M. Massanella

发表

Differential gene expression in HIV-infected individuals following ART.

Douglas D. Richman, Marta Massanella, D. Richman, 2013, Antiviral research.

Single-Cell Characterization of Viral Translation-Competent Reservoirs in HIV-Infected Individuals.

B. Walker, D. Kaufmann, J. Routy, 2016, Cell host & microbe.

Intensification of a raltegravir-based regimen with maraviroc in early HIV-1 infection

B. Clotet, J. Martinez-Picado, J. Miro, 2014, AIDS.

Infrequent HIV Infection of Circulating Monocytes during Antiretroviral Therapy

J. Ananworanich, J. Routy, V. Valcour, 2019, Journal of Virology.

On the steps of cell-to-cell HIV transmission between CD4 T cells

B. Clotet, M. Massanella, J. Blanco, 2009, Retrovirology.

HIV transfer between CD4 T cells does not require LFA-1 binding to ICAM-1 and is governed by the interaction of HIV envelope glycoprotein with CD4

M. Juan, B. Clotet, J. Martinez-Picado, 2008, Retrovirology.

Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque.

P. D. de Bakker, J. Fellay, A. Telenti, 2011, The Journal of clinical investigation.

Increased ex vivo cell death of central memory CD4 T cells in treated HIV infected individuals with unsatisfactory immune recovery

B. Clotet, E. Negredo, M. Massanella, 2015, Journal of Translational Medicine.

Viremic HIV Infected Individuals with High CD4 T Cells and Functional Envelope Proteins Show Anti-gp41 Antibodies with Unique Specificity and Function

B. Clotet, P. Debré, M. Massanella, 2012, PloS one.

Brief Report: Impaired CD4 T-Cell Response to Autophagy in Treated HIV-1–Infected Individuals

B. Clotet, V. Robert-Hebmann, M. Biard-Piechaczyk, 2017, Journal of acquired immune deficiency syndromes.

Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size

Daniel I. S. Rosenbloom, Michele D. Sobolewski, R. Ptak, 2019, PLoS computational biology.

Subclinical Cytomegalovirus DNA Is Associated with CD4 T Cell Activation and Impaired CD8 T Cell CD107a Expression in People Living with HIV despite Early Antiretroviral Therapy

C. Spina, S. Gianella, M. Massanella, 2019, Journal of Virology.

Methamphetamine Use in HIV-infected Individuals Affects T-cell Function and Viral Outcome during Suppressive Antiretroviral Therapy

R. Haubrich, D. Richman, S. Little, 2015, Scientific Reports.

HIV exposed seronegative individuals show antibodies specifically recognizing native HIV envelope glycoprotein

B. Clotet, J. Benito, V. Soriano, 2013, AIDS.

Highly functional Cellular Immunity in SARS-CoV-2 Non-Seroconvertors is associated with immune protection

R. Paredes, B. Clotet, J. Prado, 2021, bioRxiv.

Neurocognitive Profile of the Post-COVID Condition in Adults in Catalonia—A Mixed Method Prospective Cohort and Nested Case–Control Study: Study Protocol

J. Prado, M. Mataró, C. Violán, 2022, Vaccines.

Skewed Cellular Distribution and Low Activation of Functional T-Cell Responses in SARS-CoV-2 Non-Seroconvertors

R. Paredes, B. Clotet, J. Prado, 2022, Frontiers in Immunology.

Assessing main death pathways in T lymphocytes from HIV infected individuals

B. Clotet, J. Martinez-Picado, E. Negredo, 2013, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Different Plasma Markers of Inflammation Are Influenced by Immune Recovery and cART Composition or Intensification in Treated HIV Infected Individuals

D. Richman, B. Clotet, J. Martinez-Picado, 2014, PloS one.

Reduced humoral response 3 months following BNT162b2 vaccination in SARS-CoV-2 uninfected residents of long-term care facilities

B. Clotet, S. Marfil, M. Massanella, 2022, Age and ageing.

Raltegravir intensification shows differing effects on CD8 and CD4 T cells in HIV-infected HAART-suppressed individuals with poor CD4 T-cell recovery

B. Clotet, J. Martinez-Picado, E. Negredo, 2012, AIDS.

Glucocorticoids’ treatment impairs the medium-term immunogenic response to SARS-CoV-2 mRNA vaccines in Systemic Lupus Erythematosus patients

B. Clotet, S. Marfil, M. Massanella, 2022, Scientific Reports.

Inappropriate sinus tachycardia in post-COVID-19 syndrome

B. Clotet, A. Bayés‐Genís, M. Massanella, 2022, Scientific reports.

Adenosine Deaminase Enhances the Immunogenicity of Human Dendritic Cells from Healthy and HIV-Infected Individuals

Felipe García, T. Gallart, J. Gatell, 2012, PloS one.

IRF7 expression correlates with HIV latency reversal upon specific blockade of immune activation

B. Clotet, J. Martinez-Picado, M. Massanella, 2022, Frontiers in Immunology.

LILAC pilot study: Effects of metformin on mTOR activation and HIV reservoir persistence during antiretroviral therapy

J. Routy, J. Goulet, M. Massanella, 2021, EBioMedicine.

Nadir CD4 T cell count as predictor and high CD4 T cell intrinsic apoptosis as final mechanism of poor CD4 T cell recovery in virologically suppressed HIV-infected patients: clinical implications.

F. Villarroya, B. Clotet, E. Negredo, 2010, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Influence of the ARV regimen on the early changes in plasma HIV RNA and immune activation at initiation of antiretroviral therapy in naïve HIV-1-infected patients.

B. Clotet, A. Samri, C. Katlama, 2020, Journal of acquired immune deficiency syndromes.

Elevated humoral response to cytomegalovirus in HIV-infected individuals with poor CD4+ T-cell immune recovery

B. Clotet, E. Negredo, M. Massanella, 2017, PloS one.

Antigp41 antibodies fail to block early events of virological synapses but inhibit HIV spread between T cells

B. Clotet, M. Bofill, M. Massanella, 2009, AIDS.

Screening NK-, B- and T-cell phenotype and function in patients suffering from Chronic Fatigue Syndrome

B. Clotet, E. Negredo, M. Massanella, 2013, Journal of Translational Medicine.

Immunodiscordant responses to HAART – mechanisms and consequences

B. Clotet, E. Negredo, M. Massanella, 2013, Expert review of clinical immunology.

Changes in T-cell subsets in HIV–HCV-coinfected patients during pegylated interferon-α2a plus ribavirin treatment

B. Clotet, C. Tural, B. Autran, 2010, Antiviral therapy.

Immunodiscordant responses to HAART - mechanisms and

B. Clotet, M. Massanella, 2013 .

Analyses of Mitochondrial DNA and Immune Phenotyping Suggest Accelerated T-Cell Turnover in Treated HIV

M. Massanella, J. Pérez-Santiago, S. Mehta, 2018, Journal of acquired immune deficiency syndromes.

Brief Report: Effect of CMV and HIV Transcription on CD57 and PD-1 T-Cell Expression During Suppressive ART

C. Spina, E. Daar, S. Gianella, 2016, Journal of acquired immune deficiency syndromes.

Dynamics of CD8 T-Cell Activation After Discontinuation of HIV Treatment Intensification

B. Clotet, J. Martinez-Picado, J. Gatell, 2013, Journal of acquired immune deficiency syndromes.

Treatment Intensification with Raltegravir in Subjects with Sustained HIV-1 Viraemia Suppression: A Randomized 48-Week Study

B. Clotet, J. Martinez-Picado, J. Gatell, 2012, Antiviral therapy.

A cell-to-cell HIV transfer assay identifies humoral responses with broad neutralization activity.

B. Clotet, Felipe García, J. Gatell, 2011, Vaccine.

Improving HIV Outgrowth by Optimizing Cell-Culture Conditions and Supplementing With all-trans Retinoic Acid

J. Routy, J. Goulet, M. Massanella, 2020, Frontiers in Microbiology.

Replication competence of virions induced from CD4+ lymphocytes latently infected with HIV

D. Richman, Xiaoying Sun, Sonia Jain, 2019, Retrovirology.

Early but limited effects of raltegravir intensification on CD4 T cell reconstitution in HIV-infected patients with an immunodiscordant response to antiretroviral therapy.

B. Clotet, J. Martinez-Picado, E. Negredo, 2013, The Journal of antimicrobial chemotherapy.

Previous SARS-CoV-2 Infection Increases B.1.1.7 Cross-Neutralization by Vaccinated Individuals

R. Paredes, B. Clotet, J. Segalés, 2021, bioRxiv.

Antiretroviral therapy suppressed participants with low CD4+ T-cell counts segregate according to opposite immunological phenotypes

R. Paredes, B. Clotet, E. Negredo, 2016, AIDS.

Continuous prophylactic ARV/ART since birth reduces seeding and persistence of the viral reservoir in vertically HIV-infected children.

J. Ananworanich, M. Robb, L. Trautmann, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Clinical course impacts early kinetics,magnitude, and amplitude of SARS-CoV-2 neutralizing antibodies beyond 1 year after infection

R. Paredes, B. Clotet, J. Segalés, 2022, Cell Reports Medicine.

Clinical course impacts early kinetics,magnitude, and amplitude of SARS-CoV-2 neutralizing antibodies beyond 1 year after infection

R. Paredes, B. Clotet, J. Segalés, 2021, Cell Reports Medicine.

Stable neutralizing antibody levels 6 months after mild and severe COVID-19 episodes

R. Paredes, B. Clotet, J. Segalés, 2021, Med.

SARS-CoV-2 infection elicits a rapid neutralizing antibody response that correlates with disease severity

R. Paredes, B. Clotet, J. Segalés, 2021, Scientific Reports.

Stable neutralizing antibody levels 6 months after mild and severe COVID-19 episodes

R. Paredes, B. Clotet, J. Segalés, 2020, bioRxiv.

Standard vaccines increase HIV-1 transcription during antiretroviral therapy

Felipe García, M. Plana, S. Gianella, 2016, AIDS.

Cytomegalovirus Replication in Semen Is Associated with Higher Levels of Proviral HIV DNA and CD4+ T Cell Activation during Antiretroviral Treatment

R. Haubrich, D. Richman, S. Little, 2014, Journal of Virology.

Gut Lactobacillales are associated with higher CD4 and less microbial translocation during HIV infection

D. Richman, S. Little, C. Spina, 2013, AIDS.

Biomarker candidates for progression and clinical management of COVID-19 associated pneumonia at time of admission

B. Clotet, M. Massanella, J. Blanco, 2022, Scientific reports.

Susceptibility of Human Lymphoid Tissue Cultured ex vivo to Xenotropic Murine Leukemia Virus-Related Virus (XMRV) Infection

B. Clotet, M. Bofill, M. Massanella, 2012, PloS one.

HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects

Sarah Palmer, Roger Paredes, Viktor Dahl, 2010, Nature Medicine.

Cell-free mitochondrial DNA in CSF is associated with early viral rebound, inflammation, and severity of neurocognitive deficits in HIV infection

R. Ellis, S. Gianella, S. Letendre, 2016, Journal of NeuroVirology.

Attacking the HIV Reservoir from the Immune and Viral Perspective

J. Martinez-Picado, M. Massanella, J. Blanco, 2013, Current HIV/AIDS Reports.

Deep Molecular Characterization of HIV-1 Dynamics under Suppressive HAART

R. Paredes, B. Clotet, J. Martinez-Picado, 2011, PLoS pathogens.

Long-term effects of early antiretroviral initiation on HIV reservoir markers: a longitudinal analysis of the MERLIN clinical study

M. Massanella, N. Chomont, J. Lama, 2021, The Lancet. Microbe.

Critical Presentation of a Severe Acute Respiratory Syndrome Coronavirus 2 Reinfection: A Case Report

R. Paredes, B. Clotet, J. Segalés, 2021, Open forum infectious diseases.

Continuous Prophylactic Antiretrovirals/Antiretroviral Therapy Since Birth Reduces Seeding and Persistence of the Viral Reservoir in Children Vertically Infected With Human Immunodeficiency Virus

J. Ananworanich, M. Robb, S. Sirivichayakul, 2020, Clinical Infectious Diseases.

Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection

D. Kaufmann, J. Routy, M. Massanella, 2019, PLoS pathogens.

CD4 T-cell hyperactivation and susceptibility to cell death determine poor CD4 T-cell recovery during suppressive HAART

B. Clotet, E. Negredo, M. Bofill, 2010, AIDS.

The Sordid Affair Between Human Herpesvirus and HIV.

S. Gianella, Davey M. Smith, M. Massanella, 2015, The Journal of infectious diseases.

Evaluation of the Aptima HIV-1 Quant Dx Assay for HIV-1 RNA Quantitation in Different Biological Specimen Types

D. Richman, R. Ellis, S. Gianella, 2017, Journal of Clinical Microbiology.

Residual inflammation and viral reservoirs: alliance against an HIV cure

M. Massanella, R. Fromentin, N. Chomont, 2016, Current opinion in HIV and AIDS.

Phenotypic characterization of single CD4+ T cells harboring genetically intact and inducible HIV genomes

J. Routy, B. Murrell, M. Massanella, 2023, Nature Communications.

Improved assays to measure and characterize the inducible HIV reservoir

D. Richman, M. Massanella, S. Lada, 2018, EBioMedicine.

OP 3.3 – 00030 Inducible replication-competent HIV proviruses persist in memory CD4+ T cells expressing high levels of the integrin VLA-4 (α4β1)

J. Routy, M. Massanella, B. Routy, 2022, Journal of virus eradication.

Quantification of Total and 2-LTR (Long terminal repeat) HIV DNA, HIV RNA and Herpesvirus DNA in PBMCs.

D. Richman, S. Gianella, M. Strain, 2015, Bio-protocol.

Replication of Human Herpesviruses Is Associated with Higher HIV DNA Levels during Antiretroviral Therapy Started at Early Phases of HIV Infection

D. Richman, S. Little, S. Gianella, 2016, Journal of Virology.

Measuring the latent reservoir in vivo.

D. Richman, M. Massanella, 2016, The Journal of clinical investigation.

Quantification of HIV RNA and Human Herpesvirus DNA in Seminal Plasma.

S. Gianella, C. Ignacio, M. Massanella, 2015, Bio-protocol.

The effect of cell subset isolation method on gene expression in leukocytes

C. Spina, M. Massanella, N. Beliakova-Bethell, 2014, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size

Michael P. Busch, Jun Lai, John W. Mellors, 2018, bioRxiv.

TL1A–DR3 Plasma Levels Are Predictive of HIV-1 Disease Control, and DR3 Costimulation Boosts HIV-1–Specific T Cell Responses

B. Clotet, À. Olvera, J. Martinez-Picado, 2020, The Journal of Immunology.

Correlation between Clinical and Immunological Variables and Humoral Response to SARS-CoV-2 Vaccination in Adult Patients with Antibody Deficiency Disorders

B. Clotet, M. Massanella, J. Carrillo, 2022, Pathogens.

Limited humoral and specific T-cell responses after SARS-CoV-2 vaccination in PLWH with poor immune reconstitution

R. Paredes, B. Clotet, J. Prado, 2022, The Journal of infectious diseases.

Kinetics of immune responses elicited after three mRNA COVID-19 vaccine doses in predominantly antibody-deficient individuals

B. Clotet, J. Segalés, J. Prado, 2022, iScience.

Impact of hybrid immunity booster vaccination and Omicron breakthrough infection on SARS-CoV-2 VOCs cross-neutralization

B. Clotet, S. Marfil, M. Massanella, 2023, iScience.

Impact of chemotherapy and/or immunotherapy on neutralizing antibody response to SARS‐CoV‐2 mRNA‐1237 vaccine in patients with solid tumors

B. Clotet, S. Marfil, M. Massanella, 2022, Molecular oncology.

SARS-CoV-2 Infection Modulates ACE2 Function and Subsequent Inflammatory Responses in Swabs and Plasma of COVID-19 Patients

B. Clotet, J. Pascual, M. Massanella, 2021, Viruses.

SARS-CoV-2 infection suppresses ACE2 function and antiviral immune response in the upper respiratory tract of infected patients

B. Clotet, J. Pascual, M. Massanella, 2020, bioRxiv.

Pharmacological Inhibition of IKK to Tackle Latency and Hyperinflammation in Chronic HIV-1 Infection

B. Clotet, G. Sirera, M. Massanella, 2022, International journal of molecular sciences.

Lack of concordance between residual viremia and viral variants driving de novo infection of CD4+ T cells on ART

R. Paredes, B. Clotet, J. Martinez-Picado, 2016, Retrovirology.

Memory B cell dysregulation in HIV-1-infected individuals

B. Clotet, E. Negredo, M. Massanella, 2017, AIDS.

Preserved immune functionality and high CMV-specific T-cell responses in HIV-infected individuals with poor CD4+ T-cell immune recovery

B. Clotet, E. Negredo, M. Massanella, 2017, Scientific Reports.

Multiparametric characterization of rare HIV-infected cells using an RNA-flow FISH technique

D. Kaufmann, J. Routy, Nirmin Alsahafi, 2017, Nature Protocols.

Comparison of Reverse Transcription (RT)-Quantitative PCR and RT-Droplet Digital PCR for Detection of Genomic and Subgenomic SARS-CoV-2 RNA

J. Martinez-Picado, M. Massanella, J. Carrillo, 2023, Microbiology spectrum.

semen is associated with higher levels of proviral HIV DNA and CD 4 + T cell activation during antiretroviral treatment

R. Haubrich, D. Richman, S. Little, 2014 .

Efficacy of SARS-CoV-2 vaccination in patients with monoclonal gammopathies: A cross sectional study

B. Clotet, S. Marfil, M. Massanella, 2022, Life Science Alliance.

Cross-sectional study to assess the efficacy of SARS-CoV-2 vaccination in patients with monoclonal gammopathies

B. Clotet, S. Marfil, M. Massanella, 2022, medRxiv.

Ef ﬁ cacy of SARS-CoV-2 vaccination in patients with monoclonal gammopathies: A cross sectional study

B. Clotet, M. Massanella, J. Blanco, 2022 .

SARS-CoV-2 infection elicits a rapid neutralizing antibody response that correlates with disease severity

B. Clotet, J. Segalés, L. Ruiz, 2021, Scientific Reports.

The reconstitution of the thymus in immunosuppressed individuals restores CD4‐specific cellular and humoral immune responses

B. Clotet, L. Ruiz, J. Romeu, 2011, Immunology.

Limited immune responses after three months of BNT162b2 vaccine in SARS-CoV-2 uninfected elders living in long-term care facilities

B. Clotet, S. Marfil, M. Massanella, 2021, medRxiv.

Inducible HIV RNA transcription assays to measure HIV persistence: pros and cons of a compromise

M. Massanella, N. Chomont, Johann Plantin, 2018, Retrovirology.

Demonstration of antibodies against SARS-CoV-2, neutralizing or binding, in seroconversion panels after mRNA-1273, BNT-162b2 and Ad26.COV2.S vaccine administration.

S. Marfil, M. Massanella, J. Blanco, 2022, medRxiv.

Correlation between Clinical and Immunological Variables and Humoral Response to SARS-CoV-2 Vaccination in Adult Patients with Antibody Deficiency Disorders

B. Clotet, M. Massanella, J. Carrillo, 2022, Pathogens.

Preserved immune functionality and high CMV-specific T-cell responses in HIV-infected individuals with poor CD4+ T-cell immune recovery

B. Clotet, E. Negredo, M. Massanella, 2017, Scientific Reports.

Inducible HIV RNA transcription assays to measure HIV persistence: pros and cons of a compromise

M. Massanella, N. Chomont, Johann Plantin, 2018, Retrovirology.

HIV transfer between CD4 T cells does not require LFA-1 binding to ICAM-1 and is governed by the interaction of HIV envelope glycoprotein with CD4

M. Juan, B. Clotet, J. Martinez-Picado, 2008, Retrovirology.

Differential gene expression in HIV-infected individuals following ART.

D. Richman, S. Little, M. Massanella, 2013, Antiviral research.

Treatment Intensification with Raltegravir in Subjects with Sustained HIV-1 Viraemia Suppression: A Randomized 48-Week Study

B. Clotet, J. Martinez-Picado, J. Gatell, 2012, Antiviral therapy.

Continuous Prophylactic Antiretrovirals/Antiretroviral Therapy Since Birth Reduces Seeding and Persistence of the Viral Reservoir in Children Vertically Infected With Human Immunodeficiency Virus

J. Ananworanich, L. Trautmann, T. Puthanakit, 2021 .

Cell-free mitochondrial DNA in CSF is associated with early viral rebound, inflammation, and severity of neurocognitive deficits in HIV infection

R. Ellis, S. Gianella, S. Letendre, 2015, Journal of NeuroVirology.

Determinants of the onset and prognosis of the post-COVID-19 condition: a 2-year prospective observational cohort study

B. Clotet, M. Massanella, M. Nevot, 2023, The Lancet Regional Health - Europe.

HIV transfer between CD4 T cells does not require LFA-1 binding to ICAM-1 and is governed by the interaction of HIV envelope glycoprotein with CD4

M. Juan, B. Clotet, J. Martinez-Picado, 2008, Retrovirology.