J. Levijoki

发表

Sirtuin1-p53, forkhead box O3a, p38 and post-infarct cardiac remodeling in the spontaneously diabetic Goto-Kakizaki rat

E. Vahtola, M. Louhelainen, Hanna Forstén, 2010, Cardiovascular diabetology.

Troponin C-mediated calcium sensitization by levosimendan accelerates the proportional development of isometric tension.

J. Levijoki, H. Haikala, I. Lindén, 1995, Journal of molecular and cellular cardiology.

Cardiac troponin C as a target protein for a novel calcium sensitizing drug, levosimendan.

J. Levijoki, H. Haikala, I. Lindén, 1995, Journal of molecular and cellular cardiology.

Caloric Restriction Ameliorates Angiotensin II–Induced Mitochondrial Remodeling and Cardiac Hypertrophy

M. Lalowski, M. Orešič, M. Baumann, 2012, Hypertension.

Inotropic effect of NCX inhibition depends on the relative activity of the reverse NCX assessed by a novel inhibitor ORM‐10962 on canine ventricular myocytes

J. Papp, J. Levijoki, N. Nagy, 2018, European journal of pharmacology.

The effects of levosimendan and OR-1896 on isolated hearts, myocyte-sized preparations and phosphodiesterase enzymes of the guinea pig.

I. Édes, P. Kaheinen, J. Levijoki, 2004, European journal of pharmacology.

Improved survival with simendan after experimental myocardial infarction in rats.

P. Kaheinen, J. Levijoki, P. Pollesello, 2001, European journal of pharmacology.

Effects of the calcium sensitizer OR‐1896, a metabolite of levosimendan, on post‐infarct heart failure and cardiac remodelling in diabetic Goto–Kakizaki rats

E. Vahtola, M. Louhelainen, S. Merasto, 2010, British journal of pharmacology.

Discovery and characterization of ORM‐11372, a novel inhibitor of the sodium‐calcium exchanger with positive inotropic activity

Paul E. Miller, J. Papp, J. Levijoki, 2020, British Journal of Pharmacology.

Discovery and characterization of ORM-11372, a unique and positively inotropic sodium-calcium exchanger/inhibitor.

Paul E. Miller, J. Papp, J. Levijoki, 2020, British journal of pharmacology.

Novel Na+/Ca2+ Exchanger Inhibitor ORM-10962 Supports Coupled Function of Funny-Current and Na+/Ca2+ Exchanger in Pacemaking of Rabbit Sinus Node Tissue

J. Papp, A. Loewe, J. Levijoki, 2020, Frontiers in Pharmacology.

Levosimendan Increases Diastolic Coronary Flow in Isolated Guinea-Pig Heart by Opening ATP-Sensitive Potassium Channels

P. Kaheinen, J. Levijoki, P. Pollesello, 2001, Journal of cardiovascular pharmacology.

Effects of levosimendan in experimental acute coxsackievirus myocarditis

V. Kytö, J. Levijoki, A. Saraste, 2009, European journal of clinical investigation.

Troponin C–Mediated Calcium Sensitization Induced by Levosimendan Does Not Impair Relaxation

J. Levijoki, H. Haikala, I. Lindén, 1995, Journal of cardiovascular pharmacology.

Caloric restriction ameliorates kidney ischaemia/reperfusion injury through PGC‐1α–eNOS pathway and enhanced autophagy

J. Levijoki, E. Mervaala, P. Finckenberg, 2013, Acta physiologica.

Effects of Levosimendan and Milrinone on Oxygen Consumption in Isolated Guinea-Pig Heart

P. Kaheinen, J. Levijoki, P. Pollesello, 2004, Journal of cardiovascular pharmacology.

The Adenylate Cyclase Activator Forskolin Potentiates the Positive Inotropic Effect of the Phosphodiesterase Inhibitor Milrinone But Not of the Calcium Sensitizer Levosimendan nor of Its Hemodynamically Active Metabolites: An Apparent Conundrum

J. Levijoki, Z. Papp, E. Grossini, 2022, Journal of cardiovascular pharmacology.

AMPK activator AICAR ameliorates ischaemia reperfusion injury in the rat kidney

J. Levijoki, E. Mervaala, P. Finckenberg, 2012, British journal of pharmacology.

Effects of calcium sensitizer OR-1986 on a cardiovascular mortality and myocardial remodelling in hypertensive Dahl/Rapp rats.

E. Vahtola, M. Louhelainen, S. Merasto, 2009, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

Efficacy of selective NCX inhibition by ORM-10103 during simulated ischemia/reperfusion.

J. Papp, J. Levijoki, N. Nagy, 2014, European journal of pharmacology.

Levosimendan alone and in combination with valsartan prevents stroke in Dahl salt-sensitive rats.

J. Levijoki, J. Yrjänheikki, O. Gröhn, 2015, European journal of pharmacology.

Oral levosimendan prevents postinfarct heart failure and cardiac remodeling in diabetic Goto-Kakizaki rats

E. Vahtola, M. Louhelainen, Hanna Forstén, 2009, Journal of hypertension.

Effects of levosimendan on cardiac gene expression profile and post-infarct cardiac remodelling in diabetic Goto-Kakizaki rats.

E. Vahtola, M. Louhelainen, S. Merasto, 2011, Basic & clinical pharmacology & toxicology.

Levosimendan improves cardiac function and survival in rats with angiotensin II-induced hypertensive heart failure

F. Luft, M. Louhelainen, S. Merasto, 2010, Hypertension Research.

Cardiovascular effects of the combination of levosimendan and valsartan in hypertensive Dahl/Rapp rats.

J. Levijoki, E. Mervaala, P. Finckenberg, 2011, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

Comparison of the efficiency of Na+/Ca2+ exchanger or Na+/H+ exchanger inhibition and their combination in reducing coronary reperfusion-induced arrhythmias.

J. Levijoki, A. Varró, P. Pollesello, 2015, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

The reverse mode of the Na+/Ca2+ exchanger contributes to the pacemaker mechanism in rabbit sinus node cells

J. Papp, A. Loewe, J. Levijoki, 2022, Scientific reports.

Extracellular membrane vesicles from umbilical cord blood-derived MSC protect against ischemic acute kidney injury, a feature that is lost after inflammatory conditioning

J. Tuimala, P. Siljander, J. Levijoki, 2013, Journal of extracellular vesicles.

Dexmedetomidine preconditioning ameliorates kidney ischemia-reperfusion injury

J. Levijoki, E. Mervaala, P. Finckenberg, 2014, Pharmacology research & perspectives.

Intramyocardial BNP Gene Delivery Improves Cardiac Function Through Distinct Context-Dependent Mechanisms

J. Rysä, R. Serpi, O. Vuolteenaho, 2011, Circulation. Heart failure.

ORM‐10103, a novel specific inhibitor of the Na+/Ca2+ exchanger, decreases early and delayed afterdepolarizations in the canine heart

J. Levijoki, N. Nagy, L. Virág, 2013, British journal of pharmacology.

Two Inotropes With Different Mechanisms of Action: Contractile, PDE-Inhibitory and Direct Myofibrillar Effects of Levosimendan and Enoximone

Szabolcs Szilágyi, István Bak, J. Levijoki, 2005, Journal of cardiovascular pharmacology.

Exacerbation of acute kidney injury by bone marrow stromal cells from rats with persistent renin-angiotensin system activation.

J. Levijoki, E. Mervaala, D. Müller, 2015, Clinical science.

The role of cAMP- and cGMP-dependent protein kinases in the cardiac actions of the new calcium sensitizer, levosimendan.

P. Kaheinen, J. Levijoki, H. Haikala, 1997, Cardiovascular research.

Further evidence for the cardiac troponin C mediated calcium sensitization by levosimendan: structure-response and binding analysis with analogs of levosimendan.

A. Annila, I. Kilpeläinen, J. Levijoki, 2000, Journal of molecular and cellular cardiology.

Orally Available Levosimendan Dose-Related Positive Inotropic and Lusitropic Effect in Conscious Chronically Instrumented Normal and Heart Failure Dogs

J. Levijoki, S. Masutani, W. Little, 2008, Journal of Pharmacology and Experimental Therapeutics.

The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments

J. Papp, J. Levijoki, N. Nagy, 2016, PloS one.

EFFECTS OF CALCIUM SENSITIZER OR-1986 ON CARDIOVASCULAR MORTALITY AND MYOCARDIAL REMODELLING IN HYPERTENSIVE

E. Vahtola, S. Merasto, P. Kaheinen, 2009 .

Effects of levosimendan on cardiac remodeling and cardiomyocyte apoptosis in hypertensive Dahl/Rapp rats

E. Vahtola, M. Louhelainen, S. Merasto, 2007, British journal of pharmacology.

Long‐term effects of Na+/Ca2+ exchanger inhibition with ORM‐11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction

B. Pieske, M. Falcke, J. Levijoki, 2019, European journal of heart failure.

Effect of levosimendan therapy on myocardial infarct size and left ventricular function after acute coronary occlusion

J. Knuuti, M. Teräs, J. Levijoki, 2016, Heart.

ORM-3819 promotes cardiac contractility through Ca(2+) sensitization in combination with selective PDE III inhibition, a novel approach to inotropy.

J. Papp, J. Levijoki, Z. Papp, 2016, European journal of pharmacology.

Complex electrophysiological remodeling in postinfarction ischemic heart failure

Zhong Jian, Zana Coulibaly, Ye Chen-Izu, 2018, Proceedings of the National Academy of Sciences.

Discovery and Structural Characterization of a Phospholamban‐Binding Cyclic Peptide and Design of Novel Inhibitors of Phospholamban

A. Annila, J. Levijoki, M. Yliperttula, 2013, Chemical biology & drug design.

Blockade of sodium‑calcium exchanger via ORM-10962 attenuates cardiac alternans

J. Papp, J. Tomek, B. Rodríguez, 2020, Journal of molecular and cellular cardiology.

Selective Na+/Ca2+ exchanger inhibition prevents Ca2+ overload‐induced triggered arrhythmias

J. Papp, J. Levijoki, N. Nagy, 2014, British journal of pharmacology.

Rapid Absorption of Naloxone from Eye Drops

H. Joensuu, J. Levijoki, Sari Pappinen, 2022, Pharmaceuticals.

ORM‐10103, a novel specific inhibitor of the Na+/Ca2+ exchanger, decreases early and delayed afterdepolarizations in the canine heart

J. Papp, J. Levijoki, N. Nagy, 2013, British journal of pharmacology.

An experimental study of consecutive administration of ropinirole and apomorphine for emesis induction in dogs.

J. Levijoki, Lasse I Saloranta, Arja M Vuorela, 2023, Journal of veterinary emergency and critical care.

Ocular Administration of Palonosetron in the Prevention of Cisplatin-Induced Nausea and Vomiting

H. Joensuu, J. Levijoki, Sari Pappinen, 2023, The Journal of Pharmacology and Experimental Therapeutics.

Efficacy of selective NCX inhibition by ORM-10103 during simulated ischemia/reperfusion.

J. Papp, J. Levijoki, N. Nagy, 2014, European journal of pharmacology.