B. Posner

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Transcriptional regulation by insulin: from the receptor to the gene.

Catherine Mounier, C. Mounier, B. Posner, 2006, Canadian journal of physiology and pharmacology.

Regulation of hepatic insulin-like growth factor-binding protein-1 gene expression by insulin: central role for mammalian target of rapamycin independent of forkhead box O proteins.

C. Mounier, B. Posner, V. Dumas, 2006, Endocrinology.

Regulation of Histone Deacetylase 4 by Binding of 14-3-3 Proteins

Barry I. Posner, N. Bertos, Xiang-Jiao Yang, 2000, Molecular and Cellular Biology.

Epidermal Growth Factor-induced Vacuolar (H+)-ATPase Assembly

B. Posner, V. Dumas, Yanqing Xu, 2012, The Journal of Biological Chemistry.

Specific inhibition by hGRB10ζ of insulin-induced glycogen synthase activation: evidence for a novel signaling pathway

David Y. Thomas, C. Mounier, B. Posner, 2001, Molecular and Cellular Endocrinology.

Selective Activation of the Rat Hepatic Endosomal Insulin Receptor Kinase

P G Drake, P. Drake, B. Posner, 1995, The Journal of Biological Chemistry.

Compartmentalization of EGFR in cellular membranes: Role of membrane rafts

B. Posner, A. Balbis, 2010, Journal of cellular biochemistry.

Compartmentalization of epidermal growth factor receptor in liver plasma membrane

B. Posner, A. Balbis, Ye Wang, 2009, Journal of cellular biochemistry.

Cellular signalling: Peptide hormones and growth factors.

B. Posner, S. Laporte, 2010, Progress in brain research.

Assessment of internalization and endosomal signaling: studies with insulin and EGF.

B. Posner, J. Bergeron, 2014, Methods in enzymology.

Uptake of insulin and other ligands into receptor-rich endocytic components of target cells: the endosomal apparatus.

B. Posner, J. Bergeron, J. Cruz, 1985, Annual review of physiology.

Polypeptide hormones: intracellular receptors and internalization.

B. Posner, J. Bergeron, A. Verma, 1981, Recent progress in hormone research.

The G protein‐coupled receptor kinase‐2 is a TGFβ‐inducible antagonist of TGFβ signal transduction

B. Posner, V. Dumas, J. Lebrun, 2005 .

The G protein-coupled receptor kinase-2 is a TGFb- inducible antagonist of TGFb signal transduction

B. Posner, J. Lebrun, J. Ho, 2005 .

Insulin Signalling: The Inside Story.

B. Posner, 2017, Canadian journal of diabetes.

Peptide Hormones and Growth Factors: Signaling Mechanisms in Endosomes

B. Posner, S. Laporte, 2014 .

Insulin receptor kinase-associated phosphotyrosine phosphatases in hepatic endosomes: assessing the role of phosphotyrosine phosphatase-1B.

M. Tremblay, F. Gu, B. Posner, 2006, Endocrinology.

Effect of Insulin on Caveolin-enriched Membrane Domains in Rat Liver*

C. Mounier, B. Posner, A. Balbis, 2004, Journal of Biological Chemistry.

Effect of Inhibiting Vacuolar Acidification on Insulin Signaling in Hepatocytes*

B. Posner, V. Dumas, A. Balbis, 2004, Journal of Biological Chemistry.

Insulin receptor-associated protein tyrosine phosphatase(s): Role in insulin action

P. Drake, B. Posner, 1998, Molecular and Cellular Biochemistry.

Regulation of insulin receptor kinase activity by endosomal processes: possible areas for therapeutic intervention.

B. Posner, 2003, Current opinion in investigational drugs.

The role of insulin dissociation from its endosomal receptor in insulin degradation

K. Siddle, P. Seabright, B. Posner, 2000, Molecular and Cellular Endocrinology.

Tyrosine phosphorylation of p97 regulates transitional endoplasmic reticulum assembly in vitro.

E. Chevet, N. Tonks, B. Posner, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Association of phosphatidylinositol 3-kinase with the insulin receptor: compartmentation in rat liver.

P. Drake, B. Posner, Jiong Wu, 2000, American journal of physiology. Endocrinology and metabolism.

Compartmentalization and insulin-induced translocations of insulin receptor substrates, phosphatidylinositol 3-kinase, and protein kinase B in rat liver.

B. Posner, A. Balbis, J. Bergeron, 2000, Endocrinology.

The Insulin Receptor Kinase

B. Posner, 2000 .

ATP-dependent Desensitization of Insulin Binding and Tyrosine Kinase Activity of the Insulin Receptor Kinase

B. Posner, R. Faure, J. Bergeron, 1998, The Journal of Biological Chemistry.

Insulin receptor internalization and signalling

P. Drake, B. Posner, J. Bergeron, 1998 .

Endosomes, receptor tyrosine kinase internalization and signal transduction

B. Posner, J. Bergeron, G. M. Guglielmo, 1995, Bioscience reports.

Effect of colchicine on the uptake of prolactin and insulin into Golgi fractions of rat liver

B. Posner, J. Bergeron, A. Verma, 1982, The Journal of cell biology.

Effect of colchicine on internalization of prolactin in female rat liver: an in vivo radioautographic study

B. Posner, J. Bergeron, R. Rachubinski, 1983, The Journal of cell biology.

Insulin and Insulin Receptor Uptake into Rat Liver: Chloroquine Action on Receptor Recycling

B. Posner, J. Bergeron, M. N. Khan, 1985, Diabetes.

Epidermal growth factor receptor kinase translocation and activation in vivo.

B. Posner, J. Bergeron, D. Kay, 1986, The Journal of biological chemistry.

Differential and analytical subfractionation of rat liver components internalizing insulin and prolactin.

B. Posner, J. Bergeron, N. Searle, 1986, Biochemistry.

Peroxide(s) of vanadium: a novel and potent insulin-mimetic agent which activates the insulin receptor kinase.

I. G. Fantus, G. Deragon, B. Posner, 1987, Biochemical and biophysical research communications.

The endosomal apparatus and transmembrane signalling.

B. Posner, J. Bergeron, D. Kay, 1988, Advances in experimental medicine and biology.

Ligand-mediated internalization, recycling, and downregulation of the epidermal growth factor receptor in vivo [published erratum appears in J Cell Biol 1990 Jan;110(1):following 227]

P. H. Cameron, B. Posner, I. Wada, 1989, The Journal of cell biology.

Ligand-mediated autophosphorylation activity of the epidermal growth factor receptor during internalization

P. H. Cameron, B. Posner, J. Bergeron, 1989, The Journal of cell biology.

Internalization and activation of the rat liver insulin receptor kinase in vivo.

B. Posner, J. Burgess, J. Bergeron, 1989, The Journal of biological chemistry.

Association of the tyrosine phosphorylated epidermal growth factor receptor with a 55-kD tyrosine phosphorylated protein at the cell surface and in endosomes

B. Posner, I. Wada, J. Bergeron, 1992, The Journal of cell biology.

Decrease in beta-subunit phosphotyrosine correlates with internalization and activation of the endosomal insulin receptor kinase.

N. Ling, B. Posner, I. Wada, 1992, The Journal of biological chemistry.

Potential role of endosomes in transmembrane signaling.

B. Posner, J. Burgess, J. Bergeron, 1993, Sub-cellular biochemistry.

Binding of Insulin by Monkey and Pig Hypothalamus

S. Genuth, B. Posner, B. Landau, 1983, Diabetes.

Cellular basis of direct insulin action in the central nervous system.

B. Posner, M. Van Houten, M. Houten, 1981, Diabetologia.

Endosomal proteolysis of internalized proteins

B. Posner, J. Bergeron, F. Authier, 1996, FEBS letters.

Prolactin enhancement of its own uptake at the choroid plexus.

B. Posner, L. Mangurian, R. J. Walsh, 1992, Endocrinology.

Insulin binds to brain blood vessels in vivo

B. Posner, M. Houten, 1979, Nature.

Insulin-binding sites in the rat brain: in vivo localization to the circumventricular organs by quantitative radioautography.

B. Posner, J. Brawer, M. Van Houten, 1979, Endocrinology.

The effect of a slightly acidic somatomedin peptide (ILAs) on the sulphation of proteoglycans from articular and growth plate chondrocytes in culture.

B. Posner, R. Rappaport, H. Guyda, 1978, Acta endocrinologica.

Peroxovanadate and insulin action in adipocytes from NIDDM patients. Evidence against a primary defect in tyrosine phosphorylation

P. Jansson, B. Posner, J. Eriksson, 1997, Diabetologia.

The G protein-coupled receptor kinase-2 is a TGFbeta-inducible antagonist of TGFbeta signal transduction.

B. Posner, V. Dumas, J. Lebrun, 2005, The EMBO journal.

Effects of insulin-like growth factors on adult male rat pituitary function in tissue culture.

B. Posner, C. Goodyer, H. Guyda, 1984, Endocrinology.

The distribution of lactogen receptors in the mammalian hypothalamus: an in vitro autoradiographic analysis of the rabbit and rat

B. Posner, L. Mangurian, R. J. Walsh, 1990, Brain Research.

A method for quantitation of protein in the presence of Percoll.

B. Posner, M. N. Khan, R. J. Khan, 1981, Analytical biochemistry.

Hepatic protein phosphotyrosine phosphatase. Dephosphorylation of insulin and epidermal growth factor receptors in normal and alloxan diabetic rats.

P. Gruppuso, B. Posner, D. Brautigan, 1990, The Journal of clinical investigation.

Concentration of intracellular hepatic apolipoprotein E in Golgi apparatus saccular distensions and endosomes

B. Posner, J. Bergeron, J. Ahluwalia, 1994, The Journal of cell biology.

Insulin-degrading enzyme.

B. Posner, J. Bergeron, F. Authier, 1996, Clinical and investigative medicine. Medecine clinique et experimentale.

The augmentation of insulin-like growth factor-I messenger ribonucleic acid in cultured rat hepatocytes: activation of protein kinase-A and -C is necessary, but not sufficient.

B. Posner, Z. Kachra, C. Yang, 1994, Endocrinology.

The regulation of insulin-like growth factor-binding protein 1 messenger ribonucleic acid in cultured rat hepatocytes: the roles of glucagon and growth hormone.

B. Posner, L. Murphy, Z. Kachra, 1994, Endocrinology.

Endosomal proteolysis of insulin by an acidic thiol metalloprotease unrelated to insulin degrading enzyme.

B. Posner, J. Bergeron, R. Rachubinski, 1994, The Journal of biological chemistry.

Radioautographic identification of lactogen binding sites in rat median eminence using 125I-human growth hormone: Evidence for a prolactin “short-loop” feedback site

B. Posner, R. J. Walsh, M. Houten, 2004, Experimental Brain Research.

Internalization of Insulin and Its Receptor: Role in Signaling

B. Posner, J. Bergeron, M. N. Khan, 1987 .

Polypeptide hormone receptors: characteristics and applications.

B. Posner, 1975, Canadian journal of physiology and pharmacology.

Peroxovanadate but not vanadate exerts insulin-like effects in human adipocytes

B. Posner, P. Lönnroth, U. Smith, 1993, Diabetologia.

A stable peroxovanadium compound with insulin-like action in human fat cells

B. Posner, P. Lönnroth, U. Smith, 1996, Diabetologia.

Separation of biological variant insulin molecules from different species by reversed-phase high-performance liquid chromatography (HPLC).

B. Posner, J. Crawhall, D. Kalant, 1985, Biochemical medicine.

Galactose transfer to endogenous acceptors within Golgi fractions of rat liver

B. Posner, J. Bergeron, R. Rachubinski, 1982, The Journal of cell biology.

Effects of peroxovanadate and vanadate on insulin binding, degradation and sensitivity in rat adipocytes.

B. Posner, U. Smith, J. Eriksson, 1996, Biochimica et biophysica acta.

Homologous induction of growth hormone receptors in cultured rat hepatocytes

B. Posner, I. Barash, 1989, Molecular and Cellular Endocrinology.

Prolactin (PRL) receptor induction in cultured rat hepatocytes: dual regulation by PRL and growth hormone.

W. Cromlish, B. Posner, I. Barash, 1988, Endocrinology.

Pituitary-dependent growth hormone receptors in rabbit and sheep liver.

B. Posner, B. Patel, A. Vézinhet, 1980, Endocrinology.

Decreased sensitivity of old and progeric human fibroblasts to a preparation of factors with insulinlike activity.

C. Harley, S. Goldstein, B. Posner, 1981, The Journal of clinical investigation.

Intracellular polypeptide hormone receptors. Characterization of insulin binding sites in Golgi fractions from the liver of female rats.

B. Posner, J. Bergeron, Z. Josefsberg, 1978, The Journal of biological chemistry.

Insulin and the efficacy of total parenteral nutrition.

B. Posner, H. Shizgal, 1989, The American journal of clinical nutrition.

Insulin, insulin-like activity and the human placenta.

B. Posner, H. Guyda, Y. Omori, 1977, Journal of steroid biochemistry.

Cellular basis of direct insulin action in the central nervous system

B. Posner, M. Houten, 2004, Diabetologia.

INTRACELLULAR POLYPEPTIDE HORMONE RECEPTORS: LOCATION AND SIGNIFICANCE

B. Posner, J. Bergeron, 1981 .

Induction of a lactogenic receptor in rat liver: influence of estrogen and the pituitary.

P. Kelly, B. Posner, H. Friesen, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Effect of chloroquine on the internalization of 125I-insulin into subcellular fractions of rat liver. Evidence for an effect of chloroquine on Golgi elements.

B. Posner, J. Bergeron, M. N. Khan, 1982, The Journal of biological chemistry.

Prolactin receptors in rat liver: possible induction by prolactin.

P. Kelly, B. Posner, H. Friesen, 1975, Science.

Insulin-like growth factor-binding proteins in hypophysectomized rat liver: characterization and subcellular localization.

B. Posner, M. N. Khan, B. Patel, 1988, Endocrinology.

Isolation of insulin degradation products from endosomes derived from intact rat liver.

W. Duckworth, B. Posner, J. Bergeron, 1988, The Journal of biological chemistry.

Internalization of hormone receptor complexes: route and significance.

B. Posner, J. Bergeron, D. Kay, 1986, Advances in experimental medicine and biology.

Activation of HIV-1 Long Terminal Repeat Transcription and Virus Replication via NF-κB-dependent and -independent Pathways by Potent Phosphotyrosine Phosphatase Inhibitors, the Peroxovanadium Compounds*

M. Tremblay, B. Posner, M. Olivier, 1997, The Journal of Biological Chemistry.

Binding and uptake of 125I-insulin into rat liver hepatocytes and endothelium. An in vivo radioautographic study

B. Posner, J. Bergeron, A. Hand, 1979, The Journal of cell biology.

Effect of insulin-like growth factors on human foetal, adult normal and tumour pituitary function in tissue culture.

B. Posner, C. Goodyer, J. Hardy, 1986, Acta endocrinologica.

A protein-tyrosine phosphatase with sequence similarity to the SH2 domain of the protein-tyrosine kinases

P. Chrétien, B. Posner, S. Shen, 1991, Nature.

Insulin-like peptides stimulate metabolism but not proliferation of human fibroblasts.

C. Harley, S. Goldstein, B. Posner, 1980, The American journal of physiology.

The ontogeny of specific prolactin binding sites in the rat choroid plexus.

B. Posner, W. Silverman, R. J. Walsh, 1986, Brain research.

Prolactin binding sites in the rat brain.

B. Posner, J. Brawer, R. J. Walsh, 1978, Science.

Epidermal Growth Factor-induced Phosphatidylinositol 3-Kinase Activation and DNA Synthesis

C. Mounier, B. Posner, Jiong Wu, 2000, The Journal of Biological Chemistry.

Epidermal growth factor and insulin-induced deoxyribonucleic acid synthesis in primary rat hepatocytes is phosphatidylinositol 3-kinase dependent and dissociated from protooncogene induction.

C. Mounier, B. Posner, C. J. Band, 1999, Endocrinology.

Free insulin-like growth factor I (IGF-I) and IGF-II in human saliva.

B. Posner, H. Guyda, D. Costigan, 1988, The Journal of clinical endocrinology and metabolism.

Regulation of lactogen specific binding sites in rat liver: studies on the role of lactogens and estrogen.

B. Posner, 1976, Endocrinology.

Endosomes and Cell Signalling

B. Posner, J. Bergeron, 1993 .

Signaling of Receptor Tyrosine Kinases Across the Endosomal Membrane

B. Posner, J. Bergeron, 1992 .

Characterization of insulin-like growth factor receptors in rat anterior pituitary, hypothalamus, and brain.

B. Posner, C. Goodyer, H. Guyda, 1984, Endocrinology.

Studies of insulin, growth hormone and prolactin binding: ontogenesis, effects of sex and pregnancy.

P. Kelly, B. Posner, H. Friesen, 1974, Endocrinology.

Tunicamycin sensitivity of prolactin, insulin and epidermal growth factor receptors in rat liver plasmalemma

B. Posner, J. Bergeron, S. Savoie, 1986, Molecular and Cellular Endocrinology.

Ribonucleic acid synthesis in experimental cardiac hypertrophy in rats. II. Aspects of regulation.

B. Posner, B. Fanburg, 1968, Circulation research.

Ribonucleic Acid Synthesis in Experimental Cardiac Hypertrophy in Rats: I. Characterization and Kinetics of Labeling

B. Posner, B. Fanburg, 1968, Circulation research.

Peptide hormone receptors in intracellular structures from rat liver.

B. Posner, J. Bergeron, M. N. Khan, 1985, Methods in enzymology.

Immunoassay of a somatomedin-binding protein from human amniotic fluid: levels in fetal, neonatal, and adult sera.

B. Posner, S. Drop, H. Guyda, 1984, The Journal of clinical endocrinology and metabolism.

Proteolysis of Glucagon within Hepatic Endosomes by Membrane-associated Cathepsins B and D (*)

B. Posner, J. Bergeron, A. Bell, 1995, The Journal of Biological Chemistry.

Megalin is an endocytic receptor for insulin.

B. Posner, J. Bergeron, M. Farquhar, 1998, Journal of the American Society of Nephrology : JASN.

Internalization of insulin into rat liver Golgi elements. Evidence for vesicle heterogeneity and the path of intracellular processing.

B. Posner, J. Bergeron, M. N. Khan, 1982, The Journal of biological chemistry.

Differential kinetics and sensitivity to chloroquine of receptor-mediated insulin and prolactin endocytosis in liver parenchymal cells.

B. Posner, J. Bergeron, M. N. Khan, 1986, Biochimica et biophysica acta.

Prolactin uptake into liver endocytic components. Reduced sensitivity to chloroquine.

B. Posner, J. Bergeron, M. N. Khan, 1985, Biochimica et biophysica acta.

Gab2 tyrosine phosphorylation by a pleckstrin homology domain-independent mechanism: role in epidermal growth factor-induced mitogenesis.

C. Mounier, B. Posner, A. Balbis, 2003, Molecular endocrinology.

Degradation of the cleaved leader peptide of thiolase by a peroxisomal proteinase.

B. Posner, J. Bergeron, R. Rachubinski, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Insulin interaction with the central nervous system: nature and possible significance

B. Posner, 1987, Proceedings of the Nutrition Society.

Increase in the type 2 insulin-like growth factor receptors in the rat kidney during compensatory growth.

C. Polychronakos, B. Posner, H. Guyda, 1985, Biochemical and biophysical research communications.

Mannose 6-phosphate increases the affinity of its cation-independent receptor for insulin-like growth factor II by displacing inhibitory endogenous ligands.

C. Polychronakos, B. Posner, H. Guyda, 1988, Biochemical and biophysical research communications.

The differential regulation by glucagon and growth hormone of insulin-like growth factor (IGF)-I and IGF binding proteins in cultured rat hepatocytes.

B. Posner, C. Yannopoulos, I. Barash, 1991, Endocrinology.

Bisperoxovanadium compounds: synthesis and reactivity of some insulin mimetic complexes

B. Posner, A. Shaver, D. A. Hall, 1995 .

Intracellular hormone receptors: evidence for insulin and lactogen receptors in a unique vesicle sedimenting in lysosome fractions of rat liver.

B. Posner, J. Bergeron, A. Verma, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Polypeptide hormone receptors in vivo: demonstration of insulin binding to adrenal gland and gastrointestinal epithelium by quantitative radioautography.

B. Posner, J. Bergeron, R. Rachubinski, 1980, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Specific binding and internalization of blood-borne [125I]-iodoinsulin by neurons of the rat area postrema.

B. Posner, M. Van Houten, 1981, Endocrinology.

Immunocytochemical detection of insulin in rat hypothalamus and its possible uptake from cerebrospinal fluid.

S. Woods, D. Porte, B. Posner, 1983, Endocrinology.

Acute Reversal of the Enhanced Insulin Action in Trained Athletes: Association with Insulin Receptor Changes

C. Polychronakos, B. Posner, R. Burstein, 1985, Diabetes.

A receptor-mediated mechanism for the transport of prolactin from blood to cerebrospinal fluid.

F. Slaby, B. Posner, R. J. Walsh, 1987, Endocrinology.

Phosphatidylinositol 3*-Kinase and p70 Are Required for Insulin but Not Bisperoxovanadium 1,10-Phenanthroline (bpV(phen)) Inhibition of Insulin-like Growth Factor Binding Protein Gene Expression EVIDENCE FOR MEK-INDEPENDENT ACTIVATION OF MITOGEN-ACTIVATED PROTEIN KINASE BY bpV(phen)*

B. Posner, C. J. Band, 1996 .

Determination of insulin and insulin-like growth factors in the ovarian circulation.

B. Posner, R. Hemmings, H. Guyda, 1990, Fertility and sterility.

Insulin-like growth factor (IGF) binding in hypophysectomized rat liver microsomes: alteration by a soluble binding moiety.

B. Posner, B. Patel, H. Guyda, 1987, Reproduction, nutrition, developpement.

Receptors for insulin-like growth factors in rabbit articular and growth plate chondrocytes in culture.

B. Posner, M. Corvol, H. Guyda, 1983, Experimental cell research.

Receptors for the insulin-like growth factors on human erythrocytes.

C. Polychronakos, B. Posner, H. Guyda, 1983, The Journal of clinical endocrinology and metabolism.

Ontogeny of Growth Factor Receptors in the Human Placenta

C. Deal, B. Posner, H. Guyda, 1982, Pediatric Research.

Effects of mannose-6-phosphate on receptor-mediated endocytosis of insulin-like growth factor-II.

C. Polychronakos, B. Posner, H. Guyda, 1990, Endocrinology.

Receptor-mediated endocytosis of [125I]insulin into pancreatic acinar cells in vivo.

B. Posner, J. Bergeron, J. Cruz, 1984, Endocrinology.

Insulin Internalization as Studied by Subcellular Fractionation and Electron-Microscopic Radioautography

B. Posner, J. Bergeron, M. N. Khan, 1984 .

Radioreceptor assay of insulin-like peptides in human plasma: growth hormone dependence and correlation with sulfation activity by two bioassays.

B. Posner, R. Rappaport, H. Guyda, 1979, The Journal of clinical endocrinology and metabolism.

Characterization of lactogen binding sites in choroid plexus

B. Posner, B. Patel, R. J. Walsh, 2004, Experimental Brain Research.

Origin of insulin-receptive nerve terminals in rat median eminence.

S. Gauthier, D. Nance, B. Posner, 1983, Endocrinology.

THE HYPOTHALMIC MEDIAN EMINENCE OF THE HOMOZYGOUS BRATTLEBORO RAT IS DEFICIENT IN CALCITONIN‐SPECIFIC BINDING SITES *

B. Posner, D. Goltzman, A. Rizzo, 1982, Annals of the New York Academy of Sciences.

Brain receptors for blood-borne calcitonin in rats: circumventricular localization and vasopressin-resistant deficiency in hereditary diabetes insipidus.

B. Posner, D. Goltzman, A. Rizzo, 1982, Endocrinology.

Radioautographic localization of specific binding sites for blood-borne angiotensin II in the rat brain

E. Schiffrin, B. Posner, R. Boucher, 1980, Brain Research.

In vivo studies on the initial localization and fate of polypeptide hormone receptors by the technique of quantitative radioautography.

B. Posner, J. Bergeron, 1979, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Octreotide inhibits insulin-like growth factor-I hepatic gene expression in the hypophysectomized rat: evidence for a direct and indirect mechanism of action.

B. Posner, P. Brazeau, O. Serri, 1992, Endocrinology.

Clinical Endocrinology 6 Metabolism Editor-in-chief: Delbert A. Fisher

R. Rubin, J. Flier, M. Schambelan, 2022 .

Insulin Disposition in the Isolated Perfused Rat Heart: Effect of “Bound” Insulin

B. Posner, S. Sotman, H. N. Antoniades, 1968, Diabetes.

Intracellular (Golgi) receptors for insulinlike peptides in rat liver.

B. Posner, H. Guyda, R. M. Gonzalez, 1980, Canadian journal of biochemistry.

Effect of Colchicine on Female Rat Liver: An In Internalization of Prolactin in Vivo Radioautographic Study

B. Posner, J. Bergeron, R. Rachubinski, 2003 .

Different Forms of Vanadate on Sugar Transport in Insulin Target and Nontarget Cells

B. Posner, R. Germinario, S. Colby-Germinario, 2002, Journal of biomedicine & biotechnology.

Diurnal rhythm of plasma immunoreactive beta-endorphin and its relationship to sleep stages and plasma rhythms of cortisol and prolactin.

C. Guilleminault, B. Posner, A. Goldstein, 1981, The Journal of clinical endocrinology and metabolism.

Partial purification and characterization of a binding protein for insulin-like activity (ILAs) in human amniotic fluid: a possible inhibitor of insulin-like activity.

B. Posner, H. Guyda, G. Valiquette, 1979, Acta endocrinologica.

Periodinates: a new class of protein tyrosine phosphatase inhibitors.

B. Posner, G. Just, K. Leung, 1999, Bioorganic & medicinal chemistry letters.

Hormone receptors in the epiphysial cartilage.

B. Posner, R. Cruess, S. Solomon, 1984, The Journal of endocrinology.

Peroxovanadium‐mediated protection against murine leishmaniasis: role of the modulation of nitric oxide

P. Gros, B. Posner, M. Olivier, 2000, European journal of immunology.

Insulin mimetic peroxovanadium complexes: preparation and structure of potassium oxodiperoxo(pyridine-2-carboxylato)vanadate(V), K2[VO(O2)2(C5H4NCOO)].2H2O, and potassium oxodiperoxo(3-hydroxypyridine-2-carboxylato)vanadate(V), K2[VO(O2)2(OHC5H3NCOO)].3H2O, and their reactions with cysteine

B. Posner, A. Shaver, D. A. Hall, 1993 .

Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics.

I. G. Fantus, B. Posner, R. Faure, 1994, The Journal of biological chemistry.

The chemistry of peroxovanadium compounds relevant to insulin mimesis

B. Posner, A. Shaver, D. A. Hall, 1995, Molecular and Cellular Biochemistry.

Hypoglycemic Effects of Peroxovanadium Compounds in Sprague-Dawley and Diabetic BB Rats

B. Posner, A. Bevan, A. Shaver, 1995, Diabetes.

In vivo insulin mimetic effects of pV compounds: role for tissue targeting in determining potency.

P. Drake, B. Posner, A. Bevan, 1995, The American journal of physiology.

Peroxovanadium compounds: Biolgoical actions and mechanism of insulin-mimesis

P. Drake, B. Posner, A. Bevan, 1995, Molecular and Cellular Biochemistry.

Pervanadate [peroxide(s) of vanadate] mimics insulin action in rat adipocytes via activation of the insulin receptor tyrosine kinase.

I. G. Fantus, G. Deragon, B. Posner, 1989, Biochemistry.

A role for tyrosine phosphorylation in both activation and inhibition of the insulin receptor tyrosine kinase in vivo.

P G Drake, P. Drake, B. Posner, 1996, Endocrinology.

Early signaling events triggered by peroxovanadium [bpV(phen)] are insulin receptor kinase (IRK)-dependent: specificity of inhibition of IRK-associated protein tyrosine phosphatase(s) by bpV(phen).

B. Posner, V. Dumas, J. Contreres, 1997, Molecular endocrinology.

Increased plasma somatomedin reactivity in chronic renal failure as determined by acid gel filtration and radioreceptor assay.

B. Posner, P. Robitaille, H. Guyda, 1978, The Journal of clinical endocrinology and metabolism.

Characterization of rat liver endosomal fractions. In vivo activation of insulin-stimulable receptor kinase in these structures.

B. Posner, J. Bergeron, J J Bergeron, 1986, The Journal of biological chemistry.

Endocytosis of peptide hormones and other ligands.

B. Posner, J. Bergeron, M. N. Khan, 1982, Endocrine reviews.

Studies of insulin, growth hormone and prolactin binding: tissue distribution, species variation and characterization.

P. Kelly, B. Posner, H. Friesen, 1974, Endocrinology.

Cystathionine -synthase. Studies of hydrogen exchange reactions.

M. Flavin, B. Posner, 1972, The Journal of biological chemistry.

Arrest at the G2/M transition of the cell cycle by protein‐tyrosine phosphatase inhibition: Studies on a neuronal and a glial cell line

B. Posner, R. Faure, A. Shaver, 1995, Journal of cellular biochemistry.

Characterization and modulation of growth hormone and prolactin binding in mouse liver.

B. Posner, 1976, Endocrinology.

Insulin Receptors in Human and Animal Placental Tissue

B. Posner, 1974, Diabetes.

Cystathionine -synthase. The nature of intramolecular proton shifts in the elimination reaction.

M. Flavin, B. Posner, 1972, The Journal of biological chemistry.

Polypeptide hormone receptors

B. Posner, 1985 .

Phosphatidylinositol 3′-Kinase and p70s6k Are Required for Insulin but Not Bisperoxovanadium 1,10-Phenanthroline (bpV(phen)) Inhibition of Insulin-like Growth Factor Binding Protein Gene Expression

B. Posner, C. J. Band, 1997, The Journal of Biological Chemistry.

Specificity of insulin-like growth factor binding to type-II IGF receptors in rabbit mammary gland and hypophysectomized rat liver.

C. Polychronakos, B. Posner, C. Goodyer, 1987, Biochemical and biophysical research communications.

Partial purification, characterization, and assay of a slightly acidic insulin-like peptide (ILAs) from human plasma.

C. Harley, S. Goldstein, B. Posner, 1978, The Journal of clinical endocrinology and metabolism.

Epidermal Growth Factor-induced DNA Synthesis

C. Mounier, B. Posner, V. Dumas, 2003, The Journal of Biological Chemistry.

Studies on Components of RNA in Cardiac Muscle with Emphasis on the Rapidly Labeled 4 to 18 S Fraction

B. Posner, B. Fanburg, 1966, Circulation research.

Interaction of the Grb10 Adapter Protein with the Raf1 and MEK1 Kinases*

David Y. Thomas, B. Posner, A. Nantel, 1998, The Journal of Biological Chemistry.

Epidermal Growth Factor and Insulin-Induced Deoxyribonucleic Acid Synthesis in Primary Rat Hepatocytes Is Phosphatidylinositol 3-Kinase Dependent and Dissociated from Protooncogene Induction1.

C. Mounier, B. Posner, C. J. Band, 1999, Endocrinology.

Intracellular signal transduction: The role of endosomes

P. Drake, B. Posner, A. Bevan, 1996, Trends in Endocrinology & Metabolism.

Compartmentalized signal transduction by receptor tyrosine kinases.

G. M. Di Guglielmo, B. Posner, J. Bergeron, 1995, Trends in Cell Biology.

The uptake of prolactin into female rat liver. Concentration of intact hormone in the Golgi apparatus.

B. Posner, J. Bergeron, Z. Josefsberg, 1979, The Journal of biological chemistry.

A protein-tyrosine phosphatase with sequence similarity to the SH2 domain of the protein-tyrosine kinases

P. Chrétien, B. Posner, S. Shen, 1991, Nature.

Insulin Action

N. Dhalla, B. Posner, A. Srivastava, 1998, Developments in Molecular and Cellular Biochemistry.

Prolactin receptors in the primate choroid plexus.

B. Posner, L. Mangurian, R. J. Walsh, 1990, Journal of anatomy.

Effects of hypophysectomy, ovariectomy, and cycloheximide on specific binding sites for lactogenic hormones in rat liver.

P. Kelly, B. Posner, H. Friesen, 1975, Endocrinology.

Circumventricular organs: receptors and mediators of direct peptide hormone action on brain.

B. Posner, M. Van Houten, M. Houten, 1983, Advances in metabolic disorders.

Radioautographic visualization of in vivo insulin binding to the exocrine pancreas.

B. Posner, J. Bergeron, R. Rachubinski, 1980, Endocrinology.

Global analysis of protein phosphorylation networks in insulin signaling by sequential enrichment of phosphoproteins and phosphopeptides.

A. Pshezhetsky, B. Posner, Yanqing Xu, 2012, Molecular bioSystems.

Spatial and Temporal Regulation of Receptor Tyrosine Kinase Activation and Intracellular Signal Transduction.

Sophie Dahan, G. M. Di Guglielmo, B. Posner, 2016, Annual review of biochemistry.

Knockout of USP19 Deubiquitinating Enzyme Prevents Muscle Wasting by Modulating Insulin and Glucocorticoid Signaling

R. Sladek, O. Bathe, S. Wing, 2018, Endocrinology.

Stimulation of insulin-like growth factor II receptor binding and insulin receptor kinase activity in rat adipocytes. Effects of vanadate and H2O2.

I. G. Fantus, G. Deragon, B. Posner, 1987, The Journal of biological chemistry.

Insulin-like growth factors: a role in growth hormone negative feedback and body weight regulation via brain.

B. Posner, G. Tannenbaum, H. Guyda, 1983, Science.

Characterization of the insulin-like growth factor (IGF) receptor hi K562 erythroleukemia cells; evidence for a biological function for the type II IGF receptor

B. Posner, H. Guyda, B. Foster, 1988, Molecular and Cellular Endocrinology.

Quantitative analysis of a proteome by N-terminal stable-isotope labelling of tryptic peptides.

A. Pshezhetsky, E. Levy, B. Posner, 2007, Rapid communications in mass spectrometry : RCM.

Receptors for insulin-like peptides (ILAs) in rat reticulocytes and erythrocytes.

P. Thomopoulos, U. Testa, B. Posner, 1981, Endocrinology.

Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf‐1 by EGF but not insulin in liver parenchyma.

G. M. Di Guglielmo, B. Posner, J. Bergeron, 1994, The EMBO journal.

Modulation of interferon-gamma-induced macrophage activation by phosphotyrosine phosphatases inhibition. Effect on murine Leishmaniasis progression.

M. Tremblay, B. Posner, M. Olivier, 1998, The Journal of biological chemistry.

Mechanism of Insulin Mimetic Action of Peroxovanadium Compounds

B. Posner, A. Shaver, C. Yang, 1998 .

Peroxovanadium compounds as inhibitors of angiogenesis

B. Posner, P. Savard, C. Doillon, 2004, Angiogenesis.

Insulin receptor internalization and signalling

Barry I. Posner, John J.M. Bergeron, G. M. Di Guglielmo, 1998, Molecular and Cellular Biochemistry.

Characterization of the structure and glycosylation properties of intracellular and cell surface rat hepatic prolactin receptors.

P. Kelly, B. Posner, J. Bergeron, 1992, Endocrinology.

Different regulation of insulin receptors in intracellular (Golgi) and plasma membranes from livers of obese and lean mice.

B. Posner, J. Bergeron, Z. Josefsberg, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Intracellular polypeptide hormone receptors. The demonstration of specific binding sites for insulin and human growth hormone in Golgi fractions isolated from the liver of female rats.

B. Posner, J. Bergeron, Z. Josefsberg, 1978, The Journal of biological chemistry.

Effect of colchicine on internalization of prolactin in female rat liver: an in vivo radioautographic study

B. Posner, J. Bergeron, R. Rachubinski, 1983, The Journal of cell biology.

Intracellular polypeptide hormone receptors. Characterization and induction of lactogen receptors in the Golgi apparatus of rat liver.

B. Posner, Z. Josefsberg, J. Bergerson, 1979, The Journal of biological chemistry.

Binding and uptake of [125I]iodoprolactin by epithelial cells of the rat choroid plexus: an in vivo autoradiographic analysis.

B. Posner, B. Patel, R. J. Walsh, 1984, Endocrinology.

Characterization of the prolactin receptor in cell fractions from rat liver

B. Posner, D. Borst, M. Sayare, 1985, Molecular and Cellular Endocrinology.

The dephosphorylation of insulin and epidermal growth factor receptors. Role of endosome-associated phosphotyrosine phosphatase(s).

B. Posner, R. Faure, J. Bergeron, 1992, The Journal of biological chemistry.

Vanadate stimulation of IGF binding to rat adipocytes.

I. G. Fantus, B. Posner, S. Kadota, 1986, Biochemical and biophysical research communications.

The effect of growth hormone treatment on somatomedin levels in growth hormone-deficient children.

B. Posner, H. Friesen, H. Dean, 1982, The Journal of clinical endocrinology and metabolism.

Quantitative in vivo autoradiographic localization of [125I-Tyr11]somatostatin-14- and [Leu8,D-Trp22-125I-Tyr25]somatostatin-28-binding sites in rat brain.

B. Posner, C. B. Srikant, Y. Patel, 1986, Endocrinology.

Internalization of insulin: structures involved and significance.

B. Posner, J. Bergeron, M. N. Kahn, 1985, Advances in experimental medicine and biology.

Developing Vanadium as an Antidiabetic or Anticancer Drug: A Clinical and Historical Perspective.

B. Posner, D. Crans, LaRee Henry, 2019, Metal ions in life sciences.

Selective degradation of insulin within rat liver endosomes

D G Kay, B. Posner, J. Bergeron, 1990, The Journal of cell biology.

Differential intracellular compartmentalization of phosphotyrosine phosphatases in a glial cell line: TC‐PTP versus PTP‐1B

B. Posner, R. Faure, 1993, Glia.

Angiotensin II binding sites in rat brain.

B. Posner, M. Van Houten, 1981, Science.

Inhibition of the oxidation of leucine by hypoglycin.

B. Posner, M. Raben, 1967, Biochimica et biophysica acta.

Increase in the number of type II insulin-like growth factor receptors during propylthiouracil-induced hyperplasia in the rat thyroid.

C. Polychronakos, B. Posner, B. Patel, 1986, Endocrinology.

Uptake of insulin by plasmalemma and Golgi subcellular fractions of rat liver.

B. Posner, J. Bergeron, A. Verma, 1980, The Journal of biological chemistry.

Insulin binding sites localized to nerve terminals in rat median eminence and arcuate nucleus.

B. Posner, J. Brawer, M. Van Houten, 1980, Science.

Labeling of RNA in the perfused heart: the problem of bacterial contamination.

B. Posner, B. Fanburg, 1969, Biochimica et biophysica acta.

Peptide Hormones and Growth factors: Cellular Signaling Mechanisms

C. Mounier, B. Posner, 2004 .

Compartmentalization of signaling-competent epidermal growth factor receptors in endosomes.

B. Posner, A. Parmar, A. Balbis, 2007, Endocrinology.

The insulin receptor kinase: modulation and therapeutic implications

B. Posner, 2000 .

In vivo uptake of insulin into hepatic Golgi fractions: application of the diaminobenzidine-shift protocol.

B. Posner, J. Bergeron, D. Kay, 1984, Biochemical and biophysical research communications.

Insulin Metabolizing Enzyme Activities in Human Placental Tissue

B. Posner, 1973, Diabetes.

Modulation of Interferon-γ-induced Macrophage Activation by Phosphotyrosine Phosphatases Inhibition

M. Tremblay, B. Posner, M. Olivier, 1998, The Journal of Biological Chemistry.

Regulation of Glycogen Synthase in Rat Hepatocytes

B. Posner, L. Lavoie, J. Bergeron, 1999, The Journal of Biological Chemistry.

Organelle-specific phosphorylation. Identification of unique membrane phosphoproteins of the endoplasmic reticulum and endosomal apparatus.

P. H. Cameron, B. Posner, J. Bergeron, 1993, The Journal of biological chemistry.

Polypeptide hormone binding sites in vivo: initial localization of 125I-labeled insulin to hepatocyte plasmalemma as visualized by electron microscope radioautography.

B. Posner, J. Bergeron, R. Sikstrom, 1977, Proceedings of the National Academy of Sciences of the United States of America.

The role of cell age in the difference in insulin binding between adult and cord erythrocytes.

C. Polychronakos, B. Posner, H. Guyda, 1982, The Journal of clinical endocrinology and metabolism.

Pharmacological doses of insulin equalize insulin receptor phosphotyrosine content but not tyrosine kinase activity in plasmalemmal and endosomal membranes.

B. Posner, A. Bevan, J. Burgess, 1992, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Specific water-soluble binding sites for serum insulin-like peptides in human and animal tissues.

B. Posner, H. Guyda, 1980, Endocrinology.

Concentration of Native Prolactin and Prolactin Binding Sites in Hepatic Subcellular Fractions from Hyperprolactinemic Rats

B. Posner, B. Patel, S. Savoie, 1985, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Binding and uptake of 125I-insulin into rat liver hepatocytes and endothelium. An in vivo radioautographic study

B. Posner, J. Bergeron, A. Hand, 1979, The Journal of cell biology.

Regulation of Histone Deacetylase 4 by Binding of 14-3-3 Proteins

N. Bertos, Xiang-Jiao Yang, D. Bazett-Jones, 2000, Molecular and Cellular Biology.

Cystathionine -synthase: studies on the replacement reaction.

B. Posner, 1972, Biochimica et biophysica acta.

Studies on amino acid levels and transport in the mechanically stressed rat heart.

E. Fallen, B. Posner, L. Mierzwinski, 1973, Journal of molecular and cellular cardiology.