G. Johnson

发表

14-3-3ζ does not increase GSK3β-mediated tau phosphorylation in cell culture models

T. Matthews, G. Johnson, 2005, Neuroscience Letters.

E. Masliah, G. Johnson, Ameneh Zare-Shahabadi, 2015, Reviews in the neurosciences.

Tau phosphorylation in neuronal cell function and dysfunction

G. Johnson, W. Stoothoff, William H. Stoothoff, 2004, Journal of Cell Science.

Primed phosphorylation of tau at Thr231 by glycogen synthase kinase 3β (GSK3β) plays a critical role in regulating tau's ability to bind and stabilize microtubules

J. Cho, G. Johnson, 2003, Journal of neurochemistry.

Histone deacetylase 6 interacts with the microtubule‐associated protein tau

P. Dolan, G. Johnson, H. Ding, 2008, Journal of neurochemistry.

The FASEB Journal • Research Communication Transglutaminase 2 protects against ischemic insult, interacts with HIF1�, and attenuates HIF1 signaling

G. Johnson, A. Filiano, C. Bailey, 2022 .

Guidelines for the use and interpretation of assays for monitoring autophagy

Robert Clarke, Hong Jiang, Hiroyuki Ishida, 2012 .

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

Mechanisms of tau and Aβ-induced excitotoxicity

J. DiMaio, G. Johnson, B. Nilsson, 2016, Brain Research.

Transglutaminase 2 facilitates or ameliorates HIF signaling and ischemic cell death depending on its conformation and localization.

G. Johnson, R. Blouin, Soner Gundemir, 2013, Biochimica et biophysica acta.

Transglutaminase 2: Friend or foe? The discordant role in neurons and astrocytes

G. Johnson, Breandan Quinn, Laura Yunes-Medina, 2018, Journal of neuroscience research.

Glycogen Synthase Kinase 3β Is Tyrosine Phosphorylated by PYK2

G. Johnson, W. Xiong, W. Xiong, 2001 .

Tau phosphorylation: physiological and pathological consequences.

G. Johnson, W. Stoothoff, Gail V W Johnson, 2005, Biochimica et biophysica acta.

Split GFP complementation assay for quantitative measurement of tau aggregation in situ.

G. Waldo, G. Johnson, W. Chun, 2011, Methods in molecular biology.

Phosphorylation of PPP(S/T)P motif of the free LRP6 intracellular domain is not required to activate the Wnt/β‐catenin pathway and attenuate GSK3β activity

G. Johnson, Kaihong Mi, Brandon R. Beagle, 2009, Journal of cellular biochemistry.

Insulin Transiently Increases Tau Phosphorylation

R. Jope, G. Johnson, M. Lesort, 1999, Journal of neurochemistry.

Tau protein in normal and Alzheimer's disease brain: an update.

G. Johnson, J. A. Hartigan, 1999, Journal of Alzheimer's disease : JAD.

Mutant (R406W) Human Tau Is Hyperphosphorylated and Does Not Efficiently Bind Microtubules in a Neuronal Cortical Cell Model*

G. Johnson, P. Krishnamurthy, 2004, Journal of Biological Chemistry.

Proteolysis of tau by calpain.

R. Jope, G. Johnson, L. Binder, 1989, Biochemical and biophysical research communications.

Depletion of astrocytic transglutaminase 2 improves injury outcomes

G. Johnson, C. Pröschel, Julianne Feola, 2018, Molecular and Cellular Neuroscience.

Seizure‐Induced Protein Tyrosine Phosphorylation in Rat Brain Regions

R. Jope, G. Johnson, M. S. Baird, 1991, Epilepsia.

Decreases in valosin‐containing protein result in increased levels of tau phosphorylated at Ser262/356

P. Dolan, Woong Y. Hwang, G. Johnson, 2011, FEBS letters.

Complete transglutaminase 2 ablation results in reduced stroke volumes and astrocytes that exhibit increased survival in response to ischemia

G. Johnson, G. Colak, 2012, Neurobiology of Disease.

Cytosolic Guanine Nucledotide Binding Deficient Form of Transglutaminase 2 (R580a) Potentiates Cell Death in Oxygen Glucose Deprivation

G. Johnson, G. Colak, J. Keillor, 2011, PloS one.

A Caspase Cleaved Form of Tau Is Preferentially Degraded through the Autophagy Pathway*

P. Dolan, G. Johnson, 2010, The Journal of Biological Chemistry.

Intracellular Localization and Conformational State of Transglutaminase 2: Implications for Cell Death

G. Johnson, Soner Gundemir, 2009, PloS one.

FRAT-2 Preferentially Increases Glycogen Synthase Kinase 3β-mediated Phosphorylation of Primed Sites, Which Results in Enhanced Tau Phosphorylation*

J. Cho, G. Johnson, W. Stoothoff, 2005, Journal of Biological Chemistry.

The role of BAG3 in health and disease: A “Magic BAG of Tricks”

G. Johnson, Shon A Koren, Heng Lin, 2021, Journal of cellular biochemistry.

Tau protein is phosphorylated by cyclic AMP-dependent protein kinase and calcium/calmodulin-dependent protein kinase II within its microtubule-binding domains at Ser-262 and Ser-356.

M. Goedert, G. Johnson, R. Jakes, 1996, The Biochemical journal.

BAG3 and SYNPO (synaptopodin) facilitate phospho-MAPT/Tau degradation via autophagy in neuronal processes

G. Johnson, J. Höhfeld, Maoping Tang, 2019, Autophagy.

Cholinergic- and stress-induced signaling activities in cells overexpressing wild-type and mutant presenilin-1

R. Jope, G. Johnson, G. Bijur, 2001, Brain Research.

Oxidative Stress Inhibits Calpain Activity in Situ *

G. Johnson, R. Guttmann, Rodney P. Guttmann, 1998, The Journal of Biological Chemistry.

‘Oxidation Inhibits Substrate Proteolysis by Calpain I but Not Autolysis*

P. D. Bell, G. Johnson, J. Elce, 1997, The Journal of Biological Chemistry.

Transglutaminase 2 protects against ischemic stroke

P. Dolan, G. Johnson, A. Filiano, 2010, Neurobiology of Disease.

The Microtubule Binding of Tau and High Molecular Weight Tau in Apoptotic PC12 Cells Is Impaired because of Altered Phosphorylation*

G. Johnson, P. K. Davis, Penny K. Davis, 1999, The Journal of Biological Chemistry.

Inhibition or ablation of transglutaminase 2 impairs astrocyte migration.

G. Johnson, J. Keillor, A. Monteagudo, 2017, Biochemical and biophysical research communications.

Tissue transglutaminase overexpression in the brain potentiates calcium‐induced hippocampal damage

K. Roth, G. Johnson, J. Tucholski, 2006, Journal of neurochemistry.

Phosphorylated tau potentiates Aβ-induced mitochondrial damage in mature neurons

N. Inestrosa, G. Johnson, R. Quintanilla, 2014, Neurobiology of Disease.

New application of β‐galactosidase complementation to monitor tau self‐association

G. Johnson, H. Ding, 2008, Journal of neurochemistry.

Immortalized cortical neurons expressing caspase-cleaved tau are sensitized to endoplasmic reticulum stress induced cell death

G. Johnson, R. Quintanilla, H. Ding, 2008, Brain Research.

Tau phosphorylation and proteolysis: insights and perspectives.

G. Johnson, 2006, Journal of Alzheimer's disease : JAD.

Alterations of choline acetyltransferase, phosphoinositide hydrolysis, and cytoskeletal proteins in rat brain in response to colchicine administration

R. Jope, G. Johnson, K. Kolasa, 1992, Experimental Brain Research.

p38 Kinase Is Activated in the Alzheimer's Disease Brain

W. Markesbery, J. Geddes, Nai-Ying Zheng, 1999, Journal of neurochemistry.

Tau Is Modified by Tissue Transglutaminase In Situ: Possible Functional and Metabolic Effects of Polyamination

J. Kuret, G. Johnson, J. Tucholski, 1999, Journal of neurochemistry.

Monoclonal antibody Alz‐50 reacts with bovine and human serum albumin

G. Johnson, P. K. Davis, 1994, Journal of neuroscience research.

Metal (Fe3+) affinity chromatography: differential adsorption of tau phosphoproteins

G. Johnson, A. C. Erickson, 1993, Journal of Neuroscience Methods.

Tau phosphorylation during apoptosis of human SH-SY5Y neuroblastoma cells

G. Johnson, P. Mookherjee, 2001, Brain Research.

Transglutaminase activity is increased in Alzheimer's disease brain

R. Powers, G. Johnson, Michael L. Miller, 1997, Brain Research.

τ Self‐Association: Stabilization with a Chemical Cross‐Linker and Modulation by Phosphorylation and Oxidation State

G. Johnson, R. Guttmann, A. C. Erickson, 1995, Journal of neurochemistry.

Transglutaminase Catalyzes the Formation of Sodium Dodecyl Sulfate‐Insoluble, Alz‐50‐Reactive Polymers of τ

S. Dudek, G. Johnson, 1993, Journal of neurochemistry.

BAG3 Regulation of RAB35 Mediates the Endosomal Sorting Complexes Required for Transport/Endolysosome Pathway and Tau Clearance

G. Johnson, Maoping Tang, Shon A Koren, 2021, Biological Psychiatry.

BAG 3 regulation of Rab 35 mediates the ESCRT / endolysosome pathway and tau clearance

G. Johnson, Maoping Tang, Changyi Ji, 2021 .

Transglutaminase facilitates the formation of polymers of the β-amyloid peptide

S. Dudek, G. Johnson, 1994, Brain Research.

Compromised mitochondrial function results in dephosphorylation of tau through a calcium-dependent process in rat brain cerebral cortical slices

G. Johnson, S. Norman, 1994, Neurochemical Research.

Tau protein in normal and Alzheimer's disease brain.

G. Johnson, S. Jenkins, 1999, Journal of Alzheimer's disease : JAD.

The role of transglutaminase 2 in mediating glial cell function and pathophysiology in the central nervous system.

G. Johnson, Anson Cheng, Jacob Rudlong, 2019, Analytical biochemistry.

Nerve Growth Factor Protects PC12 Cells Against Peroxynitrite‐Induced Apoptosis via a Mechanism Dependent on Phosphatidylinositol 3‐Kinase

L. Barbeito, G. Johnson, J. Beckman, 1997, Journal of neurochemistry.

Distinct Nuclear Localization and Activity of Tissue Transglutaminase*

G. Johnson, M. Lesort, J. Zhang, 1998, The Journal of Biological Chemistry.

Tau and HMW tau phosphorylation and compartmentalization in apoptotic neuronal PC12 cells

G. Johnson, S. B. Shelton, 2001, Journal of neuroscience research.

Casein kinase II preferentially phosphorylates human tau isoforms containing an amino-terminal insert. Identification of threonine 39 as the primary phosphate acceptor.

C. W. Scott, G. Johnson, R. C. Spreen, 1994, The Journal of biological chemistry.

The τ Protein in Human Cerebrospinal Fluid in Alzheimer's Disease Consists of Proteolytically Derived Fragments

Douglas Galasko, R. Motter, G. Johnson, 1997, Journal of neurochemistry.

Caspase-cleaved Tau Expression Induces Mitochondrial Dysfunction in Immortalized Cortical Neurons

P. Dolan, G. Johnson, R. Quintanilla, 2009, The Journal of Biological Chemistry.

Immunoblot analysis reveals that isopeptide antibodies do not specifically recognize the ε-(γ-glutamyl)lysine bonds formed by transglutaminase activity

G. Johnson, Reginald LeShoure, 2004, Journal of Neuroscience Methods.

Transient osmotic stress facilitates mutant huntingtin aggregation

G. Johnson, W. Chun, Matthew Lee, 2002, Neuroreport.

Transient oxidative stress in SH‐SY5Y human neuroblastoma cells results in caspase dependent and independent cell death and tau proteolysis

J. L. Mays, G. Johnson, G. Bijur, 2000 .

Tau Is Hyperphosphorylated at Multiple Sites in Mouse Brain In Vivo After Streptozotocin-Induced Insulin Deficiency

A. Zmijewska, R. Jope, G. Johnson, 2006, Diabetes.

Transglutaminase 2 and its role in pulmonary fibrosis.

G. Johnson, T. Thatcher, P. Sime, 2011, American journal of respiratory and critical care medicine.

Glycogen synthase kinase 3beta is tyrosine phosphorylated by PYK2.

G. Johnson, W. Xiong, J. A. Hartigan, 2001, Biochemical and biophysical research communications.

Phosphorylation of rat brain cytoskeletal proteins is increased after orally administered aluminum

R. Jope, G. Johnson, 1988, Brain Research.

The effects of aluminum on agonist-induced alterations in cyclic AMP and cyclic GMP concentrations in rat brain regions in vivo.

G. Johnson, 1988, Toxicology.

Aluminum alters cyclic AMP and cyclic GMP levels but not presynaptic cholinergic markers in rat brain in vivo

R. Jope, G. Johnson, 1987, Brain Research.

Aluminum increases cyclic AMP in rat cerebral cortex in vivo.

R. Jope, G. Johnson, 1986, Life sciences.

Cyclin‐dependent kinase‐5 in neurodegeneration

G. Johnson, S. B. Shelton, 2004, Journal of neurochemistry.

Sulforaphane induces autophagy through ERK activation in neuronal cells

G. Johnson, Sunhyo Kim, Sang-Moon Yun, 2014, FEBS letters.

Regulated proteolytic processing of LRP6 results in release of its intracellular domain

G. Johnson, Kaihong Mi, 2007, Journal of neurochemistry.

Increased aerobic glucose oxidation by cAMP in cultured regenerated skeletal myotubes.

G. Johnson, C. Hartzell, N. Schroedl, 1986, The American journal of physiology.

Hyperosmotic stress‐induced apoptosis and tau phosphorylation in human neuroblastoma cells

G. Johnson, W. Stoothoff, William H. Stoothoff, 2001, Journal of neuroscience research.

Selective Disruption of Drp1-Independent Mitophagy and Mitolysosome Trafficking by an Alzheimer's Disease Relevant Tau Modification in a Novel C. elegans Model.

G. Johnson, K. Nehrke, D. King, 2021, Genetics.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

Endostatin and transglutaminase 2 are involved in fibrosis of the aging kidney.

M. Goligorsky, T. Pihlajaniemi, G. Johnson, 2016, Kidney international.

BAG3 Regulation of RAB35 Mediates the Endosomal Sorting Complexes Required for Transport/Endolysosome Pathway and Tau Clearance

G. Johnson, Maoping Tang, Shon A Koren, 2021, Biological Psychiatry.

Depletion of transglutaminase 2 in neurons alters expression of extracellular matrix and signal transduction genes and compromises cell viability

G. Johnson, Laura Yunes-Medina, Yan Nuzbrokh, 2018, Molecular and Cellular Neuroscience.

Presenilin 1 Regulates Membrane Homeostatic Pathways that are Dysregulated in Alzheimer's Disease.

G. Johnson, Carol A. Deaton, 2020, Journal of Alzheimer's disease : JAD.

Small-Scale Variation in Soil Test Phosphorus and Bermudagrass Yield

R. W. Whitney, W. Raun, J. Solie, 1997 .

A T231E Mutant that Mimics Pathologic Phosphorylation of Tau in Alzheimer’s disease Causes Activation of the Mitochondrial Unfolded Protein Response in C. elegans touch neurons

G. Johnson, K. Nehrke, Sarah Fischer, 2020, microPublication biology.

Transglutaminase and Polyamination of Tubulin: Posttranslational Modification for Stabilizing Axonal Microtubules

N. Chabot, G. Johnson, D. Helseth, 2013, Neuron.

Tissue transglutaminase is essential for neurite outgrowth in human neuroblastoma SH-SY5Y cells

G. Johnson, J. Tucholski, M. Lesort, 2001, Neuroscience.

Glycogen Synthase Kinase 3 (cid:1) Induces Caspase-cleaved Tau Aggregation in Situ *

J. Cho, G. Johnson, 2022 .

Tissue transglutaminase differentially modulates apoptosis in a stimuli‐dependent manner

G. Johnson, J. Tucholski, 2002, Journal of neurochemistry.

Glycogen synthase kinase-3beta, beta-catenin, and tau in postmortem bipolar brain.

R. Jope, G. Johnson, C. Stockmeier, 1999, Journal of neural transmission.

Glycogen synthase kinase-3β, β-catenin, and tau in postmortem bipolar brain

R. Jope, G. Johnson, C. Stockmeier, 1999, Journal of Neural Transmission.

Vena cava and aortic smooth muscle cells express transglutaminases 1 and 4 in addition to transglutaminase 2.

G. Johnson, K. Hitomi, S. Watts, 2012, American journal of physiology. Heart and circulatory physiology.

Phosphorylation by cAMP-dependent protein kinase inhibits the degradation of tau by calpain.

G. Johnson, J. Litersky, 1992, The Journal of biological chemistry.

Tissue Transglutaminase Is an In Situ Substrate of Calpain: Regulation of Activity

G. Johnson, R. Guttmann, J. Zhang, 1998, Journal of neurochemistry.

Calcineurin inhibition prevents calpain‐mediated proteolysis of tau in differentiated PC12 cells

G. Johnson, H. Xie, 1998, Journal of neuroscience research.

Differential phosphorylation of tau by cyclic AMP-dependent protein kinase and Ca2+/calmodulin-dependent protein kinase II: metabolic and functional consequences.

G. Johnson, 1992, Journal of neurochemistry.

Tissue transglutaminase triggers oligomerization and activation of dual leucine zipper-bearing kinase in calphostin C-treated cells to facilitate apoptosis

C. Rancourt, G. Johnson, K. Robitaille, 2004, Cell Death and Differentiation.

A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology

M. Vendruscolo, E. Huey, A. Possenti, 2018, Nature Neuroscience.

Commentary: BAG3 as a Mediator of Endosome Function and Tau Clearance

G. Johnson, Heng Lin, Carol A. Deaton, 2022, Neuroscience.

Proteolysis of Microtubule‐Associated Protein 2 and Tubulin by Cathepsin D

G. Johnson, J. Whitaker, J. Litersky, 1991, Journal of neurochemistry.

Choline Uptake, Acetylcholine Synthesis and Release, and Halothane Effects in Synaptosomes

G. Johnson, C. Hartzell, 1985, Anesthesia and analgesia.

Subcellular localization patterns of transglutaminase 2 in astrocytes and neurons are differentially altered by hypoxia

G. Johnson, Julianne Feola, Laura Yunes-Medina, 2017, Neuroreport.

Transglutaminase 2 modulation of NF-κB signaling in astrocytes is independent of its ability to mediate astrocytic viability in ischemic injury

G. Johnson, Julianne Feola, J. Keillor, 2017, Brain Research.

Transglutaminase 2: a molecular Swiss army knife.

G. Johnson, J. Tucholski, Soner Gundemir, 2012, Biochimica et biophysica acta.

BAG3 and SYNPO (synaptopodin) facilitate phospho-MAPT/Tau degradation via autophagy in neuronal processes

G. Johnson, J. Höhfeld, Maoping Tang, 2019, bioRxiv.

Microtubule/MAP‐Affinity Regulating Kinase (MARK) Is Activated by Phenylarsine Oxide In Situ and Phosphorylates Tau Within Its Microtubule‐Binding Domain

G. Johnson, S. Jenkins, 2000, Journal of neurochemistry.

Modulation of Tau Phosphorylation Within Its Microtubule‐Binding Domain by Cellular Thiols

G. Johnson, S. Jenkins, 1999, Journal of neurochemistry.

Understanding the hyperphosphorylation of tau in Alzheimer's disease: Importance of examining site-specific phosphorylation in non-disease systems

G. Johnson, J. A. Greenwood, 1995, Neurobiology of Aging.

Three different human tau isoforms and rat neurofilament light, middle and heavy chain proteins are cellular substrates for transglutaminase

G. Johnson, A. Grierson, Christopher C. J. Miller, 2001, Neuroscience Letters.

Rapid, single-step procedure for the identification of transglutaminase-mediated isopeptide crosslinks in amino acid digests.

M. Miller, G. Johnson, Michael L. Miller, 1999, Journal of chromatography. B, Biomedical sciences and applications.

Neurotoxic effects of dietary aluminium.

R. Jope, G. Johnson, 1992, Ciba Foundation symposium.

Developmental regulation of tissue transglutaminase in the mouse forebrain

G. Johnson, C. Bailey, 2004, Journal of neurochemistry.

Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner

I. Rahman, G. Johnson, Maoping Tang, 2018, Neurobiology of Aging.

Assessing the degradation of tau in primary neurons: The role of autophagy.

G. Johnson, Maoping Tang, Changyi Ji, 2017, Methods in cell biology.

Modulation of carbachol-stimulated inositol phospholipid hydrolysis in rat cerebral cortex

R. Jope, G. Johnson, T. Casebolt, 1987, Neurochemical Research.

Transglutaminase facilitates the formation of polymers of the beta-amyloid peptide.

S. Dudek, G. Johnson, 1994, Brain research.

Glycogen Synthase Kinase 3β Phosphorylates Tau at Both Primed and Unprimed Sites

J. Cho, G. Johnson, 2003, The Journal of Biological Chemistry.

Aluminum impairs glucose utilization and cholinergic activity in rat brain in vitro.

R. Jope, G. Johnson, 1986, Toxicology.

The role of microtubule‐associated protein 2 (MAP‐2) in neuronal growth, plasticity, and degeneration

R. Jope, G. Johnson, 1992, Journal of neuroscience research.

Degradation of Microtubule‐Associated Protein 2 and Brain Spectrin by Calpain: A Comparative Study

R. Jope, G. Johnson, J. Litersky, 1991, Journal of neurochemistry.

Hippocampal microtubule-associated protein-2 alterations with contextual memory 1 Published on the World Wide Web on 28 January 1999. 1

N. Woolf, G. Johnson, M. Zinnerman, 1999, Brain Research.

Detection of Phosphorylated Ser262 in Fetal Tau, Adult Tau, and Paired Helical Filament Tau (*)

J. Trojanowski, V. Lee, R. Barbour, 1995, The Journal of Biological Chemistry.

The Microtubule-associated Protein Tau Is Extensively Modified with O-linked N-acetylglucosamine*

G. Hart, G. Johnson, D. L. Dong, 1996, The Journal of Biological Chemistry.

Oral aluminum alters in vitro protein phosphorylation and kinase activities in rat brain

Richard S. Jope, K. Cogdill, R. Jope, 1990, Neurobiology of Aging.

Transient Increases in Intracellular Calcium Result in Prolonged Site-selective Increases in Tau Phosphorylation through a Glycogen Synthase Kinase 3β-dependent Pathway*

G. Johnson, J. A. Hartigan, 1999, The Journal of Biological Chemistry.

Phosphorylation Modulates Calpain‐Mediated Proteolysis and Calmodulin Binding of the 200‐kDa and 160‐kDa Neurofilament Proteins

J. Troncoso, G. Johnson, J. A. Greenwood, 1993, Journal of neurochemistry.

Aluminum Increases Agonist‐Stimulated Cyclic AMP Production in Rat Cerebral Cortical Slices

Xiaohua Li, R. Jope, G. Johnson, 1989, Journal of neurochemistry.

Measurement of calpain activity in vitro and in situ using a fluorescent compound and tau as substrates.

G. Johnson, R. Guttmann, 2000, Methods in molecular biology.

Calpains: Intact and active?

G. Johnson, R. Guttmann, 1997, BioEssays : news and reviews in molecular, cellular and developmental biology.

Mitochondrial Respiration and ATP Production Are Significantly Impaired in Striatal Cells Expressing Mutant Huntingtin*

G. Johnson, T. Milaković, 2005, Journal of Biological Chemistry.

All-optical spatiotemporal mapping of ROS dynamics across mitochondrial microdomains in situ

G. Johnson, Alicia Y. Wei, Annika Müller-Eigner, 2023, bioRxiv.

Localization and in situ phosphorylation state of nuclear tau.

G. Johnson, J. A. Greenwood, Gail V. W. Johnson, 1995, Experimental cell research.

Modulation of the in Situ Activity of Tissue Transglutaminase by Calcium and GTP*

G. Johnson, J Zhang, M Lesort, 1998, The Journal of Biological Chemistry.

Altered protein kinase C activation of Na+/Ca2+exchange in mesangial cells from salt-sensitive rats.

G. Johnson, M. T. Unlap, P. Bell, 1999, American journal of physiology. Renal physiology.

The complex role of transglutaminase 2 in glioblastoma proliferation

G. Johnson, Soner Gundemir, J. Keillor, 2016, Neuro-oncology.

The complex role of transglutaminase 2 in glioblastoma proliferation.

G. Johnson, Soner Gundemir, J. Keillor, 2016, Neuro-oncology.

Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease

G. Johnson, R. Quintanilla, Rodrigo A. Quintanilla, 2009, Brain Research Bulletin.

Mutant Huntingtin Expression Induces Mitochondrial Calcium Handling Defects in Clonal Striatal Cells

G. Johnson, R. Quintanilla, T. Milaković, 2006, Journal of Biological Chemistry.

Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release.

M. MacDonald, P. Detloff, G. Johnson, 2004, Human molecular genetics.

Mechanoenzymatic Cleavage of the Ultralarge Vascular Protein von Willebrand Factor

Steven Finkbeiner, Michael E. Greenberg, Marcy E. MacDonald, 2009 .

The regulatory role of calmodulin in the proteolysis of individual neurofilament proteins by calpain

J. Troncoso, G. Johnson, J. A. Greenwood, 1991, Neurochemical Research.

Ceramide Selectively Decreases Tau Levels in Differentiated PC12 Cells Through Modulation of Calpain I

G. Johnson, Han-qing Xie, 1997, Journal of neurochemistry.

Tauopathy-associated tau modifications selectively impact neurodegeneration and mitophagy in a novel C. elegans single-copy transgenic model

G. Johnson, K. Nehrke, Sarah Fischer, 2020, Molecular neurodegeneration.

The glamour and gloom of glycogen synthase kinase-3.

R. Jope, G. Johnson, Richard S Jope, 2004, Trends in biochemical sciences.

The interrelationship between mitochondrial dysfunction and transcriptional dysregulation in Huntington disease

G. Johnson, Youngnam N. Jin, 2010, Journal of bioenergetics and biomembranes.

Transglutaminase regulation of cell function.

R. Eckert, G. Johnson, K. Mehta, 2014, Physiological reviews.

Enhancement of peroxynitrite-induced apoptosis in PC12 cells by fibroblast growth factor-1 and nerve growth factor requires p21Ras activation and is suppressed by Bcl-2.

D. Bredesen, J. Thompson, G. Johnson, 1998, Archives of biochemistry and biophysics.

Stimulation of Tau Degradation

G. Johnson, R. Quintanilla, Adrianne S. Chesser, 2016 .

The toxicity of tau in Alzheimer disease: turnover, targets and potential therapeutics

P. Dolan, G. Johnson, Alisa Vitkus, 2011, Journal of cellular and molecular medicine.

Tissue transglutaminase: a possible role in neurodegenerative diseases

G. Johnson, J. Tucholski, M. Lesort, 2000, Progress in Neurobiology.

Axin negatively affects tau phosphorylation by glycogen synthase kinase 3β

Sheng-Cai Lin, G. Johnson, W. Stoothoff, 2002, Journal of neurochemistry.

Intracellular Localization and Activity State of Tissue Transglutaminase Differentially Impacts Cell Death*

G. Johnson, E. McCoy, J. Tucholski, 2004, Journal of Biological Chemistry.

Metabolic State Determines Sensitivity to Cellular Stress in Huntington Disease: Normalization by Activation of PPARγ

Woong Y. Hwang, G. Johnson, Youngnam N. Jin, 2012, PloS one.

AES/GRG5: More Than Just a Dominant-Negative TLE/GRG Family Member

G. Johnson, Brandon R. Beagle, 2010, Developmental dynamics : an official publication of the American Association of Anatomists.

Cyclin‐dependent kinase‐5 in neurodegeneration

G. Johnson, S. B. Shelton, 2004 .

BAG3 facilitates the clearance of endogenous tau in primary neurons

Corey O. Brizzee, G. Johnson, Zhinian Lei, 2015, Neurobiology of Aging.

Transglutaminase 2 in neurodegenerative disorders.

G. Johnson, Qingmin Ruan, 2007, Frontiers in bioscience : a journal and virtual library.

Transglutaminases in neurodegenerative disorders.

G. Johnson, C. Bailey, J. Tucholski, 2005, Progress in experimental tumor research.

Activation of glycogen synthase kinase 3beta promotes the intermolecular association of tau. The use of fluorescence resonance energy transfer microscopy.

G. Johnson, W. Chun, 2007, The Journal of biological chemistry.

Mitochondrial‐targeted active Akt protects SH‐SY5Y neuroblastoma cells from staurosporine‐induced apoptotic cell death

M. Roh, A. Zmijewska, R. Jope, 2007, Journal of cellular biochemistry.

Impaired Mitochondrial Dynamics and Nrf2 Signaling Contribute to Compromised Responses to Oxidative Stress in Striatal Cells Expressing Full-Length Mutant Huntingtin

G. Johnson, Soner Gundemir, Youngnam N. Jin, 2013, PloS one.

Role of the intracellular domains of LRP5 and LRP6 in activating the Wnt canonical pathway

G. Johnson, Kaihong Mi, 2005, Journal of cellular biochemistry.

Usp14 Deficiency Increases Tau Phosphorylation without Altering Tau Degradation or Causing Tau-Dependent Deficits

Jennifer A. Watson, L. Dobrunz, R. Schmidt, 2012, PloS one.

The Crosstalk Between Pathological Tau Phosphorylation and Mitochondrial Dysfunction as a Key to Understanding and Treating Alzheimer’s Disease

G. Johnson, K. Nehrke, Sanjib Guha, 2020, Molecular Neurobiology.

Alzheimer’s disease-relevant tau modifications selectively impact neurodegeneration and mitophagy in a novel C. elegans single-copy transgenic model

G. Johnson, K. Nehrke, Sarah Fischer, 2020, bioRxiv.

The interrelationship between selective tau phosphorylation and microtubule association

R. Jope, G. Johnson, J. A. Hartigan, 1998, Brain Research.

Halothane‐Induced Alterations of Glucose and Pyruvate Metabolism in Rat Cerebra Synaptosomes

G. Johnson, C. Hartzell, 1985, Journal of neurochemistry.

The p38 MAP kinase signaling pathway in Alzheimer’s disease

G. Johnson, C. Bailey, Gail V. W Johnson, 2003, Experimental Neurology.

Tissue transglutaminase contributes to disease progression in the R6/2 Huntington's disease mouse model via aggregate‐independent mechanisms

G. Johnson, C. Bailey, 2005, Journal of neurochemistry.

Validity of mouse models for the study of tissue transglutaminase in neurodegenerative diseases

R. Graham, G. Johnson, P. Davies, 2004, Molecular and Cellular Neuroscience.

Tissue Transglutaminase Is Increased in Huntington's Disease Brain

R. Ferrante, G. Johnson, W. Chun, 1999, Journal of neurochemistry.

Verification of somatic CAG repeat expansion by pre-PCR fractionation

P. Detloff, G. Johnson, J. Hunter, 2005, Journal of Neuroscience Methods.

Calpain‐mediated proteolysis of microtubule‐associated protein 2 (MAP‐2) is inhibited by phosphorylation by cAMP‐dependent protein kinase, but not by Ca2+/calmodulin‐dependent protein kinase II

G. Johnson, V. G. Foley, V. G. Foley, 1993, Journal of neuroscience research.

Phosphorylation, calpain proteolysis and tubulin binding of recombinant human tau isoforms

C. W. Scott, G. Johnson, J. Litersky, 1993, Brain Research.

Truncated tau and Aβ cooperatively impair mitochondria in primary neurons

P. Dolan, G. Johnson, R. Quintanilla, 2012, Neurobiology of Aging.

Split GFP complementation assay: a novel approach to quantitatively measure aggregation of tau in situ: effects of GSK3β activation and caspase 3 cleavage

G. Waldo, G. Johnson, W. Chun, 2007, Journal of neurochemistry.

The role of tau phosphorylation and cleavage in neuronal cell death.

G. Johnson, Gail V W Johnson, Wanjoo Chun, 2007, Frontiers in bioscience : a journal and virtual library.

Cdk5 phosphorylates p53 and regulates its activity

G. Johnson, Gail V W Johnson, Jianwen Zhang, 2002, Journal of neurochemistry.

Striatal cells from mutant huntingtin knock-in mice are selectively vulnerable to mitochondrial complex II inhibitor-induced cell death through a non-apoptotic pathway.

M. MacDonald, G. Johnson, M. Lesort, 2004, Human molecular genetics.

Tau Post-Translational Modifications: Potentiators of Selective Vulnerability in Sporadic Alzheimer’s Disease

G. Johnson, K. Nehrke, Sanjib Guha, 2021, Biology.

Effects of cyclin‐dependent kinase‐5 activity on apoptosis and tau phosphorylation in immortalized mouse brain cortical cells

G. Johnson, P. Krishnamurthy, S. B. Shelton, 2004, Journal of neuroscience research.

Tau Protein Is Hyperphosphorylated in a Site‐Specific Manner in Apoptotic Neuronal PC12 Cells

G. Johnson, J Zhang, G V Johnson, 2000, Journal of neurochemistry.

Transglutaminase 2 as a therapeutic target for neurological conditions

G. Johnson, J. Keillor, 2021, Expert opinion on therapeutic targets.

Transglutaminases and Neurological Diseases

G. Johnson, Julianne Feola, Laura Yunes-Medina, 2015 .

Ubiquitin‐proteasome system alterations in a striatal cell model of huntington's disease

G. Johnson, J. Hunter, M. Lesort, 2007, Journal of neuroscience research.

Mitochondrial permeability transition pore induces mitochondria injury in Huntington disease

G. Johnson, R. Quintanilla, Youngnam N. Jin, 2013, Molecular Neurodegeneration.

Type 2 transglutaminase differentially modulates striatal cell death in the presence of wild type or mutant huntingtin

G. Johnson, R. Quintanilla, Qingmin Ruan, 2007, Journal of neurochemistry.

Increased expression of Bim contributes to the potentiation of serum deprivation-induced apoptotic cell death in Huntington's disease knock-in striatal cell line

G. Johnson, Sung-soo Kim, W. Chun, 2009, Neurological research.

Autoregulatory control of E 2 F 1 expression in response to positive and negative regulators of cell cycle progression

Kiyoshi, David, G. Johnson, 2007 .

Tissue Transglutaminase Selectively Modifies Proteins Associated with Truncated Mutant Huntingtin in Intact Cells

M. MacDonald, C. Ross, G. Johnson, 2001, Neurobiology of Disease.

The role of tau kinases in Alzheimer's disease.

P. Dolan, G. Johnson, Philip J Dolan, 2010, Current opinion in drug discovery & development.

The last tangle of tau.

G. Johnson, H. Ding, 2008, Journal of Alzheimer's disease : JAD.

Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52

I. Rahman, G. Johnson, Soner Gundemir, 2014, Nature Communications.

Tau Clearance Mechanisms and Their Possible Role in the Pathogenesis of Alzheimer Disease

G. Johnson, Adrianne S. Chesser, Susanne Pritchard, 2013, Front. Neurol..

Select Alterations in Protein Kinases and Phosphatases During Apoptosis of Differentiated PC12 Cells

S. Dudek, G. Johnson, P. K. Davis, 1997, Journal of neurochemistry.

Modulation of the phosphorylation state of tau in situ: the roles of calcium and cyclic AMP.

G. Johnson, L. Fleming, 1995, The Biochemical journal.

It’s all about tau

G. Johnson, R. Quintanilla, C. Tapia-Rojas, 2019, Progress in Neurobiology.

Site-specific phosphorylation of tau impacts mitochondrial biology and response to stressors

G. Johnson, K. Nehrke, P. Girardi, 2023, bioRxiv.

Tau, where are we now?

G. Johnson, C. Bailey, 2002, Journal of Alzheimer's disease : JAD.

Cystamine Inhibits Caspase Activity

G. Johnson, J. Tucholski, Matthew Lee, 2003, The Journal of Biological Chemistry.

Fisetin stimulates autophagic degradation of phosphorylated tau via the activation of TFEB and Nrf2 transcription factors

G. Johnson, Y. Koh, J. Jeon, 2016, Scientific Reports.

Tau facilitates Aβ-induced loss of mitochondrial membrane potential independent of cytosolic calcium fluxes in mouse cortical neurons

G. Johnson, S. Pallo, 2015, Neuroscience Letters.

Glycogen synthase kinase 3beta phosphorylates tau at both primed and unprimed sites. Differential impact on microtubule binding.

J. Cho, G. Johnson, 2003, The Journal of biological chemistry.

Epigallocatechin-3-gallate enhances clearance of phosphorylated tau in primary neurons

G. Johnson, Adrianne S. Chesser, Veena R. Ganeshan, 2016, Nutritional neuroscience.

The protective effects of cystamine in the R6/2 Huntington's disease mouse involve mechanisms other than the inhibition of tissue transglutaminase

G. Johnson, C. Bailey, 2006, Neurobiology of Aging.

Cystamine treatment is neuroprotective in the YAC128 mouse model of Huntington disease

M. Hayden, B. Leavitt, G. Johnson, 2005, Journal of neurochemistry.

Metal-catalyzed oxidation of bovine neurofilaments in vitro.

J. Troncoso, G. Johnson, J. Kim, 1995, Free radical biology & medicine.

Quinacrine and 2-(4-phenylpiperidino)cyclohexanol (AH5183) inhibit acetylcholine release and synthesis in rat brain slices.

R. Jope, G. Johnson, 1986, Molecular pharmacology.

Dose- and time-dependent hippocampal cholinergic lesions induced by ethylcholine mustard aziridinium ion: Effects of nerve growth factor, GM1 ganglioside, and vitamin E

R. Jope, G. Johnson, M. Simonato, 1988, Neurochemical Research.

Mutant huntingtin aggregates do not sensitize cells to apoptotic stressors

Matthew Lee, G. Johnson, Gail V W Johnson, 2002, FEBS letters.

Does tissue transglutaminase play a role in Huntington's disease?

G. Johnson, J. Tucholski, W. Chun, 2002, Neurochemistry International.

Tau Clearance Mechanisms.

G. Johnson, Maoping Tang, Carol A. Deaton, 2019, Advances in experimental medicine and biology.

Direct, activating interaction between glycogen synthase kinase-3β and p53 after DNA damage

Ling Song, Richard S. Jope, Xinbin Chen, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of transglutaminase 2, a novel target for pulmonary fibrosis, by two small electrophilic molecules.

Thomas H Thatcher, Richard P Phipps, G. Johnson, 2014, American journal of respiratory cell and molecular biology.

Differential Binding of Apolipoprotein E Isoforms to Tau and Other Cytoskeletal Proteins

J. Troncoso, W. Strittmatter, K. Weisgraber, 1996, Experimental Neurology.

Phosphorylation of microtubule-associated protein tau on Ser 262 by an embryonic 100 kDa protein kinase

G. Johnson, S. Jenkins, 1997, Brain Research.

Phosphorylation of τ In Situ: Inhibition of Calcium‐Dependent Proteolysis

G. Johnson, J. Litersky, 1995, Journal of neurochemistry.

Insulin-like growth factor-1 and insulin mediate transient site-selective increases in tau phosphorylation in primary cortical neurons

G. Johnson, M. Lesort, 2000, Neuroscience.

Tissue Transglutaminase Directly Regulates Adenylyl Cyclase Resulting in Enhanced cAMP-response Element-binding Protein (CREB) Activation*

G. Johnson, J. Tucholski, 2003, Journal of Biological Chemistry.

Impaired Mitochondrial Function Results in Increased Tissue Transglutaminase Activity In Situ

G. Johnson, J. Tucholski, M. Lesort, 2000, Journal of neurochemistry.

The Low Density Lipoprotein Receptor-related Protein 6 Interacts with Glycogen Synthase Kinase 3 and Attenuates Activity*

P. Dolan, G. Johnson, Kaihong Mi, 2006, Journal of Biological Chemistry.

Rosiglitazone Treatment Prevents Mitochondrial Dysfunction in Mutant Huntingtin-expressing Cells

G. Johnson, R. Quintanilla, Youngnam N. Jin, 2008, Journal of Biological Chemistry.

BAG3 regulates the specificity of the recognition of specific MAPT species by NBR1 and SQSTM1

G. Johnson, Heng Lin, Sarah Sandkuhler, 2023, bioRxiv.

Site-specific Phosphorylation and Caspase Cleavage Differentially Impact Tau-Microtubule Interactions and Tau Aggregation*

T. Matthews, G. Johnson, H. Ding, 2006, Journal of Biological Chemistry.

Identification of the N‐terminal functional domains of Cdk5 by molecular truncation and computer modeling

Kuo-Chen Chou, Chi-Hao Luan, K. Chou, 2002, Proteins.

Deletion of Transglutaminase 2 from Mouse Astrocytes Significantly Improves Their Ability to Promote Neurite Outgrowth on an Inhibitory Matrix

G. Johnson, P. Girardi, Thomas Delgado, 2023, International journal of molecular sciences.

Deletion of transglutaminase 2 from astrocytes significantly improves their ability to promote neurite outgrowth on an inhibitory matrix

G. Johnson, P. Girardi, Thomas Delgado, 2023, bioRxiv.

Deletion or Inhibition of Astrocytic Transglutaminase 2 Promotes Functional Recovery after Spinal Cord Injury

G. Johnson, A. Elahi, Garrick Salois, 2021, bioRxiv.

Nuclear transglutaminase 2 directly regulates expression of cathepsin S in rat cortical neurons

G. Johnson, Maoping Tang, Changyi Ji, 2018, The European journal of neuroscience.

Differential Phosphorylation of τ by Cyclic AMP‐Dependent Protein Kinase and Ca2+/Calmodulin‐Dependent Protein Kinase II: Metabolic and Functional Consequences

G. Johnson, 1992 .

The role of tau phosphorylation in the pathogenesis of Alzheimer's disease.

G. Johnson, Kaihong Mi, 2006, Current Alzheimer research.

Differential Modulation of TCF/LEF-1 Activity by the Soluble LRP6-ICD

G. Johnson, Brandon R. Beagle, 2010, PloS one.

Increased glutathione levels in cortical and striatal mitochondria of the R6/2 Huntington's disease mouse model

G. Johnson, Yeun Su Choo, M. Lesort, 2005, Neuroscience Letters.

The application of permanent middle cerebral artery ligation in the mouse.

G. Johnson, A. Filiano, G. Colak, 2011, Journal of visualized experiments : JoVE.

Complement activation by neurofibrillary tangles in Alzheimer's disease

Virginia M. Y. Lee, L. Lue, B. Bradt, 2001, Neuroscience Letters.

Tissue Transglutaminase Does Not Contribute to the Formation of Mutant Huntingtin Aggregates

C. Ross, G. Johnson, J. Tucholski, 2001, The Journal of cell biology.

Transglutaminase Cross‐Linking of the τ Protein

G. Johnson, Michael L. Miller, M. L. Miller, 1995 .

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Transglutaminase cross-linking of the tau protein.

G. Johnson, M. Miller, 1995, Journal of neurochemistry.

SULFORAPHANE PROMOTES THE DEGRADATION OF PHOSPHORYLATED TAU VIA THE INDUCTION OF AUTOPHAGY

S. I. Park, G. Johnson, Y. Koh, 2014, Alzheimer's & Dementia.

Immunoblot analysis reveals that isopeptide antibodies do not specifically recognize the epsilon-(gamma-glutamyl)lysine bonds formed by transglutaminase activity.

G. Johnson, Reginald LeShoure, 2004, Journal of neuroscience methods.

Tissue Transglutaminase-Mediated AT1 Receptor Sensitization Underlies Pro-inflammatory Cytokine LIGHT-Induced Hypertension

G. Johnson, Yang Xia, R. Kellems, 2019, American journal of hypertension.

Modulation of tau phosphorylation and intracellular localization by cellular stress.

G. Johnson, C. Garner, M. Zinnerman, 2000, The Biochemical journal.

Energy metabolism and protein phosphorylation during apoptosis: a phosphorylation study of tau and high-molecular-weight tau in differentiated PC12 cells.

G. Johnson, P. K. Davis, Gail V. W. Johnson, 1999, The Biochemical journal.

Tau complexes with phospholipase C-gamma in situ.

G. Johnson, S. Jenkins, 1998, Neuroreport.

In vitro polymerization of oxidized tau into filaments

A. L. Watson, J. Troncoso, G. Johnson, 1993, Brain Research.

Dietary aluminum selectively decreases MAP-2 in brains of developing and adult rats.

A. L. Watson, R. Jope, G. Johnson, 1992, Neurotoxicology.

Postnatal changes in serine/threonine protein phosphatases and their association with the microtubules.

S. Dudek, G. Johnson, 1995, Brain research. Developmental brain research.

In vitro measurements of cholinergic activity in brain regions of hibernating ground squirrels

G. Johnson, T. L. Stanton, 1987, Brain Research Bulletin.

Energy metabolism and protein phosphorylation during apoptosis : a phosphorylation study of tau and high-molecular-weight tau in differentiated PC 12 cells *

G. Johnson, P. K. Davis, 1999 .

NDP52 associates with phosphorylated tau in brains of an Alzheimer disease mouse model.

G. Johnson, Y. Koh, Sunhyo Kim, 2014, Biochemical and biophysical research communications.

Glycogen synthase kinase 3 beta induces caspase-cleaved tau aggregation in situ.

J. Cho, G. Johnson, 2004, The Journal of biological chemistry.

Selective Disruption of Drp1-Independent Mitophagy and Mitolysosome Tra cking by an Alzheimer’s Disease Relevant Tau Modi cation in a Novel C. elegans Model

G. Johnson, K. Nehrke, D. King, 2021 .

Endostatin and transglutaminase 2 are involved in fibrosis of the aging kidney.

M. Goligorsky, T. Pihlajaniemi, G. Johnson, 2016, Kidney international.

Tissue transglutaminase is not involved in the aggregate formation of stably expressed α-synuclein in sh-sy5y human neuroblastoma cells

G. Johnson, Sung-soo Kim, W. Chun, 2004, Archives of pharmacal research.