Won-Tak Choi

发表

Neuronal Apoptotic Signaling Pathways Probed and Intervened by Synthetically and Modularly Modified (SMM) Chemokines*

M. Kaul, S. Lipton, Won-Tak Choi, 2007, Journal of Biological Chemistry.

Targeting chemokine receptor CXCR4 for treatment of HIV-1 infection, tumor progression, and metastasis.

Won-Tak Choi, J. An, Yan Xu, 2014, Current topics in medicinal chemistry.

CCR5 Mutations Distinguish N-Terminal Modifications of RANTES (CCL5) with Agonist versus Antagonist Activity

R. Offord, Won-Tak Choi, D. Mosier, 2012, Journal of Virology.

SMM-chemokines: a class of unnatural synthetic molecules as chemical probes of chemokine receptor biology and leads for therapeutic development.

D. Richman, J. Sodroski, James J Pesavento, 2006, Chemistry & biology.

Role of CXCR4 internalization in the anti-HIV activity of stromal cell-derived factor-1α probed by a novel synthetically and modularly modified-chemokine analog

J. Sodroski, Won-Tak Choi, Santosh Kumar, 2011, Experimental biology and medicine.

Critical role in CXCR4 signaling and internalization of the polypeptide main chain in the amino terminus of SDF-1α probed by novel N-methylated synthetically and modularly modified chemokine analogues.

Won-Tak Choi, C. Dong, J. An, 2012, Biochemistry.

Distinct Functional Sites for Human Immunodeficiency Virus Type 1 and Stromal Cell-Derived Factor 1α on CXCR4 Transmembrane Helical Domains

Won-Tak Choi, Dongxiang Liu, J. Sodroski, 2005, Journal of Virology.

Biology and clinical relevance of chemokines and chemokine receptors CXCR4 and CCR5 in human diseases

Won-Tak Choi, Won-Tak Choi, J. An, 2011, Experimental biology and medicine.

Liver epithelial focal adhesion kinase modulates fibrogenesis and hedgehog signaling

Won-Tak Choi, Yun Weng, Tammy T. Chang, 2020, JCI insight.

Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4).

Won-Tak Choi, Won-Tak Choi, J. An, 2012, Journal of medicinal chemistry.

Crystal Structure and Structural Mechanism of a Novel Anti-Human Immunodeficiency Virus and d-Amino Acid-Containing Chemokine

Ying Li, Won-Tak Choi, Rong Cao, 2007, Journal of Virology.

A novel synthetic bivalent ligand to probe chemokine receptor CXCR4 dimerization and inhibit HIV-1 entry.

J. Sodroski, Won-Tak Choi, C. Dong, 2012, Biochemistry.

Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4).

Won-Tak Choi, J. An, Ziwei Huang, 2011, Journal of medicinal chemistry.

Unique Ligand Binding Sites on CXCR4 Probed by a Chemical Biology Approach: Implications for the Design of Selective Human Immunodeficiency Virus Type 1 Inhibitors

Won-Tak Choi, Dongxiang Liu, Navid Madani, 2005, Journal of Virology.

Basic and Translational Research of Chemokine Ligands and Receptors and Development of Novel Therapeutics

D. Richman, J. Sodroski, Won-Tak Choi, 2006 .

Different stereochemical requirements for CXCR4 binding and signaling functions as revealed by an anti-HIV, D-amino acid-containing SMM-chemokine ligand.

J. Sodroski, Won-Tak Choi, Santosh Kumar, 2005, Journal of medicinal chemistry.