S. Ward

R. Mrsny, S. Ward, E. Carter, 2013, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Millipede-like lymphocyte crawling: feeling the way with filopodia.

S. Ward, 2009, Immunity.

A p38 MAP kinase inhibitor SB203580 inhibits CD28-dependent T cell proliferation and IL-2 production.

R. Parry, S. Ward, L. O’Neill, 1997, Biochemical Society transactions.

PI3K isoforms as drug targets in inflammatory diseases: lessons from pharmacological and genetic strategies.

S. Ward, Stephanie J. Harris, J. G. Foster, 2009, Current opinion in investigational drugs.

Leukocyte navigation mechanisms as targets in airway diseases.

S. Ward, M. Watson, D. A. Medina-Tato, 2006, Drug discovery today.

Sat-Nav for T cells: Role of PI3K isoforms and lipid phosphatases in migration of T lymphocytes.

J. Westwick, S. Ward, Stephanie J. Harris, 2011, Immunology letters.

Differential modulation of COX-2 expression in A549 airway epithelial cells by structurally distinct PPAR(gamma) agonists: evidence for disparate functional effects which are independent of NF-(kappa)B and PPAR(gamma).

P. Chakravarty, P. Whittaker, S. Ward, 2005, Cellular Signalling.

New drug targets in inflammation: efforts to expand the anti‐inflammatory armoury

S. Ward, 2008, British journal of pharmacology.

The fusion of quantitative molecular proteomics and immune‐oncology: a step towards precision medicine in cancer therapeutics

S. Ward, B. Larijani, J. Miles, 2022, FEBS letters.

Inhibition activity of sulfated polysaccharide of Sepiella maindroni ink on matrix metalloproteinase (MMP)-2.

Guanjun Chen, S. Ward, Xian-Jun Qu, 2008, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Calcium release activity and metabolism of inositol 1,4,5-trisphosphate in T cells. Modulation by novel inositol 1,4,5-trisphosphate 5-phosphatase inhibitors.

J. Westwick, S. Ward, B. Potter, 1994, European journal of biochemistry.

Toward the development of potent and selective bisubstrate inhibitors of protein arginine methyltransferases.

Wei Hong, R. Parry, S. Ward, 2010, Bioorganic & medicinal chemistry letters.

Isoform-specific phosphoinositide 3-kinase inhibitors as therapeutic agents.

P. Finan, S. Ward, 2003, Current opinion in pharmacology (Print).

Modulation of P-glycoprotein activity by the substituted quinoxalinone compound QA3 in adriamycin-resistant K562/A02 cells

S. Ward, Xian-Jun Qu, Xiao-Fan Zhang, 2010, Pharmacological reports : PR.

Reversal effect of substituted 1,3-dimethyl-1H-quinoxalin-2-ones on multidrug resistance in adriamycin-resistant K562/A02 cells.

Ming-Hui Chen, Wei Tang, S. Ward, 2009, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

The Chemokines CXCL9, CXCL10, and CXCL11 Differentially Stimulate Gαi-Independent Signaling and Actin Responses in Human Intestinal Myofibroblasts1

George Kolios, S. Ward, R. Nibbs, 2005, The Journal of Immunology.

Nitric oxide in inflammatory bowel disease: a universal messenger in an unsolved puzzle

S. Ward, G. Kolios, V. Valatas, 2004, Immunology.

Do phosphoinositide 3-kinases direct lymphocyte navigation?

S. Ward, 2004, Trends in immunology.

Chemokines: understanding their role in T-lymphocyte biology.

J. Westwick, S. Ward, S G Ward, 1998, The Biochemical journal.

Editorial: Stromal and immune cell interactions in intestinal inflammation and fibrosis

S. Ward, G. Kolios, K. Kitamura, 2023, Frontiers in Immunology.

Activation of Phosphatidylinositol 3-Kinase by Interleukin-13

J. Westwick, S. Ward, G. Kolios, 1997, The Journal of Biological Chemistry.

Inhibition of PI3K Signaling Spurs New Therapeutic Opportunities in Inflammatory/Autoimmune Diseases and Hematological Malignancies

S. Ward, E. Carter, M. Blunt, 2012, Pharmacological Reviews.

Chemokine Signaling in T-Lymphocyte Migration: The Role of Phosphoinositide 3-kinase

Laura G. E. Smith, S. Ward, A. Webb, 2007 .

T lymphocytes on the move: chemokines, PI 3-kinase and beyond.

S. Ward, 2006, Trends in immunology.

Therapeutic potential of phosphoinositide 3-kinase inhibitors.

P. Finan, S. Ward, J. Dowden, 2003, Chemistry & biology.

Cytokine-induced Apoptosis in Epithelial HT-29 Cells Is Independent of Nitric Oxide Formation

J. Westwick, S. Ward, G. Kolios, 1999, The Journal of Biological Chemistry.

Inhibition of CD28‐mediated T cell costimulation by the phosphoinositide 3‐kinase inhibitor wortmannin

J. Westwick, S. Ward, D. Sansom, 1995, European journal of immunology.

Hnf4α is a key gene that can generate columnar metaplasia in oesophageal epithelium

J. Slack, S. Ward, D. Tosh, 2017, Differentiation; research in biological diversity.

Phosphoinositide 3-kinases in T lymphocyte activation.

S. Ward, D. Cantrell, S G Ward, 2001, Current opinion in immunology.

Ligation of CD28 Stimulates the Formation of a Multimeric Signaling Complex Involving Grb-2-Associated Binder 2 (Gab2), Src Homology Phosphatase-2, and Phosphatidylinositol 3-Kinase: Evidence That Negative Regulation of CD28 Signaling Requires the Gab2 Pleckstrin Homology Domain1

R. Parry, S. Ward, M. Welham, 2006, The Journal of Immunology.

Signalling to suit function: tailoring phosphoinositide 3-kinase during T-cell activation.

R. Parry, S. Ward, J. Riley, 2007, Trends in immunology.

Chemokine Is a Dispensable Signal for T the CCR4 Ligand Macrophage-Derived Activation of Phosphoinositide 3-Kinases by

S. Ward, Darran G. Cronshaw, Z. Brown, 2013 .

Activation of Phosphoinositide 3-Kinases by the CCR4 Ligand Macrophage-Derived Chemokine Is a Dispensable Signal for T Lymphocyte Chemotaxis1

S. Ward, Darran G. Cronshaw, Z. Brown, 2004, The Journal of Immunology.

Lymphocyte Chemotaxis Chemokine Is a Dispensable Signal for T the CCR 4 Ligand Macrophage-Derived Activation of Phosphoinositide 3-Kinases

S. Ward, Z. Brown, C. Owen, 2004 .

Two Distinct Intracytoplasmic Regions of the T-cell Adhesion Molecule CD28 Participate in Phosphatidylinositol 3-Kinase Association (*)

D. Olive, S. Ward, R. Sweet, 1996, The Journal of Biological Chemistry.

Both CD28 ligands CD80 (B7-1) and CD86 (B7-2) activate phosphatidylinositol 3-kinase, and wortmannin reveals heterogeneity in the regulation of T cell IL-2 secretion.

G. Freeman, B. Levine, C. June, 1995, International immunology.

Autophosphorylation of p110δ phosphoinositide 3‐kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivo

M. Waterfield, B. Vanhaesebroeck, S. Ward, 1999, The EMBO journal.

PI 3-kinase: a pivotal pathway in T-cell activation?

D. Olive, C. June, S. Ward, 1996, Immunology today.

PI3Kgamma is the dominant isoform involved in migratory responses of human T lymphocytes: effects of ex vivo maintenance and limitations of non-viral delivery of siRNA.

J. Westwick, E. Hickman, R. Parry, 2007, Cellular signalling.

Fine tuning T lymphocytes: a role for the lipid phosphatase SHIP-1.

R. Parry, S. Ward, Stephanie J. Harris, 2010, Biochimica et biophysica acta.

Positioning Phosphoinositide 3-Kinase in Chemokine and Antigen-Dependent T-Lymphocyte Navigation Mechanisms

S. Ward, 2010 .

Mechanisms of chemokine and antigen-dependent T-lymphocyte navigation.

S. Ward, F. Marelli-Berg, 2009, The Biochemical journal.

Phosphoinositide Lipid Phosphatases: Natural Regulators of Phosphoinositide 3-Kinase Signaling in T Lymphocytes*

J. Westwick, R. Parry, S. Ward, 2008, Journal of Biological Chemistry.

PI3K comes of age

P. Finan, S. Ward, M. Welham, 2003, Nature Immunology.

Unique role of the PI3-Kδ isoform in immunity

S. Ward, 2002 .

Evidence for PI3K-dependent CXCR3 agonist-induced degranulation of human cord blood-derived mast cells.

J. Westwick, S. Ward, I. Mirkina, 2010, Molecular immunology.

Optimal Chemotactic Responses of Leukemic T Cells to Stromal Cell-Derived Factor-1 Requires the Activation of Both Class IA and IB Phosphoinositide 3-Kinases1

S. Ward, K. Wright, Y. Sotsios, 2003, The Journal of Immunology.

IB Phosphoinositide 3-Kinases Requires the Activation of Both Class IA and T Cells to Stromal Cell-Derived Factor-1 Optimal Chemotactic Responses of Leukemic

S. Ward, K. Wright, Y. Sotsios, 2003 .

The CC Chemokine Monocyte Chemotactic Peptide-1 Activates both the Class I p85/p110 Phosphatidylinositol 3-Kinase and the Class II PI3K-C2α*

M. Waterfield, J. Westwick, S. Ward, 1998, The Journal of Biological Chemistry.

Chemokines and T lymphocytes: more than an attraction.

J. Westwick, S. Ward, K. Bacon, 1998, Immunity.

Time resolved amplified FRET identifies protein kinase B activation state as a marker for poor prognosis in clear cell renal cell carcinoma

P. Parker, S. Ward, B. Larijani, 2017, BBA clinical.

Inhibitors of p56lck: assessing their potential as tools for manipulating T-lymphocyte activation

S. Ward, J. Dowden, 2001 .

RANTES-activated human T lymphocytes. A role for phosphoinositide 3-kinase.

J. Westwick, S. Ward, L. Turner, 1995, Journal of immunology.

Pharmacological Targeting of Phosphoinositide Lipid Kinases and Phosphatases in the Immune System: Success, Disappointment, and New Opportunities

S. Ward, M. Blunt, Matthew D. Blunt, 2012, Front. Immun..

Regulatory role of phosphatidylinositol 3-kinase on TNF-alpha-induced cyclooxygenase 2 expression in colonic epithelial cells.

S. Ward, M. Russo, C. Jobin, 2001, Gastroenterology.

Determination of Interactive States of Immune Checkpoint Regulators in Lung Metastases after Radiofrequency Ablation

I. Soubeyran, A. Italiano, S. Ward, 2022, Cancers.

Quantification of biomarker functionality predicts patient outcomes

P. Parker, S. Ward, B. Larijani, 2021, British Journal of Cancer.

CD28: a signalling perspective.

S. Ward, 1996, The Biochemical journal.

Induction of activator protein (AP)-1 and nuclear factor-kappaB by CD28 stimulation involves both phosphatidylinositol 3-kinase and acidic sphingomyelinase signals.

S. Ward, D. Sansom, C. Edmead, 1996, Journal of immunology.

Antibody ligation of CD7 leads to association with phosphoinositide 3‐kinase and phosphatidylinositol 3,4,5‐trisphosphate formation in T lymphocytes

J. Westwick, R. Parry, S. Ward, 1995, European journal of immunology.

Temporal variation in CB2R levels following T lymphocyte activation: evidence that cannabinoids modulate CXCL12-induced chemotaxis.

S. Ward, K. Coopman, K. Wright, 2007, International immunopharmacology.

Signaling Events Involved in Chemokine‐Directed T Lymphocyte Migration

S. Ward, 2011 .

Heterologous regulation of chemokine receptor signaling by the lipid phosphatase SHIP in lymphocytes.

J. Westwick, S. Ward, C. M. Wain, 2005, Cellular signalling.

Chemokine signalling: pivoting around multiple phosphoinositide 3‐kinases

S. Ward, Adam P. Curnock, Marisa K. Logan, 2002, Immunology.

Measurement of phosphoinositide 3-kinase activity.

S. Ward, 2000, Methods in molecular biology.

Differential modulation of COX-2 expression in A549 airway epithelial cells by structurally distinct PPARγ agonists : Evidence for disparate functional effects which are independent of NF-κB and PPARγ

P. Chakravarty, P. Whittaker, S. Ward, 2005 .

Phosphoinositide 3-kinases in the gut: a link between inflammation and cancer?

S. Ward, S. A. Weaver, Stephen G. Ward, 2001, Trends in molecular medicine.

How does inflammation cause Barrett's metaplasia?

S. Ward, D. Tosh, B. Colleypriest, 2009, Current opinion in pharmacology.

Mitochondrial Superoxide Generation Enhances P2X7R-Mediated Loss of Cell Surface CD62L on Naive Human CD4+ T Lymphocytes

S. Ward, E. Carter, I. Kilty, 2013, The Journal of Immunology.

TCR signal quality determines trafficking of CTLA-4 to immunological synapse

S. Ward, 2002 .

Differential regulation of prostaglandin E biosynthesis by interferon‐γ in colonic epithelial cells

S. Ward, K. Coopman, G. Kolios, 2004, British journal of pharmacology.

Measurement of Phosphoinositide 3-Kinase Activation by Interleukins

S. Ward, 2001 .

Evidence That the Lipid Phosphatase SHIP-1 Regulates T Lymphocyte Morphology and Motility

J. Westwick, R. Parry, S. Ward, 2011, The Journal of Immunology.

Toll-like receptors in the spotlight

S. Ward, L. O’Neill, Z. Brown, 2003, Nature Immunology.

Development and characterisation of tetracycline-regulated phosphoinositide 3-kinase mutants: assessing the role of multiple phosphoinositide 3-kinases in chemokine signaling.

S. Ward, A. Curnock, 2003, Journal of immunological methods.

A role for phosphoinositide 3--kinase in RANTES induced chemotaxis of T lymphocytes.

J. Westwick, S. Ward, L. Turner, 1995, Biochemical Society Transactions.

Heme oxygenase-1: a novel anti-inflammatory mediator

S. Ward, 2002 .

Targeting PI3K isoforms and SHIP in the immune system: new therapeutics for inflammation and leukemia.

S. Ward, Matthew D. Blunt, 2012, Current opinion in pharmacology.

Chemokines: understanding their role in T-lymphocyte biology.

J. Westwick, S. Ward, 1998, The Biochemical journal.

Assessing the role of multiple phosphoinositide 3-kinases in chemokine signaling: use of dominant negative mutants controlled by a tetracycline-regulated gene expression system.

S. Ward, Y. Sotsios, A. Curnock, 2004, Methods in molecular biology.