Pei-Hsuan Chen

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Decoy Receptor 3 Expression in AsPC-1 Human Pancreatic Adenocarcinoma Cells via the Phosphatidylinositol 3-Kinase-, Akt-, and NF-κB-Dependent Pathway1

Pei-Hsuan Chen, Chia-Ron Yang, 2008, The Journal of Immunology.

Reductive carboxylation supports growth in tumor cells with defective mitochondria

W. Marston Linehan, Navdeep S. Chandel, Pei-Hsuan Chen, 2011, Nature.

Differential contribution of the mitochondrial translation pathway to the survival of diffuse large B-cell lymphoma subsets

M. Shipp, S. Ficarro, J. Marto, 2016, Cell Death and Differentiation.

Activation of CAR and non-CAR T cells within the tumor microenvironment following CAR T-cell therapy.

Stuart A. Sievers, F. Hodi, J. Rossi, 2020, JCI insight.

Autophagy: a promising process for the treatment of acetaminophen-induced liver injury

Pei-Hsuan Chen, Jiao Guo, Z. Su, 2020, Archives of Toxicology.

Metabolic diversity in human non-small cell lung cancer

B. Faubert, R. Deberardinis, J. Minna, 2014, bioRxiv.

Aryl hydrocarbon receptor ligands enhance lung immunity through intestinal IKKβ pathways

Pei-Hsuan Chen, Lee-Wei Chen, Tzyy-Bin Tsay, 2019, Journal of Translational Medicine.

Multiplex Tissue Imaging Harmonization: A Multicenter Experience from CIMAC-CIDC Immuno-Oncology Biomarkers Network

D. Neuberg, I. Wistuba, Catherine J. Wu, 2021, Clinical Cancer Research.

Axicabtagene Ciloleucel in the Non-Trial Setting: Outcomes and Correlates of Response, Resistance, and Toxicity.

Matthew J. Frigault, J. Ritz, D. Maloney, 2020, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Toll-Like Receptor Stimulation Induces Nondefensin Protein Expression and Reverses Antibiotic-Induced Gut Defense Impairment

Ching-mei Hsu, Pei-Hsuan Chen, Lee-Wei Chen, 2014, Infection and Immunity.

Nod2 Mutation Enhances NF-kappaB Activity and Bacterial Killing Activity of Macrophages

Ching-mei Hsu, Pei-Hsuan Chen, Lee-Wei Chen, 2009, Inflammation.

Enteric bacterial loads are associated with interleukin-6 levels in systemic inflammatory response syndrome patients

Pei-Hsuan Chen, Lee-Wei Chen, Jen-Tang Sun, 2016 .

Dead bacteria reverse antibiotic-induced host defense impairment in burns.

Ching-mei Hsu, Pei-Hsuan Chen, Lee-Wei Chen, 2014, Journal of the American College of Surgeons.

TNF-alpha decreases infection-induced lung injury in burn through negative regulation of TLR4/iNOS.

Ching-mei Hsu, Pei-Hsuan Chen, Lee-Wei Chen, 2013, The Journal of surgical research.

Hypertonic Saline Enhances Host Defense and Reduces Apoptosis in Burn Mice by Increasing Toll-Like Receptors

Ching-mei Hsu, Pei-Hsuan Chen, Lee-Wei Chen, 2011, Shock.

Commensal microflora induce host defense and decrease bacterial translocation in burn mice through toll-like receptor 4

Ching-mei Hsu, Pei-Hsuan Chen, Lee-Wei Chen, 2010, Journal of Biomedical Science.

Gut flora enhance bacterial clearance in lung through toll-like receptors 4

Ching-mei Hsu, Pei-Hsuan Chen, Lee-Wei Chen, 2011, Journal of Biomedical Science.

Commensal Microflora Contribute to Host Defense Against Escherichia Coli Pneumonia Through Toll-Like Receptors

Ching-mei Hsu, Pei-Hsuan Chen, Lee-Wei Chen, 2011, Shock.

I&kgr;B-kinase/nuclear factor-&kgr;B signaling prevents thermal injury–induced gut damage by inhibiting c-Jun NH2-terminal kinase activation*

M. Karin, Ching-mei Hsu, Pei-Hsuan Chen, 2007 .

Metabolic diversity in human non-small cell lung cancer

B. Faubert, R. Deberardinis, J. Minna, 2014, bioRxiv.

Blocking TNF-α enhances Pseudomonas aeruginosa-induced mortality in burn mice through induction of IL-1β.

Ching-mei Hsu, Pei-Hsuan Chen, Lee-Wei Chen, 2013, Cytokine.

TLR LIGAND DECREASES MESENTERIC ISCHEMIA AND REPERFUSION INJURY-INDUCED GUT DAMAGE THROUGH TNF-&agr; SIGNALING

Ching-mei Hsu, Pei-Hsuan Chen, Lee-Wei Chen, 2008, Shock.

Lipid sensing by mTOR complexes via de novo synthesis of phosphatidic acid

R. Deberardinis, Pei-Hsuan Chen, D. A. Foster, 2017, The Journal of Biological Chemistry.

Supplementation of endogenous Ahr ligands reverses insulin resistance and associated inflammation in an insulin-dependent diabetic mouse model.

Pei-Hsuan Chen, Lee-Wei Chen, Wen-Chung Liu, 2020, The Journal of nutritional biochemistry.

Adipose-derived stromal cells reverse insulin resistance through inhibition of M1 expression in a type 2 diabetes mellitus mouse model

Pei-Hsuan Chen, Lee-Wei Chen, J. Yen, 2022, Stem cell research & therapy.

Peritonitis-induced peroxynitrite and lung damage depends on c-Jun NH2-terminal kinase signaling of hematopoietic cells

Ching-mei Hsu, Pei-Hsuan Chen, Lee-Wei Chen, 2010, Critical care medicine.

Study on the Effect of Galacto-oligosaccharide (GOS) in Relieving Constipation and Defecating Feces Excretion

Pei-Hsuan Chen, H. Cao, Jiao Guo, 2020, IOP Conference Series: Materials Science and Engineering.

Denbinobin suppresses breast cancer metastasis through the inhibition of Src-mediated signaling pathways.

Pei-Hsuan Chen, Chia-Ron Yang, C. Teng, 2011, The Journal of nutritional biochemistry.

Nondigestible Oligosaccharides with Anti-obesity Effects.

Pei-Hsuan Chen, Jiao Guo, Z. Su, 2019, Journal of agricultural and food chemistry.

Mutual interaction between endoplasmic reticulum and mitochondria in nonalcoholic fatty liver disease

Pei-Hsuan Chen, Jiao Guo, Z. Su, 2020, Lipids in Health and Disease.

A peripheral immune signature of responsiveness to PD-1 blockade in patients with classical Hodgkin lymphoma

D. Neuberg, M. Shipp, X. Liu, 2020, Nature Medicine.

Genomic Analyses of PMBL Reveal New Drivers and Mechanisms of Sensitivity to PD-1 Blockade.

Andrew J. Dunford, C. Stewart, M. Shipp, 2019, Blood.

The microenvironmental niche in classic Hodgkin lymphoma is enriched for CTLA-4- positive T-cells that are PD-1-negative.

M. Shipp, S. Rodig, P. Armand, 2019, Blood.

Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer

Michael Peyton, John D. Minna, Donna M. Muzny, 2018, Cell.

NRF2 regulates serine biosynthesis in non-small cell lung cancer

R. Deberardinis, J. Minna, I. Wistuba, 2015, Nature Genetics.

Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism

Kathryn A. O’Donnell, R. Deberardinis, Prashant Mishra, 2018, Cell reports.

Metabolic diversity in human non-small cell lung cancer

B. Faubert, R. Deberardinis, J. Minna, 2014, bioRxiv.

Inactivation of Fbxw7 impairs dsRNA sensing and confers resistance to PD-1 blockade.

Charles H. Yoon, S. Carter, G. Freeman, 2020, Cancer discovery.

NRF 2 regulates serine biosynthesis in non-small cell lung cancer

R. Deberardinis, J. Minna, L. Cantley, 2016 .

Erratum: NRF2 regulates serine biosynthesis in non–small cell lung cancer

R. Deberardinis, J. Minna, I. Wistuba, 2016, Nature Genetics.

Circulating Th17 T cells at treatment onset predict autoimmune toxicity of PI3Kδ inhibitors

S. Tyekucheva, S. Rodig, S. Fernandes, 2023, Blood Cancer Journal.

Spatial Signatures Identify Immune Escape via PD-1 as a Defining Feature of T-cell/Histiocyte-rich Large B-cell Lymphoma.

A. LaCasce, D. Neuberg, M. Shipp, 2020, Blood.

Pembrolizumab in Relapsed or Refractory Primary Mediastinal Large B-Cell Lymphoma

G. Salles, D. Neuberg, M. Shipp, 2019, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Lactobacillus plantarum reverse diabetes-induced Fmo3 and ICAM expression in mice through enteric dysbiosis-related c-Jun NH2-terminal kinase pathways

Ching-mei Hsu, Pei-Hsuan Chen, Lee-Wei Chen, 2018, PloS one.

Mitochondrial morphology controls fatty acid utilization by changing CPT1 sensitivity to malonyl‐CoA

Ajit S. Divakaruni, Siyouneh Baghdasarian, N. Danial, 2023, The EMBO journal.

Lactobacillus salivarius reverse diabetes-induced intestinal defense impairment in mice through non-defensin protein.

Ching-mei Hsu, Pei-Hsuan Chen, Lee-Wei Chen, 2016, The Journal of nutritional biochemistry.

Cancer-Specific Production of N-Acetylaspartate via NAT8L Overexpression in Non–Small Cell Lung Cancer and Its Potential as a Circulating Biomarker

R. Deberardinis, J. Minna, M. White, 2015, Cancer Prevention Research.

LKB1 and KEAP1/NRF2 pathways cooperatively promote metabolic reprogramming with enhanced glutamine dependence in KRAS-mutant lung adenocarcinoma.

R. Deberardinis, Jing Wang, J. Minna, 2019, Cancer research.

Mutual interaction between endoplasmic reticulum and mitochondria in nonalcoholic fatty liver disease

Pei-Hsuan Chen, Jiao Guo, Z. Su, 2020, Lipids in Health and Disease.

Inhibiting adipose tissue M1 cytokine expression decreases DPP4 activity and insulin resistance in a type 2 diabetes mellitus mouse model

Pei-Hsuan Chen, Lee-Wei Chen, J. Yen, 2021, PloS one.

Cancer-specific production of N-acetylaspartate via NAT 8 L overexpression in non-small cell lung cancer and its potential as a circulating biomarker Running Title : Cancer-specific production of N-acetylaspartate in NSCLC

R. Deberardinis, J. Minna, M. White, 2015 .

Aryl hydrocarbon receptor ligands enhance lung immunity through intestinal IKKβ pathways

Pei-Hsuan Chen, Lee-Wei Chen, Tzyy-Bin Tsay, 2019, Journal of Translational Medicine.

Pembrolizumab in Patients with Relapsed or Refractory Primary Mediastinal Large B-Cell Lymphoma (PMBCL): Data from the Keynote-013 and Keynote-170 Studies

G. Salles, D. Neuberg, M. Shipp, 2018, Blood.

Lactobacillus salivarius reverse antibiotic-induced lung defense impairment in a ventilator model

Pei-Hsuan Chen, Lee-Wei Chen, Ming-Chieh Yang, 2018, Journal of Translational Medicine.

Title: Clinical and Biological Evaluation of the Novel CD30/CD16A Tetravalent Bispecific Antibody (AFM13) in Relapsed or Refractory CD30-Positive Lymphoma with Cutaneous Presentation: A Biomarker Phase Ib/IIa Study (NCT03192202)

S. Rodig, Pei-Hsuan Chen, G. Vlad, 2020, Blood.

IKappaB-kinase/nuclear factor-kappaB signaling prevents thermal injury-induced gut damage by inhibiting c-Jun NH2-terminal kinase activation.

M. Karin, Ching-mei Hsu, Pei-Hsuan Chen, 2007, Critical Care Medicine.

Blocking TNF-α enhances Pseudomonas aeruginosa-induced mortality in burn mice through induction of IL-1β.

Ching-mei Hsu, Pei-Hsuan Chen, Lee-Wei Chen, 2013, Cytokine.

Peritonitis-induced peroxynitrite and lung damage depends on c-Jun NH2-terminal kinase signaling of hematopoietic cells

Ching-mei Hsu, Pei-Hsuan Chen, Lee-Wei Chen, 2010, Critical care medicine.

TLR LIGAND DECREASES MESENTERIC ISCHEMIA AND REPERFUSION INJURY-INDUCED GUT DAMAGE THROUGH TNF-&agr; SIGNALING

Ching-mei Hsu, Pei-Hsuan Chen, Lee-Wei Chen, 2008, Shock.

Metabolic Diversity in Human Non-Small Cell Lung Cancer Cells

B. Faubert, R. Deberardinis, J. Minna, 2015, bioRxiv.

Monocyte chemoattractant protein-1-supplemented plasma enhances adiponectin and adipogenesis-related gene expression.

Pei-Hsuan Chen, Lee-Wei Chen, Tzyy-Bin Tsay, 2022, Stem cells and development.

Adipose-derived stromal cells reverse insulin resistance through inhibition of M1 expression in a type 2 diabetes mellitus mouse model

Pei-Hsuan Chen, Lee-Wei Chen, J. Yen, 2022, Stem Cell Research & Therapy.