D. Berwick

发表

PI3K, PTEN and Akt

T. Franke, D. Berwick, 2005 .

LRRK 2 functions as a Wnt signaling scaffold , bridging cytosolic proteins and membrane-localized LRP 6

D. Berwick, K. Harvey, 2012 .

Protein kinase B phosphorylation of PIKfyve regulates the trafficking of GLUT4 vesicles

J. Tavaré, I. Hers, L. Fletcher, 2004, Journal of Cell Science.

Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling

A. Pitsillides, D. Berwick, K. Harvey, 2017, Molecular Neurodegeneration.

L'RRK de Triomphe: a solution for LRRK2 GTPase activity?

D. Berwick, K. Harvey, Jonathon Nixon-Abell, 2016, Biochemical Society transactions.

The development of inhibitors of LRRK2 as a therapeutic strategy for Parkinson’s disease: the current state of play

D. Berwick, Sonia Azeggagh, 2021 .

Regulation Of Brn-3a N-terminal transcriptional activity by MEK1/2-ERK1/2 signalling in neural differentiation

S. Cook, D. Latchman, D. Berwick, 2009, Brain Research.

Open Research Online The development of inhibitors of leucinerich repeat kinase 2 (LRRK2) as a therapeutic strategy for Parkinson’s disease: the current state of play

D. Berwick, Sonia Azeggagh, 2022 .

The Identification of ATP-citrate Lyase as a Protein Kinase B (Akt) Substrate in Primary Adipocytes*

J. Tavaré, I. Hers, D. Berwick, 2002, The Journal of Biological Chemistry.

The regulation and deregulation of Wnt signaling by PARK genes in health and disease

D. Berwick, K. Harvey, 2013, Journal of molecular cell biology.

The importance of Wnt signalling for neurodegeneration in Parkinson's disease.

Kirsten Harvey, D. Berwick, K. Harvey, 2012, Biochemical Society transactions.

LRRK2 Biology from structure to dysfunction: research

D. Berwick, K. Harvey, George R. Heaton, 2020 .

LRRK2 Biology from structure to dysfunction: research progresses, but the themes remain the same

D. Berwick, K. Harvey, George R. Heaton, 2019, Molecular Neurodegeneration.

A Direct Interaction between Leucine-rich Repeat Kinase 2 and Specific β-Tubulin Isoforms Regulates Tubulin Acetylation*

H. Cai, M. Cookson, V. Baekelandt, 2013, The Journal of Biological Chemistry.

Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus

J. Rain, V. Plagnol, D. Berwick, 2019, Scientific Reports.

Identifying protein kinase substrates: hunting for the organ-grinder's monkeys.

J. Tavaré, D. Berwick, 2004, Trends in biochemical sciences.

The development of inhibitors of leucine‐rich repeat kinase 2 (LRRK2) as a therapeutic strategy for Parkinson's disease: the current state of play

D. Berwick, Sonia Azeggagh, 2021, British journal of pharmacology.

The development of inhibitors of leucinerich repeat kinase 2 (LRRK2) as a therapeutic strategy for Parkinson’s disease: the current state of play

D. Berwick, Sonia Azeggagh, 2021 .

Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling

A. Pitsillides, D. Berwick, K. Harvey, 2017, Molecular Neurodegeneration.

A Simple Technique for the Prediction of Interacting Proteins Reveals a Direct Brn-3a-Androgen Receptor Interaction*

D. Latchman, V. Budhram-Mahadeo, D. Berwick, 2010, The Journal of Biological Chemistry.

Role of protein kinase B in insulin-regulated glucose uptake.

J. Tavaré, I. Hers, D. Berwick, 2005, Biochemical Society transactions.

The relevance of α-KLOTHO to the central nervous system: Some key questions

C. Scavone, D. Berwick, C. Mazucanti, 2017, Ageing Research Reviews.

LRRK2: an éminence grise of Wnt-mediated neurogenesis?

D. Berwick, K. Harvey, 2013, Front. Cell. Neurosci..

LRRK2 signaling pathways: the key to unlocking neurodegeneration?

D. Berwick, K. Harvey, 2011, Trends in cell biology.

RegulationOfBrn-3aN-terminaltranscriptionalactivityby MEK1/2-ERK1/2signallinginneuraldifferentiation

S. Cook, D. Berwick, 2008 .

LRRK 2 : an nence grise of Wnt-mediated neurogenesis ?

D. Berwick, K. Harvey, 2016 .

LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6

D. Berwick, K. Harvey, 2012, Human molecular genetics.

Protective LRRK2 R1398H Variant Enhances GTPase and Wnt Signaling Activity

C. Blackstone, D. Berwick, K. Harvey, 2016, Front. Mol. Neurosci..