Haiyan Wang

发表

Dominant-negative Suppression of HNF-1α Results in Mitochondrial Dysfunction, INS-1 Cell Apoptosis, and Increased Sensitivity to Ceramide-, but Not to High Glucose-induced Cell Death*

M. Byrne, H. Düssmann, D. Kögel, 2002, The Journal of Biological Chemistry.

Activation of the Insulin Gene Promoter through a Direct Effect of Hepatocyte Nuclear Factor 4α*

C. Wollheim, Haiyan Wang, J. Bar-Tana, 2002, The Journal of Biological Chemistry.

Transcriptional Regulation of X-Box-binding Protein One (XBP1) by Hepatocyte Nuclear Factor 4α (HNF4Α) Is Vital to Beta-cell Function*

F. Urano, J. Mills, C. Wollheim, 2016, The Journal of Biological Chemistry.

Does chasing selected 'Fox' to the nucleus prevent diabetes?

C. Wollheim, Haiyan Wang, 2005, Trends in molecular medicine.

Experimental models of transcription factor-associated maturity-onset diabetes of the young.

L. Otten, C. Wollheim, Haiyan Wang, 2002, Diabetes.

Hepatocyte nuclear factor-1α modulates pancreatic β-cell growth by regulating the expression of insulin-like growth factor-1 in INS-1 cells

Y. Matsuzawa, R. Bucala, C. Wollheim, 2002 .

Involvement of Dynamin-Related Protein 1 in Free Fatty Acid-Induced INS-1-Derived Cell Apoptosis

Haiyan Wang, Liang Peng, J. Lou, 2012, PloS one.

β-Cell-Targeted Expression of a Dominant-Negative Hepatocyte Nuclear Factor-1α Induces a Maturity-Onset Diabetes of the Young (MODY)3-Like Phenotype in Transgenic Mice.

C. Wollheim, Haiyan Wang, H. Ishihara, 2001, Endocrinology.

The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects β-cells against stress-induced apoptosis.

P. Marchetti, F. Pattou, C. Wollheim, 2018, Human molecular genetics.

Hepatocyte nuclear factor-1alpha modulates pancreatic beta-cell growth by regulating the expression of insulin-like growth factor-1 in INS-1 cells.

Y. Matsuzawa, R. Bucala, C. Wollheim, 2002, Diabetes.

Pdx1 Level Defines Pancreatic Gene Expression Pattern and Cell Lineage Differentiation*

C. Wollheim, Haiyan Wang, H. Ishihara, 2001, The Journal of Biological Chemistry.

Foxa2 (HNF3β) Controls Multiple Genes Implicated in Metabolism-Secretion Coupling of Glucose-induced Insulin Release*

Haiyan Wang, C. Wollheim, Haiyan Wang, 2002, The Journal of Biological Chemistry.

The MODY1 Gene for Hepatocyte Nuclear Factor 4 (cid:2) and a Feedback Loop Control COUP-TFII Expression in Pancreatic Beta Cells (cid:1)

M. Vasseur-Cognet, C. Wollheim, D. Scott, 2008 .

Characterization of Pancreatic Transcription Factor Pdx-1 Binding Sites Using Promoter Microarray and Serial Analysis of Chromatin Occupancy*

K. Kaestner, S. McWeeney, P. White, 2007, Journal of Biological Chemistry.

The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation.

H. Kasai, Y. Matsuzawa, I. Shimomura, 2005, Cell metabolism.

Hepatocyte Nuclear Factor 4α Regulates the Expression of Pancreatic β-Cell Genes Implicated in Glucose Metabolism and Nutrient-induced Insulin Secretion*

C. Wollheim, Haiyan Wang, P. Antinozzi, 2000, The Journal of Biological Chemistry.

Acute Glucose Intolerance in Insulinoma Cells with Unbalanced Overexpression of Glucokinase*

Haiyan Wang, P. Iynedjian, H. Wang, 1997, The Journal of Biological Chemistry.

ChREBP Rather than USF2 Regulates Glucose Stimulation of Endogenous L-pyruvate Kinase Expression in Insulin-secreting Cells*

C. Wollheim, Haiyan Wang, 2002, The Journal of Biological Chemistry.

The Transcription Factor SREBP-1c Is Instrumental in the Development of β-Cell Dysfunction*

C. Wollheim, Haiyan Wang, P. Antinozzi, 2003, The Journal of Biological Chemistry.

ER stress and SREBP-1 activation are implicated in β-cell glucolipotoxicity

C. Wollheim, Haiyan Wang, G. Kouri, 2005, Journal of Cell Science.

Molecular targets of a human HNF1α mutation responsible for pancreatic β‐cell dysfunction

C. Wollheim, Haiyan Wang, P. Antinozzi, 2000 .

Correction: Involvement of Dynamin-Related Protein 1 in Free Fatty Acid-Induced INS-1-Derived Cell Apoptosis

Haiyan Wang, Liang Peng, J. Lou, 2013, PLoS ONE.

Haiyan Wang, Liang Peng, Mei Xu, 2011, International journal of molecular medicine.

C. Wollheim, Haiyan Wang, J. Lou, 2009, The international journal of biochemistry & cell biology.

Desensitization of Mitochondrial Ca2+ and Insulin Secretion Responses in the Beta Cell*

C. Wollheim, Haiyan Wang, P. Maechler, 1998, The Journal of Biological Chemistry.

Continuous monitoring of ATP levels in living insulin secreting cells expressing cytosolic firefly luciferase

C. Wollheim, Haiyan Wang, P. Maechler, 1998, FEBS letters.

Dominant‐negative suppression of HNF‐1α function results in defective insulin gene transcription and impaired metabolism‐secretion coupling in a pancreatic β‐cell line

C. Wollheim, Haiyan Wang, P. Maechler, 1998, The EMBO journal.

TRB3 is implicated in glucotoxicity- and ER-stress-induced beta-cell apoptosis

C. Wollheim, Haiyan Wang, J. Lou, 2008 .

TRIB3 is implicated in glucotoxicity- and oestrogen receptor-stress-induced b -cell apoptosis

C. Wollheim, Haiyan Wang, J. Lou, 2008 .

Liver-specific Enhancer of the Glucokinase Gene*

Haiyan Wang, P. Iynedjian, K. Nazaryan, 1996, The Journal of Biological Chemistry.

The MODY1 Gene for Hepatocyte Nuclear Factor 4α and a Feedback Loop Control COUP-TFII Expression in Pancreatic Beta Cells

M. Vasseur-Cognet, C. Wollheim, D. Scott, 2008, Molecular and Cellular Biology.

The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {beta}-cells against stress-induced apoptosis.

P. Marchetti, F. Pattou, C. Wollheim, 2011, Human molecular genetics.

Hepatic Nuclear Factor 1α (HNF1α) Dysfunction Down-regulates X-box-binding Protein 1 (XBP1) and Sensitizes β-Cells to Endoplasmic Reticulum Stress*

A. Wiederkehr, C. Wollheim, Haiyan Wang, 2011, The Journal of Biological Chemistry.

ER stress and SREBP-1 activation are implicated in beta-cell glucolipotoxicity.

C. Wollheim, Haiyan Wang, G. Kouri, 2005, Journal of cell science.

HNF 3 β ) controls multiple genes implicated in metabolism-secretion coupling of glucose-induced insulin release

C. Wollheim, Haiyan Wang, M. Iezzi, 2002 .

Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation.

C. Wollheim, Haiyan Wang, M. Iezzi, 2010, Biochimica et biophysica acta.

Human Krüppel-like factor 11 differentially regulates human insulin promoter activity in β-cells and non-β-cells via p300 and PDX1 through the regulatory sites A3 and CACCC box

C. Wollheim, Haiyan Wang, J. Seufert, 2012, Molecular and Cellular Endocrinology.

Human Krüppel-like factor 11 differentially regulates human insulin promoter activity in β-cells and non-β-cells via p 300 and PDX 1 through the regulatory sites A 3 and CACCC box PERAKAKIS

C. Wollheim, Haiyan Wang, J. Seufert, 2017 .

Modulation of glucose responsiveness of insulinoma beta-cells by graded overexpression of glucokinase.

Haiyan Wang, P. Iynedjian, H. Wang, 1997, Proceedings of the National Academy of Sciences of the United States of America.

ER stress and SREBP-1 activation are implicated in β-cell glucolipotoxicity

C. Wollheim, Haiyan Wang, G. Kouri, 2005, Journal of Cell Science.

ER stress and SREBP-1 activation are implicated in β-cell glucolipotoxicity

C. Wollheim, Haiyan Wang, G. Kouri, 2005, Journal of Cell Science.

Involvement of the Ca2+-responsive transactivator in high glucose-induced β-cell apoptosis.

Haiyan Wang, Liang Peng, J. Lou, 2013, The Journal of endocrinology.

Involvement of the Ca 2 C -responsive transactivator in high glucose-induced b -cell apoptosis

Haiyan Wang, Liang Peng, Shiqing Xu, 2013 .

Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells.

C. Wollheim, L. Drewes, Haiyan Wang, 1999, The Journal of clinical investigation.

Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells

S. Theander, P. Halban, C. Wollheim, 2005, Diabetologia.

Haiyan Wang, Liang Peng, Mei Xu, 2011, International Journal of Molecular Medicine.

Expression of alpha-1 proteinase inhibitor in human islet microvascular endothelial cells.

C. Wollheim, P. Morel, Haiyan Wang, 1999, Diabetes.