A. Firth

发表

Inhibition of mTOR attenuates store-operated Ca2+ entry in cells from endarterectomized tissues of patients with chronic thromboembolic pulmonary hypertension.

P. Thistlethwaite, A. Ogawa, A. Firth, 2009, American journal of physiology. Lung cellular and molecular physiology.

Ion Channels and Transporters in the Pulmonary Vasculature: A Focus on Smooth Muscle

A. Firth, J. Yuan, 2011 .

Adenylyl cyclase 6 improves calcium uptake and left ventricular function in aged hearts.

A. Firth, J. Yuan, M. Gao, 2011, Journal of the American College of Cardiology.

Inhibitory effect of the tricyclic antidepressant amitriptyline on voltage‐dependent K+ channels in rabbit coronary arterial smooth muscle cells

J. Lee, K. Ha, A. Firth, 2018, Clinical and experimental pharmacology & physiology.

TRP channels in hypertension.

A. Firth, J. Yuan, C. V. Remillard, 2007, Biochimica et biophysica acta.

Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells

F. Gage, I. Verma, A. Firth, 2014, Proceedings of the National Academy of Sciences.

Prednisolone inhibits PDGF-induced nuclear translocation of NF-kappaB in human pulmonary artery smooth muscle cells.

A. Ogawa, A. Firth, W. Yao, 2008, American journal of physiology. Lung cellular and molecular physiology.

Grp78 Loss in Epithelial Progenitors Reveals an Age-Linked Role for ER Stress in Pulmonary Fibrosis.

A. Firth, P. Minoo, Amy S. Lee, 2019, American journal of respiratory and critical care medicine.

The anti‐diabetic drug dapagliflozin induces vasodilation via activation of PKG and Kv channels

J. Lee, Won‐Kyo Jung, A. Firth, 2018, Life sciences.

arterial hypertension smooth muscle cells from patients with pulmonary Upregulation of Oct-4 isoforms in pulmonary artery

A. Ogawa, A. Firth, W. Yao, 2016 .

Upregulation of Oct-4 isoforms in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension.

A. Ogawa, A. Firth, W. Yao, 2010, American journal of physiology. Lung cellular and molecular physiology.

Upregulation of Oct4 isoforms in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension

A. Ogawa, A. Firth, W. Yao, 2010 .

Animal models of pulmonary hypertension: Rho kinase inhibition.

A. Firth, I. Choi, W. Park, 2012, Progress in biophysics and molecular biology.

Functional characterization of voltage-gated K+ channels in mouse pulmonary artery smooth muscle cells.

A. Firth, J. Yuan, O. Platoshyn, 2007, American journal of physiology. Cell physiology.

hypertensionwith chronic thromboembolic pulmonary ) in endarterectomized tissue of + Flk-1 + CD133 + (CD34of putative endothelial progenitor cells

A. Ogawa, A. Firth, M. Madani, 2016 .

Identification of putative endothelial progenitor cells (CD34+CD133+Flk-1+) in endarterectomized tissue of patients with chronic thromboembolic pulmonary hypertension.

P. Thistlethwaite, A. Ogawa, A. Firth, 2009, American journal of physiology. Lung cellular and molecular physiology.

Thrombin-mediated increases in cytosolic [Ca2+] involve different mechanisms in human pulmonary artery smooth muscle and endothelial cells.

A. Firth, J. Yuan, C. V. Remillard, 2008, American journal of physiology. Lung cellular and molecular physiology.

Thrombin-mediated increases in cytosolic [Ca2+] involve different mechanisms in human pulmonary artery smooth muscle and endothelial cells

A. Firth, J. Yuan, C. V. Remillard, 2006 .

Direct effect of protein kinase C inhibitors on cardiovascular ion channels.

A. Firth, W. Park, Y. Son, 2011, BMB reports.

Blockade of voltage-dependent K+ current in rabbit coronary arterial smooth muscle cells by the tricyclic antidepressant clomipramine.

J. Lee, K. Ha, A. Firth, 2018, Journal of Pharmacological Sciences.

Inhibition of the voltage‐dependent K+ current by the class Ic antiarrhythmic drug flecainide in rabbit coronary arterial smooth muscle cells

Won‐Kyo Jung, K. Ha, A. Firth, 2018, Clinical and experimental pharmacology & physiology.

The selective serotonin reuptake inhibitor dapoxetine inhibits voltage‐dependent K+ channels in rabbit coronary arterial smooth muscle cells

Won‐Kyo Jung, K. Ha, A. Firth, 2017, Clinical and experimental pharmacology & physiology.

The PPAR&agr; activator fenofibrate inhibits voltage‐dependent K+ channels in rabbit coronary arterial smooth muscle cells

Won‐Kyo Jung, K. Ha, A. Firth, 2017, European journal of pharmacology.

Nortriptyline, a tricyclic antidepressant, inhibits voltage-dependent K+ channels in coronary arterial smooth muscle cells

K. Ha, A. Firth, I. Choi, 2017, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.

The Effects of the Selective Serotonin Reuptake Inhibitor Fluvoxamine on Voltage-Dependent K(+) Channels in Rabbit Coronary Arterial Smooth Muscle Cells.

Won‐Kyo Jung, A. Firth, I. Choi, 2015, Biological & pharmaceutical bulletin.

W-7 inhibits voltage-dependent K(+) channels independent of calmodulin activity in rabbit coronary arterial smooth muscle cells.

Won‐Kyo Jung, A. Firth, I. Choi, 2015, European journal of pharmacology.

pulmonary but not mesenteric circulation channel-mediated regulation of cellular excitability in v Cellular localization of mitochondria contributes to K

S. Smirnov, A. Firth, D. Gordienko, 2012 .

Pathophysiology of voltage-gated K+ channels in vascular smooth muscle cells: modulation by protein kinases.

Jin Han, A. Firth, J. Yuan, 2010, Progress in biophysics and molecular biology.

Cellular localization of mitochondria contributes to Kv channel-mediated regulation of cellular excitability in pulmonary but not mesenteric circulation

S. Smirnov, A. Firth, D. Gordienko, 2008, American journal of physiology. Lung cellular and molecular physiology.

Bringing down the ROS: a new therapeutic approach for PPHN.

A. Firth, J. Yuan, 2008, American journal of physiology. Lung cellular and molecular physiology.

The anti-diabetic drug repaglinide induces vasorelaxation via activation of PKA and PKG in aortic smooth muscle.

Won‐Kyo Jung, K. Ha, A. Firth, 2016, Vascular pharmacology.

Patho-, physiological roles of voltage-dependent K+ channels in pulmonary arterial smooth muscle cells.

Jin Han, A. Firth, W. Park, 2010, Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi.

Adenylyl Cyclase Type 6 Deletion Decreases Left Ventricular Function via Impaired Calcium Handling

A. Firth, J. Yuan, M. Gao, 2008, Circulation.

Hypoxia Selectively Inhibits KCNA5 Channels in Pulmonary Artery Smooth Muscle Cells

A. Firth, F. Powell, E. Brevnova, 2009, Annals of the New York Academy of Sciences.

Brief Report: Efficient Generation of Hematopoietic Precursors and Progenitors from Human Pluripotent Stem Cell Lines

F. Gage, K. Brennand, J. C. Belmonte, 2011, Stem cells.

Beneficial Effects of Adenylyl Cyclase Type 6 (AC6) Expression Persist Using a Catalytically Inactive AC6 Mutant

A. Firth, J. Yuan, A. Miyanohara, 2011, Molecular Pharmacology.

Idiopathic pulmonary arterial hypertension

A. Firth, J. Yuan, J. Mandel, 2010, Disease Models & Mechanisms.

REGULATION OF PULMONARY VASOCONSTRICTION BY AGONISTS AND CAVEOLAE

P. Insel, A. Firth, J. Yuan, 2008, Experimental lung research.

Chronic exposure to fibrin and fibrinogen differentially regulates intracellular Ca2+ in human pulmonary arterial smooth muscle and endothelial cells.

A. Firth, J. Yuan, T. Morris, 2009, American journal of physiology. Lung cellular and molecular physiology.

The Role of Stem Cells in Vascular Remodeling in CTEPH

A. Firth, J. Yuan, 2015 .

Grp78 Loss in Epithelial Progenitors Reveals an Age-linked Role for Endoplasmic Reticulum Stress in Pulmonary Fibrosis

A. Firth, P. Minoo, Amy S. Lee, 2019 .

Models and Open Questions Pulmonary Surfactant Pathophysiology: Current

Kevin J. McHugh, J. Alcorn, Jianhua Fu, 2015 .

PDGF enhances store-operated Ca2+ entry by upregulating STIM1/Orai1 via activation of Akt/mTOR in human pulmonary arterial smooth muscle cells.

A. Ogawa, A. Firth, J. Yuan, 2012, American journal of physiology. Cell physiology.

Lymphoid regeneration from gene-corrected SCID-X1 subject-derived iPSCs.

I. Verma, I. Alexander, A. Firth, 2015, Cell stem cell.

Lymphoid Regeneration fr om Gene-Corrected SCID-X 1 Subject-Derived iPSCs Graphical Abstract Highlights

I. Verma, I. Alexander, A. Firth, 2015 .

Mitochondria-dependent regulation of Kv currents in rat pulmonary artery smooth muscle cells

S. Smirnov, A. Firth, K. Yuill, 2008, American journal of physiology. Lung cellular and molecular physiology.

Increased sensitivity of serotonin on the voltage-dependent K+ channels in mesenteric arterial smooth muscle cells of OLETF rats.

Jin Han, Jae-Hong Ko, A. Firth, 2010, Progress in biophysics and molecular biology.

The Hope for iPSC in Lung Stem Cell Therapy and Disease Modeling

A. Firth, Tushar Menon, 2015 .

Inhibition of the Voltage-Dependent K+ Current by the Tricyclic Antidepressant Desipramine in Rabbit Coronary Arterial Smooth Muscle Cells

Won‐Kyo Jung, K. Ha, A. Firth, 2018, Cardiovascular Toxicology.

ES cell potency fluctuates with endogenous retrovirus activity

Shawn P. Driscoll, Helen M. Rowe, S. Pfaff, 2012, Nature.

Endothelial and smooth muscle cell ion channels in pulmonary vasoconstriction and vascular remodeling.

A. Firth, J. Yuan, A. Makino, 2011, Comprehensive Physiology.

CLDN18.1 attenuates malignancy and related signaling pathways of lung adenocarcinoma in vivo and in vitro

B. Frenkel, N. Chimge, A. Firth, 2018, International journal of cancer.

Adult Lung Stem Cells

A. Firth, J. Yuan, Ruby A. Fernandez, 2014 .

Regulation of Ca2+ Signaling in Pulmonary Hypertension

A. Firth, W. Park, J. Won, 2013, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.

Side-effects of protein kinase inhibitors on ion channels

A. Firth, W. Park, Hongzoo Park, 2013, Journal of Biosciences.

Alterations of voltage‐dependent K+ channels in the mesenteric artery during the early and chronic phases of diabetes

K. Ha, A. Firth, Seok-Ho Hong, 2016, Clinical and experimental pharmacology & physiology.

Functional Gene Correction for Cystic Fibrosis in Lung Epithelial Cells Generated from Patient iPSCs.

F. Gage, I. Verma, A. Firth, 2015, Cell reports.

Identification of functional progenitor cells in the pulmonary vasculature

J. Yuan, A. Firth, 2012, Pulmonary circulation.

Establishment of the early cilia preassembly protein complex during motile ciliogenesis

A. Ustione, D. Piston, S. Brody, 2018, Proceedings of the National Academy of Sciences.

Hypoxia divergently regulates production of reactive oxygen species in human pulmonary and coronary artery smooth muscle cells.

Winnie Wu, A. Firth, J. Yuan, 2007, American journal of physiology. Lung cellular and molecular physiology.

Multipotent mesenchymal progenitor cells are present in endarterectomized tissues from patients with chronic thromboembolic pulmonary hypertension.

A. Ogawa, A. Firth, W. Yao, 2010, American journal of physiology. Cell physiology.

Thrombin‐mediated activation of Akt signaling contributes to pulmonary vascular remodeling in pulmonary hypertension

I. Yamadori, D. Fraidenburg, A. Ogawa, 2013, Physiological reports.

Intermittent Reprogramming: A Breath of Fresh Air for Lung Regeneration.

A. Firth, 2017, Cell Stem Cell.

Functional ion channels in human pulmonary artery smooth muscle cells: Voltage-dependent cation channels

I. Fantozzi, A. Firth, J. Yuan, 2002, Pulmonary circulation.

Selective serotonin reuptake inhibitor sertraline inhibits voltage-dependent K+ channels in rabbit coronary arterial smooth muscle cells

A. Firth, I. Choi, W. Park, 2016, Journal of Biosciences.

The vasorelaxant effect of mitiglinide via activation of voltage-dependent K+ channels and SERCA pump in aortic smooth muscle.

K. Ha, A. Firth, I. Choi, 2017, Life sciences.

Activated expression of cardiac adenylyl cyclase 6 reduces dilation and dysfunction of the pressure-overloaded heart.

A. Firth, J. Yuan, M. Gao, 2011, Biochemical and biophysical research communications.

"Ether-à-go-go" proliferation of iPSC-derived mesenchymal stem cells. Focus on "Regulation of cell proliferation of human induced pluripotent stem cell-derived mesenchymal stem cells via ether-à-go-go 1 (hEAG1) potassium channel".

A. Firth, J. Yuan, 2012, American journal of physiology. Cell physiology.

Side-effects of protein kinase inhibitors on ion channels

A. Firth, W. Park, Hongzoo Park, 2013, Journal of Biosciences.

Identification of Adult Stem and Progenitor Cells in the Pulmonary Vasculature

A. Firth, W. Yao, J. Yuan, 2011 .

Y-27632, a Rho-Associated Protein Kinase Inhibitor, Inhibits Voltage-Dependent K+ Channels in Rabbit Coronary Arterial Smooth Muscle Cells

Won‐Kyo Jung, K. Ha, A. Firth, 2016, Pharmacology.

Fine tuning ICRAC: the interactions of STIM‐1 and Orai

A. Firth, 2009, The Journal of physiology.

Lung Stem Cells in the Epithelium and Vasculature

Jason X.-J. Yuan, A. Firth, J. Yuan, 2015, Stem Cell Biology and Regenerative Medicine.

Multipotent mesenchymal progenitor cells are present in endarterectomized tissues from patients with chronic thromboembolic pulmonary hypertension.

A. Ogawa, A. Firth, W. Yao, 2010, American journal of physiology. Cell physiology.

PDGF enhances store-operated Ca2+ entry by upregulating STIM1/Orai1 via activation of Akt/mTOR in human pulmonary arterial smooth muscle cells.

A. Ogawa, A. Firth, J. Yuan, 2012, American journal of physiology. Cell physiology.