D. Pimentel

发表

The FOXO3a Transcription Factor Regulates Cardiac Myocyte Size Downstream of AKT Signaling*

A. Goldberg, I. Shiojima, M. Sandri, 2005, Journal of Biological Chemistry.

S-Glutathiolation of Ras Mediates Redox-sensitive Signaling by Angiotensin II in Vascular Smooth Muscle Cells*[boxs]

D. Pimentel, R. Cohen, T. Adachi, 2004, Journal of Biological Chemistry.

Adventitial delivery of dominant-negative p67phox attenuates neointimal hyperplasia of the rat carotid artery.

D. Pimentel, P. Harding, Jianhua Liu, 2006, American journal of physiology. Heart and circulatory physiology.

Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet‐Induced Metabolic Heart Disease

O. Shirihai, D. Pimentel, E. Miller, 2016, Journal of the American Heart Association.

High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II.

O. Shirihai, D. Pimentel, E. Miller, 2015, Journal of molecular and cellular cardiology.

Statins Inhibit &bgr;-Adrenergic Receptor–Stimulated Apoptosis in Adult Rat Ventricular Myocytes via a Rac1-Dependent Mechanism

Masahiro Ito, D. Pimentel, T. Adachi, 2004, Circulation.

Role of reversible, thioredoxin-sensitive oxidative protein modifications in cardiac myocytes.

D. Pimentel, W. Colucci, D. Siwik, 2006, Antioxidants & redox signaling.

S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide

D. Pimentel, R. Weisbrod, R. Cohen, 2004, Nature Medicine.

Mitochondrial Transporter ATP Binding Cassette Mitochondrial Erythroid Is a Novel Gene Required for Cardiac Recovery After Ischemia/Reperfusion

E. Sahin, O. Shirihai, N. Ruderman, 2011, Circulation.

Adiponectin mediates cardioprotection in oxidative stress-induced cardiac myocyte remodeling.

D. Pimentel, N. Ouchi, R. Shibata, 2011, American journal of physiology. Heart and circulatory physiology.

Role of reactive oxygen species and NAD(P)H oxidase in alpha(1)-adrenoceptor signaling in adult rat cardiac myocytes.

D. Sawyer, D. Pimentel, Krishna Singh, 2002, American journal of physiology. Cell physiology.

Cardiac-Specific Overexpression of Catalase Identifies Hydrogen Peroxide-Dependent and -Independent Phases of Myocardial Remodeling and Prevents the Progression to Overt Heart Failure in G&agr;q-Overexpressing Transgenic Mice

G. Dorn, S. Lancel, D. Pimentel, 2010, Circulation. Heart failure.

Oleate prevents palmitate-induced cytotoxic stress in cardiac myocytes.

N. LeBrasseur, D. Sawyer, N. Ruderman, 2005, Biochemical and biophysical research communications.

Glucose‐6‐Phosphate Dehydrogenase Modulates Cytosolic Redox Status and Contractile Phenotype in Adult Cardiomyocytes

J. Loscalzo, Mohit M. Jain, C. Lim, 2003, Circulation research.

Cardiac Myocyte-specific Ablation of Follistatin-like 3 Attenuates Stress-induced Myocardial Hypertrophy*

Kazuto Nakamura, E. Lara-Pezzi, K. Walsh, 2011, The Journal of Biological Chemistry.

Adiponectin deficiency exacerbates cardiac dysfunction following pressure overload through disruption of an AMPK-dependent angiogenic response.

T. Murohara, K. Walsh, D. Pimentel, 2010, Journal of molecular and cellular cardiology.

Human Amyloidogenic Light Chains Directly Impair Cardiomyocyte Function Through an Increase in Cellular Oxidant Stress

M. Skinner, Mohit M. Jain, R. Liao, 2004, Circulation research.

Cross organelle stress response disruption promotes gentamicin-induced proteotoxicity

Joshua D. Campbell, D. Pimentel, S. Borkan, 2020, Cell Death & Disease.

Follistatin-Like 1 Is an Akt-Regulated Cardioprotective Factor That Is Secreted by the Heart

K. Walsh, Y. Izumiya, Kaori Sato, 2008, Circulation.

Angiotensin II Differentially Regulates Interleukin-1-β-inducible NO Synthase (iNOS) and Vascular Cell Adhesion Molecule-1 (VCAM-1) Expression

D. Pimentel, R. Cohen, X. Hou, 2004, Journal of Biological Chemistry.

Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2–dependent mechanisms

S. Kihara, T. Funahashi, K. Walsh, 2005, Nature Medicine.

A novel tracer for in vivo optical imaging of fatty acid metabolism in the heart and brown adipose tissue

Eric M Gale, D. Pimentel, Howard H. Chen, 2020, Scientific Reports.

Cyclooxygenase‐2 induction by adiponectin is regulated by a sphingosine kinase‐1 dependent mechanism in cardiac myocytes

S. Kihara, K. Walsh, D. Pimentel, 2008, FEBS letters.

Activin A and Follistatin-Like 3 Determine the Susceptibility of Heart to Ischemic Injury

K. Tsuchida, E. Lara-Pezzi, K. Walsh, 2009, Circulation.

H(2)O(2) regulates cardiac myocyte phenotype via concentration-dependent activation of distinct kinase pathways.

D. Sawyer, D. Pimentel, W. Colucci, 2003, Journal of molecular and cellular cardiology.

Regulation of cell physiology and pathology by protein S-glutathionylation: lessons learned from the cardiovascular system.

D. Pimentel, R. Cohen, J. Burgoyne, 2012, Antioxidants & redox signaling.

Strain-stimulated hypertrophy in cardiac myocytes is mediated by reactive oxygen species-dependent Ras S-glutathiolation.

J. Melendez, D. Pimentel, R. Cohen, 2006, Journal of molecular and cellular cardiology.

Redox-Resistant SERCA [Sarco(endo)plasmic Reticulum Calcium ATPase] Attenuates Oxidant-Stimulated Mitochondrial Calcium and Apoptosis in Cardiac Myocytes and Pressure Overload–Induced Myocardial Failure in Mice

D. Pimentel, R. Cohen, M. Panagia, 2020, Circulation.

Redox regulation via glutaredoxin-1 and protein S-glutathionylation.

Jingyan Han, D. Pimentel, M. Bachschmid, 2019, Antioxidants & redox signaling.

Cytosolic H2O2 mediates hypertrophy, apoptosis, and decreased SERCA activity in mice with chronic hemodynamic overload.

D. Pimentel, R. Cohen, W. Colucci, 2014, American journal of physiology. Heart and circulatory physiology.

Increasing mitochondrial ATP synthesis with butyrate normalizes ADP and contractile function in metabolic heart disease

J. Balschi, D. Pimentel, M. Panagia, 2020, NMR in biomedicine.

Decreased ATP production and myocardial contractile reserve in metabolic heart disease

J. Balschi, J. Ingwall, D. Pimentel, 2018, Journal of molecular and cellular cardiology.

&bgr;-Adrenergic Receptor–Stimulated Apoptosis in Cardiac Myocytes Is Mediated by Reactive Oxygen Species/c-Jun NH2-Terminal Kinase–Dependent Activation of the Mitochondrial Pathway

D. Sawyer, D. Pimentel, W. Colucci, 2003, Circulation research.

Differential Effects of Sacubitril/Valsartan on Diastolic Function in Mice With Obesity-Related Metabolic Heart Disease

D. Pimentel, M. Panagia, W. Colucci, 2020, JACC. Basic to translational science.

Energetic Dysfunction Is Mediated by Mitochondrial Reactive Oxygen Species and Precedes Structural Remodeling in Metabolic Heart Disease.

J. Balschi, D. Pimentel, M. Panagia, 2019, Antioxidants & redox signaling.

Oxidative stress in the regulation of myocardial hypertrophy and failure

D. Sawyer, D. Pimentel, W. Colucci, 2005 .

Redox regulation of sirtuin-1 by S-glutathiolation.

David H Perlman, D. Pimentel, R. Cohen, 2010, Antioxidants & redox signaling.

S-Glutathiolation of p21ras by Peroxynitrite Mediates Endothelial Insulin Resistance Caused by Oxidized Low-Density Lipoprotein

D. Pimentel, R. Cohen, X. Hou, 2006, Arteriosclerosis, thrombosis, and vascular biology.

Novel Gene Required for Cardiac Recovery After Ischemia / Reperfusion Mitochondrial Transporter ATP Binding Cassette Mitochondrial Erythroid

E. Sahin, O. Shirihai, N. Ruderman, 2011 .

Cysteine-674 of the Sarco/Endoplasmic Reticulum Calcium ATPase Is Required for the Inhibition of Cell Migration by Nitric Oxide

D. Pimentel, R. Weisbrod, R. Cohen, 2007, Arteriosclerosis, thrombosis, and vascular biology.

A new hypertrophic mechanism of serotonin in cardiac myocytes: receptor‐independent ROS generation

D. Pimentel, M. Murphy, A. Parini, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

&agr;-Adrenergic Receptor–Stimulated Hypertrophy in Adult Rat Ventricular Myocytes Is Mediated via Thioredoxin-1–Sensitive Oxidative Modification of Thiols on Ras

R. Liao, D. Pimentel, R. Cohen, 2005, Circulation.

Oxidative Modification of Thiols on Ras − Mediated via Thioredoxin-1 Stimulated Hypertrophy in Adult Rat Ventricular Myocytes Is −-Adrenergic Receptor

R. Liao, D. Pimentel, R. Cohen, 2005 .

ROS-dependent alpha-adrenergic receptor-stimulated hypertrophy in adult rat cardiac myocytes is mediated by H2O2 or a derivative

D. Pimentel, W. Colucci, D. Siwik, 2003 .

S-Glutathiolation of p 21 ras by Peroxynitrite Mediates Endothelial Insulin Resistance Caused by Oxidized Low-Density Lipoprotein

D. Pimentel, R. Cohen, X. Hou, 2006 .

Abstract 12622: Western Diet for One Month Impairs Myocardial Energetics and Both Systolic and Diastolic Pump Function in the Mouse Heart

J. Balschi, O. Shirihai, D. Pimentel, 2014 .

NADPH oxidase mediates angiotensin II-induced endothelin-1 expression in vascular adventitial fibroblasts.

D. Pimentel, Min-xia Zhu, S. An, 2007, Cardiovascular research.

Temporal control of NF-kappaB activation by ERK differentially regulates interleukin-1beta-induced gene expression.

P. Brecher, D. Pimentel, R. Cohen, 2004, Journal of Biological Chemistry.

High glucose oxidizes SERCA cysteine-674 and prevents inhibition by nitric oxide of smooth muscle cell migration.

D. Pimentel, R. Cohen, T. Adachi, 2008, Journal of molecular and cellular cardiology.

Norepinephrine stimulates apoptosis in adult rat ventricular myocytes by activation of the beta-adrenergic pathway.

D. Pimentel, W. Colucci, K. Singh, 1998, Circulation.

Cardiovascular redox and ox stress proteomics.

D. Pimentel, R. Cohen, M. McComb, 2012, Antioxidants & redox signaling.

Role of reactive oxygen species and NAD(P)H oxidase in alpha(1)-adrenoceptor signaling in adult rat cardiac myocytes.

D. Sawyer, D. Pimentel, W. Colucci, 2002, American journal of physiology. Cell physiology.

Reactive Oxygen Species Mediate Amplitude-Dependent Hypertrophic and Apoptotic Responses to Mechanical Stretch in Cardiac Myocytes

D. Sawyer, D. Pimentel, W. Colucci, 2001, Circulation research.

Association of mitochondrial antioxidant enzymes with mitochondrial DNA as integral nucleoid constituents

D. Pimentel, A. Bürkle, V. Ullrich, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Activation of Thromboxane Receptor Upregulates Interleukin (IL)-1β–Induced VCAM-1 Expression Through JNK Signaling

D. Pimentel, R. Cohen, B. Jiang, 2007, Arteriosclerosis, thrombosis, and vascular biology.

Expression Through JNK Signaling Induced VCAM-1 − β Activation of Thromboxane Receptor Upregulates Interleukin ( IL )-1

D. Pimentel, R. Cohen, B. Jiang, 2007 .

Production of adeno-associated virus vectors for in vitro and in vivo applications

D. Pimentel, T. Adachi, Y. Ido, 2019, Scientific Reports.

Cardiac-specific Deletion of LKB1 Leads to Hypertrophy and Dysfunction

J. Dyck, R. Shaw, K. Walsh, 2009, The Journal of Biological Chemistry.

Genetically Targeted Fluorescent Probes Reveal Dynamic Calcium Responses to Adrenergic Signaling in Multiple Cardiomyocyte Compartments.

D. Pimentel, M. Kirber, W. Colucci, 2019, The international journal of biochemistry & cell biology.

Temporal Control of NF-κB Activation by ERK Differentially Regulates Interleukin-1β-induced Gene Expression*

P. Brecher, D. Pimentel, R. Cohen, 2004, Journal of Biological Chemistry.

Adiponectin-mediated modulation of hypertrophic signals in the heart

S. Kihara, T. Funahashi, I. Shiojima, 2004, Nature Medicine.

Fenofibrate inhibits aldosterone-induced apoptosis in adult rat ventricular myocytes via stress-activated kinase-dependent mechanisms.

S. Lancel, D. Pimentel, F. Sam, 2009, American journal of physiology. Heart and circulatory physiology.

Oxidized GAPDH transfers S-glutathionylation to a nuclear protein Sirtuin-1 leading to apoptosis.

D. Pimentel, R. Weisbrod, N. Hamburg, 2021, Free radical biology & medicine.

Endomembrane H-Ras Controls Vascular Endothelial Growth Factor-induced Nitric-oxide Synthase-mediated Endothelial Cell Migration*

Joseph R. Burgoyne, D. Pimentel, R. Cohen, 2013, The Journal of Biological Chemistry.

Endomembrane HRas controls vascular endothelial growth factor-induced nitric oxide synthase-mediated endothelial cell migration.

Joseph R. Burgoyne, D. Pimentel, X. Hou, 2013 .

Cardiac myocyte follistatin-like 1 functions to attenuate hypertrophy following pressure overload

Kazuto Nakamura, T. Murohara, K. Walsh, 2011, Proceedings of the National Academy of Sciences.

Role of oxidative stress in myocardial hypertrophy and failure.

D. Sawyer, D. Pimentel, W. Colucci, 2002, Journal of molecular and cellular cardiology.

Adiponectin Modulates Oxidative Stress-Induced Autophagy in Cardiomyocytes

D. Pimentel, N. Ouchi, F. Sam, 2013, PloS one.

Effects of Sodium‐Glucose Linked Transporter 2 Inhibition With Ertugliflozin on Mitochondrial Function, Energetics, and Metabolic Gene Expression in the Presence and Absence of Diabetes Mellitus in Mice

D. Pimentel, M. Panagia, W. Colucci, 2021, Journal of the American Heart Association.

A Redox-resistant Sirtuin-1 Mutant Protects against Hepatic Metabolic and Oxidant Stress*

Jingyan Han, D. Pimentel, R. Cohen, 2014, The Journal of Biological Chemistry.

Superoxide anion mediates norepinephrine-induced hypertrophy, but not contractility, in adult rat ventricular myocytes

D. Sawyer, D. Pimentel, W. Colucci, 1998 .

Role of Glutaredoxin-1 and Glutathionylation in Cardiovascular Diseases

D. Pimentel, N. Hamburg, Y. Tsukahara, 2020, International journal of molecular sciences.

A novel mutant cardiac troponin C disrupts molecular motions critical for calcium binding affinity and cardiomyocyte contractility.

Haijun Yang, Catherine E Costello, Shuanghong Huo, 2008, Biophysical journal.

L-Homocysteine and L-homocystine stereospecifically induce endothelial nitric oxide synthase-dependent lipid peroxidation in endothelial cells.

J. Loscalzo, J. Keaney, D. Pimentel, 2004, Free radical biology & medicine.

SGLT2 inhibitor ertugliflozin decreases elevated intracellular sodium, and improves energetics and contractile function in diabetic cardiomyopathy

J. Balschi, D. Pimentel, M. Panagia, 2023, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Palmitate alters neuregulin signaling and biology in cardiac myocytes.

N. LeBrasseur, D. Sawyer, D. Pimentel, 2009, Biochemical and biophysical research communications.

- Adrenergic Pathway β the Norepinephrine Stimulates Apoptosis in Adult Rat Ventricular Myocytes by Activation of

D. Pimentel, W. Colucci, C. Communal, 1998 .

Activation of thromboxane receptor modulates interleukin-1β-induced monocyte adhesion--a novel role of Nox1.

R. Brandes, D. Pimentel, R. Cohen, 2012, Free radical biology & medicine.

A novel tracer for in vivo optical imaging of fatty acid metabolism in the heart and brown adipose tissue

D. Pimentel, Howard H. Chen, D. Sosnovik, 2020, Scientific Reports.

Mitochondrial Transporter ATP Binding Cassette Mitochondrial Erythroid Is a Novel Gene Required for Cardiac Recovery After Ischemia/Reperfusion

O. Shirihai, N. Ruderman, X. J. Xu, 2011, Circulation.

Cyclooxygenase‐2 induction by adiponectin is regulated by a sphingosine kinase‐1 dependent mechanism in cardiac myocytes

S. Kihara, K. Walsh, D. Pimentel, 2008, FEBS Letters.

Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet‐Induced Metabolic Heart Disease

O. Shirihai, D. Pimentel, E. Miller, 2016, Journal of the American Heart Association.

High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II.

O. Shirihai, D. Pimentel, E. Miller, 2015, Journal of molecular and cellular cardiology.

Hemodynamic testing to guide vasodilator therapy in cardiac amyloidosis.

D. Pimentel, O. Siddiqi, I. Luptak, 2023, Journal of cardiology cases.