Yingjie Chen

发表

Disruption of Sarcolemmal ATP-Sensitive Potassium Channel Activity Impairs the Cardiac Response to Systolic Overload

Xinli Hu, T. Flagg, C. Nichols, 2008, Circulation research.

Metformin Protects Against Systolic Overload–Induced Heart Failure Independent of AMP-Activated Protein Kinase &agr;2

B. Viollet, Xinli Hu, Huan Wang, 2014, Hypertension.

NADPH oxidase contributes to coronary endothelial dysfunction in the failing heart.

Xin Xu, R. Bache, Yingjie Chen, 2009, American journal of physiology. Heart and circulatory physiology.

AMP Activated Protein Kinase-&agr;2 Regulates Expression of Estrogen-Related Receptor-&agr;, a Metabolic Transcription Factor Related to Heart Failure Development

B. Viollet, Jennifer L Hall, Xinli Hu, 2011, Hypertension.

Reduced expression of mitochondrial electron transport chain proteins from hibernating hearts relative to ischemic preconditioned hearts in the second window of protection.

Jianyi(Jay) Zhang, Yingjie Chen, W. Sluiter, 2013, Journal of molecular and cellular cardiology.

Genetic and Pharmacologic Inhibition of the Chemokine Receptor CXCR2 Prevents Experimental Hypertension and Vascular Dysfunction

J. Fassett, Yingjie Chen, Xin Zhou, 2016, Circulation.

Asymmetric dimethylarginine (ADMA) as an important risk factor for the increased cardiovascular diseases and heart failure in chronic kidney disease.

Xin Xu, Yingjie Chen, Xiaohong Liu, 2018, Nitric oxide : biology and chemistry.

Dimethylarginine Dimethylaminohydrolase 1 Modulates Endothelial Cell Growth Through Nitric Oxide and Akt

Xinli Hu, Xin Xu, R. Bache, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Xanthine oxidase inhibition with febuxostat attenuates systolic overload-induced left ventricular hypertrophy and dysfunction in mice.

Lin Zhao, Xinli Hu, Xin Xu, 2008, Journal of cardiac failure.

AMP Activated Protein Kinase-α2 Deficiency Exacerbates Pressure-Overload–Induced Left Ventricular Hypertrophy and Dysfunction in Mice

B. Viollet, Xinli Hu, D. Bernlohr, 2008, Hypertension.

Cardiomyocyte dimethylarginine dimethylaminohydrolase-1 (DDAH1) plays an important role in attenuating ventricular hypertrophy and dysfunction

Xinli Hu, Xin Xu, J. Fassett, 2017, Basic Research in Cardiology.

Repetitive ischemia increases myocardial dimethylarginine dimethylaminohydrolase 1 expression

Xinli Hu, Xin Xu, J. Fassett, 2017, Vascular medicine.

DDAH1 Deficiency Attenuates Endothelial Cell Cycle Progression and Angiogenesis

Xinli Hu, Huan Wang, Xin Xu, 2013, PloS one.

Dimethylarginine dimethylaminohydrolase and endothelial dysfunction in failing hearts.

Xin Xu, R. Bache, Yingjie Chen, 2005, American journal of physiology. Heart and circulatory physiology.

Adenosine kinase attenuates cardiomyocyte microtubule stabilization and protects against pressure overload-induced hypertrophy and LV dysfunction.

B. Mayer, Xin Xu, J. Fassett, 2019, Journal of molecular and cellular cardiology.

Extracellular superoxide dismutase protects the heart against oxidative stress and hypertrophy after myocardial infarction.

Xinli Hu, T. Oury, Xin Xu, 2008, Free radical biology & medicine.

AMP-Activated Protein Kinase α1 Protects Against Diet-Induced Insulin Resistance and Obesity

B. Viollet, Chunxiang Zhang, Chuhong Zhu, 2012, Diabetes.

Increased superoxide production causes coronary endothelial dysfunction and depressed oxygen consumption in the failing heart.

R. Bache, Yingjie Chen, J. Traverse, 2005, American journal of physiology. Heart and circulatory physiology.

Inhibition of NO production increases myocardial blood flow and oxygen consumption in congestive heart failure.

R. Bache, Yingjie Chen, J. Traverse, 2002, American journal of physiology. Heart and circulatory physiology.

Effect of PDE5 inhibition on coronary hemodynamics in pacing-induced heart failure.

R. Bache, Yingjie Chen, J. Traverse, 2003, American journal of physiology. Heart and circulatory physiology.

Effect of PDE 5 inhibition on coronary hemodynamics in pacing-induced heart failure

R. Bache, Yingjie Chen, J. Traverse, 2003 .

Inducible Nitric Oxide Synthase Deficiency Protects the Heart From Systolic Overload–Induced Ventricular Hypertrophy and Congestive Heart Failure

Xinli Hu, Xin Xu, Yingjie Chen, 2007, Circulation research.

Acute Effects of Febuxostat, a Nonpurine Selective Inhibitor of Xanthine Oxidase, in Pacing Induced Heart Failure

Jianyi(Jay) Zhang, R. Bache, Yingjie Chen, 2006, Journal of cardiovascular pharmacology.

Differential regulation of membrane guanylyl cyclases in congestive heart failure: natriuretic peptide receptor (NPR)-B, Not NPR-A, is the predominant natriuretic peptide receptor in the failing heart.

Xin Xu, Yingjie Chen, D. Dickey, 2007, Endocrinology.

Adenosine: a modulator of the cardiac response to stress.

R. Bache, Yingjie Chen, 2003, Circulation research.

Pharmacological and Genetic Inhibition of PD-1 Demonstrate an Important Role of PD-1 in Ischemia-Induced Skeletal Muscle Inflammation, Oxidative Stress, and Angiogenesis

Yingjie Chen, Xiaoguang Liu, Peijie Chen, 2021, Frontiers in Immunology.

Isolevuglandin scavenger attenuates pressure overload-induced cardiac oxidative stress, cardiac hypertrophy, heart failure and lung remodeling.

E. K. Weir, Yingjie Chen, R. Mernaugh, 2019, Free radical biology & medicine.

Role of bone marrow-derived CD11c+ dendritic cells in systolic overload-induced left ventricular inflammation, fibrosis and hypertrophy

Huan Wang, Xin Xu, J. Fassett, 2017, Basic Research in Cardiology.

Kidney injury, arterial hypertension and left ventricular hypertrophy in rats with loss of function mutation of SOD3.

Xin Xu, Yingjie Chen, A. Geurts, 2020, Free radical biology & medicine.

Extracellular Superoxide Dismutase Deficiency Exacerbates Pressure Overload–Induced Left Ventricular Hypertrophy and Dysfunction

Xinli Hu, T. Oury, Xin Xu, 2008, Hypertension.

CD28/B7 Deficiency Attenuates Systolic Overload-Induced Congestive Heart Failure, Myocardial and Pulmonary Inflammation, and Activated T Cell Accumulation in the Heart and Lungs

Xin Xu, J. Fassett, R. Bache, 2016, Hypertension.

Nitric Oxide Modulates Myocardial Oxygen Consumption in the Failing Heart

R. Bache, Yingjie Chen, J. Traverse, 2002, Circulation.

Dimethylarginine dimethylaminohydrolase 1 deficiency aggravates monocrotaline-induced pulmonary oxidative stress, pulmonary arterial hypertension and right heart failure in rats.

E. K. Weir, Hailing Li, Yingjie Chen, 2019, International journal of cardiology.

ET-A Receptor Activity Restrains Coronary Blood Flow in the Failing Heart

R. Bache, Yingjie Chen, J. Traverse, 2004, Journal of cardiovascular pharmacology.

Profound Increase of Lung Airway Resistance in Heart Failure: a Potential Important Contributor for Dyspnea

E. K. Weir, Xin Xu, Yingjie Chen, 2019, Journal of Cardiovascular Translational Research.

Inducible nitric oxide synthase inhibits oxygen consumption in collateral-dependent myocardium.

Xin Xu, R. Bache, Yingjie Chen, 2014, American journal of physiology. Heart and circulatory physiology.

Ecto-5′-Nucleotidase Deficiency Exacerbates Pressure-Overload–Induced Left Ventricular Hypertrophy and Dysfunction

Xinli Hu, Xin Xu, J. Fassett, 2008, Hypertension.

Adenosine A3 Receptor Deficiency Exerts Unanticipated Protective Effects on the Pressure-Overloaded Left Ventricle

Xinli Hu, Xin Xu, J. Fassett, 2008, Circulation.

Left Ventricular Failure Produces Profound Lung Remodeling and Pulmonary Hypertension in Mice: Heart Failure Causes Severe Lung Disease

Xinli Hu, E. K. Weir, Huan Wang, 2012, Hypertension.

Exacerbated Pulmonary Arterial Hypertension and Right Ventricular Hypertrophy in Animals With Loss of Function of Extracellular Superoxide Dismutase

Xinli Hu, E. K. Weir, E. Ostertag, 2011, Hypertension.

Oxidative Stress Regulates Left Ventricular PDE5 Expression in the Failing Heart

Xinli Hu, Xin Xu, J. Fassett, 2010, Circulation.

Regulation of DDAH1 as a Potential Therapeutic Target for Treating Cardiovascular Diseases

J. Fassett, Yingjie Chen, Yidong Wei, 2013, Evidence-based complementary and alternative medicine : eCAM.

Renal hyporesponsiveness to atrial natriuretic peptide in congestive heart failure results from reduced atrial natriuretic peptide receptor concentrations.

Xin Xu, Yingjie Chen, D. Dickey, 2007, American journal of physiology. Renal physiology.

S-nitrosylation of PDE5 increases its ubiquitin-proteasomal degradation.

Yingjie Chen, Zhiyu Xu, Zhongbing Lu, 2015, Free radical biology & medicine.

Dissecting VEGF-induced acute versus chronic vascular hyperpermeability: Essential roles of dimethylarginine dimethylaminohydrolase-1

Luke H. Hoeppner, Tanmay Kulkarni, Alex Y Tam, 2020, iScience.

Systolic overload-induced pulmonary inflammation, fibrosis, oxidative stress and heart failure progression through interleukin-1β.

Michael E. Hall, Yingjie Chen, M. Hall, 2020, Journal of molecular and cellular cardiology.

Loss of the Eukaryotic Initiation Factor 2&agr; Kinase General Control Nonderepressible 2 Protects Mice From Pressure Overload–Induced Congestive Heart Failure Without Affecting Ventricular Hypertrophy

Xinli Hu, Huan Wang, Xin Xu, 2014, Hypertension.

PGC-1 alpha regulates expression of myocardial mitochondrial antioxidants and myocardial oxidative stress after chronic systolic overload.

Xinli Hu, Xin Xu, Yi-min Huang, 2010, Antioxidants & redox signaling.

Integrative Physiology and Experimental Medicine Dimethylarginine Dimethylaminohydrolase-1 Is the Critical Enzyme for Degrading the Cardiovascular Risk Factor Asymmetrical Dimethylarginine

Xinli Hu, Xin Xu, J. Fassett, 2011 .

Vascular Endothelial-Specific Dimethylarginine Dimethylaminohydrolase-1–Deficient Mice Reveal That Vascular Endothelium Plays an Important Role in Removing Asymmetric Dimethylarginine

Xinli Hu, Xin Xu, Yingjie Chen, 2009, Circulation.

Effect of K+ATP Channel and Adenosine Receptor Blockade During Rest and Exercise in Congestive Heart Failure

R. Bache, Yingjie Chen, J. Traverse, 2007, Circulation research.

Effect of K (cid:1) ATP Channel and Adenosine Receptor Blockade During Rest and Exercise in Congestive Heart Failure

R. Bache, Yingjie Chen, J. Traverse, 2007 .

Endoplasmic Reticulum Stress Sensor Protein Kinase R–Like Endoplasmic Reticulum Kinase (PERK) Protects Against Pressure Overload–Induced Heart Failure and Lung Remodeling

Xinli Hu, Huan Wang, Xin Xu, 2014, Hypertension.

Overexpression of alanine-glyoxylate aminotransferase 2 protects from asymmetric dimethylarginine-induced endothelial dysfunction and aortic remodeling

S. Bornstein, Yingjie Chen, R. Maas, 2021, Scientific Reports.

Inducible Nitric Oxide Synthase Deficiency Protects the Heart From Systolic Overload–Induced Ventricular Hypertrophy and Congestive Heart Failure

Xinli Hu, Xin Xu, Yingjie Chen, 2007, Circulation research.

Adenosine kinase regulation of cardiomyocyte hypertrophy.

Xinli Hu, Xin Xu, J. Fassett, 2011, American journal of physiology. Heart and circulatory physiology.

Increasing Regulatory T Cells With Interleukin-2 and Interleukin-2 Antibody Complexes Attenuates Lung Inflammation and Heart Failure Progression

Huan Wang, Xin Xu, J. Fassett, 2016, Hypertension.

Single-Cell Transcriptome Analysis Decipher New Potential Regulation Mechanism of ACE2 and NPs Signaling Among Heart Failure Patients Infected With SARS-CoV-2

Yingjie Chen, Dachun Xu, Xiaojiang Xu, 2021, Frontiers in Cardiovascular Medicine.

NOX2-induced myocardial fibrosis and diastolic dysfunction: role of the endothelium.

R. Bache, Yingjie Chen, 2014, Journal of the American College of Cardiology.

Microtubule Actin Cross-Linking Factor 1 Regulates Cardiomyocyte Microtubule Distribution and Adaptation to Hemodynamic Overload

Xinli Hu, Huan Wang, Xin Xu, 2013, PloS one.

AMPK&agr;2 deficiency exacerbates long‐term PM2.5 exposure‐induced lung injury and cardiac dysfunction

Yingjie Chen, Ying Huang, Fang Zhang, 2018, Free radical biology & medicine.

Short term Pm2.5 exposure caused a robust lung inflammation, vascular remodeling, and exacerbated transition from left ventricular failure to right ventricular hypertrophy

E. K. Weir, Yingjie Chen, Wenjun Ding, 2019, Redox biology.

Effect of asymmetric dimethylarginine (ADMA) on heart failure development.

J. Fassett, Yingjie Chen, Yawei Xu, 2016, Nitric oxide : biology and chemistry.

Double-Stranded RNA–Dependent Protein Kinase Deficiency Protects the Heart From Systolic Overload-Induced Congestive Heart Failure

Xinli Hu, Huan Wang, Xin Xu, 2014, Circulation.

Adenosine regulation of microtubule dynamics in cardiac hypertrophy.

Xinli Hu, Xin Xu, J. Fassett, 2009, American journal of physiology. Heart and circulatory physiology.

Microtubule Actin Cross-Linking Factor 1 Regulates Cardiomyocyte Microtubule Distribution and Adaptation to Hemodynamic Overload

Xinli Hu, Huan Wang, Xin Xu, 2013, American journal of physiology. Heart and circulatory physiology.

Xinqiang Han , following left ventricular assist device support Alterations of gene expression in failing myocardium

L. Miller, R. Bache, Yingjie Chen, 2003 .

Effect of asymmetric dimethylarginine (ADMA) on heart failure development.

J. Fassett, Yingjie Chen, Yawei Xu, 2016, Nitric oxide : biology and chemistry.

Left Ventricular Failure Produces Profound Lung Remodeling and Pulmonary Hypertension in Mice: Heart Failure Causes Severe Lung Disease

Xinli Hu, Huan Wang, Xin Xu, 2012, Hypertension.

Extracellular Superoxide Dismutase Deficiency Exacerbates Pressure Overload–Induced Left Ventricular Hypertrophy and Dysfunction

Xinli Hu, T. Oury, Xin Xu, 2008, Hypertension.

Effect of sildenafil on coronary active and reactive hyperemia.

R. Bache, Yingjie Chen, J. Traverse, 2000, American journal of physiology. Heart and circulatory physiology.

AMP-Activated Protein Kinase α1 Protects Against Diet-Induced Insulin Resistance and Obesity

B. Viollet, Chunxiang Zhang, Chuhong Zhu, 2012, Diabetes.

Increased extravascular forces limit endothelium-dependent and -independent coronary vasodilation in congestive heart failure.

R. Bache, Yingjie Chen, J. Traverse, 2001, Cardiovascular research.