G. Iguchi

发表

Branched-chain amino acids reduce hindlimb suspension-induced muscle atrophy and protein levels of atrogin-1 and MuRF1 in rats.

K. Chihara, Taiki Maki, Daisuke Yamamoto, 2012, Nutrition research.

Adult growth hormone deficiency in Japan: results of investigation by questionnaire.

K. Chihara, K. Iida, G. Iguchi, 2002, Endocrine journal.

Branched‐chain amino acids protect against dexamethasone‐induced soleus muscle atrophy in rats

Y. Sugiyama, K. Chihara, Taiki Maki, 2010, Muscle & nerve.

Mechanistic insights into immune checkpoint inhibitor-related hypophysitis: a form of paraneoplastic syndrome

G. Iguchi, Yutaka Takahashi, W. Ogawa, 2021, Cancer Immunology, Immunotherapy.

Cross-sectional prevalence of pancreatic cystic lesions in patients with acromegaly, a single-center experience

S. Yamada, Kenichi Yoshida, G. Iguchi, 2017, Pituitary.

Chemerin regulates β-cell function in mice

T. Abe, H. Kiyonari, R. Kitazawa, 2011, Scientific reports.

IGF-I stimulates reactive oxygen species (ROS) production and inhibits insulin-dependent glucose uptake via ROS in 3T3-L1 adipocytes.

K. Chihara, K. Iida, G. Iguchi, 2010, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Gene expression profile in the heart of spontaneous dwarf rat: in vivo effects of growth hormone.

K. Chihara, K. Iida, G. Iguchi, 2006, Biochemical and biophysical research communications.

A PROP1-binding factor, AES cloned by yeast two-hybrid assay represses PROP1-induced Pit-1 gene expression

Y. Sugiyama, K. Chihara, Daisuke Yamamoto, 2013, Molecular and Cellular Endocrinology.

Insulin secretion and sensitivity before and after surgical treatment for aldosterone-producing adenoma.

G. Iguchi, Yutaka Takahashi, W. Ogawa, 2020, Diabetes & metabolism.

Smoking and small, dense low-density lipoprotein particles: cross-sectional study.

M. Shimizu, G. Iguchi, Shunzo Kobayashi, 2008, Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco.

Pathogenesis of Anti–PIT-1 Antibody Syndrome: PIT-1 Presentation by HLA Class I on Anterior Pituitary Cells

Kenichi Yoshida, G. Iguchi, Yutaka Takahashi, 2019, Journal of the Endocrine Society.

Kenichi Yoshida, G. Iguchi, Yutaka Takahashi, 2018, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Two Cases of Atezolizumab-Induced Hypophysitis

Kenichi Yoshida, G. Iguchi, Yutaka Takahashi, 2017, Journal of the Endocrine Society.

D-dimer as a significant marker of deep vein thrombosis in patients with subclinical or overt Cushing's syndrome.

G. Iguchi, Yutaka Takahashi, H. Nishizawa, 2014, Endocrine journal.

IGF-I induces senescence of hepatic stellate cells and limits fibrosis in a p53-dependent manner

Kenichi Yoshida, G. Iguchi, Yutaka Takahashi, 2016, Scientific Reports.

IGF-I enhances cellular senescence via the reactive oxygen species-p53 pathway.

G. Iguchi, Yutaka Takahashi, H. Nishizawa, 2012, Biochemical and biophysical research communications.

Decreased serum chemerin levels in male Japanese patients with type 2 diabetes: sex dimorphism.

M. Kasuga, G. Iguchi, Yutaka Takahashi, 2013, Endocrine journal.

Long-term effects of growth hormone replacement therapy on liver function in adult patients with growth hormone deficiency.

G. Iguchi, Yutaka Takahashi, H. Nishizawa, 2014, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Prevalence of Simple Renal Cysts in Acromegaly.

G. Iguchi, Yutaka Takahashi, H. Nishizawa, 2016, Internal medicine.

Insulin Secretion and Insulin Sensitivity Before and After Surgical Treatment of Pheochromocytoma or Paraganglioma

G. Iguchi, Yutaka Takahashi, W. Ogawa, 2017, The Journal of clinical endocrinology and metabolism.

Nonalcoholic fatty liver disease in adult hypopituitary patients with GH deficiency and the impact of GH replacement therapy.

R. Kitazawa, S. Kitazawa, K. Chihara, 2012, European journal of endocrinology.

Hepatic failure and enhanced oxidative stress in mitochondrial diabetes.

R. Kitazawa, S. Kitazawa, Hiroyuki Yamada, 2008, Endocrine journal.

Reactive oxygen species play an essential role in IGF-I signaling and IGF-I-induced myocyte hypertrophy in C2C12 myocytes.

S. Seino, K. Chihara, G. Iguchi, 2011, Endocrinology.

Intravenous administration of ghrelin stimulates growth hormone secretion in vagotomized patients as well as normal subjects.

K. Chihara, G. Iguchi, Yutaka Takahashi, 2004, European journal of endocrinology.

The influence of type 2 diabetes on serum GH and IGF-I levels in hospitalized Japanese patients.

Kenichi Yoshida, G. Iguchi, Yutaka Takahashi, 2016, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

GH-independent IGF-I action is essential to prevent the development of nonalcoholic steatohepatitis in a GH-deficient rat model.

R. Kitazawa, G. Iguchi, Yutaka Takahashi, 2012, Biochemical and biophysical research communications.

Hormonal regulation of the human ghrelin receptor gene transcription.

Y. Yoshimoto, K. Iida, G. Iguchi, 2001, Biochemical and biophysical research communications.

Genetic and clinical characteristics of Japanese patients with sporadic somatotropinoma.

S. Yamada, Kenichi Yoshida, G. Iguchi, 2016, Endocrine journal.

Cloning and characterization of the 5(')-flanking region of the human ghrelin gene.

K. Chihara, G. Iguchi, Yutaka Takahashi, 2003, Biochemical and biophysical research communications.

Median-lower normal levels of serum thyroxine are associated with low triiodothyronine levels and body temperature in patients with central hypothyroidism.

G. Iguchi, Yutaka Takahashi, W. Ogawa, 2015, European journal of endocrinology.

Enhanced oxidative stress in GH-transgenic rat and acromegaly in humans.

S. Seino, F. Hakuno, Shin-ichiro Takahashi, 2012, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Isolated adrenocorticotropic hormone deficiency as a form of paraneoplastic syndrome

Kenichi Yoshida, G. Iguchi, Yutaka Takahashi, 2018, Pituitary.

Accelerated Telomere Shortening in Acromegaly; IGF-I Induces Telomere Shortening and Cellular Senescence

S. Yamada, Kenichi Yoshida, G. Iguchi, 2015, PloS one.

Two Cases of anti–PIT-1 Hypophysitis Exhibited as a Form of Paraneoplastic Syndrome not Associated With Thymoma

G. Iguchi, Yutaka Takahashi, W. Ogawa, 2020, Journal of the Endocrine Society.

Autoimmune pituitary disease: New concepts with clinical implications.

G. Iguchi, Yutaka Takahashi, Masaaki Yamamoto, 2020, Endocrine reviews.

The role of circulating ghrelin in growth hormone (GH) secretion in freely moving male rats.

K. Chihara, K. Iida, G. Iguchi, 2003, Life sciences.

SIRT1 regulates adaptive response of the growth hormone--insulin-like growth factor-I axis under fasting conditions in liver

S. Seino, G. Iguchi, Yutaka Takahashi, 2013, Proceedings of the National Academy of Sciences.

Multiple Salivary Cortisol Measurements Are a Useful Tool to Optimize Metyrapone Treatment in Patients with Cushing’s Syndromes Treatment: Case Presentations

Kenichi Yoshida, G. Iguchi, Yutaka Takahashi, 2018, Front. Endocrinol..

Advantages of Intraprocedural Unenhanced CT During Adrenal Venous Sampling to Confirm Accurate Catheterization of the Right Adrenal Vein

T. Murakami, G. Iguchi, M. Yamaguchi, 2018, CardioVascular and Interventional Radiology.

Low Serum IGF-I/GH Ratio Is Associated with Abnormal Glucose Tolerance in Acromegaly

K. Chihara, K. Iida, G. Iguchi, 2008, Hormone Research in Paediatrics.

Cloning of a protein binding to the most proximal Pit-1 binding element of prolactin gene from human pituitary cDNA library

K. Chihara, G. Iguchi, Yutaka Takahashi, 2003, Molecular and Cellular Endocrinology.

Kenichi Yoshida, G. Iguchi, Yutaka Takahashi, 2019, Pituitary.

The prevalence of IgG4-related hypophysitis in 170 consecutive patients with hypopituitarism and/or central diabetes insipidus and review of the literature.

G. Iguchi, Yutaka Takahashi, H. Nishizawa, 2014, European journal of endocrinology.

Responsiveness to DDAVP in Cushing’s disease is associated with USP8 mutations through enhancing AVPR1B promoter activity

S. Yamada, G. Iguchi, Yutaka Takahashi, 2022, Pituitary.

Patients with pheochromocytoma exhibit low aldosterone renin ratio-preliminary reports

Kenichi Yoshida, G. Iguchi, Yutaka Takahashi, 2020, BMC Endocrine Disorders.

A missense single-nucleotide polymorphism in the sialic acid acetylesterase (SIAE) gene is associated with anti-PIT-1 antibody syndrome.

T. Ogata, G. Iguchi, Yutaka Takahashi, 2014, Endocrine journal.

Adult combined GH, prolactin, and TSH deficiency associated with circulating PIT-1 antibody in humans.

S. Seino, K. Chihara, K. Iida, 2011, The Journal of clinical investigation.

Cloning and Characterization of the 5′-Flanking Region of the Human Growth Hormone-releasing Hormone Receptor Gene*

K. Chihara, G. Iguchi, Yutaka Takahashi, 1999, The Journal of Biological Chemistry.

Kobe University Repository : Kernel タイトル Tit le Expression of mPOU Protein in the Human Pituitary Adenomas

T. Kuno, K. Chihara, G. Iguchi, 2018 .

W194XProp1 and S156insTProp1, both of which have intact DNA-binding domain, show a different DNA-binding activity to the Prop1-binding element in human Pit-1 gene

Y. Sugiyama, K. Chihara, Taiki Maki, 2010, Molecular and Cellular Endocrinology.

Identification and analysis of prophet of Pit-1-binding sites in human Pit-1 gene.

Y. Sugiyama, K. Chihara, Daisuke Yamamoto, 2008, Endocrinology.

Expression of mPOU protein in the human pituitary adenomas.

T. Kuno, K. Chihara, G. Iguchi, 2003, The Kobe journal of medical sciences.

Cloning and characterization of the 5'-flanking region of the human prolactin-releasing peptide receptor gene.

K. Iida, G. Iguchi, H. Kaji, 2000, Biochemical and biophysical research communications.

Involvement of PIT-1-reactive cytotoxic T lymphocytes in anti-PIT-1 antibody syndrome.

G. Iguchi, Yutaka Takahashi, Y. Okimura, 2014, The Journal of clinical endocrinology and metabolism.

Differentiation of human induced pluripotent stem cells into hypothalamic vasopressin neurons with minimal exogenous signals and partial conversion to the naive state

G. Iguchi, Yutaka Takahashi, R. Banno, 2022, Scientific Reports.

Rostral Hypothalamic Differentiation With Minimal Exogenous Signals in Human Naive Induced Pluripotent Stem Cells

G. Iguchi, Yutaka Takahashi, H. Arima, 2022 .

Efficacy of combined octreotide and cabergoline treatment in patients with acromegaly: a retrospective clinical study and review of the literature.

S. Yamada, G. Iguchi, Yutaka Takahashi, 2013, Endocrine journal.

A diagnostic pitfall in IgG4-related hypophysitis: infiltration of IgG4-positive cells in the pituitary of granulomatosis with polyangiitis

Kenichi Yoshida, G. Iguchi, Yutaka Takahashi, 2015, Pituitary.

Clinical Heterogeneity of Acquired Idiopathic Isolated Adrenocorticotropic Hormone Deficiency

Kenichi Yoshida, K. Iida, G. Iguchi, 2021, Frontiers in Endocrinology.

Oncogenic ras induces gastrin/CCKB receptor gene expression in human colon cancer cell lines LoVo and Colo320HSR

K. Chihara, G. Iguchi, H. Yamada, 2003 .

Regulation of EP4 expression via the Sp-1 transcription factor: inhibition of expression by anti-cancer agents.

H. Kamitani, Takashi Watanabe, T. Eling, 2008, Biochimica et biophysica acta.

Acromegaly caused by a somatotroph adenoma in patient with neurofibromatosis type 1.

Kenichi Yoshida, K. Kosaki, G. Iguchi, 2019, Endocrine journal.

Cardiac myxoma caused by fumarate hydratase gene deletion in patient with cortisol-secreting adrenocortical adenoma.

H. Sasano, K. Chihara, M. Fujisawa, 2020, The Journal of clinical endocrinology and metabolism.

A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2.

Seong-ho Lee, S. Baek, T. Eling, 2009, Cancer letters.

Multifocal fibrosclerosis as a possible cause of panhypopituitarism with central diabetes insipidus.

G. Iguchi, H. Kaji, Y. Okimura, 2000, Endocrine journal.

A novel thymoma-associated autoimmune disease: Anti-PIT-1 antibody syndrome

Kenichi Yoshida, G. Iguchi, Yutaka Takahashi, 2017, Scientific Reports.

Bilateral adrenal uptake of 123I MIBG scintigraphy with mild catecholamine elevation, the diagnostic dilemma, and its characteristics

M. Fujisawa, A. Imagawa, T. Kanda, 2022, Scientific Reports.

Anti-PIT-1 antibody syndrome; a novel clinical entity leading to hypopituitarism.

G. Iguchi, Yutaka Takahashi, Masaaki Yamamoto, 2015, Pediatric endocrinology reviews : PER.

Combined Hypophysitis and Type 1 Diabetes Mellitus Related to Immune Checkpoint Inhibitors

G. Iguchi, Y. Hirota, Y. Okada, 2023, Journal of the Endocrine Society.

A Novel Clinical Entity of Autoimmune Endocrinopathy: Anti-PIT-1 Antibody Syndrome.

G. Iguchi, Yutaka Takahashi, H. Bando, 2017, Frontiers of hormone research.

Multifocal Fibroscierosis as a Possible Cause of Panhypo-pituitarism with Central Diabetes Insipidus

G. Iguchi, Yutaka Takahashi, Y. Okimura, 2006 .

Survey of glucocorticoid dose escalation in patients with adrenal insufficiency during the peri-COVID-19 vaccination period.

G. Iguchi, Masaaki Yamamoto, Shin Urai, 2022, Endocrine journal.

The quality of life in acromegalic patients with biochemical remission by surgery alone is superior to that in those with pharmaceutical therapy without radiotherapy, using the newly developed Japanese version of the AcroQoL

Kenichi Yoshida, G. Iguchi, Yutaka Takahashi, 2015, Pituitary.

The Effect of Aging on Quality of Life in Acromegaly Patients Under Treatment

G. Iguchi, Yutaka Takahashi, Masaaki Yamamoto, 2022, Frontiers in Endocrinology.

The prevalence of acromegaly in hospitalized patients with type 2 diabetes.

G. Iguchi, Yutaka Takahashi, H. Nishizawa, 2015, Endocrine journal.

Novel Function of the Transactivation Domain of a Pituitary-specific Transcription Factor, Pit-1*

K. Yagita, H. Okamura, K. Chihara, 2002, The Journal of Biological Chemistry.

Congenital pituitary hypoplasia model demonstrates hypothalamic OTX2 regulation of pituitary progenitor cells.

G. Iguchi, Yutaka Takahashi, W. Ogawa, 2019, The Journal of clinical investigation.

Oncogenic ras induces gastrin/CCKB receptor gene expression in human colon cancer cell lines LoVo and Colo320HSR.

K. Chihara, G. Iguchi, H. Yamada, 2003, The Journal of laboratory and clinical medicine.

The prevalence and associated factors of colorectal neoplasms in acromegaly: a single center based study

G. Iguchi, Yutaka Takahashi, H. Nishizawa, 2015, Pituitary.

Novel genes and variants associated with congenital pituitary hormone deficiency in the era of next-generation sequencing

S. Camper, G. Iguchi, Masaaki Yamamoto, 2022, Frontiers in Endocrinology.

A case of Luscan-Lumish syndrome: Possible involvement of enhanced GH signaling.

H. Nagai, K. Chihara, G. Iguchi, 2020, The Journal of clinical endocrinology and metabolism.

Relation between the insulin lowering rate and changes in bone mineral density: Analysis among subtypes of type 1 diabetes mellitus

G. Iguchi, Y. Hirota, Y. Okada, 2022, Journal of diabetes investigation.

Novel ultrasonic bone densitometry based on two longitudinal waves: significant correlation with pQCT measurement values and age-related changes in trabecular bone density, cortical thickness, and elastic modulus of trabecular bone in a normal Japanese population

T. Otani, T. Fujita, G. Iguchi, 2010, Osteoporosis International.

Cloning and Characterization of the 5′-Flanking Region of the Human Growth Hormone Secretagogue Receptor Gene*

K. Chihara, G. Iguchi, Yutaka Takahashi, 1998, The Journal of Biological Chemistry.

SAT-LB079 Clinical Heterogeneity of Acquired Idiopathic ACTH Deficiency: A New Classification Based on the Clinical Characteristics and Autoantibodies

K. Iida, G. Iguchi, Yutaka Takahashi, 2019, Journal of the Endocrine Society.

Case report: Late middle-aged features of FAM111A variant, Kenny–Caffey syndrome type 2-suggestive symptoms during a long follow-up

G. Iguchi, Masaaki Yamamoto, Shin Urai, 2023, Frontiers in Endocrinology.

[A Novel Clinical Entity "Anti-PIT-1 Antibody Syndrome"--Autoimmunity against a Transcription Factor].

G. Iguchi, Yutaka Takahashi, H. Bando, 2015, Rinsho byori. The Japanese journal of clinical pathology.

The impact of adrenal tumor multidisciplinary team meetings on clinical outcomes

M. Fujisawa, T. Kanda, G. Iguchi, 2020, Endocrine.