.

J. Shelton, M. Magnuson, S. Burgess, 2016, The Journal of clinical investigation.

Activation of Autophagic Flux Blunts Cardiac Ischemia/Reperfusion Injury

Herman I. May, Nan Jiang, Xiang Luo, 2021, Circulation research.

Loss of muscle-specific RING-finger 3 predisposes the heart to cardiac rupture after myocardial infarction

E. Olson, E. van Rooij, R. Bassel-Duby, 2007, Proceedings of the National Academy of Sciences.

Recording of pig neuronal activity in the comparative context of the awake human brain

Ana G. Hernandez-Reynoso, L. Good, S. Cogan, 2022, Scientific Reports.

Receptor Gender-Specific Pathway of Cardioprotection Mediated by the Estrogen Myocyte Enhancer Factor 2 and Class II Histone Deacetylases Control a

E. Olson, E. Rooij, J. Shelton, 2009 .

Hypercalcemia of malignancy with simultaneous elevation in serum parathyroid hormone--related peptide and 1,25-dihydroxyvitamin D in a patient with metastatic renal cell carcinoma.

J. Richardson, J. Shelton, N. Maalouf, 2009, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

Vaginal estrogen: a dual-edged sword in postoperative healing of the vaginal wall

J. Shelton, Yucel Akgul, R. Word, 2017, Menopause.

Chien-Cheng Chen, J. Shelton, C. Mendelson, 2014, Molecular endocrinology.

Cardiac failure in transgenic mice with myocardial expression of tumor necrosis factor-alpha.

R. Peshock, J. Shelton, B. Giroir, 1998, Circulation.

Cytochrome c Deficiency Causes Embryonic Lethality and Attenuates Stress-Induced Apoptosis

Xiaodong Wang, Zhijian J. Chen, J. Richardson, 2000, Cell.

Reeler/Disabled-like Disruption of Neuronal Migration in Knockout Mice Lacking the VLDL Receptor and ApoE Receptor 2

John Shelton, Joachim Herz, R. Hammer, 1999, Cell.

Global chromatin landscapes identify candidate noncoding modifiers of cardiac rhythm

G. Hon, R. Kittler, Guanghua Xiao, 2022, The Journal of clinical investigation.

Histone Deacetylase 4 Controls Chondrocyte Hypertrophy during Skeletogenesis

John M. Shelton, Eric Meadows, Rick B. Vega, 2004, Cell.

Transcription of the non-coding RNA upperhand controls Hand2 expression and heart development

John M. Shelton, E. Olson, J. McAnally, 2016, Nature.

Stem cells and their derivatives can bypass the requirement of myocardin for smooth muscle gene expression.

E. Creemers, E. Olson, J. Richardson, 2005, Developmental biology.

Critical roles of the guanylyl cyclase B receptor in endochondral ossification and development of female reproductive organs.

R. Hammer, N. Tamura, J. Richardson, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Klotho and phosphate are modulators of pathologic uremic cardiac remodeling.

Han Jun Cho, M. Wolf, Masaya Takahashi, 2015, Journal of the American Society of Nephrology : JASN.

Hippo pathway effector Yap promotes cardiac regeneration

E. Olson, J. McAnally, R. Bassel-Duby, 2013, Proceedings of the National Academy of Sciences.

Protein Kinase D1 Stimulates MEF2 Activity in Skeletal Muscle and Enhances Muscle Performance

Mi-Sung Kim, E. Olson, J. McAnally, 2008, Molecular and Cellular Biology.

Linking Spermatid Ribonucleic Acid (RNA) Binding Protein and Retrogene Diversity to Reproductive Success*

J. Richardson, J. Shelton, T. Richardson, 2013, Molecular & Cellular Proteomics.

Functional Characterization of Mouse RDH11 as a Retinol Dehydrogenase Involved in Dark Adaptation in Vivo*

A. Edwards, A. Murphy, G. Yancopoulos, 2005, Journal of Biological Chemistry.

Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1−/− mice

Kan Ding, Arti Gaur, A. Gaur, 2003, Nature Genetics.

Laryngeal aging and acoustic changes in male rat ultrasonic vocalizations.

B. Cooper, J. Shelton, C. Watts, 2013, Developmental psychobiology.

Interactions of the Low Density Lipoprotein Receptor Gene Family with Cytosolic Adaptor and Scaffold Proteins Suggest Diverse Biological Functions in Cellular Communication and Signal Transduction*

J. Richardson, J. Shelton, J. Herz, 2000, The Journal of Biological Chemistry.

Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3.

Mi-Sung Kim, E. Olson, R. Bassel-Duby, 2007, The Journal of clinical investigation.

Autophagy is an adaptive response in desmin-related cardiomyopathy

I. Benjamin, Janet L. Johnstone, J. Shelton, 2007, Proceedings of the National Academy of Sciences.

Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing

Malte Tiburcy, Wolfram-Hubertus Zimmermann, E. Olson, 2018, Science Advances.

Fusogenic micropeptide Myomixer is essential for satellite cell fusion and muscle regeneration

E. Olson, J. McAnally, R. Bassel-Duby, 2018, Proceedings of the National Academy of Sciences.

Hand2 controls osteoblast differentiation in the branchial arch by inhibiting DNA binding of Runx2

M. McKee, J. Richardson, J. Shelton, 2009, Development.

MEF2C transcription factor controls chondrocyte hypertrophy and bone development.

John McAnally, Xiaoxia Qi, E. Olson, 2007, Developmental cell.

Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle.

Jiandie D. Lin, Ferhaan Ahmad, B. Spiegelman, 2005, Cell metabolism.

Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers.

E. Olson, R. Bassel-Duby, J. Richardson, 2007, The Journal of clinical investigation.

MEF2 responds to multiple calcium‐regulated signals in the control of skeletal muscle fiber type

E. Olson, R. Bassel-Duby, T. McKinsey, 2000, The EMBO journal.

Publication : CRISPR-Cpf1 correction of muscular dystrophy mutations in human cardiomyocytes and mice

E. Olson, J. McAnally, R. Bassel-Duby, 2018 .

Derepression of sonic hedgehog signaling upon Gpr161 deletion unravels forebrain and ventricular abnormalities.

G. Konopka, J. Shelton, Saikat Mukhopadhyay, 2019, Developmental biology.

A myocardin-adjacent lncRNA balances SRF-dependent gene transcription in the heart

E. Olson, J. McAnally, R. Bassel-Duby, 2021, Genes & development.

Disruption of PPT2 in mice causes an unusual lysosomal storage disorder with neurovisceral features

J. Richardson, J. Shelton, K. Wisniewski, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Mutant screen reveals depression-associated Piccolo’s control over brain-gonad cross talk and reproductive behavior

C. Garner, E. Plautz, Xian-Jin Xie, 2019 .

Mutant screen for reproduction unveils depression-associated Piccolo’s control over reproductive behavior

C. Garner, E. Plautz, Xian-Jin Xie, 2018 .

Mutant Screen Reveals the Piccolo’s Control over Depression and Brain-Gonad Crosstalk

C. Garner, E. Plautz, Xian-Jin Xie, 2018, bioRxiv.

Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver.

J. Shelton, M. Magnuson, S. Burgess, 2015, The Journal of clinical investigation.

Mice Deficient in the Respiratory Chain Gene Cox6a2 Are Protected against High-Fat Diet-Induced Obesity and Insulin Resistance

P. Carmeliet, L. Scorrano, M. Granvik, 2013, PloS one.

Mutation of mouse Samd4 causes leanness, myopathy, uncoupled mitochondrial respiration, and dysregulated mTORC1 signaling

B. Beutler, J. Shelton, E. Moresco, 2014, Proceedings of the National Academy of Sciences.

Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice.

Nan Jiang, Xiang Luo, J. Shelton, 2012, The Journal of clinical investigation.

Regulation of hyaluronan expression during cervical ripening.

Vincent C Hascall, J. Richardson, V. Hascall, 2004, Glycobiology.

Mechanistic basis of neonatal heart regeneration revealed by transcriptome and histone modification profiling

E. Olson, R. Bassel-Duby, J. Shelton, 2019, Proceedings of the National Academy of Sciences.

Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis.

Z. Xuan, X. Wang, Michael D. Taylor, 2018, Cell reports.

Mice lacking calsarcin-1 are sensitized to calcineurin signaling and show accelerated cardiomyopathy in response to pathological biomechanical stress

E. Olson, R. Bassel-Duby, J. Richardson, 2004, Nature Medicine.

Control of Facial Muscle Development by MyoR and Capsulin

E. Olson, R. Bassel-Duby, J. Richardson, 2002, Science.

Activation of MEF2 by muscle activity is mediated through a calcineurin‐dependent pathway

J. DiMaio, E. Olson, R. Bassel-Duby, 2001, The EMBO journal.

Stimulation of Slow Skeletal Muscle Fiber Gene Expression by Calcineurin in Vivo *

E. Olson, J. Richardson, J. Shelton, 2000, The Journal of Biological Chemistry.

The Down Syndrome Critical Region Protein RCAN1 Regulates Long-Term Potentiation and Memory via Inhibition of Phosphatase Signaling

E. Klann, J. Richardson, J. Shelton, 2007, The Journal of Neuroscience.

The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization

E. Olson, J. McAnally, R. Bassel-Duby, 2021, Nature Communications.

The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization

E. Olson, J. McAnally, R. Bassel-Duby, 2021, Nature communications.

Corrigendum: Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart

Diana C. Canseco, J. Richardson, Zhigang Lu, 2015, Nature.

In vivo non-invasive monitoring of dystrophin correction in a new Duchenne muscular dystrophy reporter mouse

E. Olson, J. McAnally, R. Bassel-Duby, 2019, Nature Communications.

Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy

John M. Shelton, Hui Li, E. Olson, 2018, Science.

Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy

Hui Li, Samadrita Bhattacharyya, Florian Schmidt, 2017, Science Translational Medicine.

TRIM7 inhibits enterovirus replication and promotes emergence of a viral variant with increased pathogenicity

Milo M. Lin, M. Lin, J. Shelton, 2021, Cell.

Diminished Cardiac Fibrosis in Heart Failure is Associated with Altered Ventricular Arrhythmia Phenotype

R. Bassel-Duby, Janet L. Johnstone, Xiang Luo, 2010, Journal of cardiovascular electrophysiology.

Calcineurin Is Necessary for the Maintenance but Not Embryonic Development of Slow Muscle Fibers

E. Olson, E. van Rooij, M. Czubryt, 2005, Molecular and Cellular Biology.

Development of Slow Muscle Fibers Maintenance but Not Embryonic Calcineurin Is Necessary for the

Rhonda, E. Olson, E. Rooij, 2005 .

Alterations in Slow‐Twitch Muscle Phenotype in Transgenic Mice Overexpressing the Ca2+ Buffering Protein Parvalbumin

R. Grange, R. Bassel-Duby, J. Shelton, 2003, The Journal of physiology.

NOD2 Suppresses Colorectal Tumorigenesis via Downregulation of the TLR Pathways.

J. Shelton, J. Malter, L. Hooper, 2017, Cell reports.

LY6E protects mice from pathogenic effects of murine coronavirus and SARS-CoV-2

J. Shelton, J. Schoggins, Wenchun Fan, 2023, bioRxiv.

Cardiac autophagy is a maladaptive response to hemodynamic stress.

J. Richardson, Janet L. Johnstone, J. Shelton, 2007, The Journal of clinical investigation.

TRPC3 channels confer cellular memory of recent neuromuscular activity.

R. Bassel-Duby, J. Shelton, R. S. Williams, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Cytoglobin modulates myogenic progenitor cell viability and muscle regeneration

Diana C. Canseco, J. Richardson, Sarvjeet Singh, 2013, Proceedings of the National Academy of Sciences.

Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling.

J. Shelton, Saikat Mukhopadhyay, H. Badgandi, 2020, Developmental cell.

production by proximal tubules during ischemic AKI α Reactive oxygen species and IRF1 stimulate IFN

Keng-mean Lin, J. Richardson, J. Shelton, 2016 .

Reactive oxygen species and IRF1 stimulate IFNα production by proximal tubules during ischemic AKI.

Keng-mean Lin, J. Richardson, J. Shelton, 2013, American journal of physiology. Renal physiology.

Reactive oxygen species ( ROS ) and IRF 1 stimulate IFN α production by 1 proximal tubules during ischemic AKI . 2

Keng-mean Lin, J. Richardson, J. Shelton, 2013 .

Pathophysiology of Acute Kidney Injury Reactive oxygen species and IRF 1 stimulate IFN production by proximal tubules during ischemic

Keng-mean Lin, J. Richardson, J. Shelton, 2013 .

Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2.

Thomas M. Harris, K. Campbell, E. Olson, 2005, Genes & development.

The G protein-coupled receptor Gpr161 regulates forelimb formation, limb patterning and skeletal morphogenesis in a primary cilium-dependent manner

J. Richardson, J. Shelton, Saikat Mukhopadhyay, 2018, Development.

Requirement of MEF2A, C, and D for skeletal muscle regeneration

E. Olson, R. Bassel-Duby, J. Richardson, 2014, Proceedings of the National Academy of Sciences.

Fli1 Acts Downstream of Etv2 to Govern Cell Survival and Vascular Homeostasis via Positive Autoregulation

J. Shelton, D. Watson, N. Jiang, 2014, Circulation research.

Neuroglobin, A Novel Member of the Globin Family, Is Expressed in Focal Regions of the Brain

J. Richardson, J. Shelton, P. Mammen, 2002, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Functional correction of dystrophin actin binding domain mutations by genome editing.

Malte Tiburcy, Wolfram-Hubertus Zimmermann, E. Olson, 2017, JCI insight.

Correction of Three Prominent Mutations in Mouse and Human Models of Duchenne Muscular Dystrophy by Single-Cut Genome Editing.

E. Olson, J. McAnally, R. Bassel-Duby, 2020, Molecular therapy : the journal of the American Society of Gene Therapy.

Reactive Oxygen Species Impair Sympathetic Vasoregulation in Skeletal Muscle in Angiotensin II–Dependent Hypertension

J. Shelton, Jianfeng Ye, Xilong Li, 2006, Hypertension.

A role for the apoptosis inhibitory factor AIM/Spalpha/Api6 in atherosclerosis development.

A. Bookout, D. Mangelsdorf, P. Edwards, 2005, Cell metabolism.

Enhanced CRISPR-Cas9 correction of Duchenne muscular dystrophy in mice by a self-complementary AAV delivery system

E. Olson, R. Bassel-Duby, J. Shelton, 2020, Science Advances.

CRISPR-Cas9 corrects Duchenne muscular dystrophy exon 44 deletion mutations in mice and human cells

E. Olson, J. McAnally, R. Bassel-Duby, 2019, Science Advances.

microRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice.

E. Olson, R. Bassel-Duby, J. Richardson, 2012, The Journal of clinical investigation.

IRF-1 promotes inflammation early after ischemic acute kidney injury.

J. Richardson, J. Shelton, Xin J. Zhou, 2009, Journal of the American Society of Nephrology : JASN.

Cytoglobin Is a Stress-responsive Hemoprotein Expressed in the Developing and Adult Brain

J. Richardson, J. Shelton, P. Mammen, 2006, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Tumor physiological changes during hypofractionated stereotactic body radiation therapy assessed using multi-parametric magnetic resonance imaging

R. Mason, J. Shelton, D. Saha, 2017, Oncotarget.

Amino acid substitution in NPC1 that abolishes cholesterol binding reproduces phenotype of complete NPC1 deficiency in mice

Joseph L Goldstein, J. Richardson, J. Shelton, 2011, Proceedings of the National Academy of Sciences.

Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression.

R. Bronson, E. Olson, P. Igarashi, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Development of a Chronic Canine Ovariohysterectomy Model to Evaluate Vaginal Cuff Healing Using Two Closure Systems

J. Richardson, M. Diamond, J. Shelton, 2021, Surgical innovation.

Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides

John M. Shelton, E. Olson, R. Bassel-Duby, 2016, Science Signaling.

High Phosphate Diet Induces Exercise Intolerance and Impairs Fatty Acid Metabolism in Mice

C. Ayers, G. Iwamoto, V. Malladi, 2019, Circulation.

Adaptive Mechanisms That Preserve Cardiac Function in Mice Without Myoglobin

J. DiMaio, J. Shelton, R. S. Williams, 2001, Circulation research.

A Twist2-Dependent Progenitor Cell Contributes to Adult Skeletal Muscle

E. Olson, Beibei Chen, R. Bassel-Duby, 2017, Nature Cell Biology.

Metabolic and cardiovascular effects of chronic mild hyperuricemia in rodents

Masaya Takahashi, J. Shelton, Shanrong Zhang, 2018, Journal of Investigative Medicine.

Intracellular Protein Aggregation Is a Proximal Trigger of Cardiomyocyte Autophagy

Janet L. Johnstone, J. Shelton, B. Rothermel, 2008, Circulation.

Essential Role of STAT3 in Body Weight and Glucose Homeostasis

J. Richardson, G. Karsenty, J. Shelton, 2004, Molecular and Cellular Biology.

Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver.

J. Shelton, M. Magnuson, S. Burgess, 2016, The Journal of clinical investigation.

Temporospatial expression of the small HSP/αB‐crystallin in cardiac and skeletal muscle during mouse development

I. Benjamin, J. Richardson, J. Shelton, 1997, Developmental dynamics : an official publication of the American Association of Anatomists.

Tumor loss-of-function mutations in STK11/LKB1 induce cachexia

J. Minna, L. Girard, R. Hannan, 2023, JCI insight.

Sustained Hemodynamic Stress Disrupts Normal Circadian Rhythms in Calcineurin-Dependent Signaling and Protein Phosphorylation in the Heart

J. Bibb, M. Oh, J. Shelton, 2011, Circulation research.

Mice lacking microRNA 133a develop dynamin 2–dependent centronuclear myopathy.

E. Olson, R. Grange, R. Bassel-Duby, 2011, The Journal of clinical investigation.

LY6E is a pan-coronavirus restriction factor in the respiratory tract

J. Shelton, J. Schoggins, Jennifer L. Eitson, 2023, Nature Microbiology.

A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type.

W. Zhu, E. Olson, R. Bassel-Duby, 1998, Genes & development.

Posttraumatic Chondrocyte Apoptosis in the Murine Xiphoid

J. Borrelli, J. Shelton, C. Davis, 2013, Cartilage.

Cardiac Failure in Transgenic Mice With Myocardial Expression of Tumor Necrosis Factor-α

R. Peshock, J. Shelton, B. Giroir, 1998 .

Ectopic PLAG1 induces muscular dystrophy in the mouse.

D. Rakheja, S. Iannaccone, J. Shelton, 2023, Biochemical and biophysical research communications.

Prevention of muscular dystrophy in mice by CRISPR/Cas9–mediated editing of germline DNA

E. Olson, R. Bassel-Duby, J. Shelton, 2014, Science.

Severe myopathy in mice lacking the MEF2/SRF-dependent gene leiomodin-3.

E. Olson, R. Bassel-Duby, J. Richardson, 2015, The Journal of clinical investigation.

A reevaluation of CD22 expression in human lung cancer.

Laurentiu M. Pop, Iliodora V. Pop, J. Minna, 2014, Cancer research.

Rationale: Cardiovascular Health Depends on Proper Development and Integrity of Blood Vessels. Ets Variant 2 (etv2), Methods and Results: Using Loss-and Gain-of-function Strategies and a Series of Molecular Techniques, We Identify Friend Leukemia Integration 1 (fli1), Another E26 Transforming–specif

J. Shelton, D. Watson, N. Jiang, 2022 .

Maintenance of pig brain function under extracorporeal pulsatile circulatory control (EPCC)

L. Good, M. Peltz, J. Shelton, 2023, bioRxiv.