N. Ahmad

KyungMann Kim, N. Ahmad, J. Johnson, 2020, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

Anti‐proliferative and proapoptotic effects of (−)‐epigallocatechin‐3‐gallate on human melanoma: Possible implications for the chemoprevention of melanoma

H. Mukhtar, G. Wood, M. Nihal, 2005, International journal of cancer.

The sirtuin 6: An overture in skin cancer

N. Ahmad, L. M. Garcia-Peterson, Glorimar Guzmán‐Pérez, 2019, Experimental dermatology.

Over‐expression of cyclooxygenase‐2 in human prostate adenocarcinoma

D. Bostwick, H. Mukhtar, N. Ahmad, 2000, The Prostate.

Inhibition of ultraviolet B-mediated activation of nuclear factor κB in normal human epidermal keratinocytes by green tea Constituent (-)-epigallocatechin-3-gallate

V. Adhami, H. Mukhtar, N. Ahmad, 2003, Oncogene.

Inhibition of enhancer of zeste homolog 2 (EZH2) overcomes enzalutamide resistance in castration-resistant prostate cancer

Lang Li, N. Ahmad, Xiaoqi Liu, 2019, The Journal of Biological Chemistry.

Melatonin in cancer management: progress and promise.

N. Ahmad, Brittney Jung, 2006, Cancer research.

Inhibition of Plk1 represses androgen signaling pathway in castration-resistant prostate cancer

N. Ahmad, Xiaoqi Liu, Long Chen, 2015, Cell cycle.

Prevention of Ultraviolet‐B Radiation Damage by Resveratrol in Mouse Skin Is Mediated via Modulation in Survivin ¶

N. Ahmad, F. Afaq, M. Aziz, 2005 .

Health Benefits of Tea Consumption

V. Adhami, H. Mukhtar, N. Ahmad, 2004 .

The Role of Sirtuins in Antioxidant and Redox Signaling.

N. Ahmad, C. Singh, M. Ndiaye, 2017, Antioxidants & redox signaling.

The role of SIRT1 in cancer: the saga continues.

N. Ahmad, Melissa J Wilking, Melissa J. Wilking, 2015, The American journal of pathology.

Molecular signatures of sanguinarine in human pancreatic cancer cells: A large scale label-free comparative proteomics approach

M. Nihal, N. Ahmad, C. Singh, 2015, Oncotarget.

Photodynamic therapy results in induction of WAF1/CIP1/P21 leading to cell cycle arrest and apoptosis.

R. Agarwal, D. Feyes, H. Mukhtar, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Low-dose arsenic-mediated metabolic shift is associated with activation of Polo-like kinase 1 (Plk1)

N. Ahmad, Xiaoqi Liu, K. Strebhardt, 2015, Cell cycle.

Cotargeting Polo-Like Kinase 1 and the Wnt/β-Catenin Signaling Pathway in Castration-Resistant Prostate Cancer

A. Zoubeidi, J. Li, T. Ratliff, 2015, Molecular and Cellular Biology.

Plk1 Phosphorylation of PTEN Causes a Tumor-Promoting Metabolic State

J. Li, S. Kuang, P. Bi, 2014, Molecular and Cellular Biology.

Up-regulation of clusterin during phthalocyanine 4 photodynamic therapy-mediated apoptosis of tumor cells and ablation of mouse skin tumors.

H. Mukhtar, D. Boothman, N. Ahmad, 2000, Cancer research.

Dietary Phytochemicals in Zinc Homeostasis: A Strategy for Prostate Cancer Management

Hao Chang, N. Ahmad, C. Singh, 2021, Nutrients.

Polo-like kinase 1 (Plk1) in non-melanoma skin cancers

M. Nihal, W. Zhong, N. Ahmad, 2009, Cell cycle.

Antioxidants of the beverage tea in promotion of human health.

V. Adhami, H. Mukhtar, I. Siddiqui, 2004, Antioxidants & redox signaling.

Essential role of caspases in epigallocatechin-3-gallate-mediated inhibition of nuclear factor kappaB and induction of apoptosis

H. Mukhtar, N. Ahmad, F. Afaq, 2004, Oncogene.

The role of Forkhead-box Class O (FoxO) transcription factors in cancer: a target for the management of cancer.

N. Ahmad, Shannon R Reagan-Shaw, 2007, Toxicology and applied pharmacology.

Regulation of PTEN degradation and NEDD4–1 E3 ligase activity by Numb

N. Ahmad, Xiaoqi Liu, Zhiguo Li, 2017, Cell cycle.

SIRT1 deacetylase is overexpressed in human melanoma and its small molecule inhibition imparts anti-proliferative response via p53 activation.

M. Nihal, W. Zhong, N. Ahmad, 2014, Archives of biochemistry and biophysics.

Polo‐like kinase (Plk) 1: a novel target for the treatment of prostate cancer

N. Ahmad, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Modulation of phosphatidylinositol‐3‐kinase/protein kinase B‐ and mitogen‐activated protein kinase‐pathways by tea polyphenols in human prostate cancer cells

V. Adhami, H. Mukhtar, I. Siddiqui, 2004, Journal of cellular biochemistry.

Antiproliferative Effects of Apple Peel Extract Against Cancer Cells

H. Mukhtar, N. Ahmad, Shannon R Reagan-Shaw, 2010, Nutrition and cancer.

Disposable Electrochemical Immunosensor for Prostate Cancer Detection

S. Gunasekaran, N. Ahmad, M. Mutlu, 2022, Sensors and Actuators B: Chemical.

Polo-like Kinase 1 Facilitates Loss of Pten Tumor Suppressor-induced Prostate Cancer Formation

Liang Cheng, T. Ratliff, N. Ahmad, 2011, The Journal of Biological Chemistry.

Polo-like kinase 1 (Plk1) is expressed by cutaneous T-cell lymphomas (CTCLs), and its downregulation promotes cell cycle arrest and apoptosis

G. Wood, M. Nihal, N. Ahmad, 2011, Cell cycle.

Co-targeting HSP90 and its client proteins for treatment of prostate cancer

N. Ahmad, Xiaoqi Liu, Long Chen, 2016 .

Cotargeting HSP90 and Its Client Proteins for Treatment of Prostate Cancer

J. Li, J. Larner, N. Ahmad, 2016, Molecular Cancer Therapeutics.

Involvement of Nitric Oxide during Phthalocyanine (Pc4) Photodynamic Therapy-mediated Apoptosis1

H. Mukhtar, N. Ahmad, Gupta, 2006 .

[32] Mechanism of photodynamic therapy-induced cell death

H. Mukhtar, N. Ahmad, 2000 .

Involvement of retinoblastoma (Rb) and E2F transcription factors during photodynamic therapy of human epidermoid carcinoma cells A431

H. Mukhtar, N. Ahmad, Sanjay Gupta, 1999, Oncogene.

Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease?

B. Longley, N. Ahmad, M. Aziz, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Resveratrol in cancer management: where are we and where we go from here?

Raj Kumar, N. Ahmad, M. Ndiaye, 2011, Annals of the New York Academy of Sciences.

Melanoma Chemoprevention: Current Status and Future Prospects

N. Ahmad, M. Ndiaye, L. M. Garcia-Peterson, 2017, Photochemistry and photobiology.

Green tea polyphenols and cancer: biologic mechanisms and practical implications.

H. Mukhtar, N. Ahmad, 2009, Nutrition reviews.

Prostate cancer chemoprevention by green tea.

S. Gupta, H. Mukhtar, N. Ahmad, 1999, Seminars in urologic oncology.

Methaneseleninic acid and γ-Tocopherol combination inhibits prostate tumor growth in Vivo in a xenograft mouse model

H. Mukhtar, I. Siddiqui, M. Nihal, 2014, Oncotarget.

CRISPR/Cas9‐mediated Knockout of SIRT6 Imparts Remarkable Antiproliferative Response in Human Melanoma Cells in vitro and in vivo

K. Iczkowski, N. Ahmad, C. Singh, 2020, Photochemistry and photobiology.

Cancer chemoprevention by resveratrol: in vitro and in vivo studies and the underlying mechanisms (review).

Raj Kumar, N. Ahmad, M. Aziz, 2003, International journal of oncology.

Photodynamic therapy results in induction of WAF 1 y CIP 1 y P 21 leading to cell cycle arrest and apoptosis

R. Agarwal, D. Feyes, H. Mukhtar, 1998 .

DNA Damage Response-Independent Role for MDC1 in Maintaining Genomic Stability

C. Carlock, N. Ahmad, Xiaoqi Liu, 2017, Molecular and Cellular Biology.

Resveratrol, in its natural combination in whole grape, for health promotion and disease management

N. Ahmad, Xiaoqi Liu, C. Singh, 2015, Annals of the New York Academy of Sciences.

Prostate cancer chemoprevention by green tea: in vitro and in vivo inhibition of testosterone-mediated induction of ornithine decarboxylase.

R. Mohan, S. Gupta, H. Mukhtar, 1999, Cancer research.

Green tea and skin.

H. Mukhtar, S. Katiyar, N. Ahmad, 2000, Archives of dermatology.

Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols

J. Lewin, H. Mukhtar, N. Ahmad, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Suppression of ultraviolet B exposure-mediated activation of NF-kappaB in normal human keratinocytes by resveratrol.

V. Adhami, N. Ahmad, F. Afaq, 2003, Neoplasia.

Prevention of short-term ultraviolet B radiation-mediated damages by resveratrol in SKH-1 hairless mice.

V. Adhami, N. Ahmad, F. Afaq, 2003, Toxicology and applied pharmacology.

Modulations of critical cell cycle regulatory events during chemoprevention of ultraviolet B-mediated responses by resveratrol in SKH-1 hairless mouse skin

N. Ahmad, F. Afaq, M. Aziz, 2004, Oncogene.

Cytochrome P-450-dependent drug metabolism in skin.

R. Agarwal, H. Mukhtar, N. Ahmad, 1996, Clinics in dermatology.

Introducing nanochemoprevention as a novel approach for cancer control: proof of principle with green tea polyphenol epigallocatechin-3-gallate.

S. Mousa, V. Adhami, H. Mukhtar, 2009, Cancer research.

Chemoprotective effects of dietary grape powder on ultraviolet B radiation-mediated skin carcinogenesis in SKH-1 hairless mice

N. Ahmad, C. Singh, M. Ndiaye, 2019 .

Involvement of Bcl-2 and Bax in Photodynamic Therapy-mediated Apoptosis

H. Mukhtar, N. Ahmad, Sanjay Gupta, 2001, The Journal of Biological Chemistry.

Mechanism of Cancer Chemopreventive Activity of Green Tea

H. Mukhtar, N. Ahmad, 1999 .

Green tea in chemoprevention of cancer.

H. Mukhtar, N. Ahmad, 1999, Toxicological sciences : an official journal of the Society of Toxicology.

(-)-Epigallocatechin-3-gallate (EGCG) sensitizes melanoma cells to interferon induced growth inhibition in a mouse model of human melanoma

H. Ahsan, H. Mukhtar, G. Wood, 2009, Cell cycle.

A definitive role of ornithine decarboxylase in photocarcinogenesis.

H. Mukhtar, S. Katiyar, N. Ahmad, 2001, The American journal of pathology.

Prevention of collagen-induced arthritis in mice by a polyphenolic fraction from green tea.

S. Gupta, H. Mukhtar, N. Ahmad, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Melatonin, a novel Sirt1 inhibitor, imparts antiproliferative effects against prostate cancer in vitro in culture and in vivo in TRAMP model

H. Mukhtar, I. Siddiqui, B. Jung-Hynes, 2010, Journal of pineal research.

Mechanism of photodynamic therapy-induced cell death.

H. Mukhtar, N. Ahmad, 2000, Methods in enzymology.

Cutaneous Photochemoprotection by Green Tea: A Brief Review

H. Mukhtar, N. Ahmad, 2001, Skin Pharmacology and Physiology.

Mechanisms of Immunotherapy Resistance in Cutaneous Melanoma: Recognizing a Shapeshifter

N. Ahmad, C. Singh, Glorimar Guzmán‐Pérez, 2022, Frontiers in Oncology.

Editorial: Mechanisms of resistance to the targeted therapy and immunotherapy in cutaneous melanoma

N. Ahmad, S. Premi, Yong Qin, 2022, Frontiers in Oncology.

Effects and Mechanism of Nicotinamide Against UVA‐ and/or UVB‐mediated DNA Damages in Normal Melanocytes

N. Ahmad, C. Singh, Charlotte A. Mintie, 2018, Photochemistry and photobiology.

Quercetin–Resveratrol Combination for Prostate Cancer Management in TRAMP Mice

I. Siddiqui, N. Ahmad, C. Singh, 2020, Cancers.

RNA interference-mediated knockdown of SIRT1 and/or SIRT2 in melanoma: Identification of downstream targets by large-scale proteomics analysis.

N. Ahmad, Xiaoqi Liu, M. Ndiaye, 2018, Journal of proteomics.

A Homozygous Missense Variant in KRT25 Underlying Overlapping Phenotype with Woolly Hair and Dental Anomalies.

I. Rayment, N. Ahmad, J. Sgro, 2022, The Journal of investigative dermatology.

Alterations in cell cycle regulation in mouse skin tumors.

H. Mukhtar, N. Ahmad, S. Balasubramanian, 1998, Biochemical and biophysical research communications.

Involvement of Fas (APO-1/CD-95) during photodynamic-therapy-mediated apoptosis in human epidermoid carcinoma A431 cells.

S. Gupta, D. Feyes, H. Mukhtar, 2000, Journal of Investigative Dermatology.

Overexpression of ornithine decarboxylase in prostate cancer and prostatic fluid in humans.

D. Bostwick, M. Resnick, R. Mohan, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Advances in Brief Up-Regulation of Clusterin during Phthalocyanine 4 Photodynamic Therapy-mediated Apoptosis of Tumor Cells and Ablation of Mouse Skin Tumors 1

H. Mukhtar, D. Boothman, N. Ahmad, 2000 .

Phthalocyanine 4-photodynamic therapy induces ceramide generation and apoptosis in acid sphingomyelinase-deficient mouse embryonic fibroblasts.

H. Mukhtar, T. Davis, N. Ahmad, 2000, International journal of oncology.

Association of CARD14 Single-Nucleotide Polymorphisms with Psoriasis

N. Ahmad, Arslan Hamid, J. Qureshi, 2022, International journal of molecular sciences.

SIRT1 is upregulated in cutaneous T-cell lymphoma, and its inhibition induces growth arrest and apoptosis

G. Wood, M. Nihal, N. Ahmad, 2014, Cell cycle.

Blockade in Castration-Resistant Prostate Cancer Plk 1 Inhibition Enhances the Efficacy of Androgen Signaling

S. Kuang, T. Ratliff, N. Ahmad, 2014 .

SIRT6 histone deacetylase functions as a potential oncogene in human melanoma

N. Ahmad, C. Singh, Wei Huang, 2017, Genes & cancer.

Ornithine Decarboxylase in Vivo Inhibition of Testosterone-mediated Induction of Prostate Cancer Chemoprevention by Green Tea : In Vitro and Updated Version

R. Mohan, H. Mukhtar, N. Ahmad, 2000 .

Chemoprevention of prostate carcinogenesis by alpha-difluoromethylornithine in TRAMP mice.

S. Gupta, G. MacLennan, H. Mukhtar, 2000, Cancer research.

Mechanism of ultraviolet B-induced cell cycle arrest in G2/M phase in immortalized skin keratinocytes with defective p53.

H. Mukhtar, J. Gautier, A. Kim, 2000, Biochemical and biophysical research communications.

Ultraviolet‐B Radiation Causes an Upregulation of Survivin in Human Keratinocytes and Mouse Skin ¶

Y. Shukla, N. Ahmad, M. Aziz, 2004 .

In vitro and in vivo inhibition of epidermal growth factor receptor-tyrosine kinase pathway by photodynamic therapy

H. Mukhtar, N. Ahmad, K. Kalka, 2001, Oncogene.

Role of p53 in the anti-proliferative effects of Sirt1 inhibition in prostate cancer cells

B. Jung-Hynes, N. Ahmad, Brittney D. Jung-Hynes, 2009, Cell cycle.

Activation of telomerase and its association with G1-phase of the cell cycle during UVB-induced skin tumorigenesis in SKH-1 hairless mouse

H. Mukhtar, N. Ahmad, S. Balasubramanian, 1999, Oncogene.

Resveratrol‐based combinatorial strategies for cancer management

N. Ahmad, C. Singh, J. George, 2013, Annals of the New York Academy of Sciences.

Recombinant human tumor necrosis factor alpha does not potentiate cell killing after photodynamic therapy with a silicon phthalocyanine in A431 human epidermoid carcinoma cells.

H. Mukhtar, N. Ahmad, K. Azizuddin, 2001, International journal of oncology.

Botanical antioxidants for chemoprevention of photocarcinogenesis.

V. Adhami, H. Mukhtar, N. Ahmad, 2002, Frontiers in bioscience : a journal and virtual library.

Plk1 Inhibitors in Cancer Therapy: From Laboratory to Clinics

N. Ahmad, Xiaoqi Liu, M. Ndiaye, 2016, Molecular Cancer Therapeutics.

Plk1 Phosphorylation of Mre11 Antagonizes the DNA Damage Response.

J. Li, N. Ahmad, Xiaoqi Liu, 2017, Cancer research.

Fisetin: a dietary antioxidant for health promotion.

H. Mukhtar, N. Ahmad, N. Khan, 2013, Antioxidants & redox signaling.

Differential antiproliferative and apoptotic response of sanguinarine for cancer cells versus normal cells.

S. Gupta, H. Mukhtar, N. Ahmad, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

The grape antioxidant resveratrol for skin disorders: promise, prospects, and challenges.

H. Mukhtar, N. Ahmad, M. Ndiaye, 2011, Archives of biochemistry and biophysics.

Spices as Potent Antioxidants with Therapeutic Potential

Bharat B. Aggarwal, H. Mukhtar, N. Ahmad, 2001 .

Role of p53 and NF-κB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells

H. Mukhtar, M. Agarwal, N. Ahmad, 2003, Oncogene.

Activation of prodeath Bcl-2 family proteins and mitochondrial apoptosis pathway by sanguinarine in immortalized human HaCaT keratinocytes.

V. Adhami, H. Mukhtar, N. Ahmad, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Enhancing the bioavailability of resveratrol by combining it with piperine.

H. Mukhtar, I. Siddiqui, M. Nihal, 2011, Molecular nutrition & food research.

Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate.

Mohammad Saleem, Hasan Mukhtar, Nihal Ahmad, 2006, Cancer research.

What Is New for an Old Molecule? Systematic Review and Recommendations on the Use of Resveratrol

J. Pezzuto, N. Nalini, T. Szekeres, 2011, PloS one.

Resveratrol and cancer: Challenges for clinical translation.

N. Ahmad, C. Singh, M. Ndiaye, 2015, Biochimica et biophysica acta.

Toward New Depigmenting Agents through Repurposing Existing Drugs: Substituted Hydroxyquinolines as Melanogenesis Inhibitors

I. Rayment, N. Ahmad, J. Sgro, 2022 .

Resveratrol–zinc combination for prostate cancer management

N. Ahmad, C. Singh, A. Pitschmann, 2014, Cell cycle.

Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer

Nihal Ahmad, R. Reiter, B. Jung-Hynes, 2010, Journal of pineal research.

Resveratrol-caused apoptosis of human prostate carcinoma LNCaP cells is mediated via modulation of phosphatidylinositol 3′-kinase/Akt pathway and Bcl-2 family proteins

M. Nihal, N. Ahmad, M. Aziz, 2006, Molecular Cancer Therapeutics.

The Circadian Control of Skin and Cutaneous Photodamage †

N. Ahmad, J. Desotelle, Melissa J. Wilking, 2012, Photochemistry and photobiology.

Ultraviolet B exposure activates Stat3 signaling via phosphorylation at tyrosine705 in skin of SKH1 hairless mouse: a target for the management of skin cancer?

H. Ahsan, N. Ahmad, M. Aziz, 2005, Biochemical and biophysical research communications.

Sirtuin deacetylases: A new target for melanoma management

M. Nihal, N. Ahmad, C. Singh, 2014, Cell cycle.

Silencing of polo‐like kinase (Plk) 1 via siRNA causes induction of apoptosis and impairment of mitosis machinery in human prostate cancer cells: implications for the treatment of prostate cancer

Nihal Ahmad, N. Ahmad, Shannon R Reagan-Shaw, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Resveratrol Imparts Photoprotection of Normal Cells and Enhances the Efficacy of Radiation Therapy in Cancer Cells †

H. Mukhtar, N. Ahmad, Shannon R Reagan-Shaw, 2008, Photochemistry and photobiology.

Resveratrol as a Radio-Protective Agent

Y. Shukla, N. Ahmad, Shannon R Reagan-Shaw, 2005 .

Nanochemoprevention: Sustained Release of Bioactive Food Components for Cancer Prevention

Hasan Mukhtar, Nihal Ahmad, Imtiaz A Siddiqui, 2010, Nutrition and cancer.

Oral Consumption of Green Tea Polyphenols Inhibits Insulin-Like Growth Factor-I–Induced Signaling in an Autochthonous Mouse Model of Prostate Cancer

V. Adhami, H. Mukhtar, I. Siddiqui, 2004, Cancer Research.

Introduction

M. Athar, N. Ahmad, 2012 .

The role of polo-like kinase 1 in carcinogenesis: cause or consequence?

N. Ahmad, Xiaoqi Liu, Brian D. Cholewa, 2013, Cancer research.

Numb regulates stability and localization of the mitotic kinase PLK1 and is required for transit through mitosis.

M. Nihal, N. Ahmad, V. Spiegelman, 2012, Cancer research.

Inhibition of Polo-like Kinase 1 (Plk1) Enhances the Antineoplastic Activity of Metformin in Prostate Cancer*

S. Kuang, T. Ratliff, N. Ahmad, 2014, The Journal of Biological Chemistry.

Inhibition of CWR22Rnu1 tumor growth and PSA secretion in athymic nude mice by green and black teas.

V. Adhami, H. Mukhtar, I. Siddiqui, 2006, Carcinogenesis.

Combining p53 stabilizers with metformin induces synergistic apoptosis through regulation of energy metabolism in castration-resistant prostate cancer

N. Ahmad, Xiaoqi Liu, Long Chen, 2016, Cell cycle.

BRAF Inhibitors in Melanoma Management: When Friends Become Foes.

N. Ahmad, G. Chhabra, 2021, The Journal of investigative dermatology.

Resveratrol nanoformulation for cancer prevention and therapy

H. Mukhtar, I. Siddiqui, N. Ahmad, 2015, Annals of the New York Academy of Sciences.

Suppression of UVB-induced phosphorylation of mitogen-activated protein kinases and nuclear factor kappa B by green tea polyphenol in SKH-1 hairless mice

H. Mukhtar, N. Ahmad, F. Afaq, 2003, Oncogene.

Resveratrol causes WAF-1/p21-mediated G(1)-phase arrest of cell cycle and induction of apoptosis in human epidermoid carcinoma A431 cells.

D. Feyes, V. Adhami, H. Mukhtar, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Role of GLI2 transcription factor in growth and tumorigenicity of prostate cells.

S. Thiyagarajan, N. Ahmad, Shannon R Reagan-Shaw, 2007, Cancer research.

Plk1 inhibition enhances the efficacy of gemcitabine in human pancreatic cancer

J. Li, N. Ahmad, Xiaoqi Liu, 2016, Cell cycle.

Pro-Proliferative Function of Mitochondrial Sirtuin Deacetylase SIRT3 in Human Melanoma.

M. Nihal, W. Zhong, N. Ahmad, 2016, The Journal of investigative dermatology.

PLK1 inhibition-based combination therapies for cancer management

N. Ahmad, C. Singh, M. Ndiaye, 2021, Translational oncology.

Protection against malignant conversion in SENCAR mouse skin by all Trans retinoic acid: Inhibition of the ras p21‐processing enzyme farnesyltransferase and Ha‐ras p21 membrane localization

R. Mohan, R. Agarwal, H. Mukhtar, 1996, Molecular carcinogenesis.

Award Number: W81XWH-04-1-0220 TITLE: SANGUINARINE: A NOVEL AGENT AGAINST PROSTATE CANCER

N. Ahmad, 2007 .

kinase inhibitor-cyclin-cyclin-dependent kinase machinery human prostate carcinoma cells via modulation of cyclin Sanguinarine causes cell cycle blockade and apoptosis of Updated

V. Adhami, H. Mukhtar, M. Nihal, 2004 .

Polo‐like kinase (Plk) 1 as a target for prostate cancer management

N. Ahmad, Shannon R Reagan-Shaw, 2005, IUBMB life.

Targeted depletion of Polo-like kinase (Plk) 1 through lentiviral shRNA or a small-molecule inhibitor causes mitotic catastrophe and induction of apoptosis in human melanoma cells.

W. Zhong, N. Ahmad, V. Spiegelman, 2009, The Journal of investigative dermatology.

Ultraviolet-B Radiation Causes an Upregulation of Survivin in Human Keratinocytes and Mouse Skin¶

Y. Shukla, N. Ahmad, A. Ghotra, 2004, Photochemistry and photobiology.

Prevention of Ultraviolet-B Radiation Damage by Resveratrol in Mouse Skin Is Mediated via Modulation in Survivin¶

N. Ahmad, F. Afaq, M. Aziz, 2005, Photochemistry and photobiology.

Immortalized Human HaCaT Keratinocytes Mitochondrial Apoptosis Pathway by Sanguinarine in Activation of Prodeath Bcl-2 Family Proteins and Updated Version

V. Adhami, H. Mukhtar, N. Ahmad, 2003 .

Cell cycle dysregulation by green tea polyphenol epigallocatechin-3-gallate.

H. Mukhtar, N. Ahmad, P. Cheng, 2000, Biochemical and biophysical research communications.

Combination chemoprevention with grape antioxidants.

H. Mukhtar, I. Siddiqui, N. Ahmad, 2016, Molecular nutrition & food research.

PLK1 and NOTCH Positively Correlate in Melanoma and Their Combined Inhibition Results in Synergistic Modulations of Key Melanoma Pathways

Colin N. Dewey, N. Ahmad, C. Singh, 2020, Molecular Cancer Therapeutics.

Small molecule inhibition of polo-like kinase 1 by volasertib (BI 6727) causes significant melanoma growth delay and regression in vivo.

N. Ahmad, Xiaoqi Liu, Wei Huang, 2017, Cancer letters.

Combined inhibition of MEK and Plk1 has synergistic anti-tumor activity in NRAS mutant melanoma

N. Ahmad, C. Posch, M. Sanlorenzo, 2015, The Journal of investigative dermatology.

Novel downstream molecular targets of SIRT1 in melanoma: A quantitative proteomics approach

Raj Kumar, M. Nihal, N. Ahmad, 2014, Oncotarget.

Plk1 inhibition enhances the efficacy of androgen signaling blockade in castration-resistant prostate cancer.

Zhe Zhang, S. Kuang, T. Ratliff, 2014, Cancer research.

Plk 1 Inhibition Enhances the Ef fi cacy of Androgen Signaling Blockade in Castration-Resistant Prostate Cancer

S. Kuang, T. Ratliff, N. Ahmad, 2014 .

Cytochrome P-450 and drug development for skin diseases.

R. Agarwal, H. Mukhtar, N. Ahmad, 1996, Skin pharmacology : the official journal of the Skin Pharmacology Society.

Mechanism of cancer chemopreventive activity of green Tea.

H. Mukhtar, N. Ahmad, Hasan Mukhtar, 1999, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Prognostic significance of metastasis-associated protein S100A4 (Mts1) in prostate cancer progression and chemoprevention regimens in an autochthonous mouse model.

V. Adhami, H. Mukhtar, N. Ahmad, 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

Protective effects of dietary grape against atopic dermatitis-like skin lesions in NC/NgaTndCrlj mice

B. Longley, N. Ahmad, C. Singh, 2023, Frontiers in Immunology.

Effective Prostate Cancer Chemopreventive Intervention with Green Tea Polyphenols in the TRAMP Model Depends on the Stage of the Disease

V. Adhami, H. Mukhtar, I. Siddiqui, 2009, Clinical Cancer Research.

Skin cancer chemopreventive effects of a flavonoid antioxidant silymarin are mediated via impairment of receptor tyrosine kinase signaling and perturbation in cell cycle progression.

R. Agarwal, H. Gali, N. Ahmad, 1998, Biochemical and biophysical research communications.

Plk1 phosphorylation of Numb leads to impaired DNA damage response

N. Ahmad, X. Liu, E. Farah, 2018, Oncogene.

Growth inhibition, cell-cycle dysregulation, and induction of apoptosis by green tea constituent (-)-epigallocatechin-3-gallate in androgen-sensitive and androgen-insensitive human prostate carcinoma cells.

S. Gupta, H. Mukhtar, N. Ahmad, 2000, Toxicology and applied pharmacology.

Protective Effect of Sanguinarine on Ultraviolet B‐mediated Damages in SKH‐1 Hairless Mouse Skin: Implications for Prevention of Skin Cancer

H. Ahsan, H. Mukhtar, N. Ahmad, 2007, Photochemistry and photobiology.

Regulation of mitosis via mitotic kinases: new opportunities for cancer management.

N. Ahmad, Travis L. Schmit, 2008, Molecular cancer therapeutics.

Regulation of mitosis via mitotic kinases: new opportunities for cancer management

N. Ahmad, Travis L. Schmit, 2007, Molecular Cancer Therapeutics.

Identification of Molecular Targets of Dietary Grape-Mediated Chemoprevention of Ultraviolet B Skin Carcinogenesis: A Comparative Quantitative Proteomics Analysis.

N. Ahmad, C. Singh, G. Barrett-Wilt, 2019, Journal of proteome research.

Large-Scale Label-Free Comparative Proteomics Analysis of Polo-Like Kinase 1 Inhibition via the Small-Molecule Inhibitor BI 6727 (Volasertib) in BRAFV600E Mutant Melanoma Cells

N. Ahmad, C. Scarlett, Brian D. Cholewa, 2014, Journal of proteome research.

Prostate cancer chemoprevention by natural agents: Clinical evidence and potential implications.

N. Ahmad, C. Singh, M. Ndiaye, 2018, Cancer letters.

Microfluidic-integrated patterned ITO immunosensor for rapid detection of prostate-specific membrane antigen biomarker in prostate cancer.

S. Gunasekaran, N. Ahmad, J. Warrick, 2017, Biosensors & bioelectronics.

Circadian rhythm connections to oxidative stress: implications for human health.

H. Mukhtar, N. Ahmad, M. Ndiaye, 2013, Antioxidants & redox signaling.

Green tea polyphenol epigallocatechin-3-gallate differentially modulates nuclear factor kappaB in cancer cells versus normal cells.

S. Gupta, H. Mukhtar, N. Ahmad, 2000, Archives of biochemistry and biophysics.

Electrochemical detection of mobile zinc ions for early diagnosis of prostate cancer

S. Gunasekaran, N. Ahmad, Omer Sadak, 2019, Journal of Electroanalytical Chemistry.

SIRT1 controls circadian clock circuitry and promotes cell survival: a connection with age‐related neoplasms

B. Jung-Hynes, N. Ahmad, Brittney Jung‐Hynes, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Mitochondrial Sirtuins in Skin and Skin Cancers

N. Ahmad, C. Singh, M. Ndiaye, 2020, Photochemistry and photobiology.

Whole Fruit Phytochemicals Combating Skin Damage and Carcinogenesis

N. Ahmad, C. Singh, Charlotte A. Mintie, 2019, Translational oncology.

Enhancement of UVB radiation–mediated apoptosis by sanguinarine in HaCaT human immortalized keratinocytes

N. Ahmad, Shannon R Reagan-Shaw, Jorien Breur, 2006, Molecular Cancer Therapeutics.

Role of intrinsically disordered protein regions/domains in transcriptional regulation.

Raj Kumar, N. Ahmad, Anna M. S. Garza, 2009, Life sciences.

Upregulation of E2F transcription factors in chemically induced mouse skin tumors.

H. Mukhtar, N. Ahmad, S. Balasubramanian, 1999, International journal of oncology.

Molecular targets for green tea in prostate cancer prevention.

V. Adhami, H. Mukhtar, N. Ahmad, 2003, The Journal of nutrition.

Anti-melanoma effects of concomitant inhibition of SIRT1 and SIRT3 in BrafV600E/PtenNULL mice.

K. Iczkowski, N. Ahmad, C. Singh, 2021, The Journal of investigative dermatology.

Role of the retinoblastoma (pRb)-E2F/DP pathway in cancer chemopreventive effects of green tea polyphenol epigallocatechin-3-gallate.

V. Adhami, H. Mukhtar, N. Ahmad, 2002, Archives of biochemistry and biophysics.

Naturally occurring organic osmolytes: From cell physiology to disease prevention

F. Ahmad, Raj Kumar, N. Ahmad, 2010, IUBMB life.

Centriole Overduplication is the Predominant Mechanism Leading to Centrosome Amplification in Melanoma

M. Burkard, B. Longley, M. Nihal, 2018, Molecular Cancer Research.

PLK4 is upregulated in prostate cancer and its inhibition reduces centrosome amplification and causes senescence

K. Iczkowski, M. Nihal, N. Ahmad, 2022, The Prostate.

Selenium and Vitamin E for Prostate Cancer: Post-SELECT (Selenium and Vitamin E Cancer Prevention Trial) Status

H. Mukhtar, Raj Kumar, B. Jung-Hynes, 2011, Molecular medicine.

Steroid hormone receptors in cancer development: a target for cancer therapeutics.

Raj Kumar, N. Ahmad, 2011, Cancer letters.

Grape Chemopreventive Agents Against Angiogenesis and Metastasis

N. Ahmad, C. Singh, Charlotte A. Mintie, 2020 .

Molecular Carcinogenesis

M. Nihal, N. Ahmad, C. Singh, 2019 .

Cancer chemoprevention: future holds in multiple agents.

H. Mukhtar, N. Ahmad, 1999, Toxicology and applied pharmacology.

Genetic Manipulation of Sirtuin 3 Causes Alterations of Key Metabolic Regulators in Melanoma

Hao Chang, M. Nihal, N. Ahmad, 2021, Frontiers in Oncology.

Expression profile of SIRT2 in human melanoma and implications for sirtuin-based chemotherapy

N. Ahmad, Wei Huang, M. Ndiaye, 2017, Cell cycle.

Abstract 539: Pro-proliferative function of the histone deacetylase SIRT3 in prostate cancer

K. Iczkowski, M. Nihal, N. Ahmad, 2018, Molecular and Cellular Biology / Genetics.

Mitochondrial Sirtuins in Cancer: Emerging Roles and Therapeutic Potential.

N. Ahmad, J. George, 2016, Cancer research.

Melatonin resynchronizes dysregulated circadian rhythm circuitry in human prostate cancer cells

B. Jung-Hynes, N. Ahmad, Wei Huang, 2010, Journal of pineal research.

Nitric oxide synthase and skin tumor promotion.

R. Agarwal, H. Mukhtar, N. Ahmad, 1997, Biochemical and biophysical research communications.

Combination of vitamin E and selenium causes an induction of apoptosis of human prostate cancer cells by enhancing Bax/Bcl‐2 ratio

H. Ahsan, H. Mukhtar, M. Nihal, 2008, The Prostate.

Botanical antioxidants for chemoprevention of photocarcinogenesis.

V. Adhami, H. Mukhtar, N. Ahmad, 2002, Frontiers in bioscience : a journal and virtual library.

Sanguinarine induces apoptosis of human pancreatic carcinoma AsPC-1 and BxPC-3 cells via modulations in Bcl-2 family proteins.

H. Ahsan, N. Ahmad, Shannon R Reagan-Shaw, 2007, Cancer letters.

RNA interference-mediated depletion of phosphoinositide 3-kinase activates forkhead box class O transcription factors and induces cell cycle arrest and apoptosis in breast carcinoma cells.

N. Ahmad, Shannon R Reagan-Shaw, 2006, Cancer research.

Nutritional Genomics in Cancer Processes Molecular Targets for Green Tea in Prostate Cancer Prevention 1 , 2

V. Adhami, H. Mukhtar, N. Ahmad, 2003 .

NOTCH signaling is activated in and contributes to resistance in enzalutamide-resistant prostate cancer cells

Lang Li, P. Pascuzzi, T. Ratliff, 2019, The Journal of Biological Chemistry.

Toxicology of the skin: new and emerging concepts

H. Mukhtar, N. Ahmad, 2004 .

Sanguinarine: A Novel Agent Against Prostate Cancer

N. Ahmad, 2005 .

Chemoprevention of prostate carcinogenesis by α-difluoromethylornithine in TRAMP mice

G. MacLennan, H. Mukhtar, N. Ahmad, 2000 .

Analysis of Zinc-Exporters Expression in Prostate Cancer

K. Iczkowski, I. Siddiqui, N. Ahmad, 2016, Scientific Reports.

Antioxidants in chemoprevention of skin cancer.

H. Mukhtar, S. Katiyar, N. Ahmad, 2001, Current problems in dermatology.

Trichloroisocyanuric Acid, A Swimming Pool Disinfectant: New Developments and Role in UV‐Induced Skin Inflammation †

N. Ahmad, G. Chhabra, 2022, Photochemistry and photobiology.

Recent Advancements on Immunomodulatory Mechanisms of Resveratrol in Tumor Microenvironment

N. Ahmad, C. Singh, G. Chhabra, 2021, Molecules.

Role of Polo-Like Kinase 4 (PLK4) in Epithelial Cancers and Recent Progress in its Small Molecule Targeting for Cancer Management

N. Ahmad, M. Ndiaye, G. Chhabra, 2021, Molecular Cancer Therapeutics.

Chemoprotective Effects of Dietary Grape Powder on UVB Radiation-Mediated Skin Carcinogenesis in SKH-1 Hairless Mice.

N. Ahmad, C. Singh, M. Ndiaye, 2019, The Journal of investigative dermatology.

Protective Effects of Dietary Grape on UVB-Mediated Cutaneous Damages and Skin Tumorigenesis in SKH-1 Mice

J. Eickhoff, N. Ahmad, C. Singh, 2020, Cancers.

Targeted knockdown of polo-like kinase 1 alters metabolic regulation in melanoma.

N. Ahmad, C. Singh, M. Ndiaye, 2017, Cancer letters.

Targeting Multiple Signaling Pathways by Green Tea

H. Mukhtar, N. Ahmad, F. Afaq, 2006 .

Antioxidants meet molecular targets for cancer prevention and therapeutics.

H. Mukhtar, N. Ahmad, 2013, Antioxidants & redox signaling.

Abstract 3516: The mitochondrial sirtuin SIRT3 promotes survival of human melanoma cells in vitro

M. Nihal, N. Ahmad, C. Singh, 2014 .

SIRT1 controls circadian clock circuitry and promotes cell survival: a connection with age‐related neoplasms

N. Ahmad, Brittney D. Jung-Hynes, 2009, The FASEB Journal.

Resveratrol‐based combinatorial strategies for cancer management

N. Ahmad, C. Singh, J. George, 2013, Annals of the New York Academy of Sciences.

DNA Damage Response-Independent Role for MDC1 in Maintaining Genomic Stability

C. Carlock, N. Ahmad, Xiaoqi Liu, 2017, Molecular and Cellular Biology.

Numb regulates stability and localization of the mitotic kinase PLK1 and is required for transit through mitosis.

M. Nihal, N. Ahmad, V. Spiegelman, 2012, Cancer research.

Abstract 1133: Plk1 phosphorylation of PTEN causes a tumor-promoting metabolic state

J. Li, S. Kuang, P. Bi, 2015 .

Involvement of Nitric Oxide during Phthalocyanine ( Pc 4 ) Photodynamic Therapy-mediated Apoptosis 1

Sanjay, Gupta, H. Mukhtar, 2006 .

Low-dose arsenic-mediated metabolic shift is associated with activation of Polo-like kinase 1 (Plk1)

N. Ahmad, Xiaoqi Liu, K. Strebhardt, 2015, Cell cycle.