J. Watson

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Insulin Regulates Alternative Splicing of Protein Kinase C βII through a Phosphatidylinositol 3-Kinase-dependent Pathway Involving the Nuclear Serine/Arginine-rich Splicing Factor, SRp40, in Skeletal Muscle Cells*

J. Wyatt, N. Dean, N. Patel, 2001, The Journal of Biological Chemistry.

Decreased expression of protein kinase-C alpha, beta, and epsilon in soleus muscle of Zucker obese (fa/fa) rats.

J. Watson, D. Cooper, M. Dao, 1993, Endocrinology.

Sulfonylurea-Stimulated Glucose Transport Association With Diacylglycerollike Activation of Protein Kinase C in BC3H1 Myocytes

R. Farese, J. Watson, D. Cooper, 1990, Diabetes.

Ceramide-Activated Protein Phosphatase (CAPP) involvement in insulin resistance via Akt, SRp40, and RNA splicing in L6 skeletal muscle cells

K. Jiang, N. Patel, J. Watson, 2009 .

Ceramide-activated protein phosphatase involvement in insulin resistance via Akt, serine/arginine-rich protein 40, and ribonucleic acid splicing in L6 skeletal muscle cells.

K. Jiang, N. Patel, C. Chalfant, 2007, Endocrinology.

Ectopic Expression of Protein Kinase CβII, -δ, and -ϵ, but Not -βI or -ζ, Provide for Insulin Stimulation of Glucose Uptake in NIH-3T3 Cells

H. Mischak, N. Patel, C. Chalfant, 1999 .

Protein kinase C activation patterns are determined by methodological variations. Studies of insulin action in BC3H-1 myocytes and rat adipose tissue.

R. Farese, J. Watson, D. Cooper, 1990, Biochimica et biophysica acta.

Mechanisms for cardiac depression induced by phorbol myristate acetate in working rat hearts

J. Watson, M. Karmazyn, M. Moffat, 1990, British journal of pharmacology.

Antisense DNA downregulates protein kinase C isozymes (beta and alpha) and insulin-stimulated 2-deoxyglucose uptake in rat adipocytes.

E. Wickstrom, R. Farese, J. Watson, 1991, Antisense research and development.

Chronic effects of glucose on insulin signaling in A-10 vascular smooth muscle cells.

J. Watson, D. Cooper, A. Khalakdina, 1993, Archives of biochemistry and biophysics.

Comparison of Markers and Functional Attributes of Human Adipose-Derived Stem Cells and Dedifferentiated Adipocyte Cells from Subcutaneous Fat of an Obese Diabetic Donor.

P. Bickford, N. Patel, J. Watson, 2014, Advances in wound care.

Acute hyperglycemia regulates transcription and posttranscriptional stability of PKCβII mRNA in vascular smooth muscle cells

N. Patel, C. Chalfant, J. Watson, 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Glucose‐induced synthesis of diacylglycerol de novo is associated with translocation (activation) of protein kinase C in rat adipocytes

R. Farese, J. Watson, D. Cooper, 1989, FEBS letters.

Long Non-Coding RNA NEAT1 Associates with SRp40 to Temporally Regulate PPARγ2 Splicing during Adipogenesis in 3T3-L1 Cells

Pengfei Li, N. Patel, J. Watson, 2014, Genes.

Clk/STY (cdc2-Like Kinase 1) and Akt Regulate Alternative Splicing and Adipogenesis in 3T3-L1 Pre-Adipocytes

Pengfei Li, N. Patel, J. Watson, 2013, PloS one.

Insulin Promotes Neuronal Survival via the Alternatively Spliced Protein Kinase CδII Isoform*

P. Bickford, N. Patel, J. Watson, 2012, The Journal of Biological Chemistry.

Vitamin A Metabolite, All-trans-retinoic Acid, Mediates Alternative Splicing of Protein Kinase C δVIII (PKCδVIII) Isoform via Splicing Factor SC35*

F. Vale, N. Patel, J. Watson, 2010, The Journal of Biological Chemistry.

Insulin regulates protein kinase CbetaII alternative splicing in multiple target tissues: development of a hormonally responsive heterologous minigene.

N. Patel, C. Chalfant, J. Watson, 2004, Molecular endocrinology.

The Protein Kinase C βII Exon Confers mRNA Instability in the Presence of High Glucose Concentrations*

J. Wyatt, D. Chappell, N. Dean, 2003, The Journal of Biological Chemistry.

Molecular and Genetic Studies Imply Akt-mediated Signaling Promotes Protein Kinase CβII Alternative Splicing via Phosphorylation of Serine/Arginine-rich Splicing Factor SRp40*

J. Cheng, M. Birnbaum, D. Chappell, 2005, Journal of Biological Chemistry.

Long non‐coding RNA NEAT 1 & 2 regulates phosphorylation of SR proteins and PKCβII splicing during 3T3 L1 adipogenesis

N. Patel, J. Watson, G. Carter, 2012 .

Akt2 regulation of Cdc2-like kinases (Clk/Sty), serine/arginine-rich (SR) protein phosphorylation, and insulin-induced alternative splicing of PKCbetaII messenger ribonucleic acid.

M. Hagiwara, K. Jiang, N. Patel, 2009, Endocrinology.

Regulation of Alternative Splicing of Protein Kinase Cβ by Insulin (*)

Robert V Farese, B. C. Winkler, H. Mischak, 1995, The Journal of Biological Chemistry.

Regulation of alternative splicing of protein kinase C beta by insulin.

B. C. Winkler, H. Mischak, R. Farese, 1995, The Journal of biological chemistry.

Phosphoinositide 3-kinase mediates protein kinase C beta II mRNA destabilization in rat A10 smooth muscle cell cultures exposed to high glucose.

D. Chappell, N. Patel, J. Watson, 2002, Archives of biochemistry and biophysics.

A carboxy-terminal deletion mutant of protein kinase C beta II inhibits insulin-stimulated 2-deoxyglucose uptake in L6 rat skeletal muscle cells.

C. Chalfant, J. Watson, D. Cooper, 1996, Molecular endocrinology.

Direct evidence for protein kinase C involvement in insulin-stimulated hexose uptake.

R. Farese, J. Watson, D. Cooper, 1992, Biochemical and biophysical research communications.

The Roles of Protein Kinase C I and II in Vascular Smooth Muscle Cell Proliferation

N. Patel, C. Chalfant, J. Watson, 1998 .

Retention of specific protein kinase C isozymes following chronic phorbol ester treatment in BC3H-1 myocytes.

R. Farese, J. Watson, D. Cooper, 1989, Biochemical and biophysical research communications.

Concentration-dependent effects of protein kinase C-activating and -nonactivating phorbol esters on myocardial contractility, coronary resistance, energy metabolism, prostacyclin synthesis, and ultrastructure in isolated rat hearts. Effects of amiloride.

J. Watson, M. Karmazyn, 1991, Circulation research.

Acute glucose-induced downregulation of PKC-βII accelerates cultured VSMC proliferation

N. Patel, C. Chalfant, J. Watson, 2000 .

Functional involvement of protein kinase C-βII and its substrate, myristoylated alanine-rich C-kinase substrate (MARCKS), in insulin-stimulated glucose transport in L6 rat skeletal muscle cells

K. Jiang, D. Chappell, N. Patel, 2009, Diabetologia.

Protein Kinase Cθ Expression Is Increased upon Differentiation of Human Skeletal Muscle Cells: Dysregulation in Type 2 Diabetic Patients and a Possible Role for Protein Kinase Cθ in Insulin-Stimulated Glycogen Synthase Activity.

R. Henry, C. Chalfant, J. Watson, 2000, Endocrinology.

Ectopic expression of protein kinase CbetaII, -delta, and -epsilon, but not -betaI or -zeta, provide for insulin stimulation of glucose uptake in NIH-3T3 cells.

H. Mischak, N. Patel, C. Chalfant, 1999, Archives of Biochemistry and Biophysics.

Effects of insulin on diacylglycerol/protein kinase-C signalling and glucose transport in rat skeletal muscles in vivo and in vitro.

R. Farese, J. Watson, D. Cooper, 1992, Endocrinology.

Deletion Mutant of Protein Kinase Cpll Inhibits Insulin-Stimulated 2- Deoxyglucose Uptake in L6 Rat Skeletal Muscle Cells

C. Chalfant, J. Watson, D. Cooper, 1996 .

Akt2 regulation of Cdc2-like kinases (Clk/Sty), serine/arginine-rich (SR) protein phosphorylation, and insulin-induced alternative splicing of PKCbetaII messenger ribonucleic acid.

M. Hagiwara, K. Jiang, N. Patel, 2009, Endocrinology.

Insulin regulates protein kinase CbetaII alternative splicing in multiple target tissues: development of a hormonally responsive heterologous minigene.

N. Patel, C. Chalfant, J. Watson, 2004, Molecular Endocrinology.

Insulin regulates protein kinase CbetaII expression through enhanced exon inclusion in L6 skeletal muscle cells. A novel mechanism of insulin- and insulin-like growth factor-i-induced 5' splice site selection.

L. Obeid, N. Patel, C. Chalfant, 1998, Journal of Biological Chemistry.

Protein kinase Ctheta expression is increased upon differentiation of human skeletal muscle cells: dysregulation in type 2 diabetic patients and a possible role for protein kinase Ctheta in insulin-stimulated glycogen synthase activity.

R. Henry, C. Chalfant, J. Watson, 2000, Endocrinology.

Effects of insulin and phorbol esters on MARCKS (myristoylated alanine-rich C-kinase substrate) phosphorylation (and other parameters of protein kinase C activation) in rat adipocytes, rat soleus muscle and BC3H-1 myocytes.

H. Mischak, R. Farese, J. Watson, 1993, The Biochemical journal.

Identification of a novel antiapoptotic human protein kinase C delta isoform, PKCdeltaVIII in NT2 cells.

K. Jiang, N. Patel, J. Watson, 2008, Biochemistry.