N. Patel

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Insulin Regulates Alternative Splicing of Protein Kinase C βII through a Phosphatidylinositol 3-Kinase-dependent Pathway Involving the Nuclear Serine/Arginine-rich Splicing Factor, SRp40, in Skeletal Muscle Cells*

J. Wyatt, N. Dean, N. Patel, 2001, The Journal of Biological Chemistry.

Circulating long noncoding RNA GAS5 levels are correlated to prevalence of type 2 diabetes mellitus

N. Patel, L. Deland, S. Mastorides, 2015, BBA clinical.

Direct Actions of Granulocyte-Colony Stimulating Factor on Human Neuronal and Monocytic Cell Lines

N. Patel, J. Sanchez-Ramos, V. Sava, 2013 .

Developmentally spliced PKCbetaII provides a possible link between mTORC2 and Akt kinase to regulate 3T3-L1 adipocyte insulin-stimulated glucose transport.

N. Patel, D. Cooper, G. Carter, 2009, Biochemical and biophysical research communications.

Ceramide-Activated Protein Phosphatase (CAPP) involvement in insulin resistance via Akt, SRp40, and RNA splicing in L6 skeletal muscle cells

K. Jiang, N. Patel, J. Watson, 2009 .

Ceramide-activated protein phosphatase involvement in insulin resistance via Akt, serine/arginine-rich protein 40, and ribonucleic acid splicing in L6 skeletal muscle cells.

K. Jiang, N. Patel, C. Chalfant, 2007, Endocrinology.

Induction of beige‐like adipocyte markers and functions in 3T3‐L1 cells by Clk1 and PKCβII inhibitory molecules

N. Patel, G. Carter, X. Kong, 2022, Journal of cellular and molecular medicine.

Ectopic Expression of Protein Kinase CβII, -δ, and -ϵ, but Not -βI or -ζ, Provide for Insulin Stimulation of Glucose Uptake in NIH-3T3 Cells

H. Mischak, N. Patel, C. Chalfant, 1999 .

Management of nonalcoholic fatty liver disease and the role of bariatric surgery: a brief review for surgeons.

N. Patel, M. Murr, J. Gonzalvo, 2020, Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery.

Adipose-derived stem cells from lean and obese humans show depot specific differences in their stem cell markers, exosome contents and senescence: role of protein kinase C delta (PKCδ) in adipose stem cell niche.

N. Patel, D. Cooper, G. Carter, 2016, Stem cell investigation.

Protein kinase C delta (PKCδ) splice variant modulates senescence via hTERT in adipose-derived stem cells.

N. Patel, D. Cooper, G. Carter, 2014, Stem cell investigation.

Dysregulated Alternative Splicing Pattern of PKCδ during Differentiation of Human Preadipocytes Represents Distinct Differences between Lean and Obese Adipocytes

N. Patel, D. Cooper, A. Mathur, 2013, ISRN obesity.

The effects of interaction between morphine and interleukin-1 on the immune response.

N. Patel, S. L. Chang, M. Fiala, 1998, Advances in experimental medicine and biology.

A specific small-molecule inhibitor of protein kinase CδI activity improves metabolic dysfunction in human adipocytes from obese individuals

W. Guida, N. Patel, R. Fratti, 2019, The Journal of Biological Chemistry.

Insulin rapidly upregulates protein kinase Cdelta gene expression in skeletal muscle.

N. Patel, D. Cooper, A. Bak, 2006, Cellular signalling.

Dexamethasone affects cytokine-mediated adhesion of HL-60 human promyelocytic leukemia cells to cultured dermal microvascular endothelial cells.

N. Patel, M. Stins, J. A. Patel, 2001, Clinical immunology.

Comparison of Markers and Functional Attributes of Human Adipose-Derived Stem Cells and Dedifferentiated Adipocyte Cells from Subcutaneous Fat of an Obese Diabetic Donor.

P. Bickford, N. Patel, J. Watson, 2014, Advances in wound care.

Intravenous Transplants of Human Adipose-Derived Stem Cell Protect the Brain from Traumatic Brain Injury-Induced Neurodegeneration and Motor and Cognitive Impairments: Cell Graft Biodistribution and Soluble Factors in Young and Aged Rats

P. Bickford, N. Patel, N. Tajiri, 2014, The Journal of Neuroscience.

Human Adipose-Derived Stem Cell Conditioned Media and Exosomes Containing MALAT1 Promote Human Dermal Fibroblast Migration and Ischemic Wound Healing

N. Patel, D. Cooper, L. Gould, 2018, Advances in wound care.

Acute hyperglycemia regulates transcription and posttranscriptional stability of PKCβII mRNA in vascular smooth muscle cells

N. Patel, C. Chalfant, J. Watson, 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Long noncoding RNA MALAT1 in exosomes drives regenerative function and modulates inflammation-linked networks following traumatic brain injury

P. Bickford, N. Patel, N. Tajiri, 2018, Journal of Neuroinflammation.

Small molecule targeting long noncoding RNA GAS5 administered intranasally improves neuronal insulin signaling and decreases neuroinflammation in an aged mouse model

P. Bickford, N. Patel, S. Hill, 2023, Scientific Reports.

Stabilization of lncRNA GAS5 by a Small Molecule and Its Implications in Diabetic Adipocytes.

N. Patel, Jianfeng Cai, Rekha S. Patel, 2019, Cell chemical biology.

MALAT1 in Human Adipose Stem Cells Modulates Survival and Alternative Splicing of PKC&dgr;II in HT22 Cells

P. Bickford, N. Patel, D. Cooper, 2016, Endocrinology.

Long Non-Coding RNA NEAT1 Associates with SRp40 to Temporally Regulate PPARγ2 Splicing during Adipogenesis in 3T3-L1 Cells

Pengfei Li, N. Patel, J. Watson, 2014, Genes.

Clk/STY (cdc2-Like Kinase 1) and Akt Regulate Alternative Splicing and Adipogenesis in 3T3-L1 Pre-Adipocytes

Pengfei Li, N. Patel, J. Watson, 2013, PloS one.

Interleukin-1 induces the expression of mu opioid receptors in endothelial cells.

N. Patel, S. L. Chang, M. Fiala, 1998, Immunopharmacology.

Insulin Promotes Neuronal Survival via the Alternatively Spliced Protein Kinase CδII Isoform*

P. Bickford, N. Patel, J. Watson, 2012, The Journal of Biological Chemistry.

Intranasal delivery of exosomes from human adipose derived stem cells at forty-eight hours post injury reduces motor and cognitive impairments following traumatic brain injury

P. Bickford, N. Patel, C. Hudson, 2021, Neurochemistry International.

Protein Kinase C δ (PKCδ) Splice Variants Modulate Apoptosis Pathway in 3T3L1 Cells during Adipogenesis

N. Patel, D. Cooper, G. Carter, 2013, The Journal of Biological Chemistry.

Vitamin A Metabolite, All-trans-retinoic Acid, Mediates Alternative Splicing of Protein Kinase C δVIII (PKCδVIII) Isoform via Splicing Factor SC35*

F. Vale, N. Patel, J. Watson, 2010, The Journal of Biological Chemistry.

Insulin regulates protein kinase CbetaII alternative splicing in multiple target tissues: development of a hormonally responsive heterologous minigene.

N. Patel, C. Chalfant, J. Watson, 2004, Molecular endocrinology.

The Protein Kinase C βII Exon Confers mRNA Instability in the Presence of High Glucose Concentrations*

J. Wyatt, D. Chappell, N. Dean, 2003, The Journal of Biological Chemistry.

Molecular and Genetic Studies Imply Akt-mediated Signaling Promotes Protein Kinase CβII Alternative Splicing via Phosphorylation of Serine/Arginine-rich Splicing Factor SRp40*

J. Cheng, M. Birnbaum, D. Chappell, 2005, Journal of Biological Chemistry.

Long non‐coding RNA NEAT 1 & 2 regulates phosphorylation of SR proteins and PKCβII splicing during 3T3 L1 adipogenesis

N. Patel, J. Watson, G. Carter, 2012 .

Akt2 regulation of Cdc2-like kinases (Clk/Sty), serine/arginine-rich (SR) protein phosphorylation, and insulin-induced alternative splicing of PKCbetaII messenger ribonucleic acid.

M. Hagiwara, K. Jiang, N. Patel, 2009, Endocrinology.

Multilevel Regulation of Protein Kinase CδI Alternative Splicing by Lithium Chloride

N. Patel, Rekha S. Patel, C. Thawani, 2020, Molecular and Cellular Biology.

Phosphoinositide 3-kinase mediates protein kinase C beta II mRNA destabilization in rat A10 smooth muscle cell cultures exposed to high glucose.

D. Chappell, N. Patel, J. Watson, 2002, Archives of biochemistry and biophysics.

The Roles of Protein Kinase C I and II in Vascular Smooth Muscle Cell Proliferation

N. Patel, C. Chalfant, J. Watson, 1998 .

Acute glucose-induced downregulation of PKC-βII accelerates cultured VSMC proliferation

N. Patel, C. Chalfant, J. Watson, 2000 .

A shift from normal to high glucose levels stimulates cell proliferation in drug sensitive MCF‐7 human breast cancer cells but not in multidrug resistant MCF‐7/ADR cells which overproduce PKC‐βII

N. Patel, D. Cooper, R. Sridhar, 1999, International journal of cancer.

The Involvement of Protein Kinase C-βII in Glucose-Induced Rat Vascular Smooth Muscle Cell Proliferation

N. Patel, D. Cooper, Mayumi Yamamoto, 1998 .

Functional involvement of protein kinase C-βII and its substrate, myristoylated alanine-rich C-kinase substrate (MARCKS), in insulin-stimulated glucose transport in L6 rat skeletal muscle cells

K. Jiang, D. Chappell, N. Patel, 2009, Diabetologia.

Changing Signals to the Spliceosome

N. Patel, D. Cooper, 2012 .

OR01-6 LncRNA GAS5 Directed Therapeutic Increases Insulin Receptor Expression in Adipocytes

N. Patel, Jianfeng Cai, Yan Shi, 2019, Journal of the Endocrine Society.

Ectopic expression of protein kinase CbetaII, -delta, and -epsilon, but not -betaI or -zeta, provide for insulin stimulation of glucose uptake in NIH-3T3 cells.

H. Mischak, N. Patel, C. Chalfant, 1999, Archives of Biochemistry and Biophysics.

Transformer 2β homolog (Drosophila) (TRA2B) Regulates Protein Kinase C δI (PKCδI) Splice Variant Expression during 3T3L1 Preadipocyte Cell Cycle*

N. Patel, D. Cooper, G. Carter, 2014, The Journal of Biological Chemistry.

Protein Kinase C (cid:1) (PKC (cid:1) ) Splice Variants Modulate Apoptosis Pathway in 3T3L1 Cells during Adipogenesis OF PKC (cid:1) II INHIBITOR

N. Patel, D. Cooper, G. Carter, 2013 .

Long noncoding RNA MALAT1 in exosomes drives regenerative function and modulates inflammation-linked networks following traumatic brain injury

P. Bickford, N. Patel, N. Tajiri, 2018, Journal of Neuroinflammation.

Adult Bone Marrow Stromal Cells Differentiate into Neural Cells in Vitro

W. Janssen, F. Cardozo-Pelaez, P. Sanberg, 2000, Experimental Neurology.

Identification of Sortilin Alternatively Spliced Variants in Mouse 3T3L1 Adipocytes

N. Patel, Rekha S. Patel, Robert P. Sparks, 2021, International journal of molecular sciences.

Akt2 regulation of Cdc2-like kinases (Clk/Sty), serine/arginine-rich (SR) protein phosphorylation, and insulin-induced alternative splicing of PKCbetaII messenger ribonucleic acid.

M. Hagiwara, K. Jiang, N. Patel, 2009, Endocrinology.

Insulin regulates protein kinase CbetaII alternative splicing in multiple target tissues: development of a hormonally responsive heterologous minigene.

N. Patel, C. Chalfant, J. Watson, 2004, Molecular Endocrinology.

Insulin regulates protein kinase CbetaII expression through enhanced exon inclusion in L6 skeletal muscle cells. A novel mechanism of insulin- and insulin-like growth factor-i-induced 5' splice site selection.

L. Obeid, N. Patel, C. Chalfant, 1998, Journal of Biological Chemistry.

PKCdelta alternatively spliced isoforms modulate cellular apoptosis in retinoic acid-induced differentiation of human NT2 cells and mouse embryonic stem cells.

N. Patel, D. Cooper, Shijie Song, 2006, Gene Expression.

PKCδ Alternatively Spliced Isoforms Modulate Cellular Apoptosis in Retinoic Acid-Induced Differentiation of Human NT2 Cells and Mouse Embryonic Stem Cells

N. Patel, D. Cooper, Shijie Song, 2006 .

Identification of a novel antiapoptotic human protein kinase C delta isoform, PKCdeltaVIII in NT2 cells.

K. Jiang, N. Patel, J. Watson, 2008, Biochemistry.

Insulin improves memory and cognition via protein kinase c delta ([delta])

N. Patel, D. Cooper, André H Apostolatos, 2012 .