K. Shimoke

发表

Prevention of endoplasmic reticulum stress-induced cell death by brain-derived neurotrophic factor in cultured cerebral cortical neurons

K. Shimoke, Takahiro Utsumi, Soichiro Kishi, 2004, Brain Research.

Nerve growth factor prevents 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine‐induced cell death via the Akt pathway by suppressing caspase‐3‐like activity using PC12 cells: Relevance to therapeutical application for parkinson's disease

K. Shimoke, H. Chiba, K Shimoke, 2001, Journal of neuroscience research.

Differences in survival‐promoting effects and intracellular signaling properties of BDNF and IGF‐1 in cultured cerebral cortical neurons

K. Shimoke, T. Ikeuchi, M. Yamada, 2001, Journal of neurochemistry.

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine has a transient proliferative effect on PC12h cells and nerve growth factor additively promotes this effect: possible involvement of distinct mechanisms of activation of MAP kinase family proteins.

K. Shimoke, M. Kudo, Motoshige Kudo, 2002, Brain research. Developmental brain research.

MPTP-induced reactive oxygen species promote cell death through a gradual activation of caspase-3 without expression of GRP78/Bip as a preventive measure against ER stress in PC12 cells.

K. Shimoke, M. Kudo, T. Ikeuchi, 2003, Life sciences.

Inhibition of phosphatidylinositol 3-kinase activity elevates C-jun N-terminal kinase activity in apoptosis of cultured cerebellar granule neurons

K. Shimoke, T. Ikeuchi, M. Yamada, 1998, Neuroscience Research.

Analysis of the role of nerve growth factor in promoting cell survival during endoplasmic reticulum stress in PC12 cells.

K. Shimoke, Harue Sasaya, T. Ikeuchi, 2011, Methods in enzymology.

Nicotine suppresses tunicamycin-induced, but not thapsigargin-induced, expression of GRP78 during ER stress-mediated apoptosis in PC12 cells.

K. Shimoke, Takahiro Utsumi, Harue Sasaya, 2008, Journal of biochemistry.

Molecular mechanism of nur77 gene expression and downstream target genes in the early stage of forskolin-induced differentiation in PC12 cells

K. Shimoke, R. Takahashi, Ryosuke Yamazoe, 2020, Scientific Reports.

Low-molecular-weight compounds having neurotrophic activity in cultured PC12 cells and neurons.

K. Shimoke, Harue Sasaya, T. Ikeuchi, 2011, Journal of biochemistry.

Nerve growth factor attenuates 2-deoxy-d-glucose-triggered endoplasmic reticulum stress-mediated apoptosis via enhanced expression of GRP78

K. Shin‐ya, K. Shimoke, Soichiro Kishi, 2010, Neuroscience Research.

[Apoptosis-inducing and -preventing signal transduction pathways in cultured cerebellar granule neurons].

K. Shimoke, T. Ikeuchi, M. Yamada, 1998, Human cell.

p-Nonylphenol induces endoplasmic reticulum stress-mediated apoptosis in neuronally differentiated PC12 cells

K. Shimoke, Soichiro Kishi, T. Ikeuchi, 2008, Neuroscience Letters.

Synthetic lipid products of PI3‐kinase which are added to culture medium prevent low K+‐induced apoptosis of cerebellar granule neurons via Akt kinase activation

K. Shimoke, T. Ikeuchi, M. Yamada, 1998, FEBS letters.

ER stress is the initial response to polyglutamine toxicity in PC12 cells.

K. Shimoke, T. Ikeuchi, M. Yoshizumi, 2008, Biochemical and biophysical research communications.

Genomic Control of Upregulation of GRP78 Expression for Promotion of Neurite Elongation and Attenuation of Cell Death via PKA-Mediated Signaling in PC12 Cells

K. Shimoke, Ryosuke Yamazoe, Hiroki Aoyama, 2015 .

Apoptosis-inducing activity of endocrine-disrupting chemicals in cultured PC12 cells

K. Shimoke, Harue Sasaya, T. Ikeuchi, 2012 .

NGF-induced phosphatidylinositol 3-kinase signaling pathway prevents thapsigargin-triggered ER stress-mediated apoptosis in PC12 cells

K. Shimoke, Takahiro Utsumi, Soichiro Kishi, 2005, Neuroscience Letters.

Synthesis and cancer antiproliferative activity of new histone deacetylase inhibitors: hydrophilic hydroxamates and 2-aminobenzamide-containing derivatives.

K. Shimoke, T. Ikeuchi, S. Uesato, 2006, European journal of medicinal chemistry.

New Orally Bioavailable 2-aminobenzamide-type Histone Deacetyase Inhibitor Promotes Neurite Outgrowth via histone H3 Modification in PC12 cells: a Possible Therapeutic Candidate for Neuronal Diseases

K. Shimoke, T. Ikeuchi, S. Uesato, 2011 .

The histone deacetylase inhibitor trichostatin A induces neurite outgrowth in PC12 cells via the epigenetically regulated expression of the nur77 gene

K. Shimoke, T. Ikeuchi, Ryosuke Yamazoe, 2014, Neuroscience Research.

Histone Deacetylase Inhibitor for Neurodegenerative Diseases: A Possible Medicinal Strategy by Prevention of ER Stress-Mediated Apoptosis and Induction of Neurite Elongation

K. Shimoke, T. Ikeuchi, S. Uesato, 2013 .

Histone Deacetylase Inhibitor for Neurodegenerative Diseases: A Possible Medicinal Strategy by Prevention of ER Stress-Mediated Apoptosis and Neurite Elongation

K. Shimoke, T. Ikeuchi, S. Uesato, 2013 .

Dibutyryl-cAMP up-regulates nur77 expression via histone modification during neurite outgrowth in PC12 cells.

K. Shimoke, Harue Sasaya, T. Ikeuchi, 2010, Journal of biochemistry.

ERK1/2 are involved in low potassium-induced apoptotic signaling downstream of ASK1-p38 MAPK pathway in cultured cerebellar granule neurons

K. Shimoke, T. Ikeuchi, M. Yamada, 2005, Brain Research.

Apoptosis-signal regulating kinase-1 is involved in the low potassium-induced activation of p38 mitogen-activated protein kinase and c-Jun in cultured cerebellar granule neurons.

H. Ichijo, K. Shimoke, T. Ikeuchi, 2003, Journal of biochemistry.

Comparison of inhibitory effects of brain-derived neurotrophic factor and insulin-like growth factor on low potassium-induced apoptosis and activation of p38 MAPK and c-Jun in cultured cerebellar granule neurons.

K. Shimoke, T. Ikeuchi, M. Yamada, 2003, Brain research. Molecular brain research.

Signaling pathways and survival effects of BDNF and NT-3 on cultured cerebellar granule cells.

K. Shimoke, M. Yamada, H. Hatanaka, 1996, Brain research. Developmental brain research.

Involvement of phosphatidylinositol-3 kinase in prevention of low K(+)-induced apoptosis of cerebellar granule neurons.

K. Shimoke, T. Ikeuchi, T. Kubo, 1997, Brain research. Developmental brain research.

Protective effect of nicotine on tunicamycin-induced apoptosis of PC12h cells

K. Shimoke, Takahiro Utsumi, Soichiro Kishi, 2004, Neuroscience Letters.

Nerve growth factor attenuates endoplasmic reticulum stress-mediated apoptosis via suppression of caspase-12 activity.

K. Shimoke, Soichiro Kishi, M. Kudo, 2004, Journal of biochemistry.

Appearance of Nuclear-sorted Caspase-12 Fragments in Cerebral Cortical and Hippocampal Neurons in Rats Damaged by Autologous Blood Clot Embolic Brain Infarctions

K. Shimoke, M. Kudo, T. Ikeuchi, 2011, Cellular and Molecular Neurobiology.

Purification, Characterization, and Overexpression of Psychrophilic and Thermolabile Malate Dehydrogenase of a Novel Antarctic Psychrotolerant, Flavobacterium frigidimaris KUC-1

Tadao Oikawa, Koji Shimoke, Toshihiko Ikeuchi, 2005, Bioscience, biotechnology, and biochemistry.

Epigenetic Regulation by Bisphenol A as a Neuronal Morphogen

K. Shimoke, Ryosuke Yamazoe, Hiroki Maruoka, 2017 .

Subtypes of neuronal nicotinic acetylcholine receptors involved in nicotine-induced phosphorylation of extracellular signal-regulated protein kinase in PC12h cells

K. Shimoke, T. Ikeuchi, M. Yoshizumi, 2006, Neuroscience Letters.

Endocrine Disrupting Chemicals - Inducers of Epigenetic Gene Expression and Enhancers of Cell Death in Neurons

K. Shimoke, 2015 .

Inhibition of phosphatidylinositol 3-kinase activity elevates C-jun N-terminal kinase activity in apoptosis of cultured cerebellar granule neurons

K. Shimoke, T. Ikeuchi, M. Yamada, 1998, Neuroscience Research.

Mechanisms of Neurotrophic Activities via Low-molecular-weight Compounds: Post-transcriptional Regulation in PC12 Cells and Neurons

K. Shimoke, Hiroki Maruoka, 2013 .