M. Wynes

发表

IL‐4‐induced macrophage‐derived IGF‐I protects myofibroblasts from apoptosis following growth factor withdrawal

M. Wynes, S. K. Frankel, D. Riches, 2004, Journal of leukocyte biology.

Induction of Macrophage Insulin-Like Growth Factor-I Expression by the Th2 Cytokines IL-4 and IL-131

M. Wynes, D. Riches, 2003, The Journal of Immunology.

And Il-13 Factor-i Expression by the Th2 Cytokines Il-4 Induction of Macrophage Insulin-like Growth

M. Wynes, D. Riches, 2022 .

The mTOR pathway in lung cancer and implications for therapy and biomarker analysis.

F. Hirsch, M. Wynes, S. Ekman, 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Liquid Biopsy for Advanced Non‐Small Cell Lung Cancer (NSCLC): A Statement Paper from the IASLC

Paul Baas, Ignacio I. Wistuba, Robert Pirker, 2018, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors: Guideline From the College of American Pathologists, the International Association for the Study of Lung Cancer, and the Association for Molecular Pathology

Benjamin Solomon, Neal I. Lindeman, Dara L. Aisner, 2018, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Current Status and Future Perspectives on Neoadjuvant Therapy in Lung Cancer

Lawrence H. Schwartz, Donald A. Berry, Janis M. Taube, 2018, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

TNF-α Sensitizes Normal and Fibrotic Human Lung Fibroblasts to Fas-Induced Apoptosis

K. Brown, S. Cha, M. Wynes, 2006 .

Robyn L. Temple-Smolkin, M. Ladanyi, Christina B. Ventura, 2018, Archives of pathology & laboratory medicine.

Reovirus-Induced Apoptosis Is Preceded by Increased Cellular Calpain Activity and Is Blocked by Calpain Inhibitors

R. DeBiasi, K. Tyler, M. Wynes, 1999, Journal of Virology.

Lung Cancer Screening Considerations During Respiratory Infection Outbreaks, Epidemics or Pandemics: An International Association for the Study of Lung Cancer Early Detection and Screening Committee Report

S. Lam, E. Kazerooni, C. Henschke, 2021, Journal of Thoracic Oncology.

Correlation between MET Gene Copy Number by Silver In Situ Hybridization and Protein Expression by Immunohistochemistry in Non-small Cell Lung Cancer

F. Hirsch, R. Dziadziuszko, J. Jassem, 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Lung Cancer: A multidisciplinary Approach to Diagnosis and Management

F. Hirsch, C. Mascaux, M. Wynes, 2010 .

Scientific Advances in Lung Cancer 2015

Kenneth E. Rosenzweig, Hisao Asamura, Annette McWilliams, 2016, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Regulation of chemokine expression by NaCl occurs independently of cystic fibrosis transmembrane conductance regulator in macrophages.

M. Wynes, D. Riches, R. Loi, 2006, The American journal of pathology.

Detection of circulating lung cancer cells with strong thymidylate synthase reactivity in the peripheral blood of a patient with pulmonary adenocarcinoma treated with pemetrexed.

F. Hirsch, T. Gauler, M. Schuler, 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Thymidylate Synthase Protein Expression by IHC and Gene Copy Number by SISH Correlate and Show Great Variability in Non–Small Cell Lung Cancer

F. Hirsch, R. Dziadziuszko, J. Jassem, 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Protein Tyrosine Phosphatase‐N13 Promotes Myofibroblast Resistance to Apoptosis in Idiopathic Pulmonary Fibrosis

A. Thorburn, S. Groshong, L. Ortiz, 2018, American journal of respiratory and critical care medicine.

Preferential activation of the p46 isoform of JNK/SAPK in mouse macrophages by TNF alpha.

E. Chan, M. Wynes, D. Riches, 1997, Proceedings of the National Academy of Sciences of the United States of America.

TNF-alpha sensitizes normal and fibrotic human lung fibroblasts to Fas-induced apoptosis.

K. Brown, S. Cha, M. Wynes, 2006, American journal of respiratory cell and molecular biology.

The role of anaplastic lymphoma kinase inhibitors in the treatment of advanced nonsmall cell lung cancer

F. Hirsch, M. Wynes, M. D'Arcangelo, 2013, Current opinion in oncology.

The International Association for the Study of Lung Cancer Global Survey on Programmed Death-Ligand 1 Testing for NSCLC

N. Le Stang, A. Borczuk, I. Wistuba, 2022, Journal of Thoracic Oncology.

Evaluation of the Role of Mitogen-Activated Protein Kinases in the Expression of Inducible Nitric Oxide Synthase by IFN-γ and TNF-α in Mouse Macrophages

S. Uh, E. Chan, M. Wynes, 1999, The Journal of Immunology.

Transcription of macrophage IGF-I exon 1 is positively regulated by the 5'-untranslated region and negatively regulated by the 5'-flanking region.

M. Wynes, D. Riches, 2005, American journal of physiology. Lung cellular and molecular physiology.

The International Association for the Study of Lung Cancer Consensus Statement on Optimizing Management of EGFR Mutation-Positive Non-Small Cell Lung Cancer: Status in 2016.

D. Yankelevitz, I. Wistuba, R. Herbst, 2016, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Scientific Advances in Thoracic Oncology 2016.

H. Groen, C. Rudin, R. Rami-Porta, 2017, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Increased ALK Gene Copy Number and Amplification are Frequent in Non-small Cell Lung Cancer

S. Serrano, M. Salido, F. Hirsch, 2011, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?

G. Giaccone, M. Krasnow, C. Rudin, 2022 .

Contributions of KRAS and RAL in Non–Small-Cell Lung Cancer Growth and Progression

F. Hirsch, D. Theodorescu, M. Wynes, 2013, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Folylpoly-Glutamate Synthetase Expression Is Associated with Tumor Response and Outcome from Pemetrexed-Based Chemotherapy in Malignant Pleural Mesothelioma

F. Hirsch, T. Gauler, M. Schuler, 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Insulin-like growth factor-1 receptor (IGF-1R) as a biomarker for resistance to the tyrosine kinase inhibitor gefitinib in non-small cell lung cancer

T. Ohira, Koichi Yoshida, N. Ikeda, 2013, Cellular Oncology.

The International Association for the Study of Lung Cancer (IASLC) Global Survey on Molecular Testing in Lung Cancer.

Edward S. Kim, M. Tsuboi, G. Scagliotti, 2019, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

PD‐L1 Immunohistochemistry Comparability Study in Real‐Life Clinical Samples: Results of Blueprint Phase 2 Project

Hui Yu, Keith M. Kerr, Ignacio Wistuba, 2018, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

OA03.03 Phase 2B of Blueprint PD-L1 Immunohistochemistry Assay Comparability Study

A. Nicholson, A. Borczuk, L. Chirieac, 2018, Journal of Thoracic Oncology.

Novel Epidermal Growth Factor Receptor Mutation-Specific Antibodies for Non-small Cell Lung Cancer: Immunohistochemistry as a Possible Screening Method for Epidermal Growth Factor Receptor Mutations

T. Ohira, M. Tsuboi, Koichi Yoshida, 2010, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Review: Predictive and prognostic markers for epidermal growth factor receptor inhibitor therapy in non-small cell lung cancer

Koichi Yoshida, F. Hirsch, M. Wynes, 2009, Therapeutic advances in medical oncology.

International Association for the Study of Lung Cancer (IASLC)

G. Scagliotti, I. Wistuba, C. Swanton, 2019, Annals of Oncology.

Increased Insulin-Like Growth Factor 1 Receptor Protein Expression and Gene Copy Number in Small Cell Lung Cancer

F. Hirsch, R. Dziadziuszko, F. Gaire, 2010, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

IASLC Global Survey on PD-L1 Testing for Non-Small Cell Lung Cancer.

N. Le Stang, A. Nicholson, A. Borczuk, 2021, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Next-generation sequencing identifies and immunohistochemistry confirms a novel crizotinib-sensitive ALK rearrangement in a patient with metastatic non-small-cell lung cancer.

P. Stephens, M. Cronin, F. Hirsch, 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Case Presentation Alk Fusions Are Also Associated with Younger Age Next-generation Sequencing Identifies and Immunohistochemistry Confirms a Novel Crizotinib- Sensitive Alk Rearrangement in a Patient with Metastatic Non–small-cell Lung Cancer

P. Stephens, M. Cronin, F. Hirsch, 2012 .

A Phase I/II Study of Erlotinib in Combination with the Anti-Insulin-Like Growth Factor-1 Receptor Monoclonal Antibody IMC-A12 (Cixutumumab) in Patients with Advanced Non-small Cell Lung Cancer

F. Hirsch, W. Franklin, M. Varella‐Garcia, 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

FGFR1 mRNA and Protein Expression, not Gene Copy Number, Predict FGFR TKI Sensitivity across All Lung Cancer Histologies

F. Hirsch, P. Bunn, R. Dziadziuszko, 2014, Clinical Cancer Research.

Predictive Biomarkers and Personalized Medicine FGFR1 mRNA and Protein Expression, not Gene Copy Number, Predict FGFRTKI Sensitivity across All LungCancer Histologies

F. Hirsch, P. Bunn, R. Dziadziuszko, 2014 .

The Tissue Is the Issue: Personalized Medicine for Non-Small Cell Lung Cancer

F. Hirsch, P. Bunn, D. Gandara, 2010, Clinical Cancer Research.

Tissue Is the Issue : Personalized Medicine R Non-Small Cell Lung Cancer

P. Bunn, D. Gandara, M. Wynes, 2010 .

An International Interpretation Study Using the ALK IHC Antibody D5F3 and a Sensitive Detection Kit Demonstrates High Concordance between ALK IHC and ALK FISH and between Evaluators

M. Dietel, F. Hirsch, E. Schuuring, 2014, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

EGFR Protein Expression in Non–Small Cell Lung Cancer Predicts Response to an EGFR Tyrosine Kinase Inhibitor—A Novel Antibody for Immunohistochemistry or AQUA Technology

Cindy Tran, Toshitaka Nagao, Norihiko Ikeda, 2011, Clinical Cancer Research.

Treatment Guidance for Patients With Lung Cancer During the Coronavirus 2019 Pandemic

G. Scagliotti, E. Smit, A. Dingemans, 2020, Journal of Thoracic Oncology.

Treatment Guidance for Patients With Lung Cancer During the Coronavirus 2019 Pandemic

G. Scagliotti, E. Smit, A. Dingemans, 2020, Journal of Thoracic Oncology.

Robyn L. Temple-Smolkin, M. Ladanyi, Christina B. Ventura, 2018, The Journal of molecular diagnostics : JMD.

Evaluation of the role of mitogen-activated protein kinases in the expression of inducible nitric oxide synthase by IFN-gamma and TNF-alpha in mouse macrophages.

S. Uh, E. Chan, M. Wynes, 1999, Journal of immunology.

Fluorescence in situ hybridization, immunohistochemistry, and next-generation sequencing for detection of EML4-ALK rearrangement in lung cancer.

F. Hirsch, D. Lipson, P. Bunn, 2015, The oncologist.

Lung Cancer Fluorescence In Situ Hybridization , Immunohistochemistry , and Next-Generation Sequencing for Detection of EML 4-ALK Rearrangement in Lung Cancer

F. Hirsch, D. Lipson, P. Bunn, 2015 .

Independent validation test of the vote-counting strategy used to rank biomarkers from published studies.

F. Hirsch, A. Baron, M. Wynes, 2015, Biomarkers in medicine.

A miRNA Panel Predicts Sensitivity of FGFR Inhibitor in Lung Cancer Cell Lines

F. Hirsch, D. Gao, C. Rivard, 2018, Clinical lung cancer.

Fibroblast Growth Factor Receptor 1 as a Putative Therapy Target in Colorectal Cancer

G. Kristiansen, W. Weichert, A. Stenzinger, 2013, Digestion.

Early detection and screening of lung cancer

F. Hirsch, C. Mascaux, M. Wynes, 2010, Expert review of molecular diagnostics.

From Expert Review of Molecular Diagnostics

F. Hirsch, C. Mascaux, M. Wynes, 2010 .

Increased Cell Surface Fas Expression Is Necessary and Sufficient To Sensitize Lung Fibroblasts to Fas Ligation-Induced Apoptosis: Implications for Fibroblast Accumulation in Idiopathic Pulmonary Fibrosis

K. Brown, S. Groshong, M. Wynes, 2011, The Journal of Immunology.

FibrosisAccumulation in Idiopathic Pulmonary Apoptosis: Implications for Fibroblast Fibroblasts to Fas Ligation-Induced Necessary and Sufficient To Sensitize Lung Increased Cell Surface Fas Expression Is

Riches, K. Brown, S. Groshong, 2011 .

Human insulin-like growth factor-IA expression in transgenic mice promotes adenomatous hyperplasia but not pulmonary fibrosis.

M. Wynes, S. K. Frankel, D. Riches, 2005, American journal of physiology. Lung cellular and molecular physiology.

P2.09-24 IASLC Global Survey for Pathologists on PD-L1 Testing for Non-Small Cell Lung Cancer

A. Nicholson, A. Borczuk, Guoan Chen, 2019, Journal of Thoracic Oncology.

IGF-1R as a predictive marker for EGFR TKI (Gefitinib) resistance in Non Small Cell Lung Cancer using IHC and AQUA technology

T. Ohira, Koichi Yoshida, N. Ikeda, 2011 .

Significance of Folate Receptor Alpha and Thymidylate Synthase Protein Expression in Patients with Non–Small-Cell Lung Cancer Treated with Pemetrexed

F. Hirsch, T. Gauler, M. Schuler, 2013, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

International Association for the Study of Lung Cancer Study of Reproducibility in Assessment of Pathologic Response in Resected Lung Cancers After Neoadjuvant Therapy.

M. Kris, I. Wistuba, N. Altorki, 2023, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

The International Association for the Study of Lung Cancer Early Lung Imaging Confederation

P. V. van Ooijen, M. Oudkerk, S. Lam, 2020, JCO clinical cancer informatics.

Novel Epidermal Growth Factor Receptor Mutation-Specific Antibodies for Non-small Cell Lung Cancer: Immunohistochemistry as a Possible Screening Method for Epidermal Growth Factor Receptor Mutations

T. Ohira, M. Tsuboi, Koichi Yoshida, 2010, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Significance of Folate Receptor Alpha and Thymidylate Synthase Protein Expression in Patients with Non–Small-Cell Lung Cancer Treated with Pemetrexed

T. Gauler, M. Schuler, M. Wynes, 2013, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

FGFR1 mRNA and Protein Expression, not Gene Copy Number, Predict FGFR TKI Sensitivity across All Lung Cancer Histologies

P. Bunn, R. Dziadziuszko, D. Gao, 2014, Clinical Cancer Research.

Liquid Biopsy for Advanced Non-Small Cell Lung Cancer: A Consensus Statement from The International Association for the Study of Lung Cancer (IASLC).

H. Wakelee, L. Sequist, M. Diehn, 2021, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?

M. Krasnow, J. Minna, P. Massion, 2016, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

And Il-13 Factor-i Expression by the Th2 Cytokines Il-4 Induction of Macrophage Insulin-like Growth

M. Wynes, D. Riches, 2022 .

Insulin-like growth factor-1 receptor (IGF-1R) as a biomarker for resistance to the tyrosine kinase inhibitor gefitinib in non-small cell lung cancer

T. Ohira, Koichi Yoshida, N. Ikeda, 2013, Cellular Oncology.

Access to Cancer Specialist Care and Treatment in Patients With Advanced Stage Lung Cancer

S. Ramalingam, H. Borghaei, M. Wynes, 2017, Clinical lung cancer.