J. Laoukili

发表

FoxM1 is required for execution of the mitotic programme and chromosome stability

Hans Clevers, H. Clevers, R. Medema, 2005, Nature Cell Biology.

Mismatch Repair Status in Patient-Derived Colorectal Cancer Organoids Does Not Affect Intrinsic Tumor Cell Sensitivity to Systemic Therapy

S. Boj, M. Koopman, J. Laoukili, 2021, Cancers.

FoxM1 is degraded at mitotic exit in a Cdh1-dependent manner

R. Medema, J. Laoukili, M. Stahl, 2008, Cell cycle.

Polyglutamylation and polyglycylation of α-and β-tubulins during in vitro ciliated cell differentiation of human respiratory epithelial cells

J. Laoukili, F. Tournier, F. Marano, 2022 .

Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis

Sridhar Ramaswamy, Ben S. Wittner, Fabien Reyal, 2013, Proceedings of the National Academy of Sciences.

KIT promotes tumor stroma formation and counteracts tumor-suppressive TGFβ signaling in colorectal cancer

J. Laoukili, O. Kranenburg, Emre Küçükköse, 2022, Cell Death & Disease.

Distinct and overlapping functions of glutathione peroxidases 1 and 2 in limiting NF-κB-driven inflammation through redox-active mechanisms

O. Werz, J. Laoukili, A. Koeberle, 2019, Redox biology.

Loss of Neuropilin-2 in Murine Mesenchymal-like Colon Cancer Organoids Causes Mesenchymal-to-Epithelial Transition and an Acquired Dependency on Insulin-Receptor Signaling and Autophagy

J. Laoukili, S. Poghosyan, O. Kranenburg, 2022, Cancers.

Downregulation of DNA repair proteins and increased DNA damage in hypoxic colon cancer cells is a therapeutically exploitable vulnerability

I. B. Borel Rinkes, J. Laoukili, O. Kranenburg, 2017, Oncotarget.

Activation of FoxM1 during G2 Requires Cyclin A/Cdk-Dependent Relief of Autorepression by the FoxM1 N-Terminal Domain

S. Mohammed, A. Heck, R. Medema, 2008, Molecular and Cellular Biology.

Activation of FoxM 1 during G 2 Requires Cyclin A / Cdk-Dependent Relief of Autorepression by the FoxM 1 N-Terminal Domain †

S. Mohammed, A. Heck, R. Medema, 2008 .

Protein phosphatase 2A (B55α) prevents premature activation of forkhead transcription factor FoxM1 by antagonizing cyclin A/cyclin-dependent kinase-mediated phosphorylation.

S. Mohammed, R. Medema, J. Laoukili, 2011, The Journal of Biological Chemistry.

BRAFV600E in colorectal cancer reduces sensitivity to oxidative stress and promotes site-specific metastasis by stimulating glutathione synthesis.

I. B. Borel Rinkes, M. Koopman, J. Laoukili, 2022, Cell reports.

Differential expression and cellular distribution of centrin isoforms during human ciliated cell differentiation in vitro.

O. Houcine, M. Bornens, J. Laoukili, 2000, Journal of cell science.

ZNF423 is critically required for retinoic acid-induced differentiation and is a marker of neuroblastoma outcome.

Jan Koster, Michael Hölzel, Rogier Versteeg, 2009, Cancer cell.

Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

I. B. Borel Rinkes, C. Punt, S. Boj, 2022, Journal for ImmunoTherapy of Cancer.

Inhibition of RAF1 kinase activity restores apicobasal polarity and impairs tumour growth in human colorectal cancer

I. B. Borel Rinkes, E. Santo, J. Laoukili, 2016, Gut.

IL-13 alters mucociliary differentiation and ciliary beating of human respiratory epithelial cells.

A Coste, O. Houcine, A. Minty, 2001, The Journal of clinical investigation.

Peritoneal metastases from colorectal cancer belong to Consensus Molecular Subtype 4 and are sensitised to oxaliplatin by inhibiting reducing capacity

J. Koster, J. Laoukili, A. Huitema, 2022, British Journal of Cancer.

Increased Levels of Oxidative Damage in Liver Metastases Compared with Corresponding Primary Colorectal Tumors: Association with Molecular Subtype and Prior Treatment.

P. V. van Diest, I. B. Borel Rinkes, J. Laoukili, 2018, The American journal of pathology.

CD95 ligand induces senescence in mismatch repair-deficient human colon cancer via chronic caspase-mediated induction of DNA damage

J. Laoukili, O. Kranenburg, D. Raats, 2017, Cell Death & Disease.

Polyglutamylation and polyglycylation of alpha- and beta-tubulins during in vitro ciliated cell differentiation of human respiratory epithelial cells.

J. Laoukili, F. Tournier, F. Marano, 1999, Journal of cell science.

FoxM1: at the crossroads of ageing and cancer.

René H Medema, R. Medema, J. Laoukili, 2007, Biochimica et biophysica acta.

Differential anti-tumour effects of MTH1 inhibitors in patient-derived 3D colorectal cancer cultures

I. B. Borel Rinkes, J. Laoukili, O. Kranenburg, 2019, Scientific Reports.

The death receptor CD95 activates the cofilin pathway to stimulate tumour cell invasion

I. B. Borel Rinkes, J. van Rheenen, J. Laoukili, 2011, EMBO reports.

Ciliated differentiation of rabbit tracheal epithelial cells in vitro.

J. Laoukili, M. Gendron, F. Tournier, 1998, European journal of cell biology.

GPx2 suppression of H2O2 stress links the formation of differentiated tumor mass to metastatic capacity in colorectal cancer.

I. B. Borel Rinkes, J. Koster, R. Brigelius-Flohé, 2014, Cancer research.

Long-Lived Human Lymphatic Endothelial Cells to Study Lymphatic Biology and Lymphatic Vessel/Tumor Coculture in a 3D Microfluidic Model.

P. Vulto, J. Laoukili, S. Poghosyan, 2021, ACS biomaterials science & engineering.

The death receptor CD 95 activates the cofilin pathway to stimulate tumor cell invasion

J. Laoukili, O. Kranenburg, J. Rheenen, 2011 .

Co-cultures of colon cancer cells and cancer-associated fibroblasts recapitulate the aggressive features of mesenchymal-like colon cancer

R. Fodde, H. Snippert, J. Laoukili, 2023, Frontiers in Immunology.

Comprehensive evaluation of structural variation detection algorithms for whole genome sequencing

Y. Kamatani, Y. Momozawa, C. Terao, 2019, Genome Biology.

The death receptor CD95 activates the cofilin pathway to stimulate tumour cell invasion

I. B. Borel Rinkes, J. van Rheenen, J. Laoukili, 2011, EMBO reports.

CD95 ligand induces senescence in mismatch repair-deficient human colon cancer via chronic caspase-mediated induction of DNA damage

J. Laoukili, O. Kranenburg, Susanne J van Schelven, 2017, Cell Death & Disease.

BRAF V600E in colorectal cancer reduces sensitivity to oxidative stress and promotes site-speciﬁc metastasis by stimulating glutathione synthesis

M. Koopman, J. Laoukili, O. Kranenburg, 2022 .