I. Nakashima

发表

Protein phosphatase 2A-linked and -unlinked caspase-dependent pathways for downregulation of Akt kinase triggered by 4-hydroxynonenal

W. Liu, A. Akhand, K. Takeda, 2003, Cell Death and Differentiation.

Mercuric chloride stimulates distinct signal transduction pathway for DNA synthesis in a T‐cell line, CTLL‐2

A. Akhand, I. Nakashima, Jun-qing Du, 2000, Journal of cellular biochemistry.

Surgical stress reduces mortality from endotoxin shock

M. Nagino, Y. Nimura, I. Nakashima, 2001, Langenbeck’s Archives of Surgery.

Superoxide-mediated early oxidation and activation of ASK1 are important for initiating methylglyoxal-induced apoptosis process.

T. Miyata, A. Akhand, H. Suzuki, 2001, Free radical biology & medicine.

Virulence for mice of Klebsiella strains belonging to the O1 group: relationship to their capsular (K) types

I. Nakashima, M. Mori, M. Ohta, 1983, Infection and immunity.

cDNA cloning of mouse ret proto-oncogene and its sequence similarity to the cadherin superfamily.

N. Asai, I. Nakashima, T. Iwamoto, 1993, Oncogene.

Redox-linked signal transduction pathways for protein tyrosine kinase activation.

A. Akhand, Y. Kawamoto, I. Nakashima, 2002, Antioxidants & redox signaling.

Normal regulatory alpha/beta T cells effectively eliminate abnormally activated T cells lacking the interleukin 2 receptor beta in vivo.

Yan Zhou, T. Mak, I. Nakashima, 1999 .

Mercuric chloride mediates a protein sulfhydryl modification‐based pathway of signal transduction for activating Src kinase which is independent of the phosphorylation / dephosphorylation of a carboxyl terminal tyrosine

A. Akhand, M. Kato, H. Suzuki, 1996, Journal of cellular biochemistry.

Can cysteine direct tyrosine in signal transduction for environment-oriented gene control?

I. Nakashima, 1996, Nagoya journal of medical science.

Osmotic stress-mediated activation of RET kinases involves intracellular disulfide-bonded dimer formation.

M. Kato, H. Suzuki, I. Nakashima, 2001, Antioxidants & redox signaling.

Effect of dimethyl sulfoxide on natural resistance to bacterial infections in mice.

I. Nakashima, T. Kobayashi, N. Kato, 1973, Japanese journal of microbiology.

Essential Roles of CD8+CD122+ Regulatory T Cells in the Maintenance of T Cell Homeostasis

Y. Kawamoto, I. Nakashima, Haruhiko Suzuki, 2004, The Journal of experimental medicine.

Methylglyoxal induces apoptosis in Jurkat leukemia T cells by activating c‐Jun N‐Terminal kinase

T. Miyata, A. Akhand, H. Suzuki, 2000, Journal of cellular biochemistry.

Expression of MDR1 and glutatione S transferase‐π genes and chemosensitivities in human gastrointestinal cancer

K. Isobe, I. Nakashima, H. Takagi, 1992, Cancer.

ISOLATION OF THE REGULATORY REGIONS AND GENOMIC ORGANIZATION OF THE PORCINE &agr;1,3-GALACTOSYLTRANSFERASE GENE1

T. Starzl, J. Fung, I. Nakashima, 2000, Transplantation.

Accelerated proliferation and interleukin-2 production of thymocytes by stimulation of soluble anti-CD3 monoclonal antibody in transgenic mice carrying a rabbit protein kinase C alpha.

D. Kioussis, M. Hagiwara, H. Hidaka, 1992, The Journal of biological chemistry.

Cepharanthine activates caspases and induces apoptosis in Jurkat and K562 human leukemia cell lines

A. Akhand, M. Kato, H. Suzuki, 2001, Journal of cellular biochemistry.

Spontaneous Vitiligo in an Animal Model for Human Melanoma

L. Rénia, L. Fiette, I. Nakashima, 2004, Cancer Research.

Melanoma : Role of Tumor-specific CD 8 + T Cells Spontaneous Vitiligo in an Animal Model for Human

L. Rénia, L. Fiette, I. Nakashima, 2004 .

RET tyrosine kinase enhances hair growth in association with promotion of melanogenesis

T. Tsuzuki, Masahide Takahashi, Y. Kawamoto, 2001, Oncogene.

Menadione biphasically controls JNK-linked cell death in leukemia Jurkat T cells.

Jun Du, I. Nakashima, F. Nagase, 2002, Antioxidants & redox signaling.

Redox control of catalytic activities of membrane-associated protein tyrosine kinases.

Y. Okuno, Y. Kawamoto, I. Nakashima, 2005, Archives of biochemistry and biophysics.

Protein phosphatase 1, but not protein phosphatase 2A, dephosphorylates DNA‐damaging stress‐induced phospho‐serine 15 of p53

K. Isobe, I. Nakashima, M. Haneda, 2004, FEBS letters.

The Klebsiella O3 Lipopolysaccharide Isolated from Culture Fluid

I. Nakashima, M. Ohta, N. Kato, 1983, Microbiology and immunology.

Redox‐linked ligand‐independent cell surface triggering for extensive protein tyrosine phosphorylation

K. Isobe, I. Nakashima, T. Iwamoto, 1993, FEBS letters.

Galectin‐1 supports survival of naive T cells without promoting cell proliferation

I. Nakashima, Haruhiko Suzuki, A. Endharti, 2005, European journal of immunology.

Point mutations of the c-Ki-ras gene in carcinoma and atypical epithelium associated with congenital biliary dilation.

Y. Nimura, I. Nakashima, T. Iwamoto, 1996, The American journal of gastroenterology.

Structure of the polysaccharide moiety of the Klebsiella O3 lipopolysaccharide isolated from culture supernatant of decapsulated mutant (Klebsiella O3:K1-).

I. Nakashima, K. Morikawa, M. Ohta, 1985, Chemical & pharmaceutical bulletin.

Repair by Src kinase of function-impaired RET with multiple endocrine neoplasia type 2A mutation with substitutions of tyrosines in the COOH-terminal kinase domain for phenylalanine.

G. Sobue, Masahide Takahashi, A. Akhand, 2002, Cancer research.

Evidence of both extra- and intracellular cysteine targets of protein modification for activation of RET kinase.

Masahide Takahashi, A. Akhand, I. Nakashima, 2002, Biochemical and biophysical research communications.

Molecular mechanism of activation and superactivation of Ret tyrosine kinases by ultraviolet light irradiation.

W. Liu, A. Akhand, Y. Kawamoto, 2000, Antioxidants & redox signaling.

Ultraviolet light induces redox reaction-mediated dimerization and superactivation of oncogenic Ret tyrosine kinases.

N. Asai, W. Liu, A. Akhand, 2000, Molecular biology of the cell.

Cell type and maturation stage-dependent polymorphism of N-linked oligosaccharides on murine lymphocytes and lymphoma cells.

T. Yoshida, I. Nakashima, N. Takahashi, 1991, Molecular immunology.

IgA1 molecules produced by tonsillar lymphocytes are under-O-glycosylated in IgA nephropathy.

Y. Hiki, I. Nakashima, Masashi Kato, 2003, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Purified protein derivative (PPD) tuberculin as a biological response modifier: I. Suppression of tumor markers by intravenous administration of PPD.

I. Nakashima, K. Kato, S. Yoshii, 1988, Nagoya journal of medical science.

Carbonyl compounds cross‐link cellular proteins and activate protein‐tyrosine kinase p60c‐Src

Wei Liu, T. Miyata, A. Akhand, 1999, Journal of cellular biochemistry.

4-hydroxynonenal induces a cellular redox status-related activation of the caspase cascade for apoptotic cell death.

T. Miyata, W. Liu, A. Akhand, 2000, Journal of cell science.

Expression of carcinoembryonic antigen (CEA) and nonspecific crossreacting antigen (NCA) in gastrointestinal cancer; the correlation with degree of differentiation.

Y. Kodera, K. Isobe, I. Nakashima, 1993, British Journal of Cancer.

Kinase Raft-Linked Signaling for Activation of c-Jun Lymphocytes Through Membrane Arsenite Induces Apoptosis of Murine T

Wei Liu, A. Akhand, M. Kato, 2000 .

4-hydroxynonenal triggers an epidermal growth factor receptor-linked signal pathway for growth inhibition.

T. Miyata, W. Liu, A. Akhand, 1999, Journal of cell science.

Level of HgCl2‐mediated phosphorylation of intracellular proteins determines death of thymic T‐lymphocytes with or without DNA fragmentation

T. Miyata, A. Akhand, M. Kato, 1998, Journal of cellular biochemistry.

Magnitude of protein tyrosine phosphorylation‐linked signals determines growth versus death of thymic T lymphocytes

A. Akhand, M. Kato, H. Suzuki, 1997, European journal of immunology.

Multiphasic modulation of signal transduction into T lymphocytes by monoiodoacetic acid as a sulfhydryl reagent

K. Isobe, A. Akhand, I. Nakashima, 1995, Journal of cellular biochemistry.

Pathway of signal delivery to murine thymocytes triggered by co-crosslinking CD3 and Thy-1 for cellular DNA fragmentation and growth inhibition.

T. Yoshida, M. Kato, I. Nakashima, 1993, Journal of immunology.

4-hydroxynonenal triggers multistep signal transduction cascades for suppression of cellular functions.

Wei Liu, A. Akhand, Y. Kawamoto, 2003, Molecular aspects of medicine.

Normal Regulatory α/β T Cells Effectively Eliminate Abnormally Activated T Cells Lacking the Interleukin 2 Receptor β in Vivo

Yan Zhou, T. Mak, I. Nakashima, 1999, The Journal of experimental medicine.

Normal Regulatory (cid:97) / (cid:98) T Cells Effectively Eliminate Abnormally Activated T Cells Lacking the Interleukin 2 Receptor (cid:98) In Vivo

T. Mak, I. Nakashima, Haruhiko Suzuki, 1999 .

Transgenic mouse model for skin malignant melanoma

Wei Liu, Masahide Takahashi, A. Akhand, 1998, Oncogene.

Elevated soluble tumor necrosis factor receptor levels in seasonal allergic rhinitis patients

M. Kato, I. Nakashima, Y. Kato, 1999, Allergy.

Evidence of Potential Regulation by Interleukin-4 of the Soluble Intercellular Adhesion Molecule 1 Level in Patients with Seasonal Allergic Rhinitis under Provocation by a Small Amount of Natural Allergen

Wei Liu, I. Nakashima, Masashi Kato, 1998, The Annals of otology, rhinology, and laryngology.

Distinct involvement of NF‐κB and p38 mitogen‐activated protein kinase pathways in serum deprivation‐mediated stimulation of inducible nitric oxide synthase and its inhibition by 4‐hydroxynonenal

Wei Liu, M. Itoigawa, N. Ishikawa, 2001, Journal of cellular biochemistry.

Aberrant melanogenesis and melanocytic tumour development in transgenic mice that carry a metallothionein/ret fusion gene.

K. Isobe, I. Nakashima, T. Iwamoto, 1991, The EMBO journal.

Protein kinase C-dependent anti-apoptotic mechanism that is associated with high sensitivity to anti-Fas antibody in ovarian cancer cell lines.

I. Nakashima, T. Okamoto, A. Hayakawa, 1999, Cancer letters.

Higher expression of topoisomerase II in lung cancers than normal lung tissues: different expression pattern from topoisomerase I.

K. Shimokata, I. Nakashima, K. Isobe, 1993, Biochemical and biophysical research communications.

Expression of glutathione-S-transferases alpha and pi in gastric cancer: a correlation with cisplatin resistance.

Y. Kodera, K. Isobe, I. Nakashima, 1994, Cancer chemotherapy and pharmacology.

The herbal medicine Sho-saiko-to inhibits growth and metastasis of malignant melanoma primarily developed in ret-transgenic mice.

N. Asai, W. Liu, M. Kato, 1998, The Journal of investigative dermatology.

Cell type-oriented differential modulatory actions of saikosaponin-d on growth responses and DNA fragmentation of lymphocytes triggered by receptor-mediated and receptor-bypassed pathways.

K. Isobe, M. Kato, I. Nakashima, 1995, Immunopharmacology.

Neuroblastoma in a transgenic mouse carrying a metallothionein/ret fusion gene.

I. Nakashima, T. Iwamoto, W. Wajjwalku, 1993, British Journal of Cancer.

Establishment of a human DAF/HRF20 double transgenic mouse line is not sufficient to suppress hyperacute rejection

K. Isobe, I. Nakashima, H. Okada, 1996, Surgery Today.

Functional differences among multiple isoforms of guinea pig decay-accelerating factor.

C. He, G. Wang, I. Nakashima, 1998, Journal of immunology.

of Guinea Pig Decay-Accelerating Factor Functional Differences Among Multiple Isoforms

I. Nakashima, H. Okada, N. Okada, 1998 .

SUMMARY 4-hydroxynonenal induces a cellular redox status-related activation of the caspase cascade for apoptotic cell death

Wei Liu, T. Miyata, N. Ishikawa, 2000 .

In vivo effects of bacterial lipopolysaccharide on proliferation of macrophage colony-forming cells in bone marrow and peripheral lymphoid tissues

T. Yokochi, I. Nakashima, K. Yoshida, 1985, Infection and immunity.

Abundant production of nitric oxide from murine macrophages by direct stimulation of tumor cells.

I. Nakashima, K. Isobe, 1993, Biochemical and biophysical research communications.

Nitric oxide as an inflammatory mediator of radiation pneumonitis in rats.

Y. Hasegawa, K. Shimokata, K. Isobe, 1997, The American journal of physiology.

Adjuvant actions of polyclonal lymphocyte activators. IV. Augmentation of antigen retention occurring early and transiently at the site of injection and in the draining lymph node.

T. Yokochi, I. Nakashima, F. Nagase, 1981, Cellular immunology.

Adjuvant actions of polyclonal lymphocyte activators. I. Comparison and characterization of their actions in antibody response to deaggregated bovine serum albumin.

T. Yokochi, I. Nakashima, F. Nagase, 1980, Cellular immunology.

Regulation of mouse GADD34 gene transcription after DNA damaging agent methylmethane sulfonate.

K. Isobe, I. Nakashima, Hengyi Xiao, 2004, Gene.

Inhibition of Fas‐mediated apoptotic cell death of murine T lymphocytes in a mouse model of immunosenescence in linkage to deterioration in cell membrane raft function

Jun Du, Y. Kawamoto, I. Nakashima, 2004, Immunology.

Amount of pollen has an effect on the systemic and local levels of soluble ICAM‐1 in patients with seasonal allergic rhinitis

M. Kato, I. Nakashima, N. Yanagita, 1996, Allergy.

Soluble ICAM‐1 as a regulator of nasal allergic reaction under natural allergen provocation

M. Kato, I. Nakashima, N. Yanagita, 1995, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Oncogenicity of the ret transforming gene in MMTV/ret transgenic mice.

K. Isobe, T. Yoshida, I. Nakashima, 1990, Oncogene.

Evidence of a novel redox-linked activation mechanism for the Src kinase which is independent of tyrosine 527-mediated regulation.

A. Akhand, M. Kato, H. Suzuki, 1996, Oncogene.

Redox mechanism as alternative to ligand binding for receptor activation delivering disregulated cellular signals.

K. Isobe, I. Nakashima, L. Ma, 1994, Journal of immunology.

Control of Genetically Prescribed Protein Tyrosine Kinase Activities by Environment-Linked Redox Reactions

Y. Kawamoto, I. Nakashima, Masashi Kato, 2011, Enzyme research.

Direct gene replacement of the mouse α(1,3)‐galactosyltransferase gene with human α(1,2)‐fucosyltransferase gene: Converting α‐galactosyl epitopes into H antigens

R. Kannagi, I. Nakashima, T. Muramatsu, 1997 .

Induction of Apoptosis and Tyrosine Phosphorylation of Cellular Proteins in T Cells and Non‐T Cells by Stimulation with Concanavalin A

Jun Du, I. Nakashima, F. Nagase, 1998, Microbiology and immunology.

Different serum soluble Fas levels in patients with allergic rhinitis and bronchial asthma

T. Yoshimoto, M. Kato, I. Nakashima, 1999, Allergy.

Delivery of an accessory signal for cell activation by exogenous phosphatidylinositol‐specific phospholipase C

R. Taguchi, T. Yoshida, I. Nakashima, 1992, FEBS letters.

Production of the constant domain of murine T‐cell receptor β‐chain in Escherichia coli

Y. Kurosawa, I. Nakashima, F. Nagase, 1987, FEBS letters.

Evidence of synergy between Thy-1 and CD3/TCR complex in signal delivery to murine thymocytes for cell death.

R. Taguchi, T. Yoshida, I. Nakashima, 1991, Journal of immunology.

Late breaking abstracts

T. Sejnowski, C. Phillips, P. Maquet, 2007, Neuromuscular Disorders.

Involvement of MKK6 in TCRαβintCD69lo: a target population for apoptotic cell death in thymocytes

T. Ohhata, M. Hagiwara, H. Kimura, 2003 .

Normal thymic selection, superantigen-induced deletion and Fas-mediated apoptosis of T cells in IL-2 receptor beta chain-deficient mice.

T. Mak, I. Nakashima, D. Bouchard, 1997, International immunology.

Immunosuppressive activity induced by nitric oxide in culture supernatant of activated rat alveolar macrophages.

T. Kawabe, K. Shimokata, I. Nakashima, 1992, Immunology.

Identification and Characterization of a Unique Tumor-associated Surface Antigen on LI 210 Leukemia Cells Recognized by Semisyngeneic Antisera1

T. Yokochi, K. Isobe, I. Nakashima, 2006 .

Identification and Characterization of a Unique Tumor-associated Surface Antigen on LI 210 Leukemia Cells Recognized by Semisyngeneic Antisera 1

T. Yokochi, K. Isobe, I. Nakashima, 2006 .

Identification and characterization of a unique tumor-associated surface antigen on L1210 leukemia cells recognized by semisyngeneic antisera.

T. Yokochi, K. Yamada, I. Nakashima, 1987, Cancer research.

TCR‐Independent Induction of Low Responsiveness by Chemically Fixed Cells in Alloreactive CTL Clones and Its Prevention through Cognate Cell‐Cell Interaction

I. Nakashima, F. Nagase, T. Lwin, 1995, Microbiology and immunology.

Modes of activation of mitogen-activated protein kinases and their roles in cepharanthine-induced apoptosis in human leukemia cells.

A. Akhand, I. Nakashima, Haruhiko Suzuki, 2002, Cellular signalling.

Induction of high-grade anti-tumor immunity by use of a recombinant H-2Kb/avian erythroblastosis virus erbB gene transfectant

Tomoaki Yoshida, K. Isobe, I. Nakashima, 1990, Cancer Immunology, Immunotherapy.

Molecular Basis of Evolutionary Loss of the α1,3-Galactosyltransferase Gene in Higher Primates*

T. Starzl, R. Kannagi, J. Fung, 2002, The Journal of Biological Chemistry.

Glycyrrhizin as a promoter of the late signal transduction for interleukin-2 production by splenic lymphocytes.

T. Yokochi, M. Kato, I. Nakashima, 1993, Immunology.

Reactive carbonyl compounds as uremic toxins.

T. Miyata, I. Nakashima, K. Kurokawa, 2001, Contributions to nephrology.

Phorbol 12-myristate 13-acetate protects Jurkat cells from methylglyoxal-induced apoptosis by preventing c-Jun N-terminal kinase-mediated leakage of cytochrome c in an extracellular signal-regulated kinase-dependent manner.

Jun Du, I. Nakashima, F. Nagase, 2004, Molecular pharmacology.

Redox control of T-cell death.

A. Akhand, I. Nakashima, Haruhiko Suzuki, 2002, Antioxidants & redox signaling.

Evidence of redox‐linked signaling for producing a giant signal complex

K. Isobe, A. Akhand, I. Nakashima, 1995, Journal of cellular biochemistry.

The Control of Human Immunosystem by Using Paeony Root Drug

I. Nakashima, Haruhiko Suzuki, M. Rifa’i, 2010 .

Paeoniflorin induces apoptosis of lymphocytes through a redox‐linked mechanism

Jun Du, A. Akhand, I. Nakashima, 2004, Journal of cellular biochemistry.

Glyoxal and methylglyoxal induce lyoxal and methyglyoxal induce aggregation and inactivation of ERK in human endothelial cells.

T. Miyata, A. Akhand, M. Kato, 2001, Free radical biology & medicine.

Activation of caspase-8 is critical for sensitivity to cytotoxic anti-Fas antibody-induced apoptosis in human ovarian cancer cells

Y. Kawamoto, H. Suzuki, I. Nakashima, 2002, Apoptosis.

Mercuric chloride induces increases in both cytoplasmic and nuclear free calcium ions through a protein phosphorylation-linked mechanism.

A. Akhand, M. Kato, H. Suzuki, 1999, Free radical biology & medicine.

Murine lymph node‐derived stromal cells effectively support survival but induce no activation/proliferation of peripheral resting T cells in vitro

I. Nakashima, Haruhiko Suzuki, Jianghong Wu, 2003, Immunology.

Bidirectional control by glycyrrhizin of the growth response of lymphocytes stimulated through a receptor-bypassed pathway.

I. Nakashima, T. Iwamoto, K. Isobe, 1992, Immunology letters.

Mice Lacking Interleukin-2 (IL-2)/IL-15 Receptor β Chain Are Susceptible to Infection with Avirulent Salmonella enterica subsp. enterica Serovar Choleraesuis but Mice Lacking IL-2 Are Resistant

I. Nakashima, Y. Yoshikai, Haruhiko Suzuki, 2001, Infection and Immunity.

Aberrancy in immunogenicity and cell-surface expression of H-2 antigens on erythrocytes

Y. Hasegawa, Tomoaki Yoshida, T. Yokochi, 1986, Immunogenetics.

Ontogeny of the erythrocyte-dependent IgM antibody responses to cell membrane antigens.

I. Nakashima, F. Nagase, N. Kato, 1984, Developmental and comparative immunology.

Amniotic Fluid Enhances Allogeneic Cytotoxic T Cell Responses, Whereas It Suppresses Mitogen‐Stimulated Lymphocyte Proliferation

K. Isobe, I. Nakashima, S. Goto, 1994, Microbiology and immunology.

A nitric oxide‐releasing reagent, S‐nitroso‐N‐acetylpenicillamine, enhances the expression of superoxide dismutases mRNA in the murine macrophage cell line RAW264‐7

H. Saito, I. Nakashima, H. Sano, 1997, Immunology.

Novel hairless RET-transgenic mouse line with melanocytic nevi and anagen hair follicles.

T. Tsuzuki, Masahide Takahashi, K. Isobe, 2006, The Journal of investigative dermatology.

Serum-soluble Fas levels as a marker to distinguish allergic and nonallergic rhinitis.

M. Kato, I. Nakashima, M. Kageyama, 1999, The Journal of allergy and clinical immunology.

Interferon and Cytotoxic Factor (Cytotoxin) Released in the Blood of Mice Infected with Mycobacterium bovis BĆG

I. Nakashima, M. Ohta, N. Kato, 1979, Microbiology and immunology.

Interferon production in mice by the capsular polysaccharide of Klebsiella pneumoniae

I. Nakashima, N. Kato, M. Ota, 1975, Infection and immunity.

Further Evaluation of the Pregnancy‐Linked Down‐Regulation of the Paternal Antigen‐Specific Splenic Cytotoxic T Lymphocyte Activity in Allogeneically Pregnant Mice

K. Isobe, I. Nakashima, S. Goto, 1992, Microbiology and immunology.

Microbial Adjuvant and Autoimmunity

I. Nakashima, A. Noda, J. Asai, 1980, Microbiology and immunology.

A possible site of in vivo action of cyclosporin A for transplantation immunity: comparative study with cyclophosphamide.

K. Shimokata, I. Nakashima, F. Nagase, 1991, Immunobiology.

Cytokine‐Independent Proliferation of IL‐2‐Nonproducing CTL Clones in Association with High TCR‐Signal Transduction Responses

I. Nakashima, F. Nagase, T. Lwin, 1996, Microbiology and immunology.

Down‐Regulation of T‐Cell Proliferation in Response to Soluble Anti‐CD3 Antibodies through Development of Redirected Cytolytic Activity Eliminating Costimulatory Cells

I. Nakashima, F. Nagase, T. Lwin, 1995, Microbiology and immunology.

Biphasic radiation-sensitivity of the transplantation immunity for rejection of an allogeneic ascites tumor.

K. Shimokata, T. Yoshida, I. Nakashima, 1988, Immunobiology.

A novel subset of antigenic cells triggers B-cell responses to MHC antigens

I. Nakashima, P. Lake, 1979, Nature.

Promotion of proliferation of murine hematopoietic stem cells by growth factors in murine amniotic fluid.

I. Nakashima, Z. Heidari, K. Kiuchi, 1996, Journal of reproductive immunology.

Inhibitory effect of bestatin on the growth of human lymphocytes.

I. Nakashima, S. Goto, Y. Tomoda, 1992, Immunopharmacology.

Establishment of Drug Resistance in Human Gastric and Colon Carcinoma Xenograft Lines

K. Isobe, I. Nakashima, S. Akiyama, 1991, Japanese journal of cancer research : Gann.

Establishment of a murine leukemia L1210‐specific T‐cell clone displaying novel in vivo anti‐tumor activity

Tomoaki Yoshida, T. Yokochi, K. Isobe, 1986, International journal of cancer.

Glyoxal and methylglyoxal trigger distinct signals for map family kinases and caspase activation in human endothelial cells.

T. Miyata, R. Inagi, A. Akhand, 2001, Free radical biology & medicine.

Enhancement of nitric oxide production from activated macrophages by glycyrrhizin.

K. Isobe, I. Nakashima, K. Isobe, 1996, The American journal of Chinese medicine.

Modulation by glycyrrhizin of the cell-surface expression of H-2 class I antigens on murine tumour cell lines and normal cell populations.

T. Yoshida, I. Nakashima, F. Nagase, 1990, Immunology.

Adjuvant action of bacterial lipopolysaccharide in induction of delayed-type hypersensitivity to protein antigens.

I. Nakashima, M. Ohta, N. Kato, 1982, Cellular immunology.

Effect of Capsular Polysaccharide of Klebsiella pneumoniae on Host Resistance to Bacterial Infections

I. Nakashima, N. Kato, S. Naito, 1979, Microbiology and immunology.

Effect of capsular polysaccharide of Klebsiella pneumoniae on Host resistance to bacterial infections. II. Effects on peritoneal leukocytes of normal mice and mice infected with virulent Salmonella enteritidis.

I. Nakashima, N. Kato, O. Kato, 1976, Japanese journal of microbiology.

Effect of Capsular Polysaccharide of Klebsiella pneumoniae on Host Resistance to Bacterial Infections

I. Nakashima, Jun-ya Asai, N. Kato, 1979, Microbiology and immunology.

Adjuvant action of capsular polysaccharide of Klebsiella pneumoniae on antibody response. VI. Site of its action.

I. Nakashima, F. Nagase, N. Kato, 1977, Zeitschrift fur Immunitatsforschung. Immunobiology.

Effect of Capsular Polysaccharide of Klebsiella pneumoniae on the Differentiation and Functional Capacity of Macrophages Cultured In Vitro

T. Yokochi, I. Nakashima, N. Kato, 1977, Microbiology and immunology.

Effect of capsular polysaccharide of Klebsiella pneumoniae on host resistance to bacterial infections. I. Induction of increased susceptibility to infections in mice.

I. Nakashima, N. Kato, O. Kato, 1976, Japanese journal of microbiology.

Adjuvant action of capsular polysaccharide of Klebsiella pneumoniae on antibody response. V. Further biological properties of the active substance.

I. Nakashima, M. Ohta, N. Kato, 1976, Japanese journal of microbiology.

Cellular aspects of non-specific stimulation of antibody production by capsular polysaccharide of Klebsiella pneumoniae.

I. Nakashima, N. Kato, T. Kojima, 1976, Immunology.

Non-specific stimulation of immunoglobulin synthesis in mice by capsular polysaccharide of Klebsiella pneumoniae.

I. Nakashima, N. Kato, 1974, Immunology.

Adjuvant action of capsular polysaccharide of Klebsiella pneumoniae on antibody response. II. Factors affecting its action.

I. Nakashima, T. Kobayashi, N. Kato, 1973, Japanese journal of microbiology.

Adjuvant action of capsular polysaccharide of Klebsiella pneumoniae on antibody response. I. Intensity of its action.

I. Nakashima, 1972, Journal of immunology.

Alterations in the antibody response to bovine serum albumin by capsular polysaccharide of Klebsiella pneumoniae.

I. Nakashima, T. Kobayashi, N. Kato, 1971, Journal of immunology.

Adjuvant Action of Capsular Polysaccharide of Klebsiella pneumoniae on Antibody Response

T. Yokochi, I. Nakashima, N. Kato, 1972, Microbiology and immunology.

Effect of Capsular Polysaccharide of Klebsiella pneumoniae on Host Resistance to Bacterial Infections

I. Nakashima, Jun-ya Asai, N. Kato, 1979, Microbiology and immunology.

Allotype-linked immune response genes: roles in network control of the immune system.

T. Yoshida, I. Nakashima, T. Iwamoto, 1991, Experimental and clinical immunogenetics.

Characterization of antibody responses of local lymph nodes to antigen given under the oral submucosa.

T. Yoshida, I. Nakashima, J. Asai, 1992, Immunobiology.

Further Studies of the Polysaccharide of Klebsiella pneumoniae Possessing Strong Adjuvanticity: III. Augmentation of the Antibody Response to Subcutaneously Injected Sheep Red Blood Cells by the Adjuvant Polysaccharide

T. Yokochi, K. Isobe, I. Nakashima, 1982, Microbiology and immunology.

Differential effector functions of central and peripheral compartments of immune response system: characterization of immune responses in the spleen and mesenteric lymph nodes to directly injected sheep red blood cells.

I. Nakashima, N. Kato, T. Kondo, 1982, Immunobiology.

Suppression of B-memory cell function by polyclonal lymphocyte activators.

T. Yokochi, I. Nakashima, N. Kato, 1981, Immunobiology.

Formation of Mononuclear Phagocyte (Macrophage) Colonies by Mouse Spleen Cells in Liquid Culture

T. Yokochi, I. Nakashima, M. Ohta, 1981, Microbiology and immunology.

Adjuvant Action of Capsular Polysaccharide of Klebsiella pneumoniae on Antibody Response

T. Yokochi, I. Nakashima, S. Iijima, 1980, Microbiology and immunology.

Different Effects of the Capsular Polysaccharide of Klebsiella pneumoniae on the Functions of Various Subpopulations of B Cells in the Immune Response of Mice to T‐Dependent Antigen

T. Yokochi, I. Nakashima, F. Nagase, 1979, Microbiology and immunology.

Further Studies on Amplification of Cell‐Associated Immunological Memory by Secondary Antigenic Stimulus

I. Nakashima, N. Kato, 1978, Microbiology and immunology.

Adjuvant action of capsular polysaccharide of Klebsiella pneumoniae on antibody response. VII. Further purification of the active substance.

I. Nakashima, M. Mori, M. Ohta, 1973, Microbiology and immunology.

Comparative studies on the actions of antigen and polyclonal B-cell activator in differentiation and proliferation of B-cells and B memory cells.

T. Yokochi, I. Nakashima, F. Nagase, 1976, Immunology.

Maintenance and amplification of cell-associated immunological memory in in vivo culture system.

I. Nakashima, N. Kato, 1975, Cellular immunology.

Amplification of cell-associated immunological memory by secondary antigenic stimulus. Secondary type increase in memory.

I. Nakashima, N. Kato, 1975, Immunology.

Adjuvant action of capsular polysaccharide of Klebsiella pneumoniae on antibody response. IV. The roles of antigen and adjuvant for induction of primary and secondary antibody responses and for development of immunological memory to bovine serum albumin.

I. Nakashima, N. Kato, 1975, Japanese journal of microbiology.

The effect of antigen doses and time intervals between antigen injections on secondary, tertiary and quaternary antibody responses. Establishment of hyperimmunization with bovine serum albumin in mice treated with capsular polysaccharide of Klebsiella pneumoniae.

I. Nakashima, T. Kobayashi, N. Kato, 1974, Immunology.

Adjuvant actions of polyclonal lymphocyte activators. V. Proliferation of macrophage colony-forming cells in the draining lymph node.

T. Yokochi, I. Nakashima, K. Yoshida, 1985, Cellular immunology.

Interferon and Cytotoxic Factor (Cytotoxin) Released in the Blood of Mice Infected with Mycobacterium bovis BCG

I. Nakashima, M. Ohta, N. Kato, 1979, Microbiology and immunology.

Adjuvant actions of polyclonal lymphocyte activators. III. Two distinct types of T-initiating adjuvant action demonstrated under different experimental conditions.

T. Yokochi, I. Nakashima, F. Nagase, 1980, Cellular immunology.

Augmented production of granulocyte-macrophage colony-stimulating factor and alpha/beta interferon in mice inoculated with heat-killed Corynebacterium liquefaciens

M. Ichihara, K. Shimokata, T. Yoshida, 1991, Infection and immunity.

Mononuclear Phagocyte Colony Formation of Human Spleen Cells in Liquid Culture

T. Kondo, I. Nakashima, N. Kato, 1985, Microbiology and immunology.

Formation of Mononuclear Phagocyte (Macrophage) Colonies by Mouse Spleen Cells in Liquid Culture

T. Yokochi, I. Nakashima, F. Nagase, 1980, Microbiology and immunology.

Further Studies on Generation of Macrophages in In Vitro Cultures of Mouse Spleen Cells and Its Inhibition by the Capsular Polysaccharide of Klebsiella pneumoniae

T. Yokochi, I. Nakashima, N. Kato, 1979, Microbiology and immunology.

Microbial adjuvant and autoimmunity. I. Induction of antibody responses to syngeneic tissue extracts in mice treated with capsular polysaccharide of Klebsiella pneumoniae.

I. Nakashima, N. Kato, 1975, Japanese journal of microbiology.

Depression of afferent arc of the in vivo cytotoxic T-cell immunity by bacterial lipopolysaccharides.

K. Shimokata, T. Yoshida, I. Nakashima, 1985, Cellular immunology.

Alterations in the Immunogenic Properties of Sheep Erythrocytes by Sonic Disruption

I. Nakashima, F. Nagase, N. Kato, 1982, Microbiology and immunology.

Adjuvant actions of polyclonal lymphocyte activators. II. Comparison and characterization of their actions in initiation and potentiation of immune responses to T-dependent and T-independent soluble antigens.

I. Nakashima, F. Nagase, N. Kato, 1980, Cellular immunology.

The Klebsiella 03 Lipopolysaccharide Isolated from Culture Fluid: Structure of the Polysaccharide Moiety

I. Nakashima, M. Ohta, N. Kato, 2013 .

Promotion of cytotoxic T-cell generation in mixed leukocyte culture by phosphatidylinositol-specific phospholipase C from Bacillus thuringiensis

R. Taguchi, M. Kato, I. Nakashima, 1995, Infection and immunity.

Augmentation of antibody responses of mice to inhaled protein antigens by simultaneously inhaled bacterial lipopolysaccharides.

K. Shimokata, I. Nakashima, F. Nagase, 1986, Immunobiology.

Adjuvant Action of Capsular Polysaccharide of Klebsiella pneumoniae on Antibody Response

I. Nakashima, M. Mori, M. Ohta, 1979, Japanese journal of microbiology.

Correlation between strong adjuvanticity of Klebsiella O3 lipopolysaccharide and its ability to induce interleukin-1 secretion.

I. Nakashima, N. Kato, N. Kido, 1984, Cellular immunology.

Microbial Adjuvant and Autoimmunity

T. Yokochi, I. Nakashima, Jun-ya Asai, 1986, Microbiology and immunology.

Adjuvant Activity of Klebsiella O3 Lipopolysaccharide: No Contribution of Proteins to the Expression of Adjuvant Activity

I. Nakashima, M. Mori, N. Agata, 1983, Microbiology and immunology.

Experimental autoimmune hepatitis in mice after immunization with syngeneic liver proteins together with the polysaccharide of Klebsiella pneumoniae.

T. Yokochi, I. Nakashima, S. Kakumu, 1983, Gastroenterology.

Adjuvant action of bacterial lipopolysaccharide in induction of delayed-type hypersensitivity to protein antigens. II. Relationships of intensity of the action to that of other immunological activities.

I. Nakashima, M. Ohta, N. Kato, 1982, Immunobiology.

Further Studies of the Polysaccharide of Klebsiella pneumoniae Possessing Strong Adjuvanticity: II. Serological Relationship between the Adjuvant Polysaccharide and O3 Antigen of Klebsiella

I. Nakashima, M. Mori, M. Ohta, 1981, Microbiology and immunology.

Further Studies of the Polysaccharide of Klebsiella pneumoniae Possessing Strong Adjuvanticity: I. Production of the Adjuvant Polysaccharide by Noncapsulated Mutant

I. Nakashima, F. Nagase, M. Mori, 1981, Microbiology and immunology.

Microbial Adjuvant and Autoimmunity

T. Yokochi, I. Nakashima, Jun-ya Asai, 1978, Microbiology and immunology.

Studies on the immune response in chickens I. Effect of various immunization procedures on the primary and secondary antibody responses to bovine serum albumin.

I. Nakashima, F. Nagase, N. Kato, 1978, Zeitschrift fur Immunitatsforschung. Immunobiology.

Studies on the immune response in chickens II. Functions of carrier-reactive cells in anti-hapten responses.

I. Nakashima, F. Nagase, N. Kato, 1978, Zeitschrift fur Immunitatsforschung. Immunobiology.

A new mouse model for autoimmune orchitis

T. Yokochi, I. Nakashima, Jun-ya Asai, 2004, Medical Microbiology and Immunology.

A new method for induction of experimental autoimmune uveoretinitis (EAU) in mice.

M. Mochizuki, I. Nakashima, H. Kawashima, 1990, Current eye research.

Adjuvant Activity of Klebsiella O3 Lipopolysaccharide: Comparative Study Using Defined Uniform Salt Forms

I. Nakashima, M. Ohta, N. Kato, 1984, Microbiology and immunology.

Adjuvant Activity of Klebsiella O3 Lipopolysaccharide

I. Nakashima, M. Ohta, N. Kato, 1984 .

Factors affecting experimental infection with Cryptococcus neoformans in mice with special reference to an endotoxic substance of C. neoformans

I. Nakashima, Takashi Kobayashi, O. Kato, 1975, Mycopathologia.

Histamine synthesis by non-mast cells through mitogen-dependent induction of histidine decarboxylase.

I. Nakashima, S. Suzuki, K. Yamashita, 1988, Immunology.

A novel RFP-RET transgenic mouse model with abundant eumelanin in the cochlea

K. Wakamatsu, S. Ito, I. Nakashima, 2004, Hearing Research.

The ret oncogene can induce melanogenesis and melanocyte development in Wv/Wv mice.

I. Nakashima, T. Iwamoto, M. Ohbayashi, 1992, Experimental cell research.

Human IgE antibody to the carbohydrate-containing third domain of chicken ovomucoid.

K. Shimokata, I. Nakashima, T. Matsuda, 1985, Biochemical and biophysical research communications.

Acrolein induces activation of the epidermal growth factor receptor of human keratinocytes for cell death

T. Miyata, A. Akhand, M. Kato, 2001, Journal of cellular biochemistry.

Nonspecific crossreacting antigen (NCA) is a major member of the carcinoembryonic antigen (CEA)-related gene family expressed in lung cancer.

K. Isobe, K. Shimokata, I. Nakashima, 1993, British Journal of Cancer.

Potent adjuvant action of lipopolysaccharides possessing the O-specific polysaccharide moieties consisting of mannans in antibody response against protein antigen.

I. Nakashima, F. Nagase, H. Ito, 1985, Cellular immunology.

Synthesis of a set of di- and tri-sulfated galabioses.

T. Yokochi, T. Yoshida, I. Nakashima, 2001, Carbohydrate research.

Complete Regression of Hereditary Melanoma in a Mouse Model by Repeated Hyperthermia Using Magnetite Cationic Liposomes

H. Honda, Takeshi Kobayashi, I. Nakashima, 2005 .

Induction of T lymphocyte apoptosis by treatment with glycyrrhizin.

M. Kato, I. Nakashima, T. Yokoyama, 1999, The American journal of Chinese medicine.

Modulation of endotoxin-induced histamine synthesis by cytokines in mouse bone marrow-derived macrophages

I. Nakashima, S. Takamatsu, K. Nakano, 1997, Inflammation Research.

Histamine synthesis by mouse T lymphocytes through induced histidine decarboxylase.

Y. Kitamura, I. Nakashima, K. Nakano, 1988, Immunology.

Sustained activation of c-jun-terminal kinase (JNK) is closely related to arsenic trioxide-induced apoptosis in an acute myeloid leukemia (M2)-derived cell line, NKM-1

T. Naoe, A. Akhand, I. Nakashima, 2003, Leukemia.

Paradoxical effects of LPS on the T-cell-independent type 2 anti-H-2 alloantigen antibody responses to allogeneic erythrocytes.

K. Shimokata, I. Nakashima, F. Nagase, 1984, Transplantation.

Experission of glutathione-S-transferases α and π in gastric cancer: a correlation with cisplatin resistance

Y. Kodera, K. Isobe, I. Nakashima, 2004, Cancer Chemotherapy and Pharmacology.

Studies on the immune response in chickens. IV. Generation of hapten-specific memory and absence of increase in carrier-specific helper memory in antibody response to sheep red blood cell antigen and its hapten-conjugate.

I. Nakashima, F. Nagase, N. Kato, 1983, Developmental and comparative immunology.

Dynamics of generation of antigen loss variants from L1210 murine leukemia clones detected by a tumor-specific T-cell clone.

T. Yokochi, T. Yoshida, I. Nakashima, 1987, Cancer research.

The immunosuppressive effect of fresh allogeneic bone graft in mice

I. Nakashima, N. Ishiguro, H. Iwata, 1997, International Orthopaedics.

Characterization of the immunoregulatory action of saikosaponin-d.

M. Kato, I. Nakashima, T. Iwamoto, 1994, Cellular immunology.

Demonstration of lipid A‐binding proteins on murine lymphoma cells using R‐mutant Gram‐negative bacteria as a detector

T. Yokochi, T. Yoshida, R. Inagi, 1990, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

FUT-175 as a potent inhibitor of C5/C3 convertase activity for production of C5a and C3a.

T. Miyata, R. Inagi, I. Nakashima, 1991, Immunology letters.

DonorIgh-linked genetic control of allotype-specific antibody response

Tomoaki Yoshida, K. Isobe, R. Inagi, 2006, Immunogenetics.

The donor cell type controls anti-hapten (fluorescein isothiocyanate) primary antibody response to hapten-modified syngeneic cells.

I. Nakashima, F. Nagase, N. Kato, 1982, Immunology letters.

Modulation of endotoxin-induced histamine synthesis by cytokines in mouse bone marrow-derived macrophages.

I. Nakashima, S. Takamatsu, K. Nakano, 1996, Journal of immunology.

Identification of RET Autophosphorylation Sites by Mass Spectrometry*

Masahide Takahashi, R. Taguchi, Y. Okuno, 2004, Journal of Biological Chemistry.

Nitric Oxide Controls Src Kinase Activity through a Sulfhydryl Group Modification-mediated Tyr-527-independent and Tyr-416-linked Mechanism*

A. Akhand, H. Suzuki, I. Nakashima, 1999, The Journal of Biological Chemistry.

Characterization of the Growth Factor Activity of Amniotic Fluid on Cells from Hematopoietic and Lymphoid Organs of Different Life Stages

K. Isobe, I. Nakashima, Z. Heidari, 1996, Microbiology and immunology.

Transforming growth factor-beta 1 enhances the generation of allospecific cytotoxic T lymphocytes.

I. Nakashima, N. Ishiguro, K. Isobe, 1993, Immunology.

Analysis of PI (phosphatidylinositol)‐anchoring antigens in a patient of paroxysmal nocturnal hemoglobinuria (PNH) reveals deficiency of 1F5 antigen (CD59), a new complement‐regulatory factor

R. Taguchi, I. Nakashima, Yasuhiro Funahashi, 1990, FEBS letters.

A protective role of interleukin-15 in a mouse model for systemic infection with herpes simplex virus.

T. Daikoku, I. Nakashima, Y. Yoshikai, 2000, Virology.

Effects of Semiconductor Laser Irradiation on Cultured Human Keratinocytes

I. Nakashima, A. Hayakawa, H. Tajiri, 1996 .

Inhibition of human complement-dependent cell lysis by bovine aortic endothelial cells transfected with membrane-bound complement-regulatory factor (DAF and HRF20) gene using a retroviral vector.

K. Isobe, I. Nakashima, H. Okada, 1996, European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes.

Genetic controls of T cell-independent Thy-1 alloantibody responses

Tomoaki Yoshida, K. Isobe, R. Inagi, 2004, Immunogenetics.

T cell maturation stage-linked heterogeneity of the glycosylphosphatidylinositol membrane anchor of Thy-1.

R. Taguchi, T. Yoshida, M. Kato, 1992, Immunobiology.

Ontogeny of the transplantation immunity of mice for rejecting ascitic allogeneic tumors.

I. Nakashima, F. Nagase, N. Kato, 1985, Developmental and comparative immunology.

Mode of alloantibody-mediated blockade of allo-sensitization for tumor allograft rejection.

K. Shimokata, T. Yoshida, I. Nakashima, 1989, Immunobiology.

1,4‐butanediyl‐bismethanethiosulfonate (BMTS) induces apoptosis through reactive oxygen species‐mediated mechanism

Md. Murshadul Hoque, A. Akhand, Y. Kawamoto, 2009, Journal of cellular biochemistry.

Interleukin-6 gene ablation in a transgenic mouse model of malignant skin melanoma.

C. Vallan, J. Weis, V. von Felbert, 2005, The American journal of pathology.

Linkage between melanocytic tumor development and early burst of Ret protein expression for tolerance induction in metallothionein-I/ret transgenic mouse lines

Wei Liu, Masahide Takahashi, K. Isobe, 1999, Oncogene.

Proliferation and neoplastic transformation of pigment cells in metallothionein/ret transgenic mice.

I. Nakashima, T. Iwamoto, M. Takahashi, 1992, Pigment cell research.

Genetic and stimulatory cell type requirements for inducing class I major histocompatibility complex alloantigen‐specific in vivo cytotoxic T cell immunity

K. Shimokata, K. Isobe, I. Nakashima, 1985, European journal of immunology.

Protective effect of hyperpigmented skin on UV-mediated cutaneous cancer development.

T. Tsuzuki, Masahide Takahashi, Y. Kawamoto, 2007, The Journal of investigative dermatology.

c-Kit-Targeting Immunotherapy for Hereditary Melanoma in a Mouse Model

Toyonori Tsuzuki, Khaled Hossain, Masashi Kato, 2004, Cancer Research.

T-cell-immunity-based inhibitory effects of orally administered herbal medicine juzen-taiho-to on the growth of primarily developed melanocytic tumors in RET-transgenic mice.

A. Akhand, Y. Kawamoto, M. Kato, 2001, The Journal of investigative dermatology.

Ultraviolet radiation induces both full activation of ret kinase and malignant melanocytic tumor promotion in RFP-RET-transgenic mice.

M. Kato, I. Nakashima, K. Takeda, 2000, The Journal of investigative dermatology.

Mapping of Melanoma Modifier Loci in RET Transgenic Mice

N. Zanesi, T. Dragani, A. Aloisi, 2000, Japanese journal of cancer research : Gann.

Further characterization of the Sho-saio-to-mediated anti-tumor effect on melanoma developed in RET-transgenic mice.

M. Kato, I. Nakashima, K. Isobe, 2000, The Journal of investigative dermatology.

Control of primary IgM antibody responses to H‐2 alloantigens by antigen‐bearing live B lymphocytes

K. Isobe, I. Nakashima, F. Nagase, 1982, European journal of immunology.

Mechanism of nitric oxide-dependent killing of Mycobacterium bovis BCG in human alveolar macrophages

S. Ichiyama, K. Shimokata, I. Nakashima, 1997, Infection and immunity.

Dynamics of Cytotoxic T Lymphocyte Precursors in Vivo Assessed by Change in the Radiation Sensitivity

K. Shimokata, T. Yoshida, I. Nakashima, 1988, Scandinavian journal of immunology.

Direct activation of Sendai virus (HVJ)-specific cell-mediated immunity of mice for second set rejection of the virus-infected syngeneic tumor by noninfectious virus-sensitized spleen cells.

T. Yoshida, I. Nakashima, F. Nagase, 1985, Immunology letters.

Induction of high-grade tumor-specific immunity in a host using a cytotoxic T-lymphocyte clone specific for a stable tumor antigen on murine leukemia L1210.

I. Nakashima, F. Nagase, K. Kawashima, 1988, Cancer research.

Inhibitory effect of herpes simplex virus infection to target cells on recognition of minor histocompatibility antigens by cytotoxic T lymphocytes.

I. Nakashima, A. Takatsuki, T. Morishima, 1990, Journal of immunology.

Redox-linked cell surface-oriented signaling for T-cell death.

Wei Liu, Jun Du, T. Miyata, 2002, Antioxidants & redox signaling.

Arsenite Induces Apoptosis of Murine T Lymphocytes Through Membrane Raft-Linked Signaling for Activation of c-Jun Amino-Terminal Kinase1

Wei Liu, A. Akhand, I. Nakashima, 2000, The Journal of Immunology.

Establishment of mouse oligodendrocyte/type-2 astrocyte lineage cell line by transfection with origin-defective simian virus 40 DNA.

T. Marunouchi, I. Nakashima, A. Suzumura, 1992, Cell structure and function.

Elucidation of the protein kinase C‐dependent apoptosis pathway in distinct subsets of T lymphocytes in MRL‐lpr/lpr mice

K. Isobe, I. Nakashima, H Hidaka, 1995, European journal of immunology.

Feedback suppression of staphylococcal enterotoxin-stimulated T-lymphocyte proliferation by macrophages through inductive nitric oxide synthesis

I. Nakashima, K. Isobe, Ken-ichi Isobe, 1992, Infection and immunity.

Intact and subcellular form of thymocytes of rats are exceptionally immunogenic in mice for inducing anti-Thy-1 T cell-independent class 2 antibody responses.

I. Nakashima, F. Nagase, P. Lake, 1983, Immunology letters.

A short peptide derived from the antisense homology box of Fas ligand induces apoptosis in anti-Fas antibody-insensitive human ovarian cancer cells

H. Suzuki, I. Nakashima, A. Hayakawa, 2000, Apoptosis.

Nuclear localization of antigens detected by a monoclonal antibody against a synthetic peptide of rfp finger protein.

R. Ueda, T. Seito, I. Nakashima, 1990, Hybridoma.

Direct evidence of involvement of glycosylphosphatidylinositol‐anchored proteins in the heavy metal‐mediated signal delivery into T lymphocytes

R. Taguchi, K. Isobe, I. Nakashima, 1995, FEBS letters.

Dissociated control by glycyrrhizin of proliferation and IL-2 production of murine thymocytes.

T. Yokochi, M. Kato, I. Nakashima, 1995, Cellular Immunology.

Preferential development of pre‐B lymphomas with drastically down‐regulated N‐myc in the Eμ‐ret transgenic mice

M. Ichihara, K. Isobe, I. Nakashima, 1991, European journal of immunology.

Introduction of α(1,2)‐fucosyltransferase and its effect on a‐Gal epitopes in transgenic pig

R. Kannagi, I. Nakashima, H. Okada, 1996 .

5‐aminolaevulinic acid photodynamic therapy in a transgenic mouse model of skin melanoma

C. Vallan, J. Weis, V. von Felbert, 2005, Experimental dermatology.

Evidence for posttranscriptional regulation of transgenic protein kinase C–alpha in T cells

H. Hidaka, I. Nakashima, T. Iwamoto, 1994, Journal of cellular biochemistry.

In vitro and in vivo expression of inducible nitric oxide synthase during experimental endotoxemia: Involvement of other cytokines

K. Isobe, I. Nakashima, K. Aono, 1997, Journal of cellular biochemistry.

Caspase activation is accelerated by the inhibition of arsenite-induced, membrane rafts-dependent Akt activation.

Jun Du, A. Akhand, Y. Kawamoto, 2003, Free radical biology & medicine.

Differential Regulation of MMP‐9 and TIMP‐2 Expression in Malignant Melanoma Developed in Metallothionein/RET Transgenic Mice

N. Asai, I. Nakashima, T. Iwashita, 1999, Japanese journal of cancer research : Gann.

Establishment and characterisation of human carcinoembryonic antigen transgenic mice.

K. Shimokata, I. Nakashima, S. Oikawa, 1991, British Journal of Cancer.

Clustered cysteine residues in the kinase domain of v-Src: critical role for protein stability, cell transformation and sensitivity to herbimycin A

S. Matsuda, I. Nakashima, T. Senga, 2000, Oncogene.

Dynamics of soluble adhesion molecule levels in patients with pollinosis.

M. Kato, I. Nakashima, T. Hattori, 1996, Archives of otolaryngology--head & neck surgery.

Nitric oxide releasing reagent, S‐nitroso‐N‐acetylpenicillamine, enhances the expression of manganese superoxide dismutase mRNA in rat vascular smooth muscle cells

K. Isobe, I. Nakashima, M. Hirai, 1996, Journal of cellular biochemistry.

A murine model of experimental autoimmune lens-induced uveitis using Klebsiella O3 lipopolysaccharide as a potent immunological adjuvant.

T. Yokochi, I. Nakashima, J. Asai, 1993, International journal of experimental pathology (Print).

Strong adjuvanticity of bacterial lipopolysaccharides possessing the homopolysaccharides consisting of mannose as the O-specific polysaccharide chains.

T. Yokochi, I. Nakashima, F. Nagase, 1985, Medical microbiology and immunology.

Experimental autoimmune hemolytic anemia in mice induced by repeated immunization with ultrasonicated syngeneic erythrocytes together with Klebsiella O3 lipopolysaccharide.

T. Yokochi, I. Nakashima, N. Kato, 1984, Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society.

Experimental autoimmune hepatitis in mice after immunization with syngeneic liver proteins together with the polysaccharide of Klebsiella pneumoniae.

T. Yokochi, I. Nakashima, S. Kakumu, 1983, Gastroenterology.

Enhancement of nitric oxide production from activated macrophages by a purified form of ginsenoside (Rg1).

I. Nakashima, K. Kiuchi, K. Isobe, 1995, The American journal of Chinese medicine.

High‐grade tumor‐specific immunity induced by L1210 leukemia variants obtained from the culture of L1210 cells fused with Lesch‐Nyhan fibroblasts

S. Saga, K. Isobe, K. Yamada, 1983, International journal of cancer.

The herbal medicine sho-saiko-to inhibits the growth of malignant melanoma cells by upregulating Fas-mediated apoptosis and arresting cell cycle through downregulation of cyclin dependent kinases.

M. Kato, H. Suzuki, I. Nakashima, 1998, International journal of oncology.

Involvement of MEKK1/ERK/P21Waf1/Cip1 signal transduction pathway in inhibition of IGF‐I‐mediated cell growth response by methylglyoxal

Jun Du, T. Miyata, A. Akhand, 2003, Journal of cellular biochemistry.

Production of anti-self-h-2 antibodies by C3D2F1 mice hyperimmune to L cell/L1210 hybrids and L1210 leukemia cells.

M. Ogura, K. Isobe, K. Yamada, 1982, Cellular immunology.

Simultaneous development of humoral and cellular tumor-specific immunity against L1210 mouse leukemia.

T. Yokochi, K. Yamada, I. Nakashima, 1985, Leukemia research.

Local levels of soluble tumor necrosis factor receptors in patients with allergic rhinitis are regulated by amount of antigen.

M. Kato, I. Nakashima, Y. Kato, 2000, Archives of Otolaryngology - Head and Neck Surgery.

EOSINOPHIL CATIONIC PROTEIN AND PROPHYLACTIC TREATMENT IN POLLINOSE IN NATURAL ALLERGEN PROVOCATION

M. Kato, I. Nakashima, N. Yanagita, 1994, The British journal of clinical practice.

Immune reactivity of allogeneically pregnant mice to paternal MHC antigens on fetal and placental cells assessed by second set rejection of ascites tumor cells.

I. Nakashima, F. Nagase, S. Goto, 1985, Journal of reproductive immunology.

Predominant activation of extrathymic T cells during melanoma development of metallothionein/ret transgenic mice.

I. Nakashima, T. Iwamoto, H. Watanabe, 1994, Cellular immunology.

Molecular and functional identification and purification of complement component factor D from urine of patients with chronic renal failure.

T. Miyata, R. Inagi, I. Nakashima, 1990, Molecular immunology.

Induction and characterization of minor histocompatibility antigens. Specific primary cytotoxic T lymphocyte responses in vitro.

T. Yoshida, I. Nakashima, T. Iwamoto, 1988, Journal of immunology.

Transgenic Mouse Models for Immunosenescence

K. Isobe, Y. Kawamoto, I. Nakashima, 2003 .

Protein kinase C alpha-mediated chronic signal transduction for immunosenescence.

H. Hidaka, A. Akhand, M. Kato, 1997, Journal of Immunology.

Expression of carcinoembryonic antigen (CEA) and nonspecific crossreacting antigen (NCA) in gastrointestinal cancer; the correlation with degree of differentiation.

Y. Kodera, K. Isobe, I. Nakashima, 1993, British Journal of Cancer.

Interferon and Cytotoxic Factor (Cytotoxin) Released in the Blood of Mice Infected with Mycobacterium bovis BCG

T. Yokochi, I. Nakashima, F. Nagase, 1980, Microbiology and immunology.

Establishment and characterization of a malignant melanocytic tumor cell line expressing the ret oncogene.

M. Matsuyama, I. Nakashima, T. Iwamoto, 1992, Oncogene.

Quantitative analysis of antigen for the induction of tolerance in carcinoembryonic antigen transgenic mice.

K. Shimokata, I. Nakashima, K. Isobe, 1992, Immunology.

Nitric oxide production from a macrophage cell line: Interaction with autologous and allogeneic lymphocytes

K. Isobe, I. Nakashima, 1993, Journal of cellular biochemistry.

Primary antibody responses to hapten‐modified syngeneic cells: exceptional immunogenicity of erythrocytes

I. Nakashima, F. Nagase, N. Kato, 1981, European Journal of Immunology.

Genomic cloning and promoter analysis of the GAHSP40 gene

K. Isobe, I. Nakashima, F. Hamajima, 2002, Journal of cellular biochemistry.

Establishment and characterisation of human carcinoembryonic antigen transgenic mice.

K. Shimokata, K. Isobe, I. Nakashima, 1991, British Journal of Cancer.

Molecular basis of evolutionary loss of the alpha 1,3-galactosyltransferase gene in higher primates.

T. Starzl, R. Kannagi, J. Fung, 2002, The Journal of biological chemistry.

Evolution of humans outside the genome.

I. Nakashima, 2005, Nagoya journal of medical science.

Control of T-cell-dependent antibody responses of mice to rat antigens by donor cell types.

I. Nakashima, F. Nagase, N. Kato, 1983, Immunology letters.

Kupffer cells cytotoxicity against hepatoma cells is related to nitric oxide.

I. Nakashima, K. Aono, K. Isobe, 1994, Biochemical and biophysical research communications.

Endotoxic substance of cryptococcus neoformans

I. Nakashima, Takashi Kobayashi, N. Kato, 1974, Mycopathologia et mycologia applicata.

Differential display analysis of murine collagen‐induced arthritis: cloning of the cDNA‐encoding murine ATPase inhibitor

I. Nakashima, N. Ishiguro, H. Iwata, 1997, Immunology.