M. Hetman

发表

Signaling pathways mediating anti-apoptotic action of neurotrophins.

Z. Xia, M. Hetman, M. Hetman, 2000, Acta neurobiologiae experimentalis.

Requirement of 3-Phosphoinositide-Dependent Protein Kinase-1 for BDNF-Mediated Neuronal Survival

M. Hetman, G. Kharebava, Denys Y. Makonchuk, 2008, The Journal of Neuroscience.

Role of extracellular signal regulated kinases 1 and 2 in neuronal survival.

M. Hetman, A. Góźdź, 2004, European journal of biochemistry.

Inducible cAMP Early Repressor, an Endogenous Antagonist of cAMP Responsive Element-Binding Protein, Evokes Neuronal Apoptosis In Vitro

L. Kaczmarek, J. Mallet, J. Jaworski, 2003, The Journal of Neuroscience.

Direct Mechanical Measurement of the Tensile Strength and Elastic Modulus of Multiwalled Carbon Nanotubes

Yang Wang, R. Ritchie, A. Zettl, 2002, Microscopy and Microanalysis.

Epigenetic Silencing of Nucleolar rRNA Genes in Alzheimer's Disease

P. Nelson, G. Rempała, M. Hetman, 2011, PloS one.

Blocking Autophagy in Oligodendrocytes Limits Functional Recovery after Spinal Cord Injury

D. Burke, S. Whittemore, M. Hetman, 2018, The Journal of Neuroscience.

Pharmacological inhibition of spinal cord injury-stimulated ribosomal biogenesis does not affect locomotor outcome

S. Whittemore, M. Laiho, M. Hetman, 2017, Neuroscience Letters.

Emerging roles of the neuronal nucleolus

M. Hetman, M. Pietrzak, 2012, Trends in Neurosciences.

Oligodendrocyte‐specific deletion of Xbp1 exacerbates the endoplasmic reticulum stress response and restricts locomotor recovery after thoracic spinal cord injury

Courtney T Shepard, S. Whittemore, M. Hetman, 2020, Glia.

Inhibition of GADD34, the Stress-Inducible Regulatory Subunit of the Endoplasmic Reticulum Stress Response, Does Not Enhance Functional Recovery after Spinal Cord Injury

S. Whittemore, M. Hetman, Sujata Saraswat Ohri, 2014, PloS one.

Proapoptotic Requirement of Ribosomal Protein L11 in Ribosomal Stress-Challenged Cortical Neurons

S. Ellis, M. Hetman, A. Vashishta, 2016, Molecular Neurobiology.

Nucleolar disruption and apoptosis are distinct neuronal responses to etoposide‐induced DNA damage

M. Hetman, M. Pietrzak, Cynthia Gomes, 2011, Journal of neurochemistry.

Institutional Animal Care and Use Committee protocols and the National Institutes of Health . Spinal Cord Injury

S. Whittemore, M. Hetman, S. Ohri, 2012 .

Inhibitors of Histone Deacetylases Enhance Neurotoxicity of DNA Damage

M. Hetman, A. Vashishta, 2014, NeuroMolecular Medicine.

Nucleolar Enrichment of Brain Proteins with Critical Roles in Human Neurodevelopment*

M. Hetman, Jing-Juan Zheng, M. Dadlez, 2016, Molecular & Cellular Proteomics.

Ca2+-dependent Translocation of the Calcyclin-binding Protein in Neurons and Neuroblastoma NB-2a Cells*

J. Kuźnicki, M. Hetman, K. Kwiatkowska, 2002, The Journal of Biological Chemistry.

Ca 2-dependent Translocation of the Calcyclin-binding Protein in Neurons and Neuroblastoma NB2 a Cells *

J. Kuźnicki, M. Hetman, K. Kwiatkowska, 2002 .

Rolipram attenuates acute oligodendrocyte death in the adult rat ventrolateral funiculus following contusive cervical spinal cord injury

D. Magnuson, M. Hetman, S. M. Onifer, 2008, Neuroscience Letters.

bovine neonatal pulmonary artery smooth muscle cells Mechanisms regulating cAMP-mediated growth of

Scott T. Wong, D. Storm, L. Suzuki, 2006 .

DNA fragmentation in rat brain after intraperitoneal administration of kainate

L. Kaczmarek, B. Kamińska, M. Hetman, 1994, Neuroreport.

Role of extracellular signal regulated kinases in neuronal death and survival

M. Hetman, 2004 .

Role of N-Methyl-d-aspartate Receptors in the Neuroprotective Activation of Extracellular Signal-regulated Kinase 1/2 by Cisplatin*

J. Jaworski, M. Hetman, A. Góźdź, 2003, Journal of Biological Chemistry.

Ribosomal stress and Tp53-mediated neuronal apoptosis in response to capsid protein of the Zika virus

M. Hetman, N. Boyd, L. Slomnicki, 2017, Scientific Reports.

Neurodegeneration-associated instability of ribosomal DNA.

P. Nelson, G. Rempała, M. Hetman, 2014, Biochimica et biophysica acta.

Mechanisms of ammonia-induced cell death in rat cortical neurons: Roles of NMDA receptors and glutathione

M. Hetman, B. Mioduszewska, E. Szatmari, 2005, Neurochemistry International.

Improved locomotor recovery after contusive spinal cord injury in Bmal1−/− mice is associated with protection of the blood spinal cord barrier

J. Chariker, S. Whittemore, E. Rouchka, 2020, Scientific Reports.

Neuroprotection by Brain-derived Neurotrophic Factor Is Mediated by Extracellular Signal-regulated Kinase and Phosphatidylinositol 3-Kinase*

Z. Xia, M. Hetman, Jane E. Cavanaugh, 1999, The Journal of Biological Chemistry.

Antioxidant Protection of NADPH-Depleted Oligodendrocyte Precursor Cells Is Dependent on Supply of Reduced Glutathione

S. Whittemore, M. Hetman, Sujata Saraswat Ohri, 2016, ASN neuro.

Calcyclin‐binding protein/Siah‐1‐interacting protein as a regulator of transcriptional responses in brain cells

M. Hetman, A. Filipek, E. Kilańczyk, 2015, Journal of neuroscience research.

Activating Transcription Factor-6α Deletion Modulates the Endoplasmic Reticulum Stress Response after Spinal Cord Injury but Does Not Affect Locomotor Recovery.

S. Whittemore, M. Hetman, Sujata Saraswat Ohri, 2017, Journal of neurotrauma.

The Proteostasis Network: A Global Therapeutic Target for Neuroprotection after Spinal Cord Injury

S. Whittemore, M. Hetman, Michael D Forston, 2022, Cells.

Acute Neural and Proteostasis Messenger Ribonucleic Acid Levels Predict Chronic Locomotor Recovery after Contusive Spinal Cord Injury

D. Burke, S. Whittemore, M. Hetman, 2021 .

Deletion of the pro-apoptotic endoplasmic reticulum stress response effector CHOP does not result in improved locomotor function after severe contusive spinal cord injury.

S. Whittemore, M. Hetman, S. Ohri, 2012, Journal of neurotrauma.

Zika virus infects pericytes in the choroid plexus and enters the central nervous system through the blood-cerebrospinal fluid barrier

M. Hetman, H. Ishikawa, H. Schroten, 2019, bioRxiv.

Acute pharmacological inhibition of PERK signaling after spinal cord injury spares oligodendrocytes and improves locomotor recovery.

S. Whittemore, M. Hetman, Michael D Forston, 2022, Journal of neurotrauma.

Effects of rolipram on adult rat oligodendrocytes and functional recovery after contusive cervical spinal cord injury

D. Burke, M. Hetman, S. M. Onifer, 2009, Neuroscience.

Limited changes in locomotor recovery and unaffected white matter sparing after spinal cord contusion at different times of day

D. Burke, S. Whittemore, M. Hetman, 2021, PloS one.

Annonacin in Asimina triloba fruit: implication for neurotoxicity.

I. Litvan, M. Hetman, Lisa F. Potts, 2012, Neurotoxicology.

Neurotoxic mechanisms of DNA damage: focus on transcriptional inhibition

M. Hetman, A. Vashishta, Grzegorz A. Rempala, 2010, Journal of neurochemistry.

The catalytic machinery of the FAD-dependent AtBBE-like protein 15 for alcohol oxidation: Y193 and Y479 form a catalytic base, Q438 and R292 an alkoxide binding site.

K. Gruber, M. Hetman, Julia Messenlehner, 2021, Archives of biochemistry and biophysics.

Role of Megakaryoblastic Acute Leukemia-1 in ERK1/2-Dependent Stimulation of Serum Response Factor-Driven Transcription by BDNF or Increased Synaptic Activity

M. Hetman, G. Kharebava, Katarzyna Kalita, 2006, The Journal of Neuroscience.

p38 Map Kinase Mediates Bax Translocation in Nitric Oxide–Induced Apoptosis in Neurons

S. Larner, Z. Xia, M. Hetman, 2000, The Journal of cell biology.

Taxol Induces Apoptosis in Cortical Neurons by a Mechanism Independent of Bcl-2 Phosphorylation

Z. Xia, M. Hetman, M. Higgins, 2001, The Journal of Neuroscience.

RNA Polymerase 1-driven Transcription as a Mediator of BDNF-induced Neurite Outgrowth*

M. Hetman, Cynthia Gomes, T. Hagg, 2010, The Journal of Biological Chemistry.

Mice Deficient in Lysosomal Acid Phosphatase Develop Lysosomal Storage in the Kidney and Central Nervous System*

C. Peters, R. Lüllmann-Rauch, D. Hartmann, 1997, The Journal of Biological Chemistry.

Role of Kinase Suppressor of Ras-1 in Neuronal Survival Signaling by Extracellular Signal-Regulated Kinase 1/2

M. Hetman, G. Kharebava, E. Szatmari, 2007, The Journal of Neuroscience.

Differential Regulation of Mitogen-Activated Protein Kinases ERK1/2 and ERK5 by Neurotrophins, Neuronal Activity, and cAMP in Neurons

S. Poser, Z. Xia, M. Hetman, 2001, The Journal of Neuroscience.

RNA Polymerase 1 Is Transiently Regulated by Seizures and Plays a Role in a Pharmacological Kindling Model of Epilepsy

Murali K. Kolikonda, R. Parlato, M. Hetman, 2018, Molecular Neurobiology.

Ribosomal biogenesis as an emerging target of neurodevelopmental pathologies

M. Hetman, L. Slomnicki, 2018, Journal of neurochemistry.

Inhibition of nucleolar transcription as a trigger for neuronal apoptosis

M. Hetman, Denys Y. Makonchuk, Cynthia Gomes, 2008, Journal of neurochemistry.

Nuclear Factor of Activated T-Cells Isoform c4 (NFATc4/NFAT3) as a Mediator of Antiapoptotic Transcription in NMDA Receptor-Stimulated Cortical Neurons

M. Hetman, Agata Habas, T. Timmusk, 2009, The Journal of Neuroscience.

Cisplatin‐mediated activation of extracellular signal‐regulated kinases 1/2 (ERK1/2) by inhibition of ERK1/2 phosphatases

M. Hetman, A. Góźdź, E. Szatmari, 2008, Journal of neurochemistry.

Nucleolar Contributions to DNA-Damage Response and Genomic (In)Stability in the Nervous System

M. Hetman, 2016 .

Inhibitors of Histone Deacetylases Enhance Neurotoxicity of DNA Damage

M. Hetman, A. Vashishta, bullet M Hetman, 2014, NeuroMolecular Medicine.

A Positive Feedback Loop between Glycogen Synthase Kinase 3β and Protein Phosphatase 1 after Stimulation of NR2B NMDA Receptors in Forebrain Neurons*

M. Hetman, Agata Habas, E. Szatmari, 2005, Journal of Biological Chemistry.

DNA Methyltransferase 3a and Mitogen-activated Protein Kinase Signaling Regulate the Expression of Fibroblast Growth Factor-inducible 14 (Fn14) during Denervation-induced Skeletal Muscle Atrophy*

Ashok Kumar, M. Hetman, M. Tajrishi, 2014, The Journal of Biological Chemistry.

Requirement of Neuronal Ribosome Synthesis for Growth and Maintenance of the Dendritic Tree*

M. Hetman, A. Vashishta, M. Pietrzak, 2016, The Journal of Biological Chemistry.

Survival signaling pathways activated by NMDA receptors.

M. Hetman, G. Kharebava, 2006, Current topics in medicinal chemistry.

Neuronal Excitation-driven and AP-1-dependent Activation of Tissue Inhibitor of Metalloproteinases-1 Gene Expression in Rodent Hippocampus*

L. Kaczmarek, J. Jaworski, M. Hetman, 1999, The Journal of Biological Chemistry.

Role of Glycogen Synthase Kinase-3β in Neuronal Apoptosis Induced by Trophic Withdrawal

D. Kimelman, Z. Xia, M. Hetman, 2000, The Journal of Neuroscience.

Hypoxia-inducible factor prolyl hydroxylase domain (PHD) inhibition after contusive spinal cord injury does not improve locomotor recovery

S. Whittemore, M. Hetman, S. Karuppagounder, 2021, PloS one.

Ciliary Neurotrophic Factor Mediates Dopamine D2 Receptor-Induced CNS Neurogenesis in Adult Mice

M. Hetman, Agata Habas, T. Hagg, 2008, The Journal of Neuroscience.

ERK1/2 Antagonizes Glycogen Synthase Kinase-3β-induced Apoptosis in Cortical Neurons*

Z. Xia, M. Hetman, S. Hsuan, 2002, The Journal of Biological Chemistry.

Adenylyl Cyclase 3 Mediates Prostaglandin E2-induced Growth Inhibition in Arterial Smooth Muscle Cells*

Scott T. Wong, D. Storm, L. Suzuki, 2001, The Journal of Biological Chemistry.

NMDA neuroprotection against a phosphatidylinositol‐3 kinase inhibitor, LY294002 by NR2B‐mediated suppression of glycogen synthase kinase‐3β‐induced apoptosis

M. Hetman, G. Kharebava, Agata Habas, 2006, Journal of neurochemistry.

Activating Transcription Factor-6α Deletion Modulates the Endoplasmic Reticulum Stress Response after Spinal Cord Injury but Does Not Affect Locomotor Recovery.

S. Whittemore, M. Hetman, Sujata Saraswat Ohri, 2016, Journal of neurotrauma.

Restoring endoplasmic reticulum homeostasis improves functional recovery after spinal cord injury

Scott R. Whittemore, S. Whittemore, M. Hetman, 2013, Neurobiology of Disease.

Elevated Cathepsin D Expression in Kainate-Evoked Rat Brain Neurodegeneration

L. Kaczmarek, M. Hetman, R. Filipkowski, 1995, Experimental Neurology.

Plasticity- and neurodegeneration-linked cyclic-AMP responsive element modulator/inducible cyclic-AMP early repressor messenger RNA expression in the rat brain

L. Kaczmarek, M. Hetman, R. Filipkowski, 1998, Neuroscience.

Increased Expression of Cathepsin D in Retrosplenial Cortex of MK-801-Treated Rats

Leszek Kaczmarek, L. Kaczmarek, W. Danysz, 1997, Experimental Neurology.

Kainate-evoked modulation of gene expression in rat brain.

L. Kaczmarek, B. Kamińska, M. Hetman, 1997, Acta biochimica Polonica.

Downregulation of cholesterol biosynthesis genes in the forebrain of ERCC1-deficient mice

M. Hetman, L. Niedernhofer, A. Robinson, 2012, Neurobiology of Disease.

Activity/exercise-induced changes in the liver transcriptome after chronic spinal cord injury

Kathryn M. DeVeau, J. Chariker, D. Magnuson, 2019, Scientific Data.

Non-random distribution of methyl-CpG sites and non-CpG methylation in the human rDNA promoter identified by next generation bisulfite sequencing.

P. Nelson, G. Rempała, M. Hetman, 2016, Gene.

Non-random distribution of methyl-CpG sites and non-CpG methylation in the human rDNA promoter identified by next generation bisulfite sequencing Running title : DNA methylation patterns of the human rDNA promoter

P. Nelson, G. Rempała, M. Hetman, 2017 .

Opposite modulation of functional recovery following contusive spinal cord injury in mice with oligodendrocyte-selective deletions of Atf4 and Chop/Ddit3

J. Chariker, D. Burke, S. Whittemore, 2023, Scientific reports.

RNA Polymerase 1 Is Transiently Regulated by Seizures and Plays a Role in a Pharmacological Kindling Model of Epilepsy

Murali K. Kolikonda, R. Parlato, M. Hetman, 2018, Molecular Neurobiology.

Enhanced oxidative phosphorylation, re-organized intracellular signaling, and epigenetic de-silencing as revealed by oligodendrocyte translatome analysis after contusive spinal cord injury

J. Chariker, S. Whittemore, E. Rouchka, 2023, Research square.

Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells.

C. Peters, P. Saftig, K. Figura, 1995, EMBO Journal.

Activation of MAPK and FoxO by Manganese (Mn) in Rat Neonatal Primary Astrocyte Cultures

K. Wells, M. Aschner, M. Hetman, 2014, PloS one.

Associations between diurnal timing of spinal cord injury and its etiology and co-morbidities.

M. Boakye, S. Whittemore, M. Hetman, 2023, Journal of neurotrauma.

Intraspinal Application of Endothelin Results in Focal Ischemic Injury of Spinal Gray Matter and Restricts the Differentiation of Engrafted Neural Stem Cells

S. Whittemore, M. Hetman, E. Gozal, 2005, Neurochemical Research.

Role of circadian rhythms in pathogenesis of acute CNS injuries: Insights from experimental studies

S. Whittemore, E. Hodges, M. Hetman, 2022, Experimental Neurology.

Unaffected functional recovery after spinal cord contusions at different circadian times

D. Burke, S. Whittemore, M. Hetman, 2021, bioRxiv.

RNA Polymerase 1-driven Transcription as a Mediator of BDNF-induced Neurite Outgrowth*

M. Hetman, Cynthia Gomes, T. Hagg, 2010, Journal of Biological Chemistry.

Restoring endoplasmic reticulum homeostasis improves functional recovery after spinal cord injury

S. Whittemore, M. Hetman, S. Ohri, 2013, Neurobiology of Disease.

Rolipram attenuates acute oligodendrocyte death in the adult rat ventrolateral funiculus following contusive cervical spinal cord injury

D. Magnuson, M. Hetman, S. M. Onifer, 2008, Neuroscience Letters.

Behavioural evaluation of long-term neurotoxic effects of NMDA receptor antagonists

L. Kaczmarek, W. Danysz, M. Hetman, 1999, Neurotoxicity Research.

Activating Transcription Factor-6 a Deletion Modulates the Endoplasmic Reticulum Stress Response after Spinal Cord Injury but Does Not Affect Locomotor Recovery

S. Whittemore, M. Hetman, S. Ohri, 2018 .

Activity/exercise-induced changes in the liver transcriptome after chronic spinal cord injury

Kathryn M. DeVeau, J. Chariker, D. Magnuson, 2019, Scientific Data.

Carboxypeptidase E-ΔN, a Neuroprotein Transiently Expressed during Development Protects Embryonic Neurons against Glutamate Neurotoxicity

Y. Loh, M. Hetman, S. Murthy, 2014, PloS one.