Ling-mei Wang

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Cyclic Nucleotide Phosphodiesterase 3B Is a Downstream Target of Protein Kinase B and May Be Involved in Regulation of Effects of Protein Kinase B on Thymidine Incorporation in FDCP2 Cells

M. Quon, E. Degerman, V. Manganiello, 2000 .

An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth

W. Paul, M. White, Ling-mei Wang, 1994, Cell.

Transgenic Expression of Insulin Receptor Substrate 2 in Murine B Cells Alters the Cell Density-Dependence of IgE Production In Vitro and Enhances IgE Production In Vivo1

F. Finkelman, G. Jay, Ling-mei Wang, 2004, The Journal of Immunology.

Vitro and Enhances IgE Production In Vivo Density-Dependence of IgE Production In Substrate 2 in Murine B Cells Alters the Cell Transgenic Expression of Insulin Receptor

F. Finkelman, G. Jay, Ling-mei Wang, 2004 .

Different Mechanisms in FDCP 2 Myeloid byPhosphodiesterases 3 ( PDE 3 ) and 4 ( PDE 4 ) IL-3 and IL-4 Activate Cyclic Nucleotide

E. Degerman, V. Manganiello, T. Landstrom, 1999 .

Quercetin inhibition of tumor invasion via suppressing PKC delta/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells.

Ling-mei Wang, S. Shen, W. Hou, 2008, Carcinogenesis.

The kinase insert domain of colony stimulating factor‐1 receptor is dispensable for CSF‐1 induced phosphatidylcholine hydrolysis

V. Sylvia, G. G. Choudhury, Ling-mei Wang, 1991, FEBS letters.

The Pleckstrin Homology Domain in Insulin Receptor Substrate-1 Sensitizes Insulin Signaling (*)

J. Blenis, M. White, Ling-mei Wang, 1995, The Journal of Biological Chemistry.

Signal transduction through the IL‐4 and insulin receptor families

W. Paul, Ling-mei Wang, J. Pierce, 1995, Stem cells.

Jak1 Expression Is Required for Mediating Interleukin-4-induced Tyrosine Phosphorylation of Insulin Receptor Substrate and Stat6 Signaling Molecules*

R. Flavell, Ling-mei Wang, J. Pierce, 1997, The Journal of Biological Chemistry.

Novel azulene-based derivatives as potent multi-receptor tyrosine kinase inhibitors.

Ling-mei Wang, Chung‐Cheng Liu, Chih-Lung Lin, 2010, Bioorganic & medicinal chemistry letters.

Mutation of Tyrosine 960 within the Insulin Receptor Juxtamembrane Domain Impairs Glucose Transport but Does Not Inhibit Ligand-mediated Phosphorylation of Insulin Receptor Substrate-2 in 3T3-L1 Adipocytes*

Y. Ebina, Ling-mei Wang, J. Pierce, 1999, The Journal of Biological Chemistry.

The Insulin Receptor Substrate-l-Related 4PS Substrate But Not the Interleukin-2Ry Chain Is Involved in Interleukin-13-Mediated Signal Transduction

A. Minty, Ling-mei Wang, J. Pierce, 2000 .

Role of IRS-2 in insulin and cytokine signalling

William Arbuthnot Sir Lane, M. White, L. Yenush, 1995, Nature.

Mitogenic signal transduction in normal and transformed 32D hematopoietic cells

M. Ruggiero, Ling-mei Wang, J. Pierce, 1991, FEBS letters.

ErbB Tyrosine Kinases and the Two Neuregulin Families Constitute a Ligand-Receptor Network

M. Eisenstein, Y. Yarden, S. Bacus, 1998, Molecular and Cellular Biology.

The Proto-oncogene Product c-Crk Associates with Insulin Receptor Substrate-1 and 4PS

D. Leroith, Ling-mei Wang, J. Pierce, 1996, The Journal of Biological Chemistry.

cbl-b inhibits epidermal growth factor receptor signaling

M. Nau, S. Lipkowitz, S. Ettenberg, 1999, Oncogene.

Met protein expression level correlates with survival in patients with late-stage nasopharyngeal carcinoma.

B. Teh, G. V. Vande Woude, J. Resau, 2002, Cancer research.

Activating Met mutations produce unique tumor profiles in mice with selective duplication of the mutant allele.

M. Fiscella, G. V. Vande Woude, R. Bronson, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Patients with Late-stage Nasopharyngeal Carcinoma Met Protein Expression Level Correlates with Survival in Updated

B. Teh, G. Woude, J. Resau, 2002 .

Insulin Receptor Substrate-2 Is the Major 170-kDa Protein Phosphorylated on Tyrosine in Response to Cytokines in Murine Lymphohemopoietic Cells*

M. Welham, Ling-mei Wang, L. M. Wang, 1997, The Journal of Biological Chemistry.

Interaction of Insulin Receptor Substrate-2 (IRS-2) with the Insulin and Insulin-like Growth Factor I Receptors

Ling-mei Wang, J. Pierce, Youyan Zhu, 1996, The Journal of Biological Chemistry.

Overexpression of sprouty 2 inhibits HGF/SF-mediated cell growth, invasion, migration, and cytokinesis

G. Woude, Chongfeng Gao, Ling-mei Wang, 2004, Oncogene.

Requirement of Stat3 signaling for HGF/SF-Met mediated tumorigenesis

R. Jove, G. Woude, Ling-mei Wang, 2002, Oncogene.

Radioimmunoscintigraphy of human met-expressing tumor xenografts using met3, a new monoclonal antibody.

G. V. Vande Woude, J. Resau, Ling-mei Wang, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Interleukins 2, 4, 7, and 15 Stimulate Tyrosine Phosphorylation of Insulin Receptor Substrates 1 and 2 in T Cells POTENTIAL ROLE OF JAK KINASES (*)

J. Johnston, M. White, J. O’Shea, 1995, The Journal of Biological Chemistry.

Enhanced growth of human met-expressing xenografts in a new strain of immunocompromised mice transgenic for human hepatocyte growth factor/scatter factor

G. Woude, N. Shinomiya, Ling-mei Wang, 2005, Oncogene.

Selecting Tyrosine Kinase Inhibitors for Gastrointestinal Stromal Tumor with Secondary KIT Activation-Loop Domain Mutations

Chien-Feng Li, Ling-mei Wang, Li‐Tzong Chen, 2013, PloS one.

Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal models

G. V. Vande Woude, R. Fisher, Ling-mei Wang, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Epidermal growth factor and betacellulin mediate signal transduction through co‐expressed ErbB2 and ErbB3 receptors

P. Fedi, Careen K. Tang, Ling-mei Wang, 1997, The EMBO journal.

Stat6 and Jak1 Are Common Elements in Platelet-derived Growth Factor and Interleukin-4 Signal Transduction Pathways in NIH 3T3 Fibroblasts*

Ling-mei Wang, J. Pierce, W. Larochelle, 1996, The Journal of Biological Chemistry.

Mitogenic synergy through multilevel convergence of hepatocyte growth factor and interleukin-4 signaling pathways

S. Corey, R. Day, Ling-mei Wang, 2002, Oncogene.

Epiregulin Is a Potent Pan-ErbB Ligand That Preferentially Activates Heterodimeric Receptor Complexes*

Y. Yarden, S. Bacus, Ling-mei Wang, 1998, The Journal of Biological Chemistry.

Differential proteomic analysis of cancer stem cell properties in hepatocellular carcinomas by isobaric tag labeling and mass spectrometry.

Ling-mei Wang, Chieh-Fang Cheng, Hsiang-Wen Tseng, 2013, Journal of proteome research.

Effect of X-ray radiation on the pharmacokinetics of apatinib in vivo in rats

Ling-mei Wang, Hui-rong Fan, Shiyang Dong, 2022, Frontiers in Pharmacology.

Differential Requirement of a Motif within the Carboxyl-terminal Domain of α-Platelet-derived Growth Factor (αPDGF) Receptor for PDGF Focus Forming Activity Chemotaxis, or Growth (*)

Weiqun Li, Ling-mei Wang, J. Pierce, 1995, The Journal of Biological Chemistry.

Synthesis and structure-activity relationship of 6-arylureido-3-pyrrol-2-ylmethylideneindolin-2-one derivatives as potent receptor tyrosine kinase inhibitors.

J. Chern, Ling-mei Wang, Chiung-Hua Huang, 2010, Bioorganic & medicinal chemistry.

ErbB Tyrosine Kinases and the Two Neuregulin Families Constitute a Ligand-Receptor Network

M. Eisenstein, Y. Yarden, S. Bacus, 1998, Molecular and Cellular Biology.

The IRS-2 gene on murine chromosome 8 encodes a unique signaling adapter for insulin and cytokine action.

N. Copeland, N. Jenkins, M. White, 1997, Molecular endocrinology.

Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus.

U. Smith, C. Rondinone, Ling-mei Wang, 1997, Proceedings of the National Academy of Sciences of the United States of America.

YMXM motifs and signaling by an insulin receptor substrate 1 molecule without tyrosine phosphorylation sites

J. Blenis, M. White, L. Yenush, 1996, Molecular and cellular biology.

IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells.

M. White, S. Aaronson, Ling-mei Wang, 1993, Science.

Activation of the colony-stimulating factor 1 receptor leads to the rapid tyrosine phosphorylation of GTPase-activating protein and activation of cellular p21ras.

T. Fleming, C. Molloy, G. G. Choudhury, 1992, Oncogene.

Insulin receptor substrate-1 mediates phosphatidylinositol 3'-kinase and p70S6k signaling during insulin, insulin-like growth factor-1, and interleukin-4 stimulation.

J. Blenis, M. White, Ling-mei Wang, 1994, The Journal of biological chemistry.

ErbB2 expression increases the spectrum and potency of ligand-mediated signal transduction through ErbB4.

Ling-mei Wang, L. M. Wang, J. Pierce, 1998, Proceedings of the National Academy of Sciences of the United States of America.

IL-4 protects cells from apoptosis via the insulin receptor substrate pathway and a second independent signaling pathway.

Ling-mei Wang, L. M. Wang, J. Pierce, 1996, Journal of immunology.

Tyrosine phosphorylation of protein kinase C-delta in response to its activation.

H. Mischak, Ling-mei Wang, L. M. Wang, 1994, The Journal of biological chemistry.

Radioimmunoscintigraphy of tumors autocrine for human met and hepatocyte growth factor/scatter factor.

G. Woude, Ling-mei Wang, Rick V. Hay, 2002, Molecular imaging.

Common elements in interleukin 4 and insulin signaling pathways in factor-dependent hematopoietic cells.

G. Lienhard, M. White, S. Aaronson, 1993, Proceedings of the National Academy of Sciences of the United States of America.

The insulin receptor substrate-1-related 4PS substrate but not the interleukin-2R gamma chain is involved in interleukin-13-mediated signal transduction.

M. White, A. Minty, Ling-mei Wang, 1995, Blood.

IL‐4 activates a distinct signal transduction cascade from IL‐3 in factor‐dependent myeloid cells.

J. Gutkind, Ling-mei Wang, A. Keegan, 1992, The EMBO journal.