B. Baumann

发表

NF-κB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression

Andreas Sommer, H. Pehamberger, H. Beug, 2004 .

RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP‐J

J. Wiedenmann, F. Oswald, G. Nienhaus, 2011, The EMBO journal.

Synergistic activity of sorafenib and sulforaphane abolishes pancreatic cancer stem cell characteristics.

M. Büchler, I. Herr, M. Zöller, 2010, Cancer research.

Sustained JNK Activation in Response to Tumor Necrosis Factor Is Mediated by Caspases in a Cell Type-specific Manner*

N. Müller, R. Marienfeld, H. Wajant, 2007, Journal of Biological Chemistry.

H. Augustin, A. Aguzzi, M. Heikenwalder, 2019, Cancer cell.

Rocaglamide Derivatives Are Potent Inhibitors of NF-κB Activation in T-cells*

I. Herr, H. Wajant, T. Wirth, 2002, The Journal of Biological Chemistry.

Activity of a novel bcl-2/bcl-xL-bispecific antisense oligonucleotide against tumors of diverse histologic origins.

R. Stahel, J. Hall, B. Baumann, 2001, Journal of the National Cancer Institute.

Deficiency of innate and acquired immunity caused by an IKBKB mutation.

U. Pannicke, K. Schwarz, S. Ehl, 2013, The New England journal of medicine.

IKK mediates ischemia-induced neuronal death

M. T. Hasan, H. Bujard, M. Köhrmann, 2005, Nature Medicine.

Bim and Noxa Are Candidates to Mediate the Deleterious Effect of the NF-κB Subunit RelA in Cerebral Ischemia

D. Inta, P. Spano, R. Schmid, 2006, The Journal of Neuroscience.

Characterization of sonic hedgehog as a novel NF‐κB target gene that promotes NF‐κB‐mediated apoptosis resistance and tumor growth in vivo

B. Baumann, K. Debatin, H. Kasperczyk, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Requirement of NEMO/IKKγ for effective expansion of KRAS-induced precancerous lesions in the pancreas

T. Wirth, B. Baumann, H. Salem, 2013, Oncogene.

Lack of correlation between NF-kappaB activation and induction of programmed cell death in PC12 pheochromocytoma cells treated with 6-hydroxydopamine or the cannabinoid receptor 1-agonist CP55,940.

T. Wirth, B. Baumann, G. Thiel, 2002, Biochemical pharmacology.

The Mutant Plasmacytoma Cell Line S107 Allows the Identification of Distinct Pathways Leading to NF-κB Activation*

Y. Bergman, B. Kistler, T. Wirth, 1998, The Journal of Biological Chemistry.

RelB is a Key Player for Both κB-Depenclent Transcription and Demethylation in B Cells

Y. Bergman, B. Kistler, T. Wirth, 1997 .

Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo.

T. Wirth, B. Baumann, C. Weber, 2007, The Journal of clinical investigation.

NF-κB induces PGE2-synthesizing enzymes in neurons

M. Schwaninger, B. Baumann, W. Barakat, 2009, Naunyn-Schmiedeberg's Archives of Pharmacology.

Nuclear Factor κB Activation Impairs Ependymal Ciliogenesis and Links Neuroinflammation to Hydrocephalus Formation

P. Walther, T. Wirth, B. Baumann, 2012, The Journal of Neuroscience.

Signal Transduction Inhibition of NFk B Signaling Ablates the Invasive Phenotype of Glioblastoma

N. Carragher, C. Wirtz, B. Baumann, 2013 .

The IKK2/NF- (cid:1) B pathway suppresses MYC-induced lymphomagenesis

T. Wirth, Dragan Marinkovic, B. Baumann, 2009 .

GSE17129: The IKK2/NF-kB-pathway suppresses MYC-induced lymphomagenesis

T. Wirth, B. Baumann, Kay Klapproth, 2009 .

Caspase-mediated Cleavage Converts the Tumor Necrosis Factor (TNF) Receptor-associated Factor (TRAF)-1 from a Selective Modulator of TNF Receptor Signaling to a General Inhibitor of NF-κB Activation*

P. Scheurich, H. Wajant, T. Wirth, 2003, Journal of Biological Chemistry.

Rocaglamide derivatives are potent inhibitors of NF-kappa B activation in T-cells.

I. Herr, H. Wajant, T. Wirth, 2002, The Journal of biological chemistry.

Sustained, neuron-specific IKK/NF-κB activation generates a selective neuroinflammatory response promoting local neurodegeneration with aging

T. Wirth, B. Baumann, A. Maqbool, 2013, Molecular Neurodegeneration.

Neuronal redox imbalance results in altered energy homeostasis and early postnatal lethality

T. Wirth, B. Baumann, D. Thal, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Inhibition of Nuclear Factor κB Activation Attenuates Apoptosis Resistance in Lymphoid Cells

I. Herr, I. Jeremias, T. Wirth, 1998 .

Anti-Inflammatory Therapy in Type 1 Diabetes

B. Boehm, B. Baumann, H. Salem, 2012, Current Diabetes Reports.

Differential Regulation of NF-κB-Mediated Proviral and Antiviral Host Gene Expression by Primate Lentiviral Nef and Vpu Proteins

C. Van Lint, F. Kirchhoff, B. Hahn, 2015, Cell reports.

Human RIPK1 deficiency causes combined immunodeficiency and inflammatory bowel diseases

U. Pannicke, K. Schwarz, C. Klein, 2018, Proceedings of the National Academy of Sciences.

A paired comparison between glioblastoma “stem cells” and differentiated cells

B. Baumann, K. Debatin, M. Halatsch, 2016, International journal of cancer.

Blocking distinct interactions between Glioblastoma cells and their tissue microenvironment: A novel multi-targeted therapeutic approach

N. Carragher, K. Föhr, P. Fischer-Posovszky, 2018, Scientific Reports.

NF-kappaB transcription factors: critical regulators of hematopoiesis and neuronal survival.

T. Wirth, B. Baumann, A. Denk, 2000, Cytokine & growth factor reviews.

Hepatic activation of IKK/NFκB signaling induces liver fibrosis via macrophage‐mediated chronic inflammation

T. Luedde, S. Kochanek, T. Wirth, 2012, Hepatology.

Proteasome Inhibition Results in TRAIL Sensitization of Primary Keratinocytes by Removing the Resistance-Mediating Block of Effector Caspase Maturation

E. Bröcker, M. Neumann, M. Goebeler, 2003, Molecular and Cellular Biology.

The PMN-MDSC – A key player in glucocorticoid resistance following combined physical and psychosocial trauma

H. Gündel, T. Wirth, M. Huber-Lang, 2022, Brain, Behavior, and Immunity.

NF-k B is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression

H. Pehamberger, H. Beug, T. Wirth, 2018 .

Critical Role of RelB Serine 368 for Dimerization and p100 Stabilization*

Harald J. Maier, R. Marienfeld, T. Wirth, 2003, Journal of Biological Chemistry.

A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy.

D. Fabbro, R. Stahel, B. Baumann, 2000, Cancer research.

NF-κB: Critical Regulator of Inflammation and the Immune Response

A. Lasar, R. Marienfeld, T. Wirth, 2004 .

Raf induces NF-kappaB by membrane shuttle kinase MEKK1, a signaling pathway critical for transformation.

T. Wirth, J. Troppmair, U. Rapp, 2000, Proceedings of the National Academy of Sciences of the United States of America.

NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression.

H. Pehamberger, H. Beug, T. Wirth, 2004, The Journal of clinical investigation.

Activation of the IκB kinase complex is sufficient for neuronal differentiation of PC12 cells

T. Wirth, N. Azoitei, B. Baumann, 2005, Journal of neurochemistry.

NF‐κB activation in astrocytes drives a stage‐specific beneficial neuroimmunological response in ALS

T. Boeckers, C. Rapôso, A. Ludolph, 2018, The EMBO journal.

Cellular immune reaction in the pancreas is induced by constitutively active IκB kinase-2

T. Wirth, B. Baumann, C. Weber, 2006, Gut.

A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency

U. Pannicke, K. Schwarz, J. Casanova, 2023, Science Immunology.

IKK2/NF-κB signaling protects neurons after traumatic brain injury

V. Rasche, T. Wirth, M. Huber-Lang, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegeneration

V. Rasche, P. Walther, T. Wirth, 2017, Molecular Neurodegeneration.

STAT6 mediates the effect of ethanol on neuroinflammatory response in TBI

T. Boeckers, A. Ludolph, T. Wirth, 2019, Brain, Behavior, and Immunity.

Identification of a novel pro-apopotic function of NF-κB in the DNA damage response

L. Wiesmüller, S. Fulda, B. Baumann, 2009, Journal of cellular and molecular medicine.

IKK2/NF-κB Activation in Astrocytes Reduces amyloid β Deposition: A Process Associated with Specific Microglia Polarization

F. Oswald, T. Wirth, B. Baumann, 2021, Cells.

The IKK2/NF-{kappa}B pathway suppresses MYC-induced lymphomagenesis.

T. Wirth, Dragan Marinkovic, B. Baumann, 2009, Blood.

Neuronal cell death induced by antidepressants: lack of correlation with Egr-1, NF-kappa B and extracellular signal-regulated protein kinase activation.

T. Wirth, B. Baumann, G. Thiel, 2002, Biochemical pharmacology.

Role of caspases in CD95L- and TRAIL-induced non-apoptotic signalling in pancreatic tumour cells.

H. Wajant, H. Kalthoff, B. Baumann, 2007, Cellular signalling.

Inhibition of NF-κB Signaling Ablates the Invasive Phenotype of Glioblastoma

N. Carragher, C. Wirtz, B. Baumann, 2013, Molecular Cancer Research.

The dynactin p150 subunit: cell biology studies of sequence changes found in ALS/MND and Parkinsonian Syndromes

P. Wong, T. Boeckers, A. Ludolph, 2013, Journal of Neural Transmission.

Multiplexed chemogenetics in astrocytes and motoneurons restore blood–spinal cord barrier in ALS

T. Boeckers, A. Ludolph, T. Wirth, 2020, Life Science Alliance.

NF-κB regulates DNA double-strand break repair in conjunction with BRCA1–CtIP complexes

L. Wiesmüller, S. Fulda, B. Baumann, 2011, Nucleic acids research.

IκB Kinase/Nuclear Factor κB-Dependent Insulin-Like Growth Factor 2 (Igf2) Expression Regulates Synapse Formation and Spine Maturation via Igf2 Receptor Signaling

R. Sprengel, V. Jensen, Ø. Hvalby, 2012, The Journal of Neuroscience.

Sulforaphane targets pancreatic tumour-initiating cells by NF-κB-induced antiapoptotic signalling

P. Altevogt, A. Kolb, M. Büchler, 2008, Gut.

NF-κB-mediated astrocyte dysfunction initiates neurodegeneration.

B. Baumann, M. Lattke, S. Reichel, 2017, Oncotarget.

Dietary polyphenol quercetin targets pancreatic cancer stem cells.

M. Büchler, I. Herr, Wei Zhou, 2010, International journal of oncology.

miR-146a regulates insulin sensitivity via NPR3

P. Fischer-Posovszky, M. Wabitsch, B. Baumann, 2020, Cellular and Molecular Life Sciences.

Transcription Factor RBPJL Is Able to Repress Notch Target Gene Expression but Is Non-Responsive to Notch Activation

F. Oswald, U. Knippschild, J. Gebhardt, 2021, Cancers.

In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8-16-mer Oligomer Species.

A. Ekici, B. Liss, A. Ludolph, 2019, Cell reports.

Long-Term IKK2/NF-κB Signaling in Pancreatic β-Cells Induces Immune-Mediated Diabetes

Harald J. Maier, B. Boehm, T. Wirth, 2014, Diabetes.

Longterm IKK2/NF κB signaling in pancreatic βcells induces immunemediated diabetes mellitus

Harald J. Maier, B. Boehm, T. Wirth, 2013 .

Apoptotic and inflammatory signaling via Fas and tumor necrosis factor receptor I contribute to the development of chest trauma-induced septic acute lung injury

T. Wirth, S. Denk, M. Huber-Lang, 2013, The journal of trauma and acute care surgery.

Murine clusterin: molecular cloning and mRNA localization of a gene associated with epithelial differentiation processes during embryogenesis

L. French, D. Belin, J. Kiss, 1993, The Journal of cell biology.

NF-κB is a critical mediator of post-mitotic senescence in oligodendrocytes and subsequent white matter loss

F. Oswald, P. Walther, T. Wirth, 2023, Molecular Neurodegeneration.

Identification of a novel pro-apoptotic role of NF-κB in the regulation of TRAIL- and CD95-mediated apoptosis of glioblastoma cells

S. Fulda, B. Baumann, K. Debatin, 2012, Oncogene.

Astrocyte-specific IKK2 activation in mice is sufficient to induce neuroinflammation but does not increase susceptibility to MPTP

T. Wirth, B. Baumann, Patrick Oeckl, 2012, Neurobiology of Disease.

Initiation of Dopaminergic Differentiation of Nurr1− Mesencephalic Precursor Cells Depends on Activation of Multiple Mitogen‐Activated Protein Kinase Pathways

T. Wirth, B. Baumann, A. Storch, 2009, Stem cells.

Synergistic activity of sorafenib and sulforaphane abolishes pancreatic cancer stem cell characteristics.

M. Büchler, I. Herr, M. Zöller, 2010, Cancer research.

Characterization of sonic hedgehog as a novel NF- B target gene that promotes NF- B-mediated apoptosis resistance and tumor growth in vivo

B. Baumann, K. Debatin, H. Kasperczyk, 2008 .

RBPJ Deficiency Sensitizes Pancreatic Acinar Cells to KRAS-Mediated Pancreatic Intraepithelial Neoplasia Initiation

M. Guo, F. Oswald, B. Baumann, 2023, Cellular and molecular gastroenterology and hepatology.

Accelerated aging in mice with astrocytic redox imbalance as a consequence of SOD2 deletion

T. Wirth, B. Baumann, M. Tsesmelis, 2023, Aging cell.

The PMN-MDSC – A key player in glucocorticoid resistance following combined physical and psychosocial trauma

H. Gündel, T. Wirth, B. Baumann, 2022, Brain, Behavior, and Immunity.

NF-κB regulates DNA double-strand break repair in conjunction with BRCA1–CtIP complexes

L. Wiesmüller, S. Fulda, B. Baumann, 2011, Nucleic acids research.

Sustained, neuron-specific IKK/NF-κB activation generates a selective neuroinflammatory response promoting local neurodegeneration with aging

T. Wirth, B. Baumann, A. Maqbool, 2013, Molecular Neurodegeneration.

Inhibition of nuclear factor kappaB activation attenuates apoptosis resistance in lymphoid cells.

I. Herr, I. Jeremias, T. Wirth, 1998, Blood.