P. Innocenti

发表

Inhibition of the phosphatidylinositol 3-kinase/Akt pathway by inositol pentakisphosphate results in antiangiogenic and antitumor effects.

Adolfo Saiardi, Stefano Iacobelli, A. M. Riley, 2005, Cancer research.

Benzimidazole inhibitors induce a DFG-out conformation of never in mitosis gene A-related kinase 2 (Nek2) without binding to the back pocket and reveal a nonlinear structure-activity relationship.

R. V. van Montfort, K. Boxall, G. Aherne, 2011, Journal of medicinal chemistry.

Characterisation of CCT271850, a selective, oral and potent MPS1 inhibitor, used to directly measure in vivo MPS1 inhibition vs therapeutic efficacy

A. Faisal, M. Valenti, A. K. de Haven Brandon, 2017, British Journal of Cancer.

Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization Approach.

R. V. van Montfort, A. Faisal, N. Cronin, 2016, Journal of medicinal chemistry.

Recent Advances in the Development of Semisynthetic Glycopeptide Antibiotics: 2014–2022

P. Innocenti, N. Martin, Emma van Groesen, 2022, ACS infectious diseases.

Thermal elimination of diethyldithiocarbamates and application in the synthesis of (+/-)-ferrugine.

P. Innocenti, C. Quevedo, Shamim Ahmed, 2008, The Journal of organic chemistry.

Dithiocarbamate group transfer cyclization reactions of carbamoyl radicals under "tin-free" conditions.

P. Innocenti, R. Grainger, 2004, Angewandte Chemie.

Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays

O. Rossanese, Benjamin R Bellenie, R. V. van Montfort, 2022, Scientific Reports.

Phosphato complexes of beryllium(II): a 31P and 9Be nuclear magnetic resonance study

P. Innocenti, M. Iuliano, A. Vacca, 2000 .

Breast development in adolescent girls

P. Innocenti, V. Bruni, M. Dei, 1990 .

Synthesis and Structure–Activity Studies of β-Barrel Assembly Machine Complex Inhibitor MRL-494

P. Innocenti, G. Koningstein, J. Luirink, 2022, ACS infectious diseases.

Surface plasmon resonance imaging of glycoarrays identifies novel and unnatural carbohydrate-based ligands for potential ricin sensor development

David A. Russell, D. A. Russell, Timothy J. Donohoe, 2011 .

Influence of the Catalytic System on the Methanolysis of Polyethylene Terephthalate at Mild Conditions: A Systematic Investigation

P. Innocenti, D. Moscatelli, M. Sponchioni, 2022, Chemical Engineering Science.

New Applications of Dithiocarbamates in Organic Synthesis

P. Innocenti, R. Grainger, 2007 .

Inositol pentakisphosphate promotes apoptosis through the PI 3-K/Akt pathway

A. M. Riley, P. Pandolfi, S. Iacobelli, 2004, Oncogene.

Expanding the scope of fused pyrimidines as kinase inhibitor scaffolds: synthesis and modification of pyrido[3,4-d]pyrimidines.

P. Innocenti, S. Hoelder, H. Woodward, 2015, Organic & biomolecular chemistry.

Synthesis and dynamic stereochemistry of the complexes [Pt{CH3C(CH2PPh2)3}(SR)(H)](R = H or Ph)

P. Innocenti, A. Vacca, J. Ramírez, 1991 .

Synthesis and characterisation of the five diastereoisomers of 4,7,13,16-tetraphenyl-1,10-dithia-4,7,13,16-tetraphosphacyclo-octadecane: crystal structure of the nickel bromide complex of the β-isomer

P. Innocenti, M. Ciampolini, N. Nardi, 1984 .

Hydrogen‐Bonding‐Mediated Directed Osmium Dihydroxylation

P. Innocenti, C. Bataille, T. Donohoe, 2012 .

Reactivity of the triethylphosphinecarbon disulfide adduct Et3PCS2 toward iron(II) cations in the presence of the bis(tertiary phosphines), depe, and diphos, x-ray crystal structures of the complexes [(depe)2Fe(S2CPEt3)](BPh4)2 and [(depe)2Fe(S2CH)](BPh4)

P. Innocenti, A. Orlandini, C. Bianchini, 1982 .

Reactions of the trigonal-bipyramidal cobalt(I) hydride [{P(CH2CH2PPH2)3}CoH] with 1-alkynes. Synthesis and reactivity of acethylide, alkenyl, and vinylidene complexes

M. Peruzzini, P. Innocenti, C. Bianchini, 1990 .

Dynamic nuclear magnetic resonance studies of the η3-triphenylcyclopropenyl complexes [M(η3-C3Ph3)L]PF6[M = Ni, Pd or Pt; L = MeC(CH2PPh2)3]. Crystal structure of the platinum derivative

P. Innocenti, A. Orlandini, A. Vacca, 1995 .

Reactivity of diphosphines towards methyl- and phenyl-mercury(II) ions. Crystal structure of [Hg(Ph2PCH2CH2PPh2)2][O3SCF3]2

P. Innocenti, A. Ienco, A. Orlandini, 1996 .

Synthesis, properties, and x-ray structural characterization of cationic five-coordinate .sigma.-alkylnickel(II) compounds with poly(tertiary phosphines and arsines)

P. Innocenti, P. Stoppioni, C. Benelli, 1977 .

Synthesis and structural study of a cobalt complex with the diarsenic-sulfur cyclic unit as a trihapto ligand

M. Peruzzini, P. Innocenti, P. Stoppioni, 1984 .

REDUCTIVE INTRAMOLECULAR HYDROGEN TRANSFER IN A D8 METAL HYDRIDE PROMOTED BY CARBON MONOXIDE ADDITION. AN EXPERIMENTAL STUDY AND ITS THEORETICAL IMPLICATIONS

P. Innocenti, C. Mealli, A. Orlandini, 1984 .

C−C Bond Formation between Vinylidene and Alkynyl Ligands at Ruthenium(II) Leading to either Enynyl or Dienynyl Complexes†

M. Peruzzini, P. Innocenti, C. Bianchini, 1996 .

Reactions of HC.tplbond.CCO2Et with (np3)CoH and (np3)Ni [np3 = N(CH2CH2PPh2)3]. Crystal structures of the alkenyl complexes [(np3)CoC(CO2Et):CH2]BPh4.cntdot.0.5THF and [(np3)NiCH:CHC(O)OEt]BPh4

P. Innocenti, C. Bianchini, A. Meli, 1986 .

Vancomyxins: Vancomycin-Polymyxin Nonapeptide Conjugates That Retain Anti-Gram-Positive Activity with Enhanced Potency against Gram-Negative Strains

P. Innocenti, R. Masereeuw, M. Mihajlovic, 2021, ACS infectious diseases.

Immunogenic males: a genome‐wide analysis of reproduction and the cost of mating in Drosophila melanogaster females

P. Innocenti, E. H. Morrow, 2009, Journal of evolutionary biology.

Interspecific divergence of transcription networks along lines of genetic variance in Drosophila: dimensionality, evolvability, and constraint.

P. Innocenti, S. Chenoweth, 2013, Molecular biology and evolution.

Sexual Conflict and Gene Expression in Drosophila melanogaster

P. Innocenti, 2011 .

Experimental Evidence Supports a Sex-Specific Selective Sieve in Mitochondrial Genome Evolution

P. Innocenti, D. K. Dowling, E. H. Morrow, 2011, Science.

Tackling Crizotinib Resistance: The Pathway from Drug Discovery to the Pediatric Clinic.

P. Innocenti, L. Chesler, L. Danielson, 2015, Cancer research.

Female Drosophila melanogaster Gene Expression and Mate Choice: The X Chromosome Harbours Candidate Genes Underlying Sexual Isolation

P. Innocenti, A. Qvarnström, E. H. Morrow, 2011, PloS one.

The Sexually Antagonistic Genes of Drosophila melanogaster

P. Innocenti, E. H. Morrow, Paolo Innocenti, 2010, PLoS biology.

Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders

O. Rossanese, Benjamin R Bellenie, R. V. van Montfort, 2020, Journal of medicinal chemistry.

Female postmating immune responses, immune system evolution and immunogenic males

P. Innocenti, E. H. Morrow, Edward H. Morrow, 2012, Biological reviews of the Cambridge Philosophical Society.

Female responses to experimental removal of sexual selection components in Drosophila melanogaster

P. Innocenti, E. H. Morrow, I. Flis, 2014, BMC Evolutionary Biology.

Rapid evolution of the intersexual genetic correlation for fitness in Drosophila melanogaster

J. Hesketh, Kevin Fowler, M. Reuter, 2016, Evolution; international journal of organic evolution.

Rapid evolution of the inter-sexual genetic correlation for fitness in Drosophila melanogaster

J. Hesketh, Kevin Fowler, M. Reuter, 2015, bioRxiv.

Sexual conflict and gene expression: Exploring sex-specific associations between fitness and transcriptional variation.

P. Innocenti, 2011, Fly.

A JOINT INDEX FOR THE INTENSITY OF SEX‐SPECIFIC SELECTION

P. Innocenti, E. H. Morrow, Edward H. Morrow, 2010, Evolution; international journal of organic evolution.

Epigenetics and Sex-Specific Fitness: An Experimental Test Using Male-Limited Evolution in Drosophila melanogaster

P. Innocenti, A. Chippindale, J. Abbott, 2013, PloS one.

Between‐sex genetic covariance constrains the evolution of sexual dimorphism in Drosophila melanogaster

H. Rundle, P. Innocenti, E. H. Morrow, 2014, Journal of evolutionary biology.

Synthesis of amino-substituted indoles using the Bartoli reaction.

P. Innocenti, S. Hoelder, D. Whelligan, 2012, Organic & biomolecular chemistry.

Potent Inhibition of Nicotinamide N-Methyltransferase by Alkene-Linked Bisubstrate Mimics Bearing Electron Deficient Aromatics

Gerard J. P. van Westen, H. Gutiérrez‐de‐Terán, P. Innocenti, 2021, Journal of medicinal chemistry.

High Proliferation Rate and a Compromised Spindle Assembly Checkpoint Confers Sensitivity to the MPS1 Inhibitor BOS172722 in Triple-Negative Breast Cancers

R. V. van Montfort, A. Faisal, F. Raynaud, 2019, Molecular Cancer Therapeutics.

Design of potent and selective hybrid inhibitors of the mitotic kinase Nek2: structure-activity relationship, structural biology, and cellular activity.

K. Boxall, G. Aherne, R. Bayliss, 2012, Journal of medicinal chemistry.

Design of potent and selective hybrid inhibitors of the mitotic kinase Nek2: SAR, structural biology and cellular activity

Swen, K. Boxall, G. Aherne, 2012 .

Introduction of a Methyl Group Curbs Metabolism of Pyrido[3,4-d]pyrimidine Monopolar Spindle 1 (MPS1) Inhibitors and Enables the Discovery of the Phase 1 Clinical Candidate N2-(2-Ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine (BOS172722)

R. V. van Montfort, A. Faisal, N. Cronin, 2018, Journal of medicinal chemistry.

THE B‐MATRIX HARBORS SIGNIFICANT AND SEX‐SPECIFIC CONSTRAINTS ON THE EVOLUTION OF MULTICHARACTER SEXUAL DIMORPHISM

P. Innocenti, S. Chenoweth, T. Gosden, 2012, Evolution; international journal of organic evolution.

Synthesis and Evaluation of Polymyxins Bearing Reductively Labile Disulfide-Linked Lipids

P. Innocenti, K. Westphal, R. Masereeuw, 2022, Journal of medicinal chemistry.

Characterisation of CCT271850, a selective, oral and potent MPS1 inhibitor, used to directly measure in vivo MPS1 inhibition vs therapeutic efficacy

A. Faisal, M. Valenti, A. K. de Haven Brandon, 2017, British Journal of Cancer.

Length of index and ring fingers differentially influence sexual attractiveness of men’s and women’s hands

P. Innocenti, N. Saino, M. Romano, 2006, Behavioral Ecology and Sociobiology.

Determination of Ligand-Binding Affinity (Kd) Using Transverse Relaxation Rate (R2) in the Ligand-Observed 1H NMR Experiment and Applications to Fragment-Based Drug Discovery.

Benjamin R Bellenie, R. V. van Montfort, A. Mirza, 2023, Journal of medicinal chemistry.

Genome-wide targets of selection: female response to experimental removal of sexual selection in Drosophila melanogaster

P. Innocenti, E. H. Morrow, I. Flis, 2013, bioRxiv.

THE B-MATRIX HARBORS SIGNIFICANT AND SEX-SPECIFIC CONSTRAINTS ON THE EVOLUTION OF MULTICHARACTER SEXUAL DIMORPHISM: MULTIVARIATE GENETIC CONSTRAINTS ON SEXUAL DIMORPHISM

P. Innocenti, S. Chenoweth, T. Gosden, 2012 .

Synthesis, characterization, and structure of the complex [FeH(H2BH2){CH3C(CH2PPh2)3}]

P. Innocenti, A. Orlandini, C. A. Ghilardi, 1985 .