Y. Izumi

发表

Pravastatin induces rat aortic endothelial cell proliferation and migration via activation of PI3K/Akt/mTOR/p70 S6 kinase signaling.

T. Nakao, H. Iwao, M. Shiota, 2007, Journal of pharmacological sciences.

Effects of liposome clodronate on renal leukocyte populations and renal fibrosis in murine obstructive nephropathy.

T. Nakao, K. Miura, T. Yukimura, 2009, Journal of pharmacological sciences.

Hydrogen gas attenuates embryonic gene expression and prevents left ventricular remodeling induced by intermittent hypoxia in cardiomyopathic hamsters.

Y. Izumi, A. Sakamoto, M. Yoshiyama, 2014, American journal of physiology. Heart and circulatory physiology.

Beneficial effects of combination of ACE inhibitor and angiotensin II type 1 receptor blocker on cardiac remodeling in rat myocardial infarction.

Shokei Kim, H. Iwao, Y. Izumi, 2003, Cardiovascular research.

Differences in time course of myocardial mRNA expression in non-infarcted myocardium after myocardial infarction

Shokei Kim, H. Iwao, Y. Izumi, 2000, Basic Research in Cardiology.

The antifibrotic agent pirfenidone inhibits angiotensin II-induced cardiac hypertrophy in mice

H. Iwao, M. Shiota, Y. Izumi, 2012, Hypertension Research.

Gene expression profile in experimental mesangial proliferative glomerulonephritis.

G. Tsujimoto, T. Yukimura, H. Iwao, 2004, Journal of pharmacological sciences.

Percutaneous carbon dioxide treatment using a gas mist generator enhances the collateral blood flow in the ischemic hindlimb.

H. Wanibuchi, K. Miura, H. Iwao, 2015, Journal of atherosclerosis and thrombosis.

Important Role of Apoptosis Signal-Regulating Kinase 1 in Ischemia-Induced Angiogenesis

T. Murohara, T. Yukimura, H. Iwao, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Role of Apoptosis Signal-Regulating Kinase 1 in Ischemia-Induced

T. Murohara, T. Yukimura, Y. Izumi, 2005 .

Apoptosis Signal-Regulating Kinase 1 Plays a Pivotal Role in Angiotensin II–Induced Cardiac Hypertrophy and Remodeling

Shokei Kim, H. Iwao, H. Ichijo, 2003, Circulation research.

Effect of Continuous Ang II Infusion on Cardiac Superoxide Production and ASK 1 , MAPK Activation , and Cardiac Hypertrophy in Wild-Type Mice

Shokei Kim, H. Iwao, H. Ichijo, 2003 .

Angiotensin blockade inhibits activation of mitogen-activated protein kinases in rat balloon-injured artery.

Shokei Kim, A. Hamaguchi, K. Miura, 1998, Circulation.

Percutaneous carbon dioxide mist treatment has protective effects in experimental myocardial infarction.

K. Miura, H. Iwao, M. Shiota, 2015, Journal of pharmacological sciences.

Augmented O-GlcNAcylation attenuates intermittent hypoxia-induced cardiac remodeling through the suppression of NFAT and NF-κB activities in mice

Y. Izumi, M. Yoshiyama, T. Nakagawa, 2019, Hypertension Research.

Involvement of Apoptosis Signal-Regulating Kinase-1 on Angiotensin II-Induced Monocyte Chemoattractant Protein-1 Expression

Shokei Kim, H. Iwao, H. Ichijo, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Passive Exercise Using Whole-Body Periodic Acceleration Enhances Blood Supply to Ischemic Hindlimb

M. Fujita, O. Yasuda, Y. Izumi, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Angiotensin converting enzyme inhibitor prevents left ventricular remodelling after myocardial infarction in angiotensin II type 1 receptor knockout mice

Shokei Kim, H. Iwao, Y. Izumi, 2005, Heart.

Beneficial effect of candesartan on rat diastolic heart failure.

T. Yukimura, H. Iwao, M. Shiota, 2005, Journal of pharmacological sciences.

Angiotensin blockade inhibits osteopontin expression in non-infarcted myocardium after myocardial infarction.

H. Iwao, Y. Izumi, M. Yoshiyama, 2005, Journal of pharmacological sciences.

[Pleiotropic effects of statins on endothelium and signaling mechanisms].

T. Nakao, H. Iwao, M. Shiota, 2006, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

Effects of metoprolol on epinephrine-induced takotsubo-like left ventricular dysfunction in non-human primates

T. Nakao, K. Miura, H. Iwao, 2009, Hypertension Research.

Effects of intravenous atrial natriuretic peptide and nitroglycerin on coronary vasodilation and flow velocity determined using 3 T magnetic resonance imaging in patients with nonischemic heart failure

Y. Izumi, K. Shimada, M. Yoshiyama, 2013, Heart and Vessels.

Therapeutic potential of vasopressin-receptor antagonists in heart failure.

K. Miura, H. Iwao, Y. Izumi, 2014, Journal of pharmacological sciences.

Heat Shock Cognate Protein 70 Is Essential for Akt Signaling in Endothelial Function

T. Nakao, Y. Funae, K. Miura, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Myeloid HIF-1 attenuates the progression of renal fibrosis in murine obstructive nephropathy.

K. Miura, M. Shiota, Y. Izumi, 2015, Journal of pharmacological sciences.

Tolvaptan attenuates left ventricular fibrosis after acute myocardial infarction in rats.

K. Miura, H. Iwao, H. Fujiki, 2013, Journal of pharmacological sciences.

Pravastatin accelerates ischemia-induced angiogenesis through AMP-activated protein kinase

T. Nakao, K. Miura, H. Iwao, 2009, Hypertension Research.

Effects of Combination of ACE Inhibitor and Angiotensin Receptor Blocker on Cardiac Remodeling, Cardiac Function, and Survival in Rat Heart Failure

Shokei Kim, H. Iwao, Y. Izumi, 2001, Circulation.

Cardiovascular effects of combination of perindopril, candesartan, and amlodipine in hypertensive rats.

Shokei Kim, H. Iwao, Y. Izumi, 2000, Hypertension.

Tolvaptan Improves Left Ventricular Dysfunction after Myocardial Infarction in Rats

H. Iwao, H. Fujiki, M. Shiota, 2012, Circulation. Heart failure.

The Long-Acting Ca 2+ -Channel Blocker Azelnidipine Prevents Left Ventricular Remodeling After Myocardial Infarction

H. Iwao, Y. Izumi, M. Yoshiyama, 2007 .

Effects of cellular cardiomyoplasty on ventricular remodeling assessed by Doppler echocardiography and topographic immunohistochemistry.

Y. Izumi, Y. Kitaura, M. Yoshiyama, 2004, Circulation journal : official journal of the Japanese Circulation Society.

Effects of eplerenone on transcriptional factors and mRNA expression related to cardiac remodelling after myocardial infarction

Shokei Kim, H. Iwao, Y. Izumi, 2005, Heart.

The Effect of the Intake of Rice Crackers Containing Indigestible Dextrin on Postprandial Blood Glucose Levels in Healthy Adults

Y. Izumi, K. Shiraishi, S. Yamasaki, 2006 .

Additive beneficial effects of the combination of a calcium channel blocker and an angiotensin blocker on a hypertensive rat-heart failure model.

H. Iwao, Y. Izumi, Y. Izumiya, 2004, Hypertension research : official journal of the Japanese Society of Hypertension.

Four cases of investigational therapy with interleukin-11 against acute myocardial infarction

Y. Fujio, Makiko Maeda, Y. Izumi, 2016, Heart and Vessels.

Differential activation of cardiac c-jun amino-terminal kinase and extracellular signal-regulated kinase in angiotensin II-mediated hypertension.

Shokei Kim, H. Iwao, Y. Izumi, 1998, Circulation research.

Rivaroxaban Attenuates Right Ventricular Remodeling in Rats with Pulmonary Arterial Hypertension.

Y. Izumi, M. Yoshiyama, T. Nakano, 2021, Biological & pharmaceutical bulletin.

fibrinolytic, and coagulation factors Periodic acceleration: effects on vasoactive,

M. Sackner, M. Fujita, O. Yasuda, 2015 .

Pravastatin-induced proangiogenic effects depend upon extracellular FGF-2

T. Nakao, Y. Funae, K. Miura, 2012, Journal of cellular and molecular medicine.

Dominant-negative c-Jun inhibits rat cardiac hypertrophy induced by angiotensin II and hypertension

H. Iwao, Y. Izumi, Y. Izumiya, 2006, Gene Therapy.

Contribution of extracellular signal-regulated kinase to angiotensin II-induced transforming growth factor-beta1 expression in vascular smooth muscle cells.

Shokei Kim, A. Hamaguchi, H. Iwao, 1999, Hypertension.

A dipeptidyl peptidase-4 (DPP-4) inhibitor, linagliptin, attenuates cardiac dysfunction after myocardial infarction independently of DPP-4.

K. Miura, H. Iwao, M. Shiota, 2019, Journal of pharmacological sciences.

Safety Assessment of Electronic Cigarettes in Smokers

T. Nakao, K. Miura, Y. Izumi, 2011 .

Chronic activation of glomerular mitogen-activated protein kinases in Dahl salt-sensitive rats.

Shokei Kim, A. Hamaguchi, H. Iwao, 2000, Journal of the American Society of Nephrology : JASN.

Role of c-Jun NH2-terminal kinase in G-protein-coupled receptor agonist-induced cardiac plasminogen activator inhibitor-1 expression.

Shokei Kim, H. Iwao, H. Ichijo, 2005, Journal of molecular and cellular cardiology.

Extracellular signal-regulated kinase and c-Jun NH2-terminal kinase activities are continuously and differentially increased in aorta of hypertensive rats.

Shokei Kim, K. Miura, H. Iwao, 1997, Biochemical and biophysical research communications.

Noninvasive metabolic syndrome model using an extremely small minipig, the microminipig.

K. Miura, H. Iwao, M. Shiota, 2014, Journal of pharmacological sciences.

Novel device that produces carbon dioxide mist for myocardial infarction treatment in rats.

H. Iwao, M. Shiota, Y. Izumi, 2012, Circulation journal : official journal of the Japanese Circulation Society.

Red ginseng inhibits scratching behavior associated with atopic dermatitis in experimental animal models.

T. Nakao, K. Miura, H. Iwao, 2012, Journal of pharmacological sciences.

Red ginseng extracts attenuate skin inflammation in atopic dermatitis through p70 ribosomal protein S6 kinase activation.

K. Miura, H. Iwao, Y. Izumi, 2017, Journal of pharmacological sciences.

Critical Role of Angiotensin II in Excess Salt-Induced Brain Oxidative Stress of Stroke-Prone Spontaneously Hypertensive Rats

H. Wanibuchi, H. Iwao, Y. Izumi, 2005, Stroke.

Important Role of Angiotensin II-Mediated c-Jun NH2-Terminal Kinase Activation in Cardiac Hypertrophy in Hypertensive Rats

Shokei Kim, H. Iwao, Y. Izumi, 2000, Hypertension.

Capillary Degeneration and Right Ventricular Remodeling Due to Hypoxic Stress with Sugen5416.

Y. Izumi, M. Yoshiyama, Y. Ijiri, 2017, Current vascular pharmacology.

Microminipig, a Non-rodent Experimental Animal Optimized for Life Science Research: Preface.

Y. Izumi, A. Sugiyama, Naoki Kaneko, 2011, Journal of pharmacological sciences.

Drug-induced takotsubo cardiomyopathy.

Y. Izumi, 2013, Heart failure clinics.

Microbubble destruction with ultrasound augments neovascularisation by bone marrow cell transplantation in rat hind limb ischaemia

H. Iwao, Y. Izumi, M. Yoshiyama, 2005, Heart.

Cardiac mitogen-activated protein kinase activities are chronically increased in stroke-prone hypertensive rats.

Shokei Kim, H. Iwao, Y. Izumi, 1998, Hypertension.

Protease-Activated Receptor-1 Inhibition by FR171113 Attenuates Cardiac Remodeling Due to Intermittent Hypoxia

Y. Izumi, M. Yoshiyama, Y. Ijiri, 2020 .

Augmented O-GlcNAcylation exacerbates right ventricular dysfunction and remodeling via enhancement of hypertrophy, mitophagy, and fibrosis in mice exposed to long-term intermittent hypoxia

Y. Izumi, M. Yoshiyama, T. Nakagawa, 2022, Hypertension Research.

Gene Transfer of Dominant-Negative Mutants of Extracellular Signal-Regulated Kinase and c-Jun NH2-Terminal Kinase Prevents Neointimal Formation in Balloon-Injured Rat Artery

Y. Kaneda, R. Morishita, Shokei Kim, 2001, Circulation research.

Angiotensin AT1 receptor blockers suppress oxidized low-density lipoprotein-derived formation of foam cells.

H. Iwao, Y. Izumi, Mayuko Osada-Oka, 2012, European journal of pharmacology.

Establishment of a 5-fluorouracil-resistant triple-negative breast cancer cell line.

H. Wanibuchi, K. Miura, H. Iwao, 2013, International journal of oncology.

Establishment of neutralizing rat monoclonal antibodies for fibroblast growth factor-2.

Y. Ohkawa, H. Wanibuchi, K. Miura, 2014, Monoclonal antibodies in immunodiagnosis and immunotherapy.

Increased JNK, AP-1 and NF-κB DNA Binding Activities in Isoproterenol-induced Cardiac Remodeling

Shokei Kim, Y. Izumi, M. Yoshiyama, 1999 .

Involvement of c-Jun NH2 Terminal Kinase and p38MAPK in Rapamycin-Mediated Inhibition of Neointimal Formation in Rat Carotid Arteries

Shokei Kim, H. Iwao, Y. Izumi, 2005, Journal of cardiovascular pharmacology.

Gene Transfer of Dominant-Negative Mutants of Extracellular Signal-Regulated Kinase and c-Jun NH2-Terminal Kinase Prevents Neointimal Formation in Balloon-Injured Rat Artery

Y. Kaneda, R. Morishita, Shokei Kim, 2001, Circulation research.

Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells.

H. Wanibuchi, M. Wei, H. Iwao, 2014, Biochemical and biophysical research communications.

Pharmacogenomics of cardiovascular pharmacology: molecular network analysis in pleiotropic effects of statin -- an experimental elucidation of the pharmacologic action from protein-protein interaction analysis.

T. Nakao, H. Iwao, M. Shiota, 2008, Journal of pharmacological sciences.

Microminipig, a Non-rodent Experimental Animal Optimized for Life Science Research: Novel Atherosclerosis Model Induced by High Fat and Cholesterol Diet.

Y. Izumi, A. Tanimoto, N. Miura, 2011, Journal of pharmacological sciences.

Microminipig, a non-rodent experimental animal optimized for life science research: in vivo proarrhythmia models of drug-induced long QT syndrome: development of chronic atrioventricular block model of microminipig.

H. Yamazaki, Y. Izumi, A. Sugiyama, 2011, Journal of pharmacological sciences.

Novel microminipig model of atherosclerosis by high fat and high cholesterol diet, established in Japan.

Y. Izumi, A. Tanimoto, N. Miura, 2010, In vivo.

Role of JNK, p38, and ERK in Platelet-Derived Growth Factor–Induced Vascular Proliferation, Migration, and Gene Expression

T. Nakao, Shokei Kim, H. Iwao, 2003, Arteriosclerosis, thrombosis, and vascular biology.

IL-6-mediated Th17 differentiation through RORγt is essential for the initiation of experimental autoimmune myocarditis.

I. Komuro, Y. Fujio, H. Nakayama, 2011, Cardiovascular research.

Macrophage-derived exosomes induce inflammatory factors in endothelial cells under hypertensive conditions

K. Miura, H. Iwao, M. Shiota, 2017, Hypertension Research.

Increased JNK, AP-1 and NF-kappa B DNA binding activities in isoproterenol-induced cardiac remodeling.

Y. Izumi, M. Yoshiyama, J. Yoshikawa, 1999, Journal of molecular and cellular cardiology.

Ménage-à-Trois 1 Is Critical for the Transcriptional Function of PPARγ Coactivator 1

C. R. Wilson, R. Pautler, Derrick J. Rossi, 2007 .

Activation of Apoptosis Signal-Regulating Kinase 1 in Injured Artery and Its Critical Role in Neointimal Hyperplasia

Shokei Kim, H. Iwao, H. Ichijo, 2003, Circulation.

Excess Aldosterone under Normal Salt Diet Induces Cardiac Hypertrophy and Infiltration via Oxidative Stress

T. Yukimura, H. Iwao, Y. Izumi, 2005, Hypertension Research.

Effects of aldosterone receptor antagonist and angiotensin II type I receptor blocker on cardiac transcriptional factors and mRNA expression in rats with myocardial infarction.

Shokei Kim, H. Iwao, Y. Izumi, 2004, Circulation journal : official journal of the Japanese Circulation Society.

Beneficial Effects of Combined Blockade of ACE and AT1 Receptor on Intimal Hyperplasia in Balloon-Injured Rat Artery

Shokei Kim, H. Iwao, Y. Izumi, 2002, Arteriosclerosis, thrombosis, and vascular biology.

Angiotensin II and Its Related Peptides

H. Iwao, Y. Izumi, 2006 .

Therapeutical Potential of Microvesicles in Cardiovascular Diseases

Y. Izumi, 2012 .

Vascular Endothelial Growth Factor–Expressing Mesenchymal Stem Cell Transplantation for the Treatment of Acute Myocardial Infarction

K. Ohta, Y. Izumi, Y. Kitaura, 2005, Arteriosclerosis, thrombosis, and vascular biology.

[New model of Takotsubo-like left ventricular dysfunction in cynomolgus monkey].

Y. Izumi, 2010, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

Renal fibrosis in murine obstructive nephropathy is attenuated by depletion of monocyte lineage, not dendritic cells.

K. Miura, M. Shiota, Y. Izumi, 2010, Journal of pharmacological sciences.

Factor Xa inhibition by rivaroxaban attenuates cardiac remodeling due to intermittent hypoxia.

Y. Izumi, M. Yoshiyama, Y. Ijiri, 2018, Journal of pharmacological sciences.

The long-acting Ca2+-channel blocker azelnidipine prevents left ventricular remodeling after myocardial infarction.

H. Iwao, Y. Izumi, M. Yoshiyama, 2007, Journal of Pharmacological Sciences.

Microminipig, a Non-rodent Experimental Animal Optimized for Life Science Research: Preface.

Y. Izumi, A. Sugiyama, Naoki Kaneko, 2011, Journal of pharmacological sciences.

Increased oxidative stress during exercise predicts poor prognosis in patients with acute decompensated heart failure

Y. Izumi, Y. Izumiya, M. Yoshiyama, 2021, ESC heart failure.

In Vivo Activation of Rat Aortic Platelet-Derived Growth Factor and Epidermal Growth Factor Receptors by Angiotensin II and Hypertension

Shokei Kim, H. Iwao, Y. Izumi, 2000, Arteriosclerosis, thrombosis, and vascular biology.

Serum brain-derived neurotrophic factor level and exercise tolerance complement each other in predicting the prognosis of patients with heart failure

Y. Izumi, M. Yoshiyama, A. Hanatani, 2018, Heart and Vessels.

Repeated remote ischemic conditioning attenuates left ventricular remodeling via exosome-mediated intercellular communication on chronic heart failure after myocardial infarction.

H. Iwao, M. Shiota, Y. Izumi, 2015, International journal of cardiology.

Identification of low-abundance proteins in serum via the isolation of HSP72 complexes.

T. Nakao, K. Nakayama, Y. Ohkawa, 2016, Journal of proteomics.

Hsc70 Contributes to Cancer Cell Survival by Preventing Rab1A Degradation under Stress Conditions

Y. Ohkawa, H. Wanibuchi, K. Miura, 2014, PloS one.

Severe prekallikrein deficiency due to a homozygous Trp499Stop nonsense mutation.

T. Nakao, T. Yamane, M. Hino, 2011, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Protection of stromal cell-derived factor 2 by heat shock protein 72 prevents oxaliplatin-induced cell death in oxaliplatin-resistant human gastric cancer cells.

K. Nakayama, K. Miura, H. Iwao, 2016, Cancer letters.

Tolvaptan Improves Left Ventricular Dysfunction after Myocardial Infarction in Rats

H. Iwao, H. Fujiki, M. Shiota, 2012, Circulation. Heart failure.

Heat Shock Cognate Protein 70 Is Essential for Akt Signaling in Endothelial Function

T. Nakao, Y. Funae, K. Miura, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Establishment of a 5-fluorouracil-resistant triple-negative breast cancer cell line.

H. Wanibuchi, K. Miura, H. Iwao, 2013, International journal of oncology.

Involvement of Apoptosis Signal-Regulating Kinase-1 on Angiotensin II-Induced Monocyte Chemoattractant Protein-1 Expression

Shokei Kim, H. Iwao, H. Ichijo, 2004, Arteriosclerosis, thrombosis, and vascular biology.

FACTOR XA INHIBITION BY RIVAROXABAN ATTENUATES CARDIAC REMODELING DUE TO HYPOXIC STRESS VIA PAR-2/ERK/NF-κB SIGNALING PATHWAY

Y. Izumi, M. Yoshiyama, Y. Ijiri, 2016 .

Abstract 13846: Factor Xa Inhibition Prevents Cardiac Remodeling Induced by Intermittent Hypoxia in Sleep Apnea Model Mice

Y. Izumi, M. Yoshiyama, Y. Ijiri, 2015 .

Preliminary observations of passive exercise using whole body periodic acceleration on coronary microcirculation and glucose tolerance in patients with type 2 diabetes.

M. Fujita, Y. Izumi, H. Ogawa, 2012, Journal of cardiology.

Augmented O-GlcNAcylation attenuates intermittent hypoxia-induced cardiac remodeling through the suppression of NFAT and NF-κB activities in mice

Y. Izumi, M. Yoshiyama, T. Nakagawa, 2019, Hypertension Research.

Microminipig, a Non-rodent Experimental Animal Optimized for Life Science Research: In Vivo Proarrhythmia Models of Drug-Induced Long QT Syndrome: Development of Chronic Atrioventricular Block Model of Microminipig.

H. Yamazaki, Y. Izumi, A. Sugiyama, 2011, Journal of pharmacological sciences.