B. Mirkin

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Doxorubicin resistant neuroblastoma cells secrete factors that activate AKT and attenuate cytotoxicity in drug-sensitive cells.

M. Emran, A. Rebbaa, B. Mirkin, 2002, Cancer letters.

Mitogenic and apoptotic actions of epidermal growth factor on neuroblastoma cells are concentration-dependent.

B. Mirkin, B. Chiu, M. Madonna, 2006, The Journal of surgical research.

High pressure liquid chromatographic determination of hydrochlorothiazide in human serum and urine.

A. Sinaiko, B. Mirkin, M. W. Anders, 1976, Analytical chemistry.

Anti-Cancer Effect of HIV-1 Viral Protein R on Doxorubicin Resistant Neuroblastoma

R. Zhao, B. Mirkin, D. Liang, 2010, PloS one.

Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism.

S. Mousa, A. Rebbaa, B. Mirkin, 2009, American journal of physiology. Cell physiology.

Therapeutic agents for pediatric hypertension.

A. Sinaiko, B. Mirkin, 1977, Pediatric annals.

Pediatric hypertension: current therapeutic considerations.

A. Sinaiko, B. Mirkin, 1976, Pediatric annals.

Prevention of cyclophosphamide‐induced antidiuresis by furosemide infusion

B. Mirkin, T. Green, 1981, Clinical pharmacology and therapeutics.

Effect of catecholamines on the responses of the nictitating membrane to nervous stimulation in cats treated with reserpine

B. Mirkin, U. V. von Euler, 1963, The Journal of physiology.

Biological maturation and β-adrenergic effectors: development of β-adrenergic receptors in rabbit heart

B. Mirkin, J. Sheppard, W. Schumacher, 2004, Molecular and Cellular Biochemistry.

Familial pyrimidinemia and pyrimidinuria associated with severe fluorouracil toxicity.

M. Tuchman, B. Mirkin, D. Kiang, 1985, The New England journal of medicine.

Retroviral transfer of the β‐nerve growth factor gene into murine neuroectodermal tumor cells modulates cell proliferation rate, neurite formation, and NGF binding site expression

B. Mirkin, R. Castellon, Bernard L. Mirkin, 2000, Journal of neuroscience research.

Factors Secreted by Human Neuroblastoma Mediate Doxorubicin Resistance by Activating STAT3 and Inhibiting Apoptosis

A. Rebbaa, B. Mirkin, P. Chou, 2001, Molecular medicine.

Efficacy and safety of captopril in the treatment of severe childhood hypertension: report of the International Collaborative Study Group.

B. Mirkin, T. J. Newman, 1985, Pediatrics.

Z-4',5'-didehydro-5'-deoxy-5'-fluoroadenosine (MDL 28,842), an irreversible inhibitor of S-adenosylhomocysteine hydrolase, suppresses proliferation of cultured keratinocytes and squamous carcinoma cell lines.

A. Paller, B. Mirkin, S. L. Arnsmeier, 1993, Cancer research.

Effect of neonatal sympathectomy with 6-hydroxydopamine on reactivity of the renin-angiotensin system in spontaneously hypertensive rats.

A. Sinaiko, B. Mirkin, M. Cooper, 1980, Clinical science.

Epidermal growth factor can induce apoptosis in neuroblastoma.

B. Mirkin, B. Chiu, M. Madonna, 2007, Journal of pediatric surgery.

Isoproterenol‐Evoked Renin Release from the in Situ Perfused Kidney: Dose‐Response Characteristics in Spontaneously Hypertensive and Normotensive Wistar Rats

B. Mirkin, 1978, Circulation research.

Inhibition of DNA methyltransferase reverses cisplatin induced drug resistance in murine neuroblastoma cells.

B. Mirkin, Y. Qiu, R. S. Dwivedi, 2005, Cancer detection and prevention.

Factors influencing the selective secretion of adrenal medullary hormones.

B. Mirkin, 1961, The Journal of pharmacology and experimental therapeutics.

Increased IMP dehydrogenase gene expression in solid tumor tissues and tumor cell lines

F. Collart, B. Mirkin, E. Huberman, 1992 .

Drug therapy and the developing human: who cares?

B. Mirkin, 1975, Clinical research.

Emergency drug doses for infants and chldren

R. Kauffman, R. Roberts, B. Rumack, 1988 .

The role of histone acetylation versus DNA damage in drug-induced senescence and apoptosis

A. Rebbaa, B. Mirkin, F. Chu, 2006, Cell Death and Differentiation.

Differential expression of DNA-methyltransferases in drug resistant murine neuroblastoma cells.

B. Mirkin, Y. Qiu, R. S. Dwivedi, 2002, Cancer detection and prevention.

Effect of adenosine analogues on protein carboxylmethyltransferase, S-adenosylhomocysteine hydrolase, and ribonucleotide reductase activity in murine neuroblastoma cells.

B. Mirkin, D. Barten, R. O'dea, 1987, Cancer research.

Effect of nerve growth factor on C‐1300 murine neuroblastoma tumor growth and catecholamine content in neonatally sympathectomized mice

B. Mirkin, D. Fink, 1991, Journal of neuroscience research.

Urinary corticosteriod and diphenylhydantoin metabolite patterns in neonates exposed to anticonvulsant drugs in utero

J. Reynolds, B. Mirkin, Bernard L. Mirkin, 1973, Clinical pharmacology and therapeutics.

Novel action of epidermal growth factor on caspase 3 and its potential as a chemotherapeutic adjunct for neuroblastoma.

B. Mirkin, B. Chiu, M. Madonna, 2007, Journal of pediatric surgery.

Suppressive effect of elongation factor 2 on apoptosis induced by HIV-1 viral protein R

R. Zhao, B. Mirkin, D. Liang, 2006, Apoptosis.

Catecholamine Binding Protein: Binding of Tritium to a Specific Protein Fraction of Human Plasma following in vitro Incubation with Tritiated Noradrenaline

B. Mirkin, R. Ulstrom, DAVID M. Brown, 1966, Nature.

Placental transfer and neonatal elimination of diphenylhydantoin.

B. Mirkin, 1971, American journal of obstetrics and gynecology.

Diphenylhydantoin: placental transport, fetal localization, neonatal metabolism, and possible teratogenic effects.

B. Mirkin, 1971, The Journal of pediatrics.

Down-regulation of growth factor-stimulated MAP kinase signaling in cytotoxic drug-resistant human neuroblastoma cells.

B. Mirkin, R. Mattingly, M. Milstein, 2001, Cellular signalling.

Effect of phenobarbital on hyperbilirubinemia, bile acid metabolism, and microsomal enzyme activity in chronic intrahepatic cholestasis of childhood.

B. Mirkin, H. Sharp, 1972, The Journal of pediatrics.

Resistance of proteinuric rats to furosemide: urinary drug protein binding as a determinant of drug effect.

B. Mirkin, T. Green, 1980, Life sciences.

Furosemide disposition in normal and proteinuric rats: urinary drug-protein binding as a determinant of drug excretion.

B. Mirkin, T. Green, 1981, The Journal of pharmacology and experimental therapeutics.

Clinical pharmacology of antihypertensive drugs in children.

A. Sinaiko, B. Mirkin, 1978, Pediatric clinics of North America.

Control of multidrug resistance gene mdr1 and cancer resistance to chemotherapy by the longevity gene sirt1.

A. Rebbaa, B. Mirkin, Xin Zheng, 2005, Cancer research.

Elimination kinetics of furosemide in perilymph and serum of the chinchilla. Neuropharmacologic correlates.

B. Mirkin, S. Juhn, T. Morizono, 1979, Acta oto-laryngologica.

Disposition and pharmacodynamics of diuretics and antihypertensive agents in renal disease

B. Mirkin, T. Green, R. O'dea, 2004, European Journal of Clinical Pharmacology.

Multiple mucosal neuromas, pheochromocytoma, medullary carcinoma of the thyroid and marfanoid body build with muscle wasting

R. Gorlin, B. Mirkin, 1972, Zeitschrift für Kinderheilkunde.

Chromogranins and Neurotransmitter Retention During Development of the Adrenergic Neuron

B. Mirkin, 1974 .

FACTORS INFLUENCING THE UPTAKE OF NORADRENALINE BY SUBCELLULAR PARTICLES IN HOMOGENATES OF RAT BRAIN.

N. J. Giarman, B. Mirkin, D. X. Freedman, 1964, Biochemical pharmacology.

The effect of synaptic blocking agents on reserpine-induced alterations in adrenal medullary and urinary catecholamine levels.

B. Mirkin, 1961, The Journal of pharmacology and experimental therapeutics.

THE SUBCELLULAR LOCALIZATION OF TRITIUM AFTER INCUBATION OF HOMOGENATES OF RAT BRAIN WITH 3H-NOREPINEPHRINE.

C. N. Gillis, B. Mirkin, C. Gillis, 1963, Biochemical pharmacology.

Uptake of noradrenaline by subcellular particles in homogenates of rat brain

N. J. Giarman, B. Mirkin, D. X. Freedman, 1963 .

A pharmacological and chemical study of humoral mediators in the sympathetic nervous system.

B. Mirkin, D. Bonnycastle, 1954, The American journal of physiology.

Catechol Amine Depletion in the Rat's Denervated Adrenal Gland following Chronic Administration of Reserpine

B. Mirkin, 1958, Nature.

Increased inosine-5'-phosphate dehydrogenase gene expression in solid tumor tissues and tumor cell lines.

F. Collart, B. Mirkin, E. Huberman, 1992, Cancer research.

Inhibitory effect of adenosine dialdehyde on in situ murine neuroblastoma growth.

B. Mirkin, B. Bostrom, H. P. Hogenkamp, 1988, Cancer research.

Cytotoxic action of adenosine nucleoside and dialdehyde analogues on murine neuroblastoma in tissue culture: structure-activity relationships.

B. Mirkin, R. O'dea, H. P. Hogenkamp, 1987, Cancer research.

Ion-pair extraction and high-speed liquid chromatography of cephalothin and deacetylcephalothin in human serum and urine.

B. Mirkin, M. W. Anders, M. Cooper, 1973, Drug metabolism and disposition: the biological fate of chemicals.

Determinants of drug disposition and effect in the fetus.

B. Mirkin, T. Green, R. O'dea, 1979, Annual review of pharmacology and toxicology.

Perinatal Pharmacology: Placental Transfer, Fetal Localization, and Neonatal Disposition of Drugs

B. Mirkin, 1975, Anesthesiology.

MDR1 Hypermethylation contributes to the progression of neuroblastoma

B. Mirkin, Y. Qiu, R. S. Dwivedi, 2007, Molecular and Cellular Biochemistry.

Biological characterization of the C-1300 murine neuroblastoma: an in vivo neural crest tumor model.

B. Mirkin, R. O'dea, G. Pons, 1982, Cancer research.

Expression of bisecting GlcNAc in pediatric brain tumors and its association with tumor cell response to vinblastine.

A. Rebbaa, B. Mirkin, E. Bremer, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Synthesis and In vitro activity of ROMP-based polymer nanoparticles.

S. Nguyen, B. Mirkin, D. Smith, 2009, Journal of materials chemistry.

Identification of midkine as a mediator for intercellular transfer of drug resistance

A. Rebbaa, B. Mirkin, Xin Zheng, 2005, Oncogene.

Pyrimidine base degradation in cultured murine C-1300 neuroblastoma cells and in situ tumors.

M. Tuchman, B. Mirkin, R. O'dea, 1988, The Journal of clinical investigation.

Urinary steroid levels in newborn infants with intrauterine growth retardation.

J. Reynolds, B. Mirkin, 1973, The Journal of clinical endocrinology and metabolism.

Metabolic disposition of cephalothin and deacetylcephalothin in children and adults: Comparison of high‐performance liquid chromatographic and microbial assay procedures

B. Mirkin, M. W. Anders, M. Cooper, 1977, Clinical pharmacology and therapeutics.

Molecular Genetics of Obesity Syndrome: Role of DNA Methylation

B. Mirkin, A. Sahai, R. S. Dwivedi, 2007 .

Report of the task force on blood pressure control in children.

E. Lieberman, R. Lauer, B. Mirkin, 1977, Pediatrics.

Nerve growth factor regulates neuroectodermal tumor cell responses to mitogenic growth factors

B. Mirkin, R. Castellon, 2003, Journal of neuroscience research.

Caspase inhibition switches doxorubicin-induced apoptosis to senescence

A. Rebbaa, B. Mirkin, Xin Zheng, 2003, Oncogene.

Treatment of neonatal hypertension with captopril.

A. Sinaiko, B. Mirkin, R. O'dea, 1988, The Journal of pediatrics.

Renal autotransplantation in the treatment of bilateral renal artery stenosis: relief of hypertension in an 8-year-old boy.

A. Michael, A. Sinaiko, J. Najarian, 1973, The Journal of pediatrics.

Role of DNA Methylation in Cancer and Chemotherapy

B. Mirkin, Y. Qiu, R. S. Dwivedi, 2004 .

Perinatal pharmacology and therapeutics

B. Mirkin, M. Juchau, 1976 .

Tobramycin Serum Level Monitoring in Young Patients with Normal Renal Function

A. Sinaiko, B. Mirkin, P. Peterson, 1984, Clinical pharmacokinetics.

Maternal and fetal distribution of drugs in pregnancy

B. Mirkin, 1973, Clinical pharmacology and therapeutics.

Cellular conditioning with trichostatin A enhances the anti‐stress response through up‐regulation of HDAC4 and down‐regulation of the IGF/Akt pathway

S. Mousa, A. Rebbaa, B. Mirkin, 2008, Aging cell.

Senescence-initiated Reversal of Drug Resistance

A. Rebbaa, B. Mirkin, Xin Zheng, 2004, Cancer Research.

Drug disposition and therapy in the developing human being.

B. Mirkin, 1976, Pediatric annals.

Circulatory and humoral responses of sympathectomized fetal sheep to hypoxemia.

B. Mirkin, L. Keil, H. Iwamoto, 1983, The American journal of physiology.

Ontogenesis of the adrenergic nervous system: functional and pharmacologic implications.

B. Mirkin, 1972, Federation proceedings.

Relation between plasma and red-cell electrolyte concentrations and digoxin levels in children.

J. Lock, B. Mirkin, S. Singh, 1978, The New England journal of medicine.

ADRENAL CORTICAL FUNCTION IN ABNORMAL NEWBORN INFANTS

J. Reynolds, B. Mirkin, M. R. Turnipseed, 1976 .

S-adenosylmethionine synthetase is overexpressed in murine neuroblastoma cells resistant to nucleoside analogue inhibitors of S-adenosylhomocysteine hydrolase: a novel mechanism of drug resistance.

B. Mirkin, R. S. Dwivedi, L. J. Wang, 1999, Cancer research.

Role of the proteolytic hierarchy between cathepsin L, cathepsin D and caspase-3 in regulation of cellular susceptibility to apoptosis and autophagy.

S. Mousa, A. Rebbaa, B. Mirkin, 2008, Biochimica et biophysica acta.

Resistance to inhibitors of S-adenosyl-L-homocysteine hydrolase in C1300 murine neuroblastoma tumor cells is associated with increased methionine adenosyltransferase activity.

B. Mirkin, S. Clark, M. Hamre, 1995, Oncology Research.

Suppression of C-1300 murine neuroblastoma cell proliferation in tissue culture and tumor growth in vivo by (Z)5'-fluoro-4',5'-didehydro-5'-deoxyadenosine (MDL 28,842), an irreversible inhibitor of S-adenosyl-L-homocysteine hydrolase.

B. Mirkin, T. Bowlin, C. Zhang, 1993, Oncology Research.

Drug interactions

B. Mirkin, Francis Wright, 1971, Neurology.

Placental transfer and tissue localization of digoxin in the pregnant rat.

B. Mirkin, S. Singh, 1978, Toxicology and applied pharmacology.

Ontogenesis of the Renin‐Angiotensin System in Spontaneously Hypertensive and Normal Wistar Rats

B. Mirkin, 1974, Circulation research.

Antihypertensive drug therapy with captopril in children and adolescents.

A. Sinaiko, B. Mirkin, C. Kashtan, 1986, Clinical and experimental hypertension. Part A, Theory and practice.

Determinants of the diuretic response to furosemide in infants with congestive heart failure

B. Mirkin, T. Green, 1982, Pediatric Cardiology.

Inhibition of human neuroblastoma cell proliferation and EGF receptor phosphorylation by gangliosides GM1, GM3, GD1A and GT1B

B. Mirkin, S. Clark, C. Zhang, 2002, Cell proliferation.

Distribution and metabolism of diphenyl-hydantoin- 14 C in fetal and maternal tissues of the pregnant mouse.

B. Mirkin, W. Waddell, 1972, Biochemical pharmacology.

Management of severe childhood hypertension with minoxidil: a controlled clinical study.

A. Sinaiko, B. Mirkin, 1977, The Journal of pediatrics.

Elevation of cerebrospinal fluid catecholamine metabolites in patients with intracranial tumors of neuroectodermal origin.

B. Mirkin, B. Bostrom, 1987, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Pharmacologic determinants of ototoxicity of furosemide in the chinchilla.

B. Mirkin, S. Juhn, T. Morizono, 1981, The Journal of pharmacology and experimental therapeutics.

Inhibitor of S-Adenosylhomocysteine Hydrolase, Suppresses Proliferation of Cultured Keratinocytes and Squamous Carcinoma Cell Lines1

B. Mirkin, S. L. Arnsmeier, S. Clark, 1993 .

Effects of chemical sympathectomy in neonatal and adult mice on C-1300 neuroblastoma tumor growth and catecholamine content.

B. Mirkin, D. Fink, 1987, Cancer research.

Influence of host age and tumor load on the growth and catecholamine content of C-1300 murine neuroblastoma in situ.

B. Mirkin, P. Horn, D. Fink, 1990, Cancer letters.

Modulation of in situ murine neuroblastoma tumor growth by the adrenergic nervous system: differential response of clonal cell lines to chemical sympathectomy.

B. Mirkin, P. Horn, 1990, Life sciences.

Lack of effect of the opioid antagonist, naltrexone, on the in situ growth of C-1300, N1E-115 and NS206 murine neuroblastoma tumor cell lines.

B. Mirkin, P. Horn, 1989, Life sciences.

Clinical pharmacology and therapeutics--a pediatric perspective

B. Mirkin, 1978 .

A rapid micromethod for the high-performance liquid chromatographic determination of theophylline in human serum.

B. Mirkin, M. W. Anders, M. Cooper, 1977, Journal of chromatography.

Effect of calcium, sodium and isoproterenol on renin secretion from disaggregated rat renal cortical cells.

B. Mirkin, J. A. Hansen, R. O'dea, 1984, Research communications in chemical pathology and pharmacology.

Kinetics of digoxin absorption and relation of serum levels to cardiac arrhythmias in children

B. Mirkin, R. Larese, 1974, Clinical pharmacology and therapeutics.

ONTOGENESIS OF RENIN-ANGIOTENSIN SYSTEM 695 and the 21-day-old neonatal spontaneously hypertensive

A. Sinaiko, B. Mirkin, 2005 .

Influence of salt depletion and hydralazine-induced vasodilatation on accuracy of selective renal vein sampling in patients with essential hypertension and renal artery stenosis.

A. Sinaiko, B. Mirkin, 1982, American Journal of Nephrology.

Antihypertensive effect and elimination kinetics of captopril in hypertensive children with renal disease.

A. Sinaiko, B. Mirkin, T. Green, 1983, The Journal of pediatrics.

HYDROCHLOROTHIAZIDE (HCT) THERAPY IN HYPERTENSIVE (HT) AND RENAL INSUFFICIENT (RI) CHILDREN: ELIMINATION KINETICS AND METABOLIC EFFECTS

A. Sinaiko, B. Mirkin, M. Cooper, 1977, Pediatric Research.

Protein carboxyl-O-methyltransferase activity in cultured C-1300 neuroblastoma cells.

B. Mirkin, J. A. Hansen, R. O'dea, 1983, Biochemical pharmacology.

Characterization of protein carboxyl-O-methyltransferase in the spontaneous in vivo murine C-1300 neuroblastoma.

B. Mirkin, J. A. Hansen, R. O'dea, 1982, Cancer research.

A method for the bedside application of first-order pharmacokinetics in therapeutic management.

B. Mirkin, T. Green, 1980, Therapeutic drug monitoring.

1127 SODIUM BENZOATE IN THE TREATMENT OF HYPERAMMONEMIA IN NEWBORNS

B. Mirkin, T. Green, 1981, Pediatric Research.

Biological maturation and beta-adrenergic effectors: pre- and postnatal development of the adenylate cyclase system in the rabbit heart.

B. Mirkin, J. Sheppard, W. Schumacher, 1982, The Journal of pharmacology and experimental therapeutics.

SI units and pediatric therapeutics.

R. Roberts, B. Rumack, B. Mirkin, 1987, The Journal of pediatrics.

Metabolie disposition of methyldopa in hypertensive and renal‐insufficient children

B. Mirkin, R. O'dea, 1980, Clinical pharmacology and therapeutics.

Clinical Response of Hypertensive Children to Long‐Term Minoxidil Therapy

A. Sinaiko, B. Mirkin, R. O'dea, 1980, Journal of cardiovascular pharmacology.

Furosemide (F) disposition in normal and nephrotic rats: Urinary drug-protein binding as a determinant of drug excretion

B. Mirkin, T. Green, 1980 .

Mechanisms of resistance to furosemide (F) diuresis in children with edema

B. Mirkin, T. Green, 1979 .

Adrenal cortical function in abnormal newborn infants.

J. Reynolds, B. Mirkin, M. R. Turnipseed, 1975, Journal of Steroid Biochemistry.

Doxorubicin-induced apoptosis in caspase-8-deficient neuroblastoma cells is mediated through direct action on mitochondria

M. Emran, A. Rebbaa, B. Mirkin, 2001, Cancer Chemotherapy and Pharmacology.

DNA (cytosine) methyltransferase overexpression is associated with acquired drug resistance of murine neuroblastoma cells.

B. Mirkin, C. Wang, R. S. Dwivedi, 2001, International journal of oncology.

Management minoxidil: A of severe childhood hypertension controlled clinical study with

A. Sinaiko, B. Mirkin, 1977 .

Determination of methyldopa and metabolites in human serum by high-performance liquid chromatography with electrochemical detection.

B. Mirkin, M. Cooper, R. O'dea, 1979, Journal of chromatography.

Fetal Chemical Sympathectomy: Circulatory and Hormonal Responses to Hypoxemia

B. Mirkin, L. Keil, H. Iwamoto, 1988 .