I. Shin

发表

Down‐regulation of Notch‐dependent transcription by Akt in vitro

Jieun Song, Sungwoo Park, Minsoon Kim, 2008, FEBS letters.

PKB/Akt mediates cell-cycle progression by phosphorylation of p27Kip1 at threonine 157 and modulation of its cellular localization

Carlos L. Arteaga, J. Baselga, F. Rojo, 2002, Nature Medicine.

Akt isoform-specific inhibition of MDA-MB-231 cell proliferation.

Kyung-Min Lee, I. Shin, Wonseok Yang, 2011, Cellular signalling.

12-O-Tetradecanoyl phorbol-13-acetate (TPA)-induced growth arrest is increased by silibinin by the down-regulation of cyclin B1 and cdc2 and the up-regulation of p21 expression in MDA-MB231 human breast cancer cells.

Jeong Eon Lee, J. Lee, Sangmin Kim, 2010, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Effect of p 27 on motility of MDA-MB-231 breast cancer cells

I. Shin, Wonseok Yang, Eun Y. Lee, 2022 .

Toxicological assessment of phthalates and their alternatives using human keratinocytes.

I. Shin, Hyungjoo Kim, K. Nam, 2019, Environmental research.

The alkaloid Berberine inhibits the growth of Anoikis-resistant MCF-7 and MDA-MB-231 breast cancer cell lines by inducing cell cycle arrest.

W. Han, D. Noh, S. Y. Park, 2010, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Roles of RhoA and phospholipase A2 in the elevation of intracellular H2O2 by transforming growth factor-beta in Swiss 3T3 fibroblasts.

S. H. Lee, K. Ha, I. Shin, 1999, Cellular signalling.

Role of the CCN protein family in cancer

I. Shin, Hyungjoo Kim, Seog-ho Son, 2018, BMB reports.

Protein kinase B/Akt1 inhibits autophagy by down-regulating UVRAG expression.

Kyung-Min Lee, I. Shin, Wonseok Yang, 2013, Experimental cell research.

HER2 stabilizes survivin while concomitantly down-regulating survivin gene transcription by suppressing Notch cleavage.

D. Noh, Kyung-Min Lee, I. Shin, 2013, The Biochemical journal.

S100A4 negatively regulates β-catenin by inducing the Egr-1-PTEN-Akt-GSK3β degradation pathway.

Kyung-Min Lee, I. Shin, Wonseok Yang, 2014, Cellular signalling.

Title : Cross-linking of CD 24 inhibits growth of MCF-7 breast cancer cells

W. Han, D. Noh, J. Lee, 2007 .

Transforming growth factor {beta} (TGF-{beta})-Smad target gene protein tyrosine phosphatase receptor type kappa is required for TGF-{beta} function.

Frederick Y. Wu, C. Arteaga, I. Shin, 2005, Molecular and cellular biology.

Glycogen synthase kinase 3-β phosphorylates novel S/T-P-S/T domains in Notch1 intracellular domain and induces its nuclear localization.

I. Shin, Ji-hyun Ju, Xiangzi Han, 2012, Biochemical and biophysical research communications.

Mass Cytometry and Single-Cell RNA-seq Profiling of the Heterogeneity in Human Peripheral Blood Mononuclear Cells Interacting with Silver Nanoparticles.

I. Shin, T. Yoon, Yangsoon Lee, 2020, Small.

Proapoptotic activity of cell-permeable anti-Akt single-chain antibodies.

C. Arteaga, I. Shin, R. Mernaugh, 2005, Cancer research.

Binding of galectin-1 to integrin β1 potentiates drug resistance by promoting survivin expression in breast cancer cells

D. Noh, Sangmin Kim, I. Shin, 2017, Oncotarget.

Absence of a Human DnaJ Protein hTid-1S Correlates with Aberrant Actin Cytoskeleton Organization in Lesional Psoriatic Skin*

Jeung-Hoon Lee, I. Shin, C. Joe, 2012, The Journal of Biological Chemistry.

Reduction of cytosolic p27(Kip1) inhibits cancer cell motility, survival, and tumorigenicity.

Frederick Y. Wu, J. Baselga, F. Rojo, 2006, Cancer research.

Berberine Inhibits Growth of the Breast Cancer Cell Lines MCF-7 and MDA-MB-231

Jeong Eon Lee, W. Han, D. Noh, 2008, Planta medica.

Phosphorylation of p27Kip1 at Thr-157 Interferes with Its Association with Importin α during G1 and Prevents Nuclear Re-entry*

Frederick Y. Wu, C. Arteaga, I. Shin, 2005, Journal of Biological Chemistry.

Regulation of Cell Proliferation and Migration by Keratin19-Induced Nuclear Import of Early Growth Response-1 in Breast Cancer Cells

I. Chu, Kyung-Min Lee, I. Shin, 2013, Clinical Cancer Research.

Comparative toxicological evaluation of nonylphenol and nonylphenol polyethoxylates using human keratinocytes

I. Shin, M. Gye, Hyungjoo Kim, 2018, Drug and chemical toxicology.

Effects of Endocrine Disruptors on Bombina orientalis P450 Aromatase Activity

Kyung-Min Lee, I. Shin, Wonseok Yang, 2010, Zoological science.

Silencing of Glut1 induces chemoresistance via modulation of Akt/GSK-3β/β-catenin/survivin signaling pathway in breast cancer cells.

I. Shin, Hyungjoo Kim, K. Nam, 2017, Archives of biochemistry and biophysics.

Apigenin induces apoptosis via extrinsic pathway, inducing p53 and inhibiting STAT3 and NFκB signaling in HER2-overexpressing breast cancer cells

I. Shin, J. Woo, Sang-Yoon Park, 2012, Molecular and Cellular Biochemistry.

Cytotoxicity measurement of Bisphenol A (BPA) and its substitutes using human keratinocytes

I. Shin, M. Gye, Hyungjoo Kim, 2018, Environmental research.

Down-regulation of estrogen receptor α (ERα) transcriptional activity by p27 is mediated by inhibition of ERα nuclear localization and modulation of the ERα transcriptional complex.

I. Shin, Wonseok Yang, Min Jeong Jeon, 2012, Cellular signalling.

Berberine Diminishes the Side Population and ABCG2 Transporter Expression in MCF-7 Breast Cancer Cells

W. Han, D. Noh, I. Shin, 2008, Planta medica.

Glioblastoma‐educated mesenchymal stem‐like cells promote glioblastoma infiltration via extracellular matrix remodelling in the tumour microenvironment

Ki-Chun Yoo, Su-Jae Lee, I. Shin, 2022, Clinical and translational medicine.

Expression of active Akt protects against tamoxifen‐induced apoptosis in MCF‐7 Cells

C. Arteaga, I. Shin, 2006, IUBMB life.

Effect of p27 on motility of MDA-MB-231 breast cancer cells.

I. Shin, Wonseok Yang, Eun Y. Lee, 2009, Oncology reports.

D609-sensitive tyrosine phosphorylation is involved in Fas-mediated phospholipase D activation

I. Shin, Joong-Soo Han, K. Lee, 2001, Experimental & Molecular Medicine.

Lysophosphatidic acid increases intracellular H2O2 by phospholipase D and RhoA in rat-2 fibroblasts.

K. Ha, I. Shin, C. Joe, 1999, Molecules and cells.

Ceramide does not inhibit protein kinase C beta-dependent phospholipase D activity stimulated by anti-Fas monoclonal antibody in A20 cells.

I. Shin, J. Han, 2000, Cellular signalling.

Loss of PTEN/MMAC1/TEP in EGF receptor-expressing tumor cells counteracts the antitumor action of EGFR tyrosine kinase inhibitors

G. Mills, N. Rosen, P. Dennis, 2003, Oncogene.

Brain type of creatine kinase induces doxorubicin resistance via TGF-β signaling in MDA-MB-231 breast cancer cells

I. Shin, K. Nam, Sunhwa Oh, 2022, Animal cells and systems.

Phospholipase D Is Not Involved in Rho A-Mediated Activation of Stress Fiber Formation

K. Ha, S. Leem, I. Shin, 1997 .

Identification and ultrastructural imaging of photodynamic therapy-induced microfilaments by atomic force microscopy.

Se-Hui Jung, K. Ha, I. Shin, 2009, Ultramicroscopy.

Induction of apoptotic cell death by phytoestrogens by up-regulating the levels of phospho-p53 and p21 in normal and malignant estrogen receptor α-negative breast cells.

I. Shin, H. Seo, K. Jang, 2011, Nutrition research.

Differential effects of Fas cross-linking on phospholipase D activation and related lipid metabolism in Fas-resistant A20 cells

I. Shin, Joong-Soo Han, S. Lim, 2002, Experimental & Molecular Medicine.

Fas-mediated activation of phospholipase D is coupled to the stimulation of phosphatidylcholine-specific phospholipase C in A20 cells.

J. Kim, I. Shin, J. Han, 1999, Archives of biochemistry and biophysics.

Cytotoxic Effect of Nano-SiO2 in Human Breast Cancer Cells via Modulation of EGFR Signaling Cascades.

I. Shin, Hyungjoo Kim, K. Nam, 2017, Anticancer research.

Pifithrin-α, an Inhibitor of p53 Transactivation, Up-Regulates COX-2 Expression through an MAPK-Dependent Pathway

J. Lee, Sangmin Kim, I. Shin, 2010, Pharmacology.

Extracellular matrix protein 1 regulates cell proliferation and trastuzumab resistance through activation of epidermal growth factor signaling

Taehoon Lee, Young-Pil Kim, Sei-Hyun Ahn, 2014, Breast Cancer Research.

Correction to: ECM1 regulates cell proliferation and trastuzumab resistance through activation of EGF-signaling

Sung-Bae Kim, D. Noh, S. Ahn, 2019, Breast Cancer Research.

HER2 Overexpression Attenuates the Antiproliferative Effect of Aromatase Inhibitor in MCF-7 Breast Cancer Cells Stably Expressing Aromatase

C. Arteaga, I. Shin, T. Miller, 2009 .

Danshen (Salvia miltiorrhiza) extract inhibits proliferation of breast cancer cells via modulation of Akt activity and p27 level

I. Shin, Wonseok Yang, Min Jeong Jeon, 2009, Phytotherapy research : PTR.

Corepressor MMTR/DMAP1 Is Involved in both Histone Deacetylase 1- and TFIIH-Mediated Transcriptional Repression

I. Shin, J. H. Chae, C. Kim, 2007, Molecular and Cellular Biology.

CD24 regulates stemness and the epithelial to mesenchymal transition through modulation of Notch1 mRNA stability by p38MAPK.

I. Shin, J. Shim, Kyung-min Lee, 2014, Archives of biochemistry and biophysics.

Protein kinase Cδ negatively regulates Notch1-dependent transcription via a kinase-independent mechanism in vitro.

Jieun Song, Minsoon Kim, I. Shin, 2012, Biochimica et biophysica acta.

HER2 Signaling in Breast Cancer.

I. Shin, 2021, Advances in experimental medicine and biology.

Type I Transforming Growth Factor β Receptor Binds to and Activates Phosphatidylinositol 3-Kinase*

Jae Youn Yi, Carlos L Arteaga, C. Arteaga, 2005, Journal of Biological Chemistry.

Aquaporin7 expression during perinatal development of mouse brain

I. Shin, M. Gye, J. E. Lee, 2006, Neuroscience Letters.

Transforming Growth Factor (cid:1) Enhances Epithelial Cell Survival via Akt-dependent Regulation of FKHRL1

A. Brunet, U. Rodeck, C. Arteaga, 2022 .

Rac GTPase activity is essential for EGF-induced mitogenesis.

S. Yi, K. Ha, B. Jhun, 1998, Molecules and cells.

Egr-1 is required for neu/HER2-induced mammary tumors.

I. Shin, Hyungjoo Kim, K. Nam, 2018, Cellular signalling.

CD24 enhances DNA damage-induced apoptosis by modulating NF-κB signaling in CD44-expressing breast cancer cells.

D. Noh, Minsoon Kim, I. Shin, 2011, Carcinogenesis.

CD 24 enhances DNA damage-induced apoptosis by modulating NFk B signaling in CD 44-expressing breast cancer cells

D. Noh, Minsoon Kim, I. Shin, 2011 .

Isolation of CD24(high) and CD24(low/-) cells from MCF-7: CD24 expression is positively related with proliferation, adhesion and invasion in MCF-7.

W. Han, D. Noh, I. Shin, 2007, Cancer letters.

Activated type I TGFβ receptor kinase enhances the survival of mammary epithelial cells and accelerates tumor progression

M. Barcellos-Hoff, C. Arteaga, I. Shin, 2006, Oncogene.

Activated type I TGFbeta receptor (Alk5) kinase confers enhanced survival to mammary epithelial cells and accelerates mammary tumor progression

M. Barcellos-Hoff, C. Arteaga, I. Shin, 2005 .

CD44 regulates cell proliferation, migration, and invasion via modulation of c-Src transcription in human breast cancer cells.

I. Shin, K. Nam, Sunhwa Oh, 2015, Cellular signalling.

Jak2 and Tyk2 are necessary for lineage-specific differentiation, but not for the maintenance of self-renewal of mouse embryonic stem cells.

I. Shin, C. Kim, H. Kang, 2006, Biochemical and biophysical research communications.

ECM1 promotes the Warburg effect through EGF-mediated activation of PKM2.

I. Shin, Taehoon G. Lee, K. Nam, 2015, Cellular signalling.

ECM1 regulates tumor metastasis and CSC-like property through stabilization of β-catenin

I. Shin, J. Lee, K. Nam, 2015, Oncogene.

Ablation of CD44 induces glycolysis-to-oxidative phosphorylation transition via modulation of the c-Src-Akt-LKB1-AMPKα pathway.

I. Shin, K. Nam, Sunhwa Oh, 2016, The Biochemical journal.

Cytokeratin19 induced by HER2/ERK binds and stabilizes HER2 on cell membranes

D. Noh, C. Arteaga, I. Shin, 2014, Cell Death and Differentiation.

Phosphorylation of p90RSK is associated with increased response to neoadjuvant chemotherapy in ER-positive breast cancer

W. Han, D. Noh, H. Moon, 2012, BMC Cancer.

Glut1 promotes cell proliferation, migration and invasion by regulating epidermal growth factor receptor and integrin signaling in triple-negative breast cancer cells

I. Shin, Hyungjoo Kim, K. Nam, 2017, BMB reports.

Ras GTPase is essential for fas-mediated activation of phospholipase D in A20 cells.

I. Shin, J. Han, 2000, Biochemical and biophysical research communications.

YAP, CTGF and Cyr61 are overexpressed in tamoxifen-resistant breast cancer and induce transcriptional repression of ERα.

J. Lee, Sangmin Kim, I. Shin, 2021, Journal of cell science.

CD24 regulates cell proliferation and transforming growth factor β-induced epithelial to mesenchymal transition through modulation of integrin β1 stability.

D. Noh, I. Shin, Wonseok Yang, 2012, Cellular signalling.

TGFβ1 Protects Cells from γ-IR by Enhancing the Activity of the NHEJ Repair Pathway

In-Chul Park, Mary Helen Barcellos-Hoff, Jae Youn Yi, 2014, Molecular Cancer Research.

PTEN sensitizes MDA-MB-468 cells to inhibition of MEK/Erk signaling for the blockade of cell proliferation.

Minsoon Kim, I. Shin, H. Seo, 2010, Oncology reports.

HER2/Neu (ErbB2) signaling to Rac1-Pak1 is temporally and spatially modulated by transforming growth factor beta.

Frederick Y. Wu, C. Arteaga, I. Shin, 2006, Cancer research.

HER 2 / Neu ( ErbB 2 ) Signaling to Rac 1-Pak 1 Is Temporally and Spatially Modulated by Transforming Growth Factor B Shizhen

Frederick Y. Wu, C. Arteaga, I. Shin, 2006 .

Induction of fibronectin by HER2 overexpression triggers adhesion and invasion of breast cancer cells.

Sangmin Kim, I. Shin, S. Nam, 2015, Experimental cell research.

Apigenin induces apoptosis via extrinsic pathway, inducing p53 and inhibiting STAT3 and NFκB signaling in HER2-overexpressing breast cancer cells

I. Shin, J. Woo, Sang-Yoon Park, 2012, Molecular and Cellular Biochemistry.

Induction of apoptotic cell death by Pharbitis nil extract in HER2-overexpressing MCF-7 cells.

I. Shin, Wonseok Yang, Min Jeong Jeon, 2011, Journal of ethnopharmacology.

ErbB Receptor Signaling and Therapeutic Resistance to Aromatase Inhibitors

C. Arteaga, I. Shin, T. Miller, 2006, Clinical Cancer Research.

Phosphatidylcholine-specific phospholipase C-mediated induction of phospholipase D activity in Fas-expressing murine cells.

I. Shin, J. Han, 2000, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

CCN3/NOV promotes metastasis and tumor progression via GPNMB-induced EGFR activation in triple-negative breast cancer

I. Shin, Hyungjoo Kim, Seog-ho Son, 2023, Cell Death & Disease.

The CD49d+/high subpopulation from isolated human breast sarcoma spheres possesses tumor-initiating ability.

W. Han, D. Noh, I. Shin, 2011, International journal of oncology.

Transforming Growth Factor β (TGF-β)-Smad Target Gene Protein Tyrosine Phosphatase Receptor Type Kappa Is Required for TGF-β Function

Frederick Y. Wu, C. Arteaga, I. Shin, 2005, Molecular and Cellular Biology.

Protein expression profiling of primary mammary epithelial cells derived from MMTV‐neu mice revealed that HER2/NEU‐driven changes in protein expression are functionally clustered

D. Noh, Jaeyoon Kim, Sungwoo Park, 2009, IUBMB life.

Elevated STC‑1 augments the invasiveness of triple‑negative breast cancer cells through activation of the JNK/c‑Jun signaling pathway.

Jeonghun Han, Sangmin Kim, Sangmin Kim, 2016, Oncology reports.

CTGF regulates cell proliferation, migration, and glucose metabolism through activation of FAK signaling in triple-negative breast cancer

I. Shin, Hyungjoo Kim, Seog-ho Son, 2021, Oncogene.

Silencing of CD133 inhibits GLUT1‐mediated glucose transport through downregulation of the HER3/Akt/mTOR pathway in colon cancer

I. Shin, Hyungjoo Kim, Seog-ho Son, 2019, FEBS letters.

Akt stabilizes estrogen receptor alpha with the concomitant reduction in its transcriptional activity.

Jieun Song, Sungwoo Park, I. Shin, 2008, Cellular signalling.

CD24 cross-linking induces apoptosis in, and inhibits migration of, MCF-7 breast cancer cells

W. Han, D. Noh, J. Lee, 2008, BMC Cancer.

Mash1 and neurogenin 2 enhance survival and differentiation of neural precursor cells after transplantation to rat brains via distinct modes of action.

I. Shin, H. Koh, Sang-Hun Lee, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

A functional comparison between the HER2high/HER3 and the HER2low/HER3 dimers on heregulin-β1-induced MMP-1 and MMP-9 expression in breast cancer cells

J. Lee, Sangmin Kim, I. Shin, 2012, Experimental & Molecular Medicine.

Phosphatidic Acid-induced Elevation of Intracellular Ca2+ Is Mediated by RhoA and H2O2in Rat-2 Fibroblasts*

K. Ha, S. Leem, I. Shin, 1998, The Journal of Biological Chemistry.

Aromatase is phosphorylated in situ at serine-118

M. Waterman, N. Kagawa, C. Arteaga, 2008, The Journal of Steroid Biochemistry and Molecular Biology.

Colchicine activates actin polymerization by microtubule depolymerization.

K. Ha, I. Shin, H. Jung, 1997, Molecules and cells.

Generation of Dopamine Neurons with Improved Cell Survival and Phenotype Maintenance Using a Degradation-Resistant Nurr1 Mutant

K. Baek, I. Shin, H. Koh, 2009, Stem cells.

Titanium dioxide nanoparticles induce apoptosis by interfering with EGFR signaling in human breast cancer cells.

I. Shin, Hyungjoo Kim, K. Nam, 2019, Environmental research.

EGFR negates the proliferative effect of oncogenic HER2 in MDA-MB-231 cells.

I. Shin, Wonseok Yang, K. Nam, 2015, Archives of biochemistry and biophysics.

Transforming Growth Factor (cid:1) Enhances Epithelial Cell Survival via Akt-dependent Regulation of FKHRL1

A. Brunet, U. Rodeck, C. Arteaga, 2001 .

Acid-induced Elevation of Intracellular Ca 2 1 Is Mediated by RhoA and H 2 O 2 in Rat-2 Fibroblasts *

K. Ha, S. Leem, I. Shin, 1998 .

Corepressor MMTR/DMAP1 is an intrinsic negative regulator of CAK kinase to regulate cell cycle progression.

I. Shin, Youn-Hee Choi, J. H. Chae, 2010, Biochemical and biophysical research communications.

Effects of Ceramide, the Fas Signal Intermediate, on Apoptosis and Phospholipase D Activity in Mouse Ovarian Granulosa Cells in Vitro

I. Shin, Joong-Soo Han, Y. Yoon, 1999, IUBMB life.

Silencing of Glut1 induces chemoresistance via modulation of Akt/GSK-3β/β-catenin/survivin signaling pathway in breast cancer cells.

I. Shin, Hyungjoo Kim, K. Nam, 2017, Archives of biochemistry and biophysics.