D. Leeman

发表

FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis.

F. Guillemot, A. Brunet, Marius Wernig, 2013, Cell reports.

Efficacy of TG101348, a selective JAK2 inhibitor, in treatment of a murine model of JAK2V617F-induced polycythemia vera.

Sandra A. Moore, Y. Ko, R. Levine, 2008, Cancer cell.

Dynamic landscape and regulation of RNA editing in mammals

D. Conrad, Jin Billy Li, A. Brunet, 2017, Nature.

Single-Cell Transcriptomic Analysis Defines Heterogeneity and Transcriptional Dynamics in the Adult Neural Stem Cell Lineage.

A. Brunet, S. Boutet, D. Leeman, 2017, Cell reports.

-secretase inhibitors γ Notch1 mutations and are sensitive to induced T-cell lymphoblastic lymphoma/leukemias harbor - K-RasG12D

S. Fröhling, C. Scholl, D. Leeman, 2013 .

K-RasG12D-induced T-cell lymphoblastic lymphoma/leukemias harbor Notch1 mutations and are sensitive to gamma-secretase inhibitors.

S. Fröhling, C. Scholl, D. Gilliland, 2008, Blood.

Kinase activation and transformation by NUP214-ABL1 is dependent on the context of the nuclear pore.

P. Marynen, M. Fornerod, D. Gilliland, 2008, Molecular cell.

Stem cells: Sex specificity in the blood

A. Brunet, D. Leeman, Dena S. Leeman, 2014, Nature.

Age-associated cryptic transcription in mammalian stem cells is linked to permissive chromatin at cryptic promoters

Yun Huang, Luyang Sun, A. Webb, 2020 .

K-Ras G12D –induced T-cell lymphoblastic lymphoma/leukemias harbor Notch1 mutations and are sensitive to (cid:1) -secretase inhibitors

S. Fröhling, C. Scholl, D. Gilliland, 2008 .

Single cell analysis reveals T cell infiltration in old neurogenic niches

Mark M. Davis, I. Weissman, A. Brunet, 2019, Nature.

Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging

E. Passegué, A. Brunet, J. Frydman, 2018, Science.

FOXO3 regulates a common genomic program in aging and glioblastoma stem cells

N. Neretti, A. Brodsky, Abigail K. Brown, 2021, Aging and cancer.

Members of the H 3 K 4 trimethylation complex regulate lifespan in a germline-dependent manner in C . elegans

E. Greer, A. Brunet, O. Gozani, 2010 .

EXEL-8232, a small-molecule JAK2 inhibitor, effectively treats thrombocytosis and extramedullary hematopoiesis in a murine model of myeloproliferative neoplasm induced by MPLW515L

D. Gilliland, M. Kharas, D. Leeman, 2012, Leukemia.

Altered chromatin states drive cryptic transcription in aging mammalian stem cells

Luyang Sun, A. Webb, D. Leeman, 2021, Nature Aging.

FOXO 3 Shares Common Targets with ASCL 1 Genome-wide and Inhibits ASCL 1-Dependent Neurogenesis

F. Guillemot, A. Brunet, Marius Wernig, 2013 .

In vitro and in vivo CRISPR-Cas9 screens reveal drivers of aging in neural stem cells of the brain

A. Brunet, Robin W. Yeo, D. Morgens, 2021, bioRxiv.

Members of the Histone H3 Lysine 4 Trimethylation Complex Regulate Lifespan in a Germline-dependent Manner in C. elegans

Or Gozani, E. Greer, A. Brunet, 2010, Nature.