N. Bishopric

发表

Reperfusion-Activated Akt Kinase Prevents Apoptosis in Transgenic Mouse Hearts Overexpressing Insulin-Like Growth Factor-1

K. Webster, P. Anversa, J. Kajstura, 2001, Circulation research.

A Large Candidate Gene Survey Identifies the KCNE1 D85N Polymorphism as a Possible Modulator of Drug-Induced Torsades de Pointes

Marylyn D. Ritchie, Thomas Meitinger, Dana C. Crawford, 2012, Circulation. Cardiovascular genetics.

Myocyte deficiency as a target in the treatment of cardiomyopathy

K. Webster, N. Bishopric, Lina A. Shehadeh, 2007 .

Genome-Wide Identification of Expression Quantitative Trait Loci (eQTLs) in Human Heart

C. D. dos Remedios, A. George, P. Moerland, 2014, PLoS ONE.

Reversible Connexin 43 Dephosphorylation During Hypoxia and Reoxygenation Is Linked to Cellular ATP Levels

K. Webster, N. Bishopric, G. Haywood, 2004, Circulation research.

The Lysine Acetyltransferases in Cardiovascular Disease

N. Bishopric, 2016 .

Bucindolol Displays Intrinsic Sympathomimetic Activity in Human Myocardium

N. Aiyar, K. Webster, N. Bishopric, 2002, Circulation.

Molecular mechanisms of apoptosis in the cardiac myocyte.

K. Webster, N. Bishopric, P. Andréka, 2001, Current opinion in pharmacology.

Regulation of Bnip3 death pathways by calcium, phosphorylation, and hypoxia-reoxygenation.

K. Webster, N. Bishopric, R. Graham, 2007, Antioxidants & redox signaling.

Activation of c-Jun N-terminal kinase promotes survival of cardiac myocytes after oxidative stress.

K. Webster, N. Bishopric, Lori A Kubasiak, 2002, The Biochemical journal.

Acidosis regulates the stability, hydrophobicity, and activity of the BH3-only protein Bnip3.

K. Webster, N. Bishopric, R. Graham, 2006, Antioxidants & redox signaling.

Erratum to: PI3K/mTOR inhibition can impair tumor invasion and metastasis in vivo despite a lack of antiproliferative action in vitro: implications for targeted therapy

C. Creighton, C. Milikowski, A. Minn, 2016, Breast Cancer Research and Treatment.

PI3K/mTOR inhibition can impair tumor invasion and metastasis in vivo despite a lack of antiproliferative action in vitro: implications for targeted therapy

C. Creighton, C. Milikowski, A. Minn, 2013, Breast Cancer Research and Treatment.

Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy

E. Petretto, F. Cambien, Y. Pinto, 2017, Genome Biology.

Cardioprotection in an in vitro model of hypoxic preconditioning.

K. Webster, D. J. Discher, N. Bishopric, 1995, Journal of molecular and cellular cardiology.

Molecular Regulation of the Endothelin-1 Gene by Hypoxia

K. Webster, D. J. Discher, K. Yamashita, 2001, The Journal of Biological Chemistry.

Hypoxia Regulates β-Enolase and Pyruvate Kinase-M Promoters by Modulating Sp1/Sp3 Binding to a Conserved GC Element*

K. Webster, C. Peterson, D. J. Discher, 1998, The Journal of Biological Chemistry.

Negative lusitropy and abnormal calcium handling in hypoxic cardiac myocytes exposed to the calcium-sensitizer EMD 53998.

K. Webster, D. J. Discher, N. Bishopric, 1993, Journal of molecular and cellular cardiology.

Review Article Gene and Cell Therapy for Heart Disease

K. Webster, N. Bishopric, R. Graham, 2002 .

Gene and Cell Therapy for Heart Disease

K. Webster, N. Bishopric, R. Graham, 2002, IUBMB life.

Adverse Cardiovascular Events in Cancer Trials: Missing in Action?

N. Bishopric, M. Lippman, 2020, Journal of the American College of Cardiology.

Redox stress and the contributions of BH3-only proteins to infarction.

K. Webster, N. Bishopric, R. Graham, 2006, Antioxidants & redox signaling.

Fusigenic liposome-mediated DNA transfer into cardiac myocytes.

Y. Kaneda, R. Morishita, K. Webster, 1996, Journal of molecular and cellular cardiology.

Quantitative Control of Adaptive Cardiac Hypertrophy by Acetyltransferase p300

K. Webster, N. Bishopric, Lina A. Shehadeh, 2008, Circulation.

Regulation of fos and jun immediate-early genes by redox or metabolic stress in cardiac myocytes.

K. Webster, D. J. Discher, N. Bishopric, 1994, Circulation research.

Induction and nuclear accumulation of fos and jun proto-oncogenes in hypoxic cardiac myocytes.

K. Webster, D. J. Discher, N. Bishopric, 1993, The Journal of biological chemistry.

PKC-alpha and TAK-1 are intermediates in the activation of c-Jun NH2-terminal kinase by hypoxia-reoxygenation.

K. Webster, N. Bishopric, C. Dougherty, 2007, American journal of physiology. Heart and circulatory physiology.

CALL FOR PAPERS Oxygen Sensing: Life and Death of a Cell PKC- (cid:1) and TAK-1 are intermediates in the activation of c -Jun NH 2 -terminal kinase by hypoxia-reoxygenation

K. Webster, N. Bishopric, C. Dougherty, 2007 .

Metabolic Stress in Cardiac Myocytes

K. Webster, D. J. Discher, N. Bishopric, 2005 .

A unique pathway of cardiac myocyte death caused by hypoxia–acidosis

K. Webster, B. J. Wasserlauf, N. Bishopric, 2004, Journal of Experimental Biology.

Rapid activation of neutral sphingomyelinase by hypoxia-reoxygenation of cardiac myocytes.

K. Webster, D. J. Discher, N. Bishopric, 2000, Circulation research.

A glycolytic pathway to apoptosis of hypoxic cardiac myocytes. Molecular pathways of increased acid production.

K. Webster, D. J. Discher, K. Yamashita, 2000, Advances in experimental medicine and biology.

Hypoxia-activated apoptosis of cardiac myocytes requires reoxygenation or a pH shift and is independent of p53.

K. Webster, D. J. Discher, N. Bishopric, 1999, The Journal of clinical investigation.

Regulated expression of a foreign gene targeted to the ischaemic myocardium.

K. Webster, D. J. Discher, N. Bishopric, 1997, Cardiovascular research.

Cell-specificity and signaling pathway of endothelin-1 gene regulation by hypoxia.

K. Webster, D. J. Discher, N. Bishopric, 1995, Cardiovascular research.

Mesenchymal stem cell-derived IL-10 and recovery from infarction: a third pitch for the chord.

N. Bishopric, 2008, Circulation research.

Expression of inducible nitric oxide synthase in human heart failure.

P. Tsao, J. Cooke, P. Trindade, 1996, Circulation.

Nitric oxide and promotion of cardiac myocyte apoptosis

K. Webster, N. Bishopric, P. Andréka, 2004, Molecular and Cellular Biochemistry.

Apoptosis Inhibitors for Heart Disease

K. Webster, N. Bishopric, 2003, Circulation.

Modulation of cytokine-induced cardiac myocyte apoptosis by nitric oxide, Bak, and Bcl-x.

K. Webster, N. Bishopric, J. Zang, 1999, Circulation research.

Angiotensin Signaling and Apoptosis in the Neonatal Heart: Necessary Evils?: Commentary on the article by Choi et al. on page 325

N. Bishopric, 2002, Pediatric Research.

Trastuzumab-induced cardiotoxicity: a review of clinical risk factors, pharmacologic prevention, and cardiotoxicity of other HER2-directed therapies

N. Bishopric, M. Lippman, A. Rosenthal, 2021, Breast Cancer Research and Treatment.

Recurrent Third-Trimester Fetal Loss and Maternal Mosaicism for Long-QT Syndrome

R. Myerburg, N. Bishopric, G. Wolff, 2004, Circulation.

Cytoprotection by Jun Kinase During Nitric Oxide–Induced Cardiac Myocyte Apoptosis

K. Webster, N. Bishopric, J. Zang, 2001, Circulation research.

Molecular regulation of cardiac myocyte adaptations to chronic hypoxia.

K. Webster, N. Bishopric, Keith A. Webster, 1992, Journal of molecular and cellular cardiology.

The virtue of just enough stress: a molecular model.

N. Bishopric, 2012, Transactions of the American Clinical and Climatological Association.

Myocardial activation of the human cardiac alpha-actin promoter by helix-loop-helix proteins.

L. Kedes, N. Bishopric, V. Sartorelli, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Auto-acetylation stabilizes p300 in cardiac myocytes during acute oxidative stress, promoting STAT3 accumulation and cell survival

Sumit Jain, N. Bishopric, Jianqin Wei, 2012, Breast Cancer Research and Treatment.

Cardiac myocyte hypertrophy is associated with c-myc protooncogene expression.

S. Coughlin, P. Simpson, N. Bishopric, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Introducing JACC: Basic to Translational Science

P. Libby, G. Tomaselli, D. Mann, 2016, JACC. Basic to translational science.

Beta adrenergic receptors in lymphocyte subpopulations.

R. Lefkowitz, N. Bishopric, H. Cohen, 1980, The Journal of allergy and clinical immunology.

Genetic screening of cardiac syndromes

N. Bishopric, M. E. Ahearn, H. Elsayed, 2012 .

Atrial natriuretic peptide induces apoptosis in neonatal rat cardiac myocytes.

N. Bishopric, R. Pratt, C. F. Wu, 1996, The Journal of biological chemistry.

Adrenergic regulation of the skeletal alpha-actin gene promoter during myocardial cell hypertrophy.

L. Kedes, N. Bishopric, Larry Kedes, 1991, Proceedings of the National Academy of Sciences of the United States of America.

A longer, better ride with engineered stem cells.

N. Bishopric, 2012, Journal of the American College of Cardiology.

Coxsackie and adenovirus receptor is a modifier of cardiac conduction and arrhythmia vulnerability in the setting of myocardial ischemia.

R. Coronel, J. D. de Bakker, C. D. dos Remedios, 2014, Journal of the American College of Cardiology.

Angiotensin II receptor subtype AT1 and AT2 expression after heart transplantation.

N. Bishopric, H. Ross, J. Kjekshus, 1998, Cardiovascular research.

Angiotensin II receptor subtype AT and AT expression after heart 1 2 transplantation

N. Bishopric, H. Ross, J. Kjekshus, 1998 .

Beta-adrenergic regulation of a myocardial actin gene via a cyclic AMP-independent pathway.

K. Webster, N. Bishopric, B. Sato, 1992, The Journal of biological chemistry.

Mesenchymal stem cell-derived IL-10 and recovery from infarction: A third pitch for the MSC chord

N. Bishopric, 2009 .

Mesenchymal Stem Cell – Derived IL-10 and Recovery From Infarction

N. Bishopric, 2008 .

Abstract 1971: Genome-wide Association Study Identifies Novel Genomic Regions Associated With Drug-induced Long Qt Syndrome

Yusuke Nakamura, D. Roden, A. Pfeufer, 2009 .

Abstract 4412: High Density tagSNP Candidate Gene Analysis Identifies IKs as a Major Modulator of Genetic Susceptibility to Drug Induced Long QT Syndrome

T. Meitinger, H. Wichmann, D. Roden, 2008 .

Dual trophic effects of the alpha 1-adrenergic receptor in cultured neonatal rat heart muscle cells.

S. Coughlin, P. Simpson, N. Bishopric, 1986, Journal of molecular and cellular cardiology.

Apoptosis Inhibitors for Heart Disease Focused Perspective

K. Webster, N. Bishopric, 2003 .

Neuroprotective antioxidant STAZN protects against myocardial ischemia/reperfusion injury.

M. Ginsberg, N. Bishopric, R. Prado, 2008, Biochemical pharmacology.

Comparison of microsomal prostaglandin E synthase-1 deletion and COX-2 inhibition in acute cardiac ischemia in mice.

D. Mennerich, N. Bishopric, K. Sugiyama, 2009, Prostaglandins & other lipid mediators.

The effects of microsomal prostaglandin E synthase-1 deletion in acute cardiac ischemia in mice.

D. Mennerich, N. Bishopric, K. Sugiyama, 2009, Prostaglandins, leukotrienes, and essential fatty acids.

Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3

K. Webster, N. Bishopric, O. Hernandez, 2002, Proceedings of the National Academy of Sciences of the United States of America.

A novel RNA aptamer identifies plasma membrane ATP synthase beta subunit as an early marker and therapeutic target in aggressive cancer

S. Bicciato, N. Bishopric, M. Lippman, 2019, Breast Cancer Research and Treatment.

Whole blood RNA offers a rapid, comprehensive approach to genetic diagnosis of cardiovascular diseases

R. Myerburg, N. Bishopric, P. Benke, 2007, Genetics in Medicine.

Repression of miR-142 by p300 and MAPK is required for survival signalling via gp130 during adaptive hypertrophy

Salil Sharma, N. Bishopric, Taifang Zhang, 2012, EMBO molecular medicine.

A cardiac myocyte-restricted Lin28/let-7 regulatory axis promotes hypoxia-mediated apoptosis by inducing the AKT signaling suppressor PIK3IP1.

N. Bishopric, S. Joshi, Jianqin Wei, 2016, Biochimica et biophysica acta.

Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy

E. Petretto, Y. Pinto, E. Creemers, 2017, Genome Biology.

Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16

S. Heath, G. Lathrop, M. Farrall, 2013, Nature Genetics.

Genome Wide Analysis of Drug-Induced Torsades de Pointes: Lack of Common Variants with Large Effect Sizes

R. Altman, Yufeng Shen, Yusuke Nakamura, 2013, PloS one.

Jun Kinase Delays Caspase-9 Activation by Interaction with the Apoptosome*

K. Webster, N. Bishopric, C. O. Rodrigues, 2007, Journal of Biological Chemistry.

Activation of c-Jun N-terminal kinase promotes survival of cardiac myocytes after oxidative stress.

K. Webster, N. Bishopric, H. Prentice, 2002, The Biochemical journal.

Physical and functional sensitivity of zinc finger transcription factors to redox change

K. Webster, D. J. Discher, N. Bishopric, 1996, Molecular and cellular biology.

Hypoxia regulates expression of the endothelin-1 gene through a proximal hypoxia-inducible factor-1 binding site on the antisense strand.

K. Webster, D. J. Discher, N. Bishopric, 1998, Biochemical and biophysical research communications.

BNip3 and signal-specific programmed death in the heart.

K. Webster, N. Bishopric, R. Graham, 2005, Journal of molecular and cellular cardiology.

Mitochondrial signals initiate the activation of c‐Jun N‐terminal kinase (JNK) by hypoxia‐reoxygenation

K. Webster, N. Bishopric, W. Xiong, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Control of Cardiac-specific Transcription by p300 through Myocyte Enhancer Factor-2D*

K. Webster, N. Bishopric, J. Zang, 2001, The Journal of Biological Chemistry.

MicroRNA-20a Constrains p300-Driven Myocardial Angiogenic Transcription by Direct Targeting of p300

Salil Sharma, N. Tsinoremas, N. Bishopric, 2013, PloS one.

Atrial Natriuretic Peptide Induces Apoptosis in Neonatal Rat Cardiac Myocytes*

N. Bishopric, R. Pratt, Cancan Wu, 1997, The Journal of Biological Chemistry.

Analysis for Genetic Modifiers of Disease Severity in Patients With Long-QT Syndrome Type 2

T. Meitinger, D. Roden, A. Pfeufer, 2015, Circulation. Cardiovascular genetics.

Molecular aspects and gene therapy prospects for diastolic failure.

K. Webster, N. Bishopric, 2000, Cardiology clinics.

Oxidation of zinc finger transcription factors: physiological consequences.

K. Webster, N. Bishopric, H. Prentice, 2001, Antioxidants & redox signaling.

Reliable Detection of DNA CpG Methylation Profiles by the Isoschizomers Msp I / Hpa II Using Oligonucleotide Stimulators

N. Bishopric, R. Pratt, Cancan Wu, 1999 .

Induction of the Skeletal a-Actin Gene in a ,-Adrenoceptor-mediated Hypertrophy of Rat Cardiac Myocytes

P. Simpson, N. Bishopric, C. Ordahl, 2013 .

Identification of alpha-adrenergic receptors in human platelets by [3H]dihydroergocryptine binding.

R. Lefkowitz, N. Bishopric, L. Williams, 1978, Journal of Clinical Investigation.

Evolution of the Heart from Bacteria to Man

N. Bishopric, Nanette H Bishopric, 2005, Annals of the New York Academy of Sciences.

Reversal of pathological cardiac hypertrophy via the MEF2-coregulator interface.

Sumit Jain, N. Jayathilaka, N. Bishopric, 2017, JCI insight.

Induction of the skeletal alpha-actin gene in alpha 1-adrenoceptor-mediated hypertrophy of rat cardiac myocytes.

P. Simpson, N. Bishopric, C. Ordahl, 1987, The Journal of clinical investigation.

Preventing apoptosis with thioredoxin: ASK me how.

K. Webster, N. Bishopric, Nanette H Bishopric, 2002, Circulation research.

Expression of Lewy body protein septin 4 in postmortem brain of Parkinson's disease and control subjects

S. Papapetropoulos, N. Bishopric, Lina A. Shehadeh, 2009, Movement disorders : official journal of the Movement Disorder Society.

Toward a genomic definition of aspirin resistance.

N. Bishopric, 2013, Journal of the American College of Cardiology.

Transplantation of Stem Cells to the Heart:

R. Myerburg, N. Bishopric, 2003, Journal of cardiovascular electrophysiology.

Three‐dimensional reconstitution of embryonic cardiomyocytes in a collagen matrix: a new heart muscle model system

Thomas Eschenhagen, E. Elson, W. Zimmermann, 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A Growth Tonic for Heart Failure?

N. Bishopric, 2016, JACC. Basic to translational science.

Association between anti-human heat shock protein-60 and interleukin-2 with coronary artery calcium score

R. Hendel, Mauricio G. Cohen, R. Myerburg, 2015, Heart.

Possible therapeutic targets in cardiac myocyte apoptosis.

Z. Tulassay, N. Bishopric, M. Turner, 2004, Current pharmaceutical design.

Inhibition of p53 function prevents renin-angiotensin system activation and stretch-mediated myocyte apoptosis.

K. Webster, P. Anversa, A. Leri, 2000, The American journal of pathology.

Adenovirus E1A Inhibits Cardiac Myocyte-specific Gene Expression through Its Amino Terminus*

K. Webster, N. Bishopric, B. Sato, 1997, The Journal of Biological Chemistry.

Heterogeneity in SDF-1 Expression Defines the Vasculogenic Potential of Adult Cardiac Progenitor Cells

N. Tsinoremas, N. Bishopric, C. O. Rodrigues, 2011, PloS one.

Is the G2019S LRRK2 mutation common in all southern European populations?

C. Singer, N. Bishopric, A. Argyriou, 2008, Journal of Clinical Neuroscience.

Instability of a multiple copy enhancer in plasmid vectors: practical considerations.

K. Webster, D. J. Discher, N. Bishopric, 1999, BioTechniques.

Sex Differences in Science

E. van Rooij, N. Bishopric, 2019, JACC. Basic to translational science.

Inflammation, stem cells and atherosclerosis genetics.

M. Pericak-Vance, J. Vance, G. Beecham, 2010, Current opinion in molecular therapeutics (Print).

A thousand times NO.

N. Bishopric, 2002, Journal of molecular and cellular cardiology.

Positive regulation of the skeletal alpha-actin gene by Fos and Jun in cardiac myocytes.

K. Webster, N. Bishopric, V. Jayasena, 1992, The Journal of biological chemistry.

Dysfunctional potassium channel subunit interaction as a novel mechanism of long QT syndrome.

R. Myerburg, N. Bishopric, A. Farooq, 2013, Heart rhythm.

Genome-wide association study identifies a susceptibility locus at 21q21 for ventricular fibrillation in acute myocardial infarction

X. Jouven, S. Chugh, T. Meitinger, 2010, Nature Genetics.

COMBINATION CELL AND GENE THERAPY FOR PERIPHERAL ISCHEMIA USING MYOBLASTS AND STEM CELLS ENGINEERED WITH CONDITIONALLY SILENCED GENES

T. Yeasky, N. Bishopric, F. Andreopoulos, 2005 .