Ben D. Chen

发表

Activation of the MEK/MAPK pathway is involved in bryostatin1-induced monocytic differenciation and up-regulation of X-linked inhibitor of apoptosis protein.

Xiaohua Li, Hong Lin, Catheryne Chen, 2002, Experimental cell research.

XK469, a novel antitumor agent, inhibits signaling by the MEK/MAPK signaling pathway

Hong Lin, Ben D. Chen, B. Subramanian, 2002, Cancer Chemotherapy and Pharmacology.

Increased half-life and enhanced potency of Fc-modified human PCSK9 monoclonal antibodies in primates

Ben D. Chen, Hua Li, Yijun Shen, 2017, PloS one.

Differentiation-Associated Expression of Conventional Protein Kinase C Isoforms in Primary Cultures of Bone Marrow Cells Induced by M-CSF and G-CSF.

Xiaohua Li, Ben D. Chen, H. Meng, 2009, American journal of biomedical sciences.

Lineage-dependent NF-kappaB activation contributes to the resistance of human macrophages to apoptosis.

Yan Li, B. Shen, Jiyan Zhang, 2003, The hematology journal : the official journal of the European Haematology Association.

Histone Deacetylase Inhibitor M344 Inhibits Cell Proliferation and Induces Apoptosis in Human THP-1 Leukemia Cells.

Xiaohua Li, Ben D. Chen, 2009, American journal of biomedical sciences.

Erythromycin inhibits wear debris‐induced inflammatory osteolysis in a murine model

Ben D. Chen, W. Ren, P. Wooley, 2006, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-X(L) [(-)-gossypol] against diffuse large cell lymphoma.

Shaomeng Wang, R. Mohammad, Jianyong Chen, 2005, Molecular cancer therapeutics.

Effect of Danshen aqueous extract on serum hs-CRP, IL-8, IL-10, TNF-α levels, and IL-10 mRNA, TNF-α mRNA expression levels, cerebral TGF-β1 positive expression level and its neuroprotective mechanisms in CIR rats

Ben D. Chen, Xiao-yan Yang, Xuebing Liang, 2013, Molecular Biology Reports.

Characterization of MW06, a human monoclonal antibody with cross-neutralization activity against both SARS-CoV-2 and SARS-CoV

M. Zhang, Da-di Zeng, An Wang, 2021, mAbs.

A Novel Leflunomide Analog, UTL-5b (GBL-5b), Suppresses JAK3, MAP3K2, and LITAF Genes

J. Shaw, Ben D. Chen, B. Palfey, 2011 .

The Effect and Mechanism of Lipoxin A4 on Neutrophil Function in LPS-Induced Lung Injury.

Ben D. Chen, Xin Hu, Hong-Xia Mei, 2022, Inflammation.

The Effect and Mechanism of Lipoxin A4 on Neutrophil Function in LPS-Induced Lung Injury

Ben D. Chen, Wen-Chi Pan, Xin Hu, 2021, Inflammation.

Mitotic arrest induced by XK469, a novel antitumor agent, is correlated with the inhibition of cyclin B1 ubiquitination

F. Valeriote, Hong Lin, Ben D. Chen, 2002, International journal of cancer.

Enhancement of Bone Marrow CD41+ Megakaryocytes as well as Modulation of TNF-a, IL-12, and IL-5 by a Novel Small Molecule, UTL-5g, in Mice Treated with Cisplatin

J. Shaw, F. Valeriote, Ben D. Chen, 2015 .

T0001, a variant of TNFR2-Fc fusion protein, exhibits improved Fc effector functions through increased binding to membrane-bound TNFα

Ben D. Chen, Hua Li, Chun-xia Gu, 2017, PloS one.

Anti-inflammatory and Anti-arthritic Effects of a Novel Leflunomide Analogue, UTL-5b (GBL-5b).

J. Shaw, Ben D. Chen, P. Wooley, 2011, American journal of biomedical sciences.

Anti-inflammatory and Anti-arthritic Effects of a Novel Leflunomide Analogue , UTL-5 b ( GBL-5 b )

J. Shaw, Ben D. Chen, P. Wooley, 2011 .

The Unexpected G 0 / G 1 Cell Cycle Status of Mobilized Hematopoietic Stem Cells From Peripheral Blood

Ben D. Chen, A. Tsukamoto, D. Sasaki, 1997 .

Prevention of colorectal cancer using COX-2 inhibitors: basic science and clinical applications.

Ben D. Chen, A. Chu, T. Chou, 2004, Frontiers in bioscience : a journal and virtual library.

Using a simple HPLC approach to identify the enzymatic products of UTL-5g, a small molecule TNF-α inhibitor, from porcine esterase and from rabbit esterase.

Yiguan Zhang, J. Shaw, F. Valeriote, 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Ben D. Chen, Xiao-yan Yang, Xuebing Liang, 2013, Molecular Biology Reports.

Erythromycin inhibits wear debris‐induced osteoclastogenesis by modulation of murine macrophage NF‐κB activity

Ben D. Chen, W. Ren, P. Wooley, 2004, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Prospective of colon cancer treatments and scope for combinatorial approach to enhanced cancer cell apoptosis.

J. Shaw, Ben D. Chen, Sohel H. Quazi, 2013, Critical reviews in oncology/hematology.

Preclinical Studies of TW-37, a New Nonpeptidic Small-Molecule Inhibitor of Bcl-2, in Diffuse Large Cell Lymphoma Xenograft Model Reveal Drug Action on Both Bcl-2 and Mcl-1

Sanjeev Banerjee, Shaomeng Wang, R. Mohammad, 2007, Clinical Cancer Research.

Preclinical Studies ofTW-37, a New Nonpeptidic Small-Molecule Inhibitor of Bcl-2, in Diffuse Large Cell Lymphoma Xenograft Model Reveal Drug Action on Both Bcl-2 andMcl-1

Sanjeev Banerjee, R. Mohammad, Z. Nikolovska-Coleska, 2007 .

SMI of Bcl-2 TW-37 is active across a spectrum of B-cell tumors irrespective of their proliferative and differentiation status

A. Azmi, R. Mohammad, Ben D. Chen, 2009, Journal of hematology & oncology.

Identification of the Metabolites of a Novel Anti-MRSA Compound, Kaempferol-3-O-Alpha-L-(2″,3″-di-p-coumaroyl)rhamnoside (KCR), Extracted from American Sycamore

J. Shaw, F. Valeriote, Ben D. Chen, 2018 .

HPLC Plasma Assay of a Novel Anti-MRSA Compound, Kaempferol-3-O-Alpha-L-(2″,3″-di-p-coumaroyl)rhamnoside, from Sycamore Leaves

Yiguan Zhang, J. Shaw, F. Valeriote, 2015, Natural product communications.

Pretreatment with A Small-Molecule Tumor Necrosis Factor-Alpha (TNF-α) Inhibitor, UTL-5g, Reduced Radiation-Induced Acute Liver Toxicity in Mice

J. Shaw, F. Valeriote, Ben D. Chen, 2012 .

Phosphoproteome and transcription factor activity profiling identify actions of the anti-inflammatory agent UTL-5g in LPS stimulated RAW 264.7 cells including disrupting actin remodeling and STAT-3 activation.

Nicholas J. Carruthers, Xiaohua Gao, J. Shaw, 2017, European journal of pharmacology.

The Active Metabolite of UTL-5g, 5-Methylisoxazole-3-Carboxylic Acid, is Anti-Inflammatory and Reduces Doxorubicin-Induced Cardiac Toxicity

Xiaohua Gao, Yiguan Zhang, J. Shaw, 2016 .

UTL-5g Lowers Levels of TGF-Î² and TNF-Î± Elevated by Lung Irradiation and Does Not Affect Tumor-response to Irradiation

Stephen L. Brown, J. Shaw, F. Valeriote, 2014 .

UTL-5g Lowers Elevated Blood Levels of TNF-a and TGF-? and Increases Survival Rates in Animals Treated with LPS/D-(+)-galactosamine

Yiguan Zhang, J. Shaw, F. Valeriote, 2014 .

The small-molecule TNF-alpha modulator, UTL-5g, reduces side effects induced by cisplatin and enhances the therapeutic effect of cisplatin in vivo.

J. Shaw, F. Valeriote, Ben D. Chen, 2011, Journal of experimental therapeutics and oncology.

The small-molecule TNF-α inhibitor, UTL-5g, delays deaths and increases survival rates for mice treated with high doses of cisplatin

J. Shaw, Ben D. Chen, J. Media, 2013, Cancer Chemotherapy and Pharmacology.

Comparison of two molecular scaffolds, 5-methylisoxazole-3-carboxamide and 5-methylisoxazole-4-carboxamide.

Yiguan Zhang, J. Shaw, Ben D. Chen, 2014, Current pharmaceutical design.

Metabolism studies of a small-molecule tumor necrosis factor-alpha (TNF-α) inhibitor, UTL-5b (GBL-5b)

J. Shaw, F. Valeriote, Ben D. Chen, 2011, European Journal of Drug Metabolism and Pharmacokinetics.

Synthesis and Biological Evaluation of Novel N-phenyl-5-carboxamidyl Isoxazoles as Potential Chemotherapeutic Agents for Colon Cancer.

Hao Jiang, J. Shaw, F. Valeriote, 2012, American journal of biomedical sciences.

Metabolism studies of a small-molecule tumor necrosis factor-alpha (TNF-α) inhibitor, UTL-5b (GBL-5b)

J. Shaw, F. Valeriote, Ben D. Chen, 2012, European Journal of Drug Metabolism and Pharmacokinetics.

Macrophage activation by interferon α + β is associated with a loss of proliferative capacity: Role of interferon α + β in the regulation of macrophage proliferation and function

Ben D. Chen, F. Najor, 1987 .

Protectin DX promotes the inflammatory resolution via activating COX-2/L-PGDS-PGD2 and DP1 receptor in acute respiratory distress syndrome

Ben D. Chen, Mei-Lin Lin, Xin Hu, 2021, International Immunopharmacology.

Characterization of neutralizing antibody with prophylactic and therapeutic efficacy against SARS-CoV-2 in rhesus monkeys

An Wang, J. Min, Ben D. Chen, 2020, Nature Communications.

Effect of Platelet-rich Plasma on Implant Bone Defects in Rabbits Through the FAK/PI3K/AKT Signaling Pathway

Ben D. Chen, Wei Liu, Yu-guang Shi, 2019, Open life sciences.

Effect of platelet-rich plasma on the implant bone defects in rabbits through FAK/PI3K/AKT signaling pathway

Ben D. Chen, Wei Liu, Yu-guang Shi, 2018 .

LncRNA papillary thyroid carcinoma susceptibility candidate 3 (PTCSC3) regulates the proliferation of human periodontal ligament stem cells and toll-like receptor 4 (TLR4) expression to improve periodontitis

Ben D. Chen, Ting Ke, Wei Liu, 2019, BMC Oral Health.

The enhancement of TRAIL-induced apoptosis sensitivity of oral cancer Ca 9-22 cells by overexpressing RASSF 5 A

Ben D. Chen, Wei Liu, Youyang Zheng, 2017 .

Cleavage of Bcl-2 Protein by Activated Caspase-3 Is Associated with Inactivation of Lyn(p53/56) Kinase Activity in Human M-07e Leukemic Cells during Apoptosis.

Ben D. Chen, Ming Yu, Y. Lan, 2000, Zhongguo shi yan xue ye xue za zhi.