Shaozhen Xie

发表

APPL Suppresses Androgen Receptor Transactivation via Potentiating Akt Activity*

Chawnshang Chang, Lin Yang, Hui-Kuan Lin, 2003, The Journal of Biological Chemistry.

Interleukin-6 differentially regulates androgen receptor transactivation via PI3K-Akt, STAT3, and MAPK, three distinct signal pathways in prostate cancer cells.

Chawnshang Chang, Lin Yang, Hui-Kuan Lin, 2003, Biochemical and biophysical research communications.

Subfertility with defective folliculogenesis in female mice lacking testicular orphan nuclear receptor 4.

Y. Hung, Chawnshang Chang, Shaozhen Xie, 2008, Molecular endocrinology.

STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer

E. Winer, N. Lin, D. Dillon, 2022, Nature Communications.

Combination inhibition of PI 3 K and mTORC 1 yields durable remissions in mice bearing orthotopic patient-derived xenografts of HER 2-positive breast cancer brain metastases

E. Winer, K. Ligon, E. Marco, 2016 .

Rac1-mediated membrane raft localization of PI3K/p110β is required for its activation by GPCRs or PTEN loss

T. Roberts, Jean J. Zhao, Shaozhen Xie, 2016, eLife.

Androgen suppresses PML protein expression in prostate cancer CWR22R cells.

J. Ni, Chawnshang Chang, Lin Yang, 2004, Biochemical and biophysical research communications.

The role of the PIK3CA gene in the development and aging of the brain

T. Roberts, Jean J. Zhao, Shaozhen Xie, 2021, Scientific reports.

PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer

G. Freeman, R. Bronson, T. Roberts, 2018, Cell reports.

CDK4/6 inhibition triggers anti-tumor immunity

M. Ellis, E. Winer, J. Hoog, 2017, Nature.

p16INK4A-deficiency predicts response to combined HER2 and CDK4/6 inhibition in HER2+ breast cancer brain metastases

Henry W. Long, E. Winer, N. Lin, 2022, Nature Communications.

Drug Resistance in HER2-Positive Breast Cancer Brain Metastases: Blame the Barrier or the Brain?

E. Winer, N. Lin, Jean J. Zhao, 2018, Clinical Cancer Research.

Combination inhibition of PI3K and mTORC1 yields durable remissions in orthotopic patient-derived xenografts of HER2-positive breast cancer brain metastases

E. Winer, K. Ligon, Guocheng Yuan, 2016, Nature Medicine.

Functional characterization of an isoform-selective inhibitor of PI3K-p110β as a potential anticancer agent.

N. Gray, Qingsong Liu, C. Benes, 2012, Cancer discovery.

Suppression of Androgen Receptor-mediated Transactivation and Cell Growth by the Glycogen Synthase Kinase 3β in Prostate Cells*

Chawnshang Chang, Lin Yang, Hui-Kuan Lin, 2004, Journal of Biological Chemistry.

Tyrosine receptor kinase B is a drug target in astrocytomas

W. Hahn, R. Beroukhim, K. Ligon, 2017, Neuro-oncology.

STING agonism overcomes STAT3-mediated immunosuppression and adaptive resistance to PARP inhibition in ovarian cancer

G. Freeman, U. Matulonis, Shaozhen Xie, 2022, Journal for ImmunoTherapy of Cancer.

TR4 nuclear receptor functions as a fatty acid sensor to modulate CD36 expression and foam cell formation

J. Ni, Chawnshang Chang, Shaozhen Xie, 2009, Proceedings of the National Academy of Sciences.

CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer

R. Young, Tong Ihn Lee, N. Gray, 2015, Cell.

Regulation of interleukin‐6‐mediated PI3K activation and neuroendocrine differentiation by androgen signaling in prostate cancer LNCaP cells

P. di Sant'Agnese, J. Ni, Chawnshang Chang, 2004, The Prostate.

Divergent Roles of PI3K Isoforms in PTEN-Deficient Glioblastomas

P. Wen, K. Ligon, R. Bronson, 2020, Cell reports.

Induction of Androgen Receptor Expression by Phosphatidylinositol 3-Kinase/Akt Downstream Substrate, FOXO3a, and Their Roles in Apoptosis of LNCaP Prostate Cancer Cells*

J. Ni, Chawnshang Chang, Lin Yang, 2005, Journal of Biological Chemistry.

Improving orthotopic mouse models of patient-derived breast cancer brain metastases by a modified intracarotid injection method

Jean J. Zhao, Shaozhen Xie, P. Pan, 2019, Scientific Reports.

Oxidative stress stimulates testicular orphan receptor 4 through forkhead transcription factor forkhead box O3a.

Chawnshang Chang, Zhao-dian Chen, Shaozhen Xie, 2008, Endocrinology.

The role of the PIK3CA gene in the development and aging of the brain

T. Roberts, Jean J. Zhao, Shaozhen Xie, 2021, Scientific Reports.

Disruption of TR4 Orphan Nuclear Receptor Reduces the Expression of Liver Apolipoprotein E/C-I/C-II Gene Cluster*

Chawnshang Chang, Shaozhen Xie, S. Yeh, 2003, Journal of Biological Chemistry.

Disruption of TR 4 Orphan Nuclear Receptor Reduces the Expression of Liver Apolipoprotein E / CI / CII Gene Cluster *

Chawnshang Chang, Shaozhen Xie, S. Yeh, 2003 .

Physiological Functions of TR2 and TR4 Orphan Nuclear Receptor

Chawnshang Chang, Shaozhen Xie, Yi-Fen Lee, 2010 .

Polyomavirus Small T Antigen Induces Apoptosis in Mammalian Cells through the UNC5B Pathway in a PP2A-Dependent Manner

T. Roberts, Shaida Andrabi, Shaozhen Xie, 2020, Journal of Virology.

Tocopherol-associated protein suppresses prostate cancer cell growth by inhibition of the phosphoinositide 3-kinase pathway.

E. Messing, Ming Chen, J. Ni, 2005, Cancer research.

Increased Acetylation in the DNA-binding Domain of TR4 Nuclear Receptor by the Coregulator ARA55 Leads to Suppression of TR4 Transactivation*

J. Ni, Chawnshang Chang, Shaozhen Xie, 2011, The Journal of Biological Chemistry.

PI3Kβ controls immune evasion in PTEN-deficient breast tumours

G. Freeman, S. Prakadan, A. Shalek, 2023, Nature.

Loss of testicular orphan receptor 4 impairs normal myelination in mouse forebrain.

Chawnshang Chang, Shaozhen Xie, Liang Wang, 2007, Molecular endocrinology.

Lysine vitcylation is a novel vitamin C-derived protein modification that enhances STAT1-mediated immune response

L. Cantley, Jean J. Zhao, J. Asara, 2023, bioRxiv.

In vitro and In vivo Anticancer Effects of the Novel Vitamin E Ether Analogue RRR-α-Tocopheryloxybutyl Sulfonic Acid in Prostate Cancer

J. Ni, S. Yeh, Shaozhen Xie, 2009, Clinical Cancer Research.

STING agonism overcomes STAT3-mediated immunosuppression and adaptive resistance to PARP inhibition in ovarian cancer

U. Matulonis, Shaozhen Xie, P. Konstantinopoulos, 2023, Journal for ImmunoTherapy of Cancer.