Wei Huang

发表

Efficient synthesis and antiproliferative activity of novel thioether-substituted flavonoids.

Wei Huang, Qiong Chen, Wenchao Yang, 2013, European journal of medicinal chemistry.

Synthesis and antitumor activity of novel dithiocarbamate substituted chromones.

Wei Huang, Guang-Fu Yang, Yu Ding, 2009, European journal of medicinal chemistry.

Design, syntheses, and antitumor activity of novel chromone and aurone derivatives.

Wei Huang, Guang-Fu Yang, Ming-Zhen Liu, 2007, Bioorganic & medicinal chemistry.

Auto In Silico Ligand Directing Evolution to Facilitate the Rapid and Efficient Discovery of Drug Lead

Wei Huang, Guangfu Yang, Fan Wang, 2020, iScience.

Succinate Dehydrogenase: An Ideal Target for Fungicide Discovery

Li Xiong, Wei Huang, Wenchao Yang, 2015 .

Identification of 4-(2-furanyl)pyrimidin-2-amines as Janus kinase 2 inhibitors.

Wei Huang, L. Gui, Yazhou Wang, 2017, Bioorganic & medicinal chemistry.

Synthesis of polysubstituted 4-aminopyrazoles and 4-hydroxypyrazoles from vinyl azides and hydrazines

Wei Huang, Yongping Yu, Binhui Chen, 2015 .

2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: design and synthesis of a potent and isoform selective PKC-zeta inhibitor.

R. Compton, Wei Huang, A. Thorarensen, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of new MET inhibitors with 1,6-naphthyridinone scaffold.

Wenjun Wang, Wei Huang, Guangfu Yang, 2019, European journal of medicinal chemistry.

TBAI or KI-Promoted Oxidative Coupling of Enamines and N -Tosylhydrazine: An Unconventional Method toward 1,5- and 1,4,5-Substituted 1,2,3-Triazoles

Wei Huang, Huanfeng Jiang, Zheng-chao Tu, 2018, Advanced Synthesis & Catalysis.

Design, synthesis and evaluation of novel 5-phenylpyridin-2(1H)-one derivatives as potent reversible Bruton's tyrosine kinase inhibitors.

Yanliang Ren, Wei Huang, H. Xiang, 2015, Bioorganic & medicinal chemistry.

Synthesis and pharmacological evaluation of trifluoromethyl containing 4-(2-pyrimidinylamino)benzamides as Hedgehog signaling pathway inhibitors.

Wei Huang, Feng Tang, Q. Jin, 2016, Bioorganic & medicinal chemistry.

Discovery of potent anti-inflammatory 4-(4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-yl) pyrimidin-2-amines for use as Janus kinase inhibitors.

Wei Huang, Xinrong Zhu, L. Gui, 2019, Bioorganic & medicinal chemistry.

Construction of a combinatorial library of 2-(4-oxo-4H-1-benzopyran-3-yl)-4-thiazolidinones by microwave-assisted one-pot parallel syntheses

Wei Huang, Guang-Fu Yang, M. Ding, 2007 .

Conformational adjustment overcomes multiple drug-resistance mutants of tropomyosin receptor kinase.

Wei Huang, Guang-Fu Yang, Long-Can Mei, 2022, European journal of medicinal chemistry.

Pyrrolo[2,3-b]pyridine derivatives as potent Bruton's tyrosine kinase inhibitors.

Wei Huang, H. Xiang, Yazhou Wang, 2015, Bioorganic & medicinal chemistry.

Phosphonic acid-containing analogues of mycophenolic acid as inhibitors of IMPDH.

William A. Lee, Xiaohong Liu, James M. Chen, 2006, Bioorganic & medicinal chemistry letters.

Design, synthesis, and biological evaluation of pyrazinones containing novel P1 needles as inhibitors of TF/VIIa.

D. J. Garland, D. Reitz, Wei Huang, 2007, Bioorganic & medicinal chemistry letters.

Discovery of an Oral Potent Selective Inhibitor of Hematopoietic Prostaglandin D Synthase (HPGDS).

D. Rohrer, C. Carron, C. Wegner, 2010, ACS medicinal chemistry letters.

Discovery of 3-pyrazolyl-substituted pyrazolo[1,5-a]pyrimidine derivatives as potent TRK inhibitors to overcome clinically acquired resistance.

Wei Huang, Guang-Fu Yang, Feng-Xu Wu, 2022, European journal of medicinal chemistry.

Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (Part 2).

D. J. Garland, E. Reinhard, D. Reitz, 2005, Journal of medicinal chemistry.

Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (Part 1).

D. J. Garland, E. Reinhard, D. Reitz, 2005, Journal of medicinal chemistry.

Efficient Arylation of 2,7-Naphthyridin-1(2H)-one with Diaryliodonium Salts and Discovery of New Selective MET/AXL Kinase Inhibitor.

Wei Huang, Ming-Shu Wang, Ren-Yu Qu, 2020, ACS combinatorial science.

Structure-activity relationship study of novel quinazoline-based 1,6-naphthyridinones as MET inhibitors with potent antitumor efficacy.

Wei Huang, Xiao-Lei Zhu, Ming-Shu Wang, 2020, European journal of medicinal chemistry.

Synthesis and evaluation of 4-(2-pyrimidinylamino) benzamides inhibitors of hedgehog signaling pathway.

Wei Huang, Feng Tang, Minhang Xin, 2014, Bioorganic & medicinal chemistry letters.

An efficient one-pot access to N-(pyridin-2-ylmethyl) substituent biphenyl-4-sulfonamides through water-promoted, palladium-catalyzed, microwave-assisted reactions

Wei Huang, Guangfu Yang, Jing-Fang Yang, 2015 .

A novel improved procedure for the synthesis of oxazoles

Wei Huang, X. Ye, Jian Pei, 1996 .

A TREK Channel Family Activator with Well-Defined Structure-Activation Relationship for Pain and Neurogenic Inflammation.

Jie Fu, Wei Huang, F. Liu, 2020, Journal of medicinal chemistry.

Ag-Catalyzed Oxidative Cyclization Reaction of 1,6-Enynes and Sodium Sulfinate: Access to Sulfonylated Benzofurans.

Wei Huang, Huanfeng Jiang, Wanqing Wu, 2017, Organic letters.

Design and synthesis of novel CCR2 antagonists: investigation of non-aryl/heteroaryl binding motifs.

D. J. Rogier, Wei Huang, R. Devraj, 2011, Bioorganic & medicinal chemistry letters.

Triazole derivatives as non-nucleoside inhibitors of HIV-1 reverse transcriptase--structure-activity relationships and crystallographic analysis.

Wei Huang, M. Balakrishnan, T. Kirschberg, 2008, Bioorganic & medicinal chemistry letters.

Grignard Reagent Utilization Enables a Practical and Scalable Construction of 3-Substituted 5-Chloro-1,6-naphthyridin-4-one Derivatives

Wei Huang, Ming-Shu Wang, Nengfang She, 2020, Molecules.

Discovery of N-substituted-3-phenyl-1,6-naphthyridinone derivatives bearing quinoline moiety as selective type II c-Met kinase inhibitors against VEGFR-2.

Wei Huang, Nengfang She, Feng-Xu Wu, 2020, Bioorganic & medicinal chemistry.

Discovery of 1,6-naphthyridinone-based MET kinase inhibitor bearing quinoline moiety as promising antitumor drug candidate.

P. Liu, Wei Huang, Yunman Li, 2020, European journal of medicinal chemistry.

Discovery of 8-Amino-Substituted 2-Phenyl-2,7-Naphthyridinone Derivatives as New c-Kit/VEGFR-2 Kinase Inhibitors

Wei Huang, Haiyan Sun, Nengfang She, 2019, Molecules.

2,7-naphthyridinone-based MET kinase inhibitors: A promising novel scaffold for antitumor drug development.

Wei Huang, Guang-Fu Yang, Xiao-Lei Zhu, 2019, European journal of medicinal chemistry.

Design and synthesis of novel phthalazinone derivatives as potent poly(ADP-ribose)polymerase 1 inhibitors.

Wei Huang, Jiajia Sun, Feng Tang, 2020, Future medicinal chemistry.

Calcium carbide as the acetylide source: transition-metal-free synthesis of substituted pyrazoles via [1,5]-sigmatropic rearrangements

Wei Huang, Huanfeng Jiang, Wanqing Wu, 2016 .

Improved Synthesis of 2‐(3H)Benzothiazolethiones under Microwave Irradiation

Wei Huang, Guang-Fu Yang, Yin Tan, 2007 .

Microwave-assisted, one-pot syntheses and fungicidal activity of polyfluorinated 2-benzylthiobenzothiazoles.

Wei Huang, Guangfu Yang, 2006, Bioorganic & medicinal chemistry.

Design, synthesis and evaluation of highly selective pyridone-based class II MET inhibitors.

Wei Huang, Xiao-Lei Zhu, Zhi-Hui Ming, 2014, Bioorganic & medicinal chemistry letters.

Synthesis of N-glyoxyl prolyl and pipecolyl amides and thioesters and evaluation of their in vitro and in vivo nerve regenerative effects.

Wei Huang, Hong Guo, David C. Limburg, 2002, Journal of medicinal chemistry.

A Schiff-base porphyrin complex with double intramolecular hydrogen bonds

Wei Huang, Honggui Yu, Jiaxun Jiang, 2011 .

A Selective Transformation of Flavanones to 3‐Bromoflavones and Flavones Under Microwave Irradiation

Wei Huang, Guang-Fu Yang, Peiliang Zhao, 2006 .

Synthesis of Sulfonylated Lactones via Ag-Catalyzed Cascade Sulfonylation/Cyclization of 1,6-Enynes with Sodium Sulfinates.

Wei Huang, Huanfeng Jiang, Wanqing Wu, 2017, The Journal of organic chemistry.

One-Pot Synthesis of Spirocyclic or Fused Pyrazoles from Cyclic Ketones: Calcium Carbide as the Carbon Source in Ring Expansion.

Wei Huang, Huanfeng Jiang, Wanqing Wu, 2017, The Journal of organic chemistry.

Methyl 4,6-dichlorochroman-2-carboxylate

Wei Huang, Qiong Chen, Guangfu Yang, 2005 .

Me3 SiBr/InCl3 catalyzed allylation of alcohols: Identifying the combined Lewis structure and investigating the reaction mechanism

Wei Huang, Yan Yan, Shenglong Sang, 2018, Journal of Physical Organic Chemistry.

Design, synthesis, and fungicidal activities of new strobilurin derivatives.

Wei Huang, Qiong Chen, Guang-Fu Yang, 2007, Journal of agricultural and food chemistry.

Synthesis, fungicidal, and insecticidal activities of beta-Methoxyacrylate-containing N-acetyl pyrazoline derivatives.

Wei Huang, Guang-Fu Yang, Peiliang Zhao, 2008, Journal of agricultural and food chemistry.

Synthesis and fungicidal evaluation of novel chalcone-based strobilurin analogues.

Wei Huang, Guang-Fu Yang, Yazhou Wang, 2007, Journal of agricultural and food chemistry.

Improved Synthesis of 2-(3H)Benzothiazolethiones under Microwave Irradiation.

Wei Huang, Guang-Fu Yang, Yin Tan, 2007 .

Transition-metal-free synthesis of β-trifluoromethylated enamines with trifluoromethanesulfinate.

Wei Huang, Huanfeng Jiang, Wanqing Wu, 2017, Chemical communications.

Novel dual inhibitors of AChE and MAO derived from hydroxy aminoindan and phenethylamine as potential treatment for Alzheimer's disease.

Wei Huang, David Lerner, Sandor Molnar, 2002, Journal of medicinal chemistry.

Design, synthesis and molecular modeling of aloe-emodin derivatives as potent xanthine oxidase inhibitors.

Yu-Wei Liu, Wei Huang, D. Shi, 2014, European journal of medicinal chemistry.

Synthesis, biological evaluation and molecular modeling of aloe-emodin derivatives as new acetylcholinesterase inhibitors.

Wei Huang, D. Shi, Chao Li, 2013, Bioorganic & medicinal chemistry.

Synthesis, structural characterization, photoluminescence and thermal properties of [(Ph3P)2Cu(μ-SeC{O}R)2Cu(PPh3)]

Wei Huang, J. Vittal, Zheng Lu, 2002 .

Insights into SARS-CoV-2: Medicinal Chemistry Approaches to Combat Its Structural and Functional Biology

Wei Huang, Guang-Fu Yang, Ming-Shu Wang, 2021, Topics in Current Chemistry.

A chemical tuned strategy to develop novel irreversible EGFR-TK inhibitors with improved safety and pharmacokinetic profiles.

Wei Huang, Wenteng Chen, Jing-kang Shen, 2014, Journal of medicinal chemistry.

Investigation of the binding pocket of human hematopoietic prostaglandin (PG) D2 synthase (hH-PGDS): a tale of two waters.

Wei Huang, Atli Thorarensen, James R Kiefer, 2012, Bioorganic & medicinal chemistry letters.

Rational Design of Highly Potent and Slow-Binding Cytochrome bc1 Inhibitor as Fungicide by Computational Substitution Optimization

Ge-Fei Hao, Guang-Fu Yang, Wei Huang, 2015, Scientific Reports.

Synthesis, biological evaluation, and molecular docking studies of novel 2-styryl-5-nitroimidazole derivatives containing 1,4-benzodioxan moiety as FAK inhibitors with anticancer activity.

Zhong-Chang Wang, Wei Huang, Jigar A. Makawana, 2014, Bioorganic & medicinal chemistry.

One-pot three-component strategy for functionalized 2-aminoimidazoles via ring opening of α-nitro epoxides.

Wei Huang, Wenteng Chen, Guolin Zhang, 2015, Organic letters.

GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP).

Karen E Gascoigne, Y. Ran, G. Hatzivassiliou, 2017, Journal of medicinal chemistry.

Synthesis and biological evaluation of novel 7-substituted 3-(4-phenoxyphenyl)thieno[3,2-c]pyridin-4-amines as potent Bruton's tyrosine kinase (BTK) inhibitors.

Wei Huang, Wei Huang, H. Xiang, 2015, Bioorganic & medicinal chemistry.

Discovery of thieno[3,2-c]pyridin-4-amines as novel Bruton's tyrosine kinase (BTK) inhibitors.

Wei Huang, Wei Huang, H. Xiang, 2015, Bioorganic & medicinal chemistry.

Design, synthesis, and biological evaluation of novel 3-pyrrolo[b]cyclohexylene-2-dihydroindolinone derivatives as potent receptor tyrosine kinase inhibitors.

P. Wei, Wei Huang, Feng Tang, 2013, Bioorganic & medicinal chemistry letters.

Structure-Activity Study of Nitazoxanide Derivatives as Novel STAT3 Pathway Inhibitors.

T. Du, Wei Huang, Yan Niu, 2021, ACS medicinal chemistry letters.

Discovery of Next-Generation Tropomyosin Receptor Kinase Inhibitors for Combating Multiple Resistance Associated with Protein Mutation.

Wei Huang, Guang-Fu Yang, Ming-Shu Wang, 2021, Journal of medicinal chemistry.

Structure-Based Discovery of a Subtype-Selective Inhibitor Targeting a Transient Receptor Potential Vanilloid Channel.

Weiqiang Lu, Xi Cheng, Wei Huang, 2019, Journal of medicinal chemistry.

A catalase inhibitor: Targeting the NADPH-binding site for castration-resistant prostate cancer therapy

Yu Qin, Wei Huang, Guang-Fu Yang, 2023, Redox biology.

Discovery of Macrocycle-Based HPK1 Inhibitors for T-Cell-Based Immunotherapy.

Wei Huang, Guang-Fu Yang, Mingfang Wang, 2022, Journal of medicinal chemistry.

Distribution- and Metabolism-Based Drug Discovery: A Potassium-Competitive Acid Blocker as a Proof of Concept

Wei Huang, Guang-Fu Yang, Mingfang Wang, 2022, Research.

(4‐Oxo‐3,4‐dihydroquinazolin‐3‐yl)methyl piperidine‐1‐carbodithioate

Wei Huang, Nengfang She, 2007 .