D. Lauro

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Increased O‐glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic β‐cells

P. Marchetti, M. Ranalli, G. Sesti, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The common Arg972 polymorphism in insulin receptor substrate‐1 causes apoptosis of human pancreatic islets

Patrizia Borboni, Marco Ranalli, Lorella Marselli, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Peroxiredoxin 6 Is a Key Antioxidant Enzyme in Modulating the Link between Glycemic and Lipogenic Metabolism

D. Lauro, M. Scioli, A. Orlandi, 2019, Oxidative medicine and cellular longevity.

A systems medicine clinical platform for understanding and managing non- communicable diseases.

Frederick B. Marcus, P. Rossini, C. Auffray, 2014, Current pharmaceutical design.

Serum glucocorticoid inducible kinase (SGK)-1 protects endothelial cells against oxidative stress and apoptosis induced by hyperglycaemia

M. Federici, D. Lauro, D. Della-Morte, 2015, Acta Diabetologica.

Phosphorylation of GATA2 by Akt Increases Adipose Tissue Differentiation and Reduces Adipose Tissue–Related Inflammation: A Novel Pathway Linking Obesity to Atherosclerosis

M. Federici, M. Cardellini, D. Lauro, 2005, Circulation.

NK Cell Inflammation in the Clinical Outcome of Colorectal Carcinoma

D. Lauro, A. Venditti, F. Buccisano, 2015, Front. Med..

Increased abundance of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of obese subjects is correlated with in vivo insulin sensitivity.

G. Sesti, M. Federici, D. Lauro, 1998, The Journal of clinical endocrinology and metabolism.

NK cells and T cells cooperate during the clinical course of colorectal cancer

L. Terracciano, S. Ferrone, D. Lauro, 2014, Oncoimmunology.

Asthma and COPD in an Italian adult population: role of BMI considering the smoking habit.

M. Cazzola, D. Lauro, C. Cricelli, 2013, Respiratory medicine.

Insulin and Exendin-4 Reduced Mutated Huntingtin Accumulation in Neuronal Cells

D. Lauro, D. Della-Morte, N. Di Daniele, 2020, Frontiers in Pharmacology.

The Gly-->Arg972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells.

D. Accili, G. Sesti, M. Federici, 2000, The Journal of clinical endocrinology and metabolism.

The role of epsilon PKC in acute and chronic diseases: Possible pharmacological implications of its modulators.

F. Guadagni, P. Abete, D. Lauro, 2016, Pharmacological research.

Drug interactions of direct oral anticoagulants in elderly patients with cardiometabolic diseases

D. Lauro, D. Della-Morte, N. Di Daniele, 2021, Current research in pharmacology and drug discovery.

The sulfonylurea glimepiride regulates intracellular routing of the insulin-receptor complexes through their interaction with specific protein kinase C isoforms.

G. Sesti, M. Federici, D. Lauro, 2001, Molecular pharmacology.

Chronic hyperglycemia impairs insulin secretion by affecting insulin receptor expression, splicing, and signaling in RIN β‐cell line and human islets of Langerhans

G. Sesti, F. Bertuzzi, F. Andreozzi, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Deterioration of glucose homeostasis in type 2 diabetic patients one year after beginning of statins therapy.

M. Quon, M. Federici, D. Lauro, 2012, Atherosclerosis.

Early vascular and metabolic effects of rosuvastatin compared with simvastatin in patients with type 2 diabetes.

D. Lauro, P. Sbraccia, M. Tesauro, 2010, Atherosclerosis.

Relationship between plasma free fatty acids and uncoupling protein‐3 gene expression in skeletal muscle of obese subjects: in vitro evidence of a causal link

G. Silecchia, M. Federici, D. Lauro, 2002, Clinical endocrinology.

Expression of Insulin/IGF-I Hybrid Receptors Is Increased in Skeletal Muscle of Patients With Chronic Primary Hyperinsulinemia

G. Sesti, M. Federici, D. Lauro, 1998, Diabetes.

TIMP3 Overexpression in Macrophages Protects From Insulin Resistance, Adipose Inflammation, and Nonalcoholic Fatty Liver Disease in Mice

S. Menini, P. Gentileschi, O. Schillaci, 2012, Diabetes.

Timp3 deficiency in insulin receptor-haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-alpha.

D. Accili, R. Khokha, David C. Lee, 2005, The Journal of clinical investigation.

Mice Heterozygous for Tumor Necrosis Factor-α Converting Enzyme Are Protected From Obesity-Induced Insulin Resistance and Diabetes

M. Federici, D. Lauro, R. Lauro, 2007, Diabetes.

FGF-2b and h-PL Transform Duct and Non-Endocrine Human Pancreatic Cells into Endocrine Insulin Secreting Cells by Modulating Differentiating Genes

M. Bugliani, P. Marchetti, D. Lauro, 2017, International journal of molecular sciences.

Increased expression of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of noninsulin-dependent diabetes mellitus subjects.

G. Sesti, M. Federici, D. Lauro, 1996, The Journal of clinical investigation.

FCγ Chimeric Receptor-Engineered T Cells: Methodology, Advantages, Limitations, and Clinical Relevance

S. Ferrone, D. Lauro, A. Venditti, 2017, Front. Immunol..

T lymphocytes engineered to express a CD16-chimeric antigen receptor redirect T-cell immune responses against immunoglobulin G-opsonized target cells.

D. Lauro, C. Palumbo, Maria Michela D’Aloia, 2016, Cytotherapy.

Long-term observational study on the impact of GLP-1R agonists on lung function in diabetic patients.

M. Cazzola, D. Lauro, L. Calzetta, 2019, Respiratory medicine.

High glucose enhances responsiveness of human airways smooth muscle via the Rho/ROCK pathway.

M. Cazzola, D. Lauro, L. Calzetta, 2012, American journal of respiratory cell and molecular biology.

Occult impaired glucose regulation in patients with atherosclerosis is associated to the number of affected vascular districts and inflammation.

N. Marx, M. Federici, M. Cardellini, 2010, Atherosclerosis.

Adiponectin Isoforms in Elderly Patients with or without Coronary Artery Disease

M. Federici, D. Lauro, R. Lauro, 2010, Journal of the American Geriatrics Society.

Mechanisms of impaired bone strength in type 1 and 2 diabetes.

D. Lauro, R. Nuti, L. Gennari, 2010, Nutrition, metabolism, and cardiovascular diseases : NMCD.

Omental adipose tissue fibrosis and insulin resistance in severe obesity

P. Gentileschi, M. Federici, M. Cardellini, 2015, Nutrition & Diabetes.

Activation of Peripheral Blood Mononuclear Cells and Leptin Secretion: New Potential Role of Interleukin-2 and High Mobility Group Box (HMGB)1

D. Lauro, R. Lauro, D. Della-Morte, 2021, International journal of molecular sciences.

Reduced risk of COVID-19 hospitalization in asthmatic and COPD patients: a benefit of inhaled corticosteroids?

D. Lauro, A. Chetta, L. Calzetta, 2020, Expert review of respiratory medicine.

The Impact of Vegan Diet in the Prevention and Treatment of Type 2 Diabetes: A Systematic Review

D. Lauro, D. Della-Morte, F. Pacifici, 2021, Nutrients.

Pharmacogenomics and pharmacogenetics of thiazolidinediones: role in diabetes and cardiovascular risk factors.

Maria Laura De Marchis, F. Guadagni, P. Abete, 2014, Pharmacogenomics.

CD16‐158‐valine chimeric receptor T cells overcome the resistance of KRAS‐mutated colorectal carcinoma cells to cetuximab

S. Ferrone, D. Lauro, M. Roselli, 2020, International journal of cancer.

CD16-158-Valine Chimeric Receptor T Cells Overcome the Resistance of KRAS-mutated Colorectal Carcinoma Cells to Cetuximab

S. Ferrone, D. Lauro, M. Roselli, 2019, bioRxiv.

Fish oil supplementation improves endothelial function in normoglycemic offspring of patients with type 2 diabetes.

M. Quon, M. Federici, D. Lauro, 2009, Atherosclerosis.

Glucagon-Like Peptide 1 Receptor: A Novel Pharmacological Target for Treating Human Bronchial Hyperresponsiveness.

M. Cazzola, D. Lauro, F. Facciolo, 2016, American journal of respiratory cell and molecular biology.

Foot Revascularization Avoids Major Amputation in Persons with Diabetes and Ischaemic Foot Ulcers

D. Lauro, A. Bellia, L. Giurato, 2021, Journal of clinical medicine.

Metabolic characteristics in patients with COVID-19 and no-COVID-19 interstitial pneumonia with mild-to-moderate symptoms and similar radiological severity

M. Federici, M. Cardellini, D. Lauro, 2021, Nutrition, Metabolism and Cardiovascular Diseases.

Vascular, metabolic, and inflammatory abnormalities in normoglycemic offspring of patients with type 2 diabetes mellitus.

A. Scuteri, M. Quon, J. Panza, 2007, Metabolism: clinical and experimental.

Obesity and kidney disease: Beyond the hyperfiltration

D. Lauro, N. Di Daniele, S. Nisticò, 2016, International journal of immunopathology and pharmacology.

The possible role of glutathione-S-transferase activity in diabetic nephropathy

D. Lauro, V. Rovella, N. Di Daniele, 2015, International journal of immunopathology and pharmacology.

Tumor Necrosis Factor-α Antagonism Improves Vasodilation During Hyperinsulinemia in Metabolic Syndrome

M. Quon, D. Lauro, V. Rovella, 2008, Diabetes Care.

The gut microbiome as possible mediator of the beneficial effects of very low calorie ketogenic diet on type 2 diabetes and obesity: a narrative review

D. Lauro, F. Strollo, A. Bellia, 2022, Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity.

Impaired glucose tolerance in mice with a targeted impairment of insulin action in muscle and adipose tissue

Y. Kido, D. Accili, D. Lauro, 1998, Nature Genetics.

EGFR GLIOBLASTOMA STEM CELLS TARGETING BY CD16158V CHIMERIC RECEPTOR T CELLS AND CETUXIMAB

D. Lauro, M. Roselli, A. Venditti, 2021, Annals of Research in Oncology.

HLA‐DRB1*13:01 allele in the genetic susceptibility to colorectal carcinoma

D. Lauro, A. Orlandi, O. Buonomo, 2015, International journal of cancer.

Expression of kinase-inactive mutant insulin receptors does not rescue insulin receptor-deficient mice from perinatal death

Y. Kido, D. Accili, D. Lauro, 1999, Diabetologia.

Influence of Nutritional Status and Physical Exercise on Immune Response in Metabolic Syndrome

E. Padua, D. Lauro, A. Feraco, 2022, Nutrients.

Mitochondrial DNA Copy Number in Peripheral Blood Is Reduced in Type 2 Diabetes Patients with Polyneuropathy and Associated with a MIR499A Gene Polymorphism.

G. Novelli, P. Borgiani, D. Lauro, 2020, DNA and cell biology.

Insulin-Dependent Activation of Endothelial Nitric Oxide Synthase Is Impaired by O-Linked Glycosylation Modification of Signaling Proteins in Human Coronary Endothelial Cells

G. Sesti, M. Federici, D. Lauro, 2002, Circulation.

Relationship between body composition, body mass index and bone mineral density in a large population of normal, osteopenic and osteoporotic women

A. Bazzocchi, D. Lauro, U. Tarantino, 2011, La radiologia medica.

Proposed Tandem Effect of Physical Activity and Sirtuin 1 and 3 Activation in Regulating Glucose Homeostasis

F. Guadagni, P. Abete, Chiara Salimei, 2019, International journal of molecular sciences.

Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential

G. Sesti, M. Federici, D. Lauro, 2000, Diabetes/metabolism research and reviews.

in IRS-1 impairs insulin secretion in pancreatic β cells

D. Accili, G. Sesti, M. Federici, 1999 .

G 972 R IRS-1 Variant Impairs Insulin Regulation of Endothelial Nitric Oxide Synthase in Cultured Human Endothelial Cells

G. Pellegrini, G. Sesti, M. Federici, 2004 .

Genetics of type 2 diabetes: insight from targeted mouse mutants.

Y. Kido, D. Accili, J. Nakae, 2001, Current molecular medicine.

Generalized impairment of vasodilator reactivity during hyperinsulinemia in patients with obesity-related metabolic syndrome.

D. Lauro, O. Porzio, V. Rovella, 2010, American journal of physiology. Endocrinology and metabolism.

The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes.

G. Sesti, F. Andreozzi, M. Federici, 2004, Diabetes.

Polymorphisms of the insulin receptor substrate-2 in patients with type 2 diabetes.

G. Sesti, M. Federici, D. Lauro, 2003, The Journal of clinical endocrinology and metabolism.

Increased abundance of insulin/IGF-I hybrid receptors in adipose tissue from NIDDM patients

G. Sesti, M. Federici, D. Lauro, 1997, Molecular and Cellular Endocrinology.

Polyphenols and Ischemic Stroke: Insight into One of the Best Strategies for Prevention and Treatment

P. Abete, C. Ricordi, D. Lauro, 2021, Nutrients.

What is the actual epidemiology of familial hypercholesterolemia in Italy? Evidence from a National Primary Care Database.

F. Lapi, M. Federici, D. Lauro, 2016, International journal of cardiology.

Increased abundance of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of obese subjects is correlated with in vivo insulin sensitivity.

G. Sesti, M. Federici, D. Lauro, 1998, The Journal of clinical endocrinology and metabolism.

Drug interactions in users of tablet vs. oral liquid levothyroxine formulations: a real-world evidence study in primary care

F. Lapi, D. Lauro, G. Medea, 2018, Endocrine.

Genotypic and phenotypic heterogeneity in Streptococcus mutans isolated from diabetic patients in Rome, Italy

D. Lauro, A. De, L. A. Vitali, 2016, SpringerPlus.

Below-the-ankle arterial disease: a new marker of coronary artery disease in patients with diabetes and foot ulcers

D. Lauro, A. Bellia, L. Giurato, 2022, Acta Diabetologica.

Ghrelin has novel vascular actions that mimic PI 3-kinase-dependent actions of insulin to stimulate production of NO from endothelial cells.

Hui Chen, M. Quon, D. Lauro, 2007, American journal of physiology. Endocrinology and metabolism.

Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay

S. Menini, I. Arisi, D. Accili, 2013, EMBO molecular medicine.

SGK-1 protects kidney cells against apoptosis induced by ceramide and TNF-α

D. Noto, M. Federici, D. Lauro, 2015, Cell Death and Disease.

Liver protein profiles in insulin receptor-knockout mice reveal novel molecules involved in the diabetes pathophysiology.

A. Urbani, M. Federici, D. Lauro, 2015, American journal of physiology. Endocrinology and metabolism.

Sildenafil Reduces Insulin-Resistance in Human Endothelial Cells

M. Federici, D. Lauro, A. Fabbri, 2011, PloS one.

The Gly 3 Arg 972 Amino Acid Polymorphism in Insulin Receptor Substrate-1 Affects Glucose Metabolism in Skeletal Muscle Cells*

D. Accili, G. Sesti, M. Federici, 2000 .

Pioglitazone improves endothelial and adipose tissue dysfunction in pre-diabetic CAD subjects.

M. Federici, M. Cardellini, D. Lauro, 2011, Atherosclerosis.

Evidence for Glucose/Hexosamine In Vi v o Regulation of Insulin/IGF-I Hybrid R e c e p t o r A s s e m b l y

G. Sesti, M. Federici, D. Lauro, 1999 .

Iron status in obesity: An independent association with metabolic parameters and effect of weight loss.

M. Federici, D. Lauro, P. Sbraccia, 2015, Nutrition, metabolism, and cardiovascular diseases : NMCD.

The diagnostic usefulness of the combined COMPASS 31 questionnaire and electrochemical skin conductance for diabetic cardiovascular autonomic neuropathy and diabetic polyneuropathy

D. Lauro, V. Spallone, V. Izzo, 2020, Journal of the peripheral nervous system : JPNS.

Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial.

Debra F. Weinstein, Michael G. Miller, M. A. Ferreira, 2019, Lancet.

Morning blood pressure surge is associated with autonomic neuropathy and peripheral vascular disease in patients with diabetes

D. Lauro, V. Spallone, R. Morganti, 2019, Journal of Human Hypertension.

The New Role of SGLT2 Inhibitors in the Management of Heart Failure: Current Evidence and Future Perspective

D. Lauro, F. Barillà, N. Di Daniele, 2022, Pharmaceutics.

Increased expression of low-affinity insulin receptor isoform and insulin/insulin-like growth factor-I hybrid receptors in term placenta from insulin-resistant women with gestational hypertension

G. Sesti, M. Federici, D. Lauro, 1996, Diabetologia.

Human placental lactogen (hPL-A) activates signaling pathways linked to cell survival and improves insulin secretion in human pancreatic islets

F. Bertuzzi, M. Federici, D. Lauro, 2011, Islets.

Ghrelin Restores the Endothelin 1/Nitric Oxide Balance in Patients With Obesity-Related Metabolic Syndrome

D. Lauro, V. Rovella, N. Di Daniele, 2009, Hypertension.

Peroxiredoxin6, a Multitask Antioxidant Enzyme Involved in the Pathophysiology of Chronic Noncommunicable Diseases.

D. Lauro, R. Lauro, N. Di Daniele, 2018, Antioxidants & redox signaling.

In vitro elimination of epidermal growth factor receptor‐overexpressing cancer cells by CD32A‐chimeric receptor T cells in combination with cetuximab or panitumumab

S. Ferrone, D. Lauro, A. Venditti, 2019, International journal of cancer.

Elimination of Egfr-Overexpressing Cancer Cells by CD32 Chimeric Receptor T Cells in Combination with Cetuximab or Panitumumab

S. Ferrone, D. Lauro, A. Venditti, 2019, bioRxiv.

Molecular and Functional Characterization of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP-38)/Vasoactive Intestinal Polypeptide Receptors in Pancreatic β-Cells and Effects of PACAP-38 on Components of the Insulin Secretory System1.

G. Sesti, M. Federici, D. Lauro, 1999, Endocrinology.

Molecular and functional characterization of pituitary adenylate cyclase-activating polypeptide (PACAP-38)/vasoactive intestinal polypeptide receptors in pancreatic beta-cells and effects of PACAP-38 on components of the insulin secretory system.

G. Sesti, M. Federici, D. Lauro, 1999, Endocrinology.

The effects of pregnancy steroids on adaptation of beta cells to pregnancy involve the pancreatic glucose sensor glucokinase.

G. Federici, G. Sesti, D. Lauro, 1997, The Journal of endocrinology.

The gut microbiome as possible mediator of the beneficial effects of very low calorie ketogenic diet on type 2 diabetes and obesity: a narrative review

D. Lauro, F. Strollo, A. Bellia, 2022, Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity.

Position Statement on the management of continuous subcutaneous insulin infusion (CSII): The Italian Lazio experience

D. Lauro, P. Pozzilli, S. Frontoni, 2016, Journal of diabetes.

Peroxiredoxin 6 Modulates Insulin Secretion and Beta Cell Death via a Mitochondrial Dynamic Network

F. Ciccosanti, G. Fimia, D. Lauro, 2022, Frontiers in Endocrinology.

Effect of Subclinical Hypothyroidism and Obesity on Whole-Body and Regional Bone Mineral Content

D. Lauro, A. Bertoli, A. De Lorenzo, 2002, Hormone Research in Paediatrics.

Distribution of insulin/insulin-like growth factor-I hybrid receptors in human tissues

G. Sesti, M. Federici, D. Lauro, 1997, Molecular and Cellular Endocrinology.

Insulin resistance and increased intimal medial thickness in glucose tolerant offspring of type 2 diabetic subjects carrying the D298D genotype of endothelial nitric oxide synthase.

G. Sesti, M. Federici, M. Cardellini, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Upregulation of serum and glucocorticoid-regulated kinase 1 exacerbates brain injury and neurological deficits after cardiac arrest.

D. Lauro, D. Della-Morte, D. Pastore, 2020, American journal of physiology. Heart and circulatory physiology.

Identification of multipotent cytotrophoblast cells from human first trimester chorionic villi.

G. Cortese, G. Citro, G. Novelli, 2009, Cloning and stem cells.

A Survey of Autoantibodies to Self Antigens in Graves' Disease Patients with Thyroid-Associated Ophthalmopathy

D. Lauro, A. Bertoli, R. Bei, 2013 .

Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with metformin (TOSCA.IT): a randomised, multicentre trial.

M. Boemi, E. Bonora, A. Gnasso, 2017, The lancet. Diabetes & endocrinology.

Clinical scoring systems for the risk of cardiovascular autonomic neuropathy in type 1 and type 2 diabetes: A simple tool

D. Lauro, V. Spallone, G. Seminara, 2022, Journal of the peripheral nervous system : JPNS.

Hypocalcemia is associated with adverse outcomes in patients hospitalized with COVID-19

D. Lauro, P. Rogliani, N. Di Daniele, 2022, Endocrine.

Age-Dependent Levels of Protein Kinase Cs in Brain: Reduction of Endogenous Mechanisms of Neuroprotection

F. Guadagni, P. Abete, D. Lauro, 2019, International journal of molecular sciences.

Effects of parasitic infection and reproduction on corticosterone plasma levels in Galápagos land iguanas, Conolophus marthae and C. subcristatus

D. Lauro, G. Sancesario, S. Bernardini, 2017, Ecology and evolution.

Citrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells while improving endothelial function and reducing inflammatory markers in patients with metabolic syndrome.

Hui Chen, Davide Lauro, R. Muniyappa, 2011, The Journal of clinical endocrinology and metabolism.

HLA class II antigen expression in colorectal carcinoma tumors as a favorable prognostic marker.

L. Terracciano, C. Ferrone, S. Ferrone, 2014, Neoplasia.

The Gly 972 ® Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic b cells

D. Accili, G. Sesti, M. Federici, 2018 .

Insulin Receptor β-Subunit Haploinsufficiency Impairs Hippocampal Late-Phase LTP and Recognition Memory

N. Mercuri, M. Pignatelli, M. D’Amelio, 2012, NeuroMolecular Medicine.

The Arg972 variant in insulin receptor substrate-1 is associated with an atherogenic profile in offspring of type 2 diabetic patients.

G. Sesti, M. Federici, M. Cardellini, 2003, The Journal of clinical endocrinology and metabolism.

Defects of the insulin receptor substrate (IRS) system in human metabolic disorders

G. Sesti, M. Federici, D. Lauro, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Diabetic peripheral neuropathic pain is a stronger predictor of depression than other diabetic complications and comorbidities

G. Marfia, D. Lauro, V. Spallone, 2016, Diabetes & vascular disease research.

Tyrosol May Prevent Obesity by Inhibiting Adipogenesis in 3T3-L1 Preadipocytes

P. Abete, Chiara Salimei, D. Lauro, 2020, Oxidative medicine and cellular longevity.

Molecular mechanism of insulin resistance in type 2 diabetes mellitus: role of the insulin receptor variant forms

G. Sesti, M. Federici, D. Lauro, 2001, Diabetes/metabolism research and reviews.

The Arg972 variant in insulin receptor substrate-1 is associated with an increased risk of secondary failure to sulfonylurea in patients with type 2 diabetes.

A. Gnasso, G. Sesti, F. Andreozzi, 2004, Diabetes care.

The Arg 972 Variant in Insulin Receptor Substrate-1 Is Associated With an Increased Risk of Secondary Failure to Sulfonylurea in Patients With Type 2 Diabetes

A. Gnasso, G. Sesti, F. Andreozzi, 2004 .

Transgenic mice overexpressing human G972R IRS-1 show impaired insulin action and insulin secretion.

G. Sesti, F. Bosch, M. Federici, 2008, Journal of cellular and molecular medicine.

The Gly972-->Arg IRS-1 variant is associated with type 1 diabetes in continental Italy.

L. Nisticò, G. Sesti, M. Federici, 2003, Diabetes.

Sirtuins and Cancer: Role in the Epithelial-Mesenchymal Transition

F. Guadagni, D. Lauro, D. Della-Morte, 2016, Oxidative medicine and cellular longevity.

Association between a MIR499A polymorphism and diabetic neuropathy in type 2 diabetes.

G. Novelli, P. Borgiani, D. Lauro, 2018, Journal of diabetes and its complications.

Suboptimal use of statins for secondary cardiovascular prevention: a “planetary” issue

D. Lauro, D. Della-Morte, A. Bellia, 2017, Internal and Emergency Medicine.

Effectiveness of adherence to lipid lowering therapy on LDL-cholesterol in patients with very high cardiovascular risk: A real-world evidence study in primary care.

F. Lapi, D. Lauro, G. Medea, 2017, Atherosclerosis.

HLA Class II Antigen Expression in Colorectal Carcinoma Tumors as a Favorable Prognostic Marker 1 , 2

L. Terracciano, C. Ferrone, S. Ferrone, 2014 .

Impact of VEGF gene polymorphisms in elderly cancer patients: clinical outcome and toxicity.

F. Guadagni, D. Lauro, S. Riondino, 2015, Pharmacogenomics.

The ENPP1 Q121 Variant Predicts Major Cardiovascular Events in High-Risk Individuals

M. Copetti, C. Zoccali, M. Federici, 2011, Diabetes.

The \ ( ENPP 1 \ ) Q 121 Variant Predicts Major Cardiovascular Events in High-Risk Individuals

M. Copetti, C. Zoccali, M. Federici, 2011 .

Low level of plasminogen increases risk for mortality in COVID-19 patients

S. Bonassi, C. Ricordi, D. Lauro, 2021, Cell Death & Disease.

Evidence for glucose/hexosamine in vivo regulation of insulin/IGF-I hybrid receptor assembly.

G. Sesti, M. Federici, D. Lauro, 1999, Diabetes.

Linked Glycosylation Modification of Signaling Proteins in Human Coronary Insulin-Dependent Activation of Endothelial Nitric Oxide Synthase Is Impaired

G. Sesti, M. Federici, D. Lauro, 2002 .

Effects of switching from NPH insulin to insulin glargine in patients with type 2 diabetes: the retrospective, observational LAUREL study in Italy

D. Lauro, R. Lauro, A. Bellia, 2014, Acta Diabetologica.

An overview of pancreatic beta-cell defects in human type 2 diabetes: Implications for treatment

P. Marchetti, D. Lauro, F. Purrello, 2008, Regulatory Peptides.

Insulin autoimmune syndrome in an Argentine woman taking α-lipoic acid: A case report and review of the literature

D. Lauro, M. Infante, A. Bellia, 2018, SAGE open medical case reports.

"The Linosa Study": epidemiological and heritability data of the metabolic syndrome in a Caucasian genetic isolate.

G. Di Fede, G. Novelli, M. Federici, 2009, Nutrition, metabolism, and cardiovascular diseases : NMCD.

G972R IRS-1 Variant Impairs Insulin Regulation of Endothelial Nitric Oxide Synthase in Cultured Human Endothelial Cells

G. Pellegrini, G. Sesti, M. Federici, 2004, Circulation.

The Protective Effect of a Unique Mix of Polyphenols and Micronutrients against Neurodegeneration Induced by an In Vitro Model of Parkinson’s Disease

C. Ricordi, D. Lauro, V. Rovella, 2022, International journal of molecular sciences.

Hypoglycemia Assessed by Continuous Glucose Monitoring Is Associated with Preclinical Atherosclerosis in Individuals with Impaired Glucose Tolerance

G. Sesti, D. Lauro, M. A. Marini, 2011, PloS one.

Acute hyperglycemia reduces cerebrovascular reactivity: the role of glycemic variability.

P. Pasqualetti, F. Vernieri, D. Lauro, 2014, The Journal of clinical endocrinology and metabolism.

Expression study of candidate miRNAs and evaluation of their potential use as biomarkers of diabetic neuropathy.

G. Novelli, P. Borgiani, D. Lauro, 2020, Epigenomics.

Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial.

Diane M. Miller, Natalia E. Shilkina, M. C. Cantero, 2018, Lancet.

Proteomics Reveals Novel Oxidative and Glycolytic Mechanisms in Type 1 Diabetic Patients' Skin Which Are Normalized by Kidney-Pancreas Transplantation

C. Jenkinson, A. Secchi, P. Fiorina, 2010, PLoS ONE.

Benfotiamine Counteracts Glucose Toxicity Effects on Endothelial Progenitor Cell Differentiation via Akt/FoxO Signaling

A. Fukamizu, M. Federici, D. Lauro, 2006, Diabetes.

The molecular link between oxidative stress, insulin resistance, and type 2 diabetes: A target for new therapies against cardiovascular diseases.

D. Lauro, R. Lauro, D. Della-Morte, 2021, Current opinion in pharmacology.

Serum- and Glucocorticoid-Inducible Kinase 1 Delay the Onset of Endothelial Senescence by Directly Interacting with Human Telomerase Reverse Transcriptase.

M. Federici, D. Lauro, D. Della-Morte, 2016, Rejuvenation research.

Fine-scale haplotype mapping of MUT, AACS, SLC6A15 and PRKCA genes indicates association with insulin resistance of metabolic syndrome and relationship with branched chain amino acid metabolism or regulation

J. Robine, E. Khusnutdinova, C. Lautier, 2019, PloS one.

Peroxiredoxin 6, a Novel Player in the Pathogenesis of Diabetes

M. Federici, D. Lauro, M. Scioli, 2014, Diabetes.

Carotid artery intima-media thickness is associated with insulin-mediated glucose disposal in nondiabetic normotensive offspring of type 2 diabetic patients.

G. Sesti, F. Andreozzi, M. Federici, 2007, American journal of physiology. Endocrinology and metabolism.

Prdx6 Plays a Main Role in the Crosstalk between Aging and Metabolic Sarcopenia

P. Abete, D. Lauro, M. Scioli, 2020, Antioxidants.

Glucagon Like Peptide 1 and MicroRNA in Metabolic Diseases: Focusing on GLP1 Action on miRNAs

D. Lauro, D. Della-Morte, F. Pacifici, 2018, Front. Endocrinol..

Chronic obstructive pulmonary disease and diabetes

Davide Lauro, D. Lauro, P. Rogliani, 2015 .

Targeting Mechanisms Linking COPD to Type 2 Diabetes Mellitus.

M. Cazzola, D. Lauro, L. Calzetta, 2017, Trends in pharmacological sciences.

Metabolic Syndrome, Chronic Kidney, and Cardiovascular Diseases: Role of Adipokines

A. Scuteri, D. Lauro, N. Di Daniele, 2011, Cardiology research and practice.

Severe hypoglycemia in patients with known diabetes requiring emergency department care: A report from an Italian multicenter study

E. Bonora, D. Lauro, G. Zoppini, 2016, Journal of Clinical & Translational Endocrinology.

Geographic and Ethnic Inequalities in Diabetes-Related Amputations

D. Lauro, A. Andreadi, A. Bellia, 2022, Frontiers in Clinical Diabetes and Healthcare.

Endothelial function and arterial stiffness in normotensive normoglycemic first-degree relatives of diabetic patients are independent of the metabolic syndrome.

A. Scuteri, M. Federici, D. Lauro, 2008, Nutrition, metabolism, and cardiovascular diseases : NMCD.

Branched-Chain Amino Acid Database Integrated in MEDIPAD Software as a Tool for Nutritional Investigation of Mediterranean Populations

E. Khusnutdinova, C. Lautier, F. Grigorescu, 2018, Nutrients.

Exercise individualized by TRIMPi method reduces arterial stiffness in early onset type 2 diabetic patients: A randomized controlled trial with aerobic interval training.

F. Iellamo, E. Padua, D. Lauro, 2017, International journal of cardiology.

Whole-body Electromyostimulation plus Caloric Restriction in Metabolic Syndrome

C. Rosazza, D. Lauro, M. Lombardo, 2020, International Journal of Sports Medicine.

Pleiotropic effects of hypoglycemic agents: implications in asthma and COPD

D. Lauro, P. Rogliani, N. Di Daniele, 2018, Current opinion in pharmacology.

Effects of GLP-1 on Forearm Vasodilator Function and Glucose Disposal During Hyperinsulinemia in the Metabolic Syndrome

D. Lauro, V. Rovella, G. Ghirlanda, 2013, Diabetes Care.

Recent Pharmacological Options in Type 2 Diabetes and Synergic Mechanism in Cardiovascular Disease

D. Lauro, N. Di Daniele, A. Andreadi, 2023, International journal of molecular sciences.

Ghrelin Improves Endothelial Function in Patients With Metabolic Syndrome

D. Lauro, M. Tesauro, C. Cardillo, 2005, Circulation.

Platelet Isoprostane Overproduction in Diabetic Patients Treated With Aspirin

D. Lauro, S. Basili, F. Violi, 2012, Diabetes.

Polyphenol intake and cardiovascular risk factors in a population with type 2 diabetes: The TOSCA.IT study.

E. Bonora, M. Vitale, G. Riccardi, 2017, Clinical nutrition.

Decreased IRS2 and TIMP3 Expression in Monocytes From Offspring of Type 2 Diabetic Patients Is Correlated With Insulin Resistance and Increased Intima-Media Thickness

P. Gentileschi, M. Federici, M. Cardellini, 2011, Diabetes.

A common polymorphism in the promoter of UCP2 contributes to the variation in insulin secretion in glucose-tolerant subjects.

P. Marchetti, G. Sesti, M. Federici, 2003, Diabetes.

Influence of dietary fat and carbohydrates proportions on plasma lipids, glucose control and low-grade inflammation in patients with type 2 diabetes—The TOSCA.IT Study

M. Boemi, E. Bonora, M. Vitale, 2016, European Journal of Nutrition.

Retinal neurodegeneration in patients with type 1 diabetes mellitus: the role of glycemic variability

P. Pasqualetti, D. Lauro, M. Varano, 2017, Acta Diabetologica.

Association of ATF5 Gene with Metabolic Syndrome and Insulin Resistance in Mediterranean Populations

C. Lautier, F. Grigorescu, A. Tsatsoulis, 2018, Diabetes.

Insulin Resistance and Acne: The Role of Metformin as Alternative Therapy in Men

D. Lauro, N. Di Daniele, A. Andreadi, 2022, Pharmaceuticals.

Role of Serum and Glucocorticoid-Inducible Kinase (SGK)-1 in Senescence: A Novel Molecular Target Against Age-Related Diseases.

F. Guadagni, P. Abete, M. Federici, 2015, Current medicinal chemistry.

M. Federici, D. Lauro, P. Preziosi, 2014, PloS one.

The mitochondrial Italian Human Proteome Project initiative (mt-HPP).

P. Pandolfi, M. Brunori, V. De Pinto, 2013, Molecular bioSystems.

Aortic stiffness and hypotension episodes are associated with impaired cognitive function in older subjects with subjective complaints of memory loss.

A. Scuteri, D. Lauro, N. Di Daniele, 2013, International journal of cardiology.

Metabolic syndrome and risk of pulmonary involvement.

M. Cazzola, M. Federici, D. Lauro, 2010, Respiratory medicine.

Validation of the Composite Autonomic Symptom Score 31 (COMPASS 31) for the assessment of symptoms of autonomic neuropathy in people with diabetes

P. Cortelli, D. Lauro, V. Spallone, 2017, Diabetic medicine : a journal of the British Diabetic Association.

A Novel Mix of Polyphenols and Micronutrients Reduces Adipogenesis and Promotes White Adipose Tissue Browning via UCP1 Expression and AMPK Activation

C. Ricordi, D. Lauro, V. Rovella, 2023, Cells.

Diabetes and cognitive decline.

D. Lauro, M. Lombardo, D. Della-Morte, 2022, Advances in clinical chemistry.

Parathyroid hormone in surgery-induced weight loss: no glucometabolic effects but potential adaptive response to skeletal loading

P. Gentileschi, D. Lauro, M. Lombardo, 2018, Endocrine.

Enhancement of anti-leukemia activity of NK cells in vitro and in vivo by inhibition of leukemia cell-induced NK cell damage

S. Ferrone, D. Lauro, A. Venditti, 2015, Oncotarget.

Serum 25-hydroxyvitamin D levels are inversely associated with systemic inflammation in severe obese subjects

P. Gentileschi, M. Federici, D. Lauro, 2013, Internal and Emergency Medicine.

Overexpression of Tissue Inhibitor of Metalloproteinase 3 in Macrophages Reduces Atherosclerosis in Low-Density Lipoprotein Receptor Knockout Mice

S. Menini, P. Gentileschi, O. Schillaci, 2012, Arteriosclerosis, thrombosis, and vascular biology.

Atherosclerosis severity but not undiagnosed diabetes predicts new cardiovascular events of subjects in secondary cardiovascular prevention.

M. Copetti, F. Romeo, M. Federici, 2012, Atherosclerosis.

Post-traumatic stress disorder, coping strategies and type 2 diabetes: psychometric assessment after L’Aquila earthquake

A. Lenzi, D. Lauro, E. Jannini, 2015, Acta Diabetologica.

Parathyroid hormone and insulin resistance in distinct phenotypes of severe obesity: a cross-sectional analysis in middle-aged men and premenopausal women.

P. Gentileschi, M. Federici, D. Lauro, 2012, The Journal of clinical endocrinology and metabolism.

Role of KIR and CD16A genotypes in colorectal carcinoma genetic risk and clinical stage

N. Di Lorenzo, D. Lauro, O. Buonomo, 2016, Journal of Translational Medicine.

Effects of Whole Body Vibration Plus Diet on Insulin-Resistance in Middle-Aged Obese Subjects

M. Federici, D. Lauro, M. Lombardo, 2013, International Journal of Sports Medicine.

Sex-Genetic Interaction in the Risk for Cerebrovascular Disease.

F. Guadagni, P. Abete, D. Lauro, 2017, Current medicinal chemistry.

Atherogenic Dyslipidemia on Admission Is Associated With Poorer Outcome in People With and Without Diabetes Hospitalized for COVID-19

D. Lauro, P. Rogliani, A. Magrini, 2021, Diabetes Care.

The Gly972-->Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells.

D. Accili, G. Sesti, M. Federici, 1999, The Journal of clinical investigation.

Type 2 diabetes mellitus impairs the maturation of endothelial progenitor cells and increases the number of circulating endothelial cells in peripheral blood

D. Lauro, R. Saccardi, A. Coppola, 2012, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Plasma concentrations of progesterone and estradiol and the relation to reproduction in Galápagos land iguanas, Conolophus marthae and C. subcristatus (Squamata, Iguanidae).

Monica Carosi, Sergio Bernardini, Leonardo Vignoli, 2016, Animal reproduction science.

The Neuro-Ischaemic Charcot Foot: Prevalence, Characteristics and Severity of Peripheral Arterial Disease in Acute Charcot Neuro-Arthropathy

D. Lauro, N. Di Daniele, A. Bellia, 2022, Journal of clinical medicine.

High plant-based diet and physical activity in women during menopausal transition

E. Padua, M. Perrone, D. Lauro, 2021, Nutrition & Food Science.

Glucose variability: a new risk factor for cardiovascular disease

D. Lauro, F. Barillà, A. Bellia, 2023, Acta Diabetologica.

Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial.

Debra F. Weinstein, Michael G. Miller, M. A. Ferreira, 2019, Lancet.

A multidisciplinary team reduces in‐hospital clinical complications and mortality in patients with diabetic foot ulcers

D. Lauro, A. Bellia, L. Giurato, 2023, Diabetes/metabolism research and reviews.

Below-the-ankle arterial disease: a new marker of coronary artery disease in patients with diabetes and foot ulcers

D. Lauro, A. Bellia, L. Giurato, 2022, Acta Diabetologica.

Risk factors for diabetic foot ulcers: an Albanian retrospective study of inpatients with type 2 diabetes.

D. Lauro, D. Della-Morte, N. Di Daniele, 2022, European review for medical and pharmacological sciences.

Genetic approach in personalized medicine in type 2 diabetes

D. Lauro, D. Della-Morte, F. Pacifici, 2021, Health Education and Care.

Prevalence of Cardiovascular Risk Factors and Coronary Angiographic Findings in High-Risk Immigrant Communities in Italy

D. Lauro, F. Barillà, M. Ifrim, 2023, Journal of personalized medicine.

Adiponectin Isoforms in Elderly Patients with or without Coronary Artery Disease

M. Federici, D. Lauro, R. Lauro, 2010, Journal of the American Geriatrics Society.