I. Wierstra

发表

The c-myc promoter: still MysterY and challenge.

I. Wierstra, J. Alves, Inken Wierstra, 2008, Advances in cancer research.

FOXM1, a typical proliferation-associated transcription factor

I. Wierstra, J. Alves, Inken Wierstra, 2007, Biological chemistry.

FOXM1 (Forkhead box M1) in tumorigenesis: overexpression in human cancer, implication in tumorigenesis, oncogenic functions, tumor-suppressive properties, and target of anticancer therapy.

I. Wierstra, Inken Wierstra, 2013, Advances in cancer research.

FOXM1c is activated by cyclin E/Cdk2, cyclin A/Cdk2, and cyclin A/Cdk1, but repressed by GSK-3alpha.

I. Wierstra, J. Alves, Inken Wierstra, 2006, Biochemical and biophysical research communications.

Differential effects of methyl jasmonate on the expression of the early light-inducible proteins and other light-regulated genes in barley.

I. Wierstra, K. Kloppstech, Inken Wierstra, 2000, Plant physiology.

Cyclin D1/Cdk4 increases the transcriptional activity of FOXM1c without phosphorylating FOXM1c.

I. Wierstra, 2013, Biochemical and biophysical research communications.

The transcription factor FOXM1 (Forkhead box M1): proliferation-specific expression, transcription factor function, target genes, mouse models, and normal biological roles.

I. Wierstra, Inken Wierstra, 2013, Advances in cancer research.

FOXM1c transactivates the human c‐myc promoter directly via the two TATA boxes P1 and P2

I. Wierstra, J. Alves, Inken Wierstra, 2006, The FEBS journal.

The transcription factor FOXM1c binds to and transactivates the promoter of the tumor suppressor gene E-cadherin

I. Wierstra, Inken Wierstra, 2011, Cell cycle.

Sp1: emerging roles--beyond constitutive activation of TATA-less housekeeping genes.

I. Wierstra, Inken Wierstra, 2008, Biochemical and biophysical research communications.

The transcription factor FOXM1c is activated by protein kinase CK2, protein kinase A (PKA), c-Src and Raf-1.

I. Wierstra, Inken Wierstra, 2011, Biochemical and biophysical research communications.

Transcription factor FOXM1c is repressed by RB and activated by cyclin D1/Cdk4

I. Wierstra, J. Alves, Inken Wierstra, 2006, Biological chemistry.

Despite its strong transactivation domain, transcription factor FOXM1c is kept almost inactive by two different inhibitory domains

I. Wierstra, J. Alves, Inken Wierstra, 2006, Biological chemistry.

Cyclin E/Cdk2, P/CAF, and E1A regulate the transactivation of the c-myc promoter by FOXM1.

I. Wierstra, J. Alves, Inken Wierstra, 2008, Biochemical and biophysical research communications.

The central domain of transcription factor FOXM1c directly interacts with itself in vivo and switches from an essential to an inhibitory domain depending on the FOXM1c binding site

I. Wierstra, J. Alves, 2007, Biological chemistry.